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1

Ghrelin Receptor (GHS-R1A) Agonists Show Potential as Interventive Agents during Aging

ROY G. SMITH, YUXIANG SUN, HONG JIANG, ROSIE ALBARRAN-ZECKLER, NIKOLAI TIMCHENKO

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007

2

Iron-mediated regulation of liver hepcidin expression in rats and mice is abolished by alcohol

Duygu Dee Harrison-Findik, Elizabeth Klein, Callie Crist, John Evans, Nikolai Timchenko, John Gollan

Journal:

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

3

The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation

Jingling Jin, Polina Iakova, Yanjun Jiang, Estela E. Medrano, Nikolai A. Timchenko

Journal:

Year:

2011

Language:

english

File:

PDF, 920 KB

english, 2011

4

CCAAT/enhancer binding protein α (C/EBPα) is an important mediator of mouse C/EBPβ protein isoform production

Bonnie L. Burgess-Beusse, Nikolai A. Timchenko, Gretchen J. Darlington

Journal:

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

5

Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi

Debdutta Bandyopadhyay, Jonathan L. Curry, Qiushi Lin, Hunter W. Richards, Dahu Chen, Peter J. Hornsby, Nikolai A. Timchenko, Estela E. Medrano

Journal:

Year:

2007

Language:

english

File:

PDF, 687 KB

english, 2007

6

Epigenetic changes play critical role in age-associated dysfunctions of the liver

Jingling Jin, Guo-Li Wang, Polina Iakova, Xiurong Shi, Simon Haefliger, Milton Finegold, Nikolai A. Timchenko

Journal:

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

7

Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate

Iakova, Polina, Wang, Guo-Li, Timchenko, Lubov, Michalak, Marek, Pereira-Smith, Olivia M, Smith, James R, Timchenko, Nikolai A

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 694 KB

english, 2004

8

Differential regulation of cyclins D1 and D3 in hepatocyte proliferation

David G. Rickheim, Christopher J. Nelsen, John T. Fassett, Nikolai A. Timchenko, Linda K. Hansen, Jeffrey H. Albrecht

Journal:

Year:

2002

Language:

english

File:

PDF, 250 KB

english, 2002

9

C/EBPβ suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL

William T. Choi, Matthew R. Folsom, Mohammed F. Azim, Claus Meyer, Eric Kowarz, Rolf Marschalek, Nikolai A. Timchenko, Rizwan C. Naeem, Dean A. Lee

Journal:

Cancer Genetics and Cytogenetics

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

10

Role of HDAC1 in senescence, aging, and cancer

Danielle Willis-Martinez, Hunter W. Richards, Nikolai A. Timchenko, Estela E. Medrano

Journal:

Experimental Gerontology

Year:

2010

Language:

english

File:

PDF, 451 KB

english, 2010

11

Intracellular signaling and hepatocellular carcinoma

Polina Iakova, Lubov Timchenko, Nikolai A. Timchenko

Journal:

Seminars in Cancer Biology

Year:

2011

Language:

english

File:

PDF, 260 KB

english, 2011

12

Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

Julian A. Schardt, Marianne Eyholzer, Nikolai A. Timchenko, Beatrice U. Mueller, Thomas Pabst

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

13

RNA Foci, CUGBP1, and ZNF9 Are the Primary Targets of the Mutant CUG and CCUG Repeats Expanded in Myotonic Dystrophies Type 1 and Type 2

Karlie Jones, Bingwen Jin, Polina Iakova, Claudia Huichalaf, Partha Sarkar, Christiane Schneider-Gold, Benedikt Schoser, Giovanni Meola, Ann-Bin Shyu, Nikolai Timchenko, Lubov Timchenko

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.23 MB

english, 2011

14

Regulation of the promoter of CUG triplet repeat binding protein, Cugbp1, during myogenesis

Claudia H. Huichalaf, Keiko Sakai, Guo-Li Wang, Nikolai A. Timchenko, Lubov Timchenko

Journal:

Year:

2007

Language:

english

File:

PDF, 1.05 MB

english, 2007

15

Aging and liver regeneration

Nikolai A. Timchenko

Journal:

Trends in Endocrinology & Metabolism

Year:

2009

Language:

english

File:

PDF, 330 KB

english, 2009

16

Aging Reduces Proliferative Capacities of Liver by Switching Pathways of C/EBPα Growth Arrest

Polina Iakova, Samir S Awad, Nikolai A Timchenko

Journal:

Year:

2003

Language:

english

File:

PDF, 606 KB

english, 2003

17

C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4

Hongmei Wang, Polina Iakova, Margie Wilde, Alana Welm, Triona Goode, William J Roesler, Nikolai A Timchenko

Journal:

Year:

2001

Language:

english

File:

PDF, 601 KB

english, 2001

18

Expression of RNA CCUG Repeats Dysregulates Translation and Degradation of Proteins in Myotonic Dystrophy 2 Patients

Elizabeth Salisbury, Benedikt Schoser, Christiane Schneider-Gold, Guo-Li Wang, Claudia Huichalaf, Bingwen Jin, Mario Sirito, Partha Sarkar, Ralf Krahe, Nikolai A. Timchenko, Lubov T. Timchenko

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 2.67 MB

english, 2009

19

SKI knockdown inhibits human melanoma tumor growth in vivo

Dahu Chen, Qiushi Lin, Neil Box, Dennis Roop, Shunsuke Ishii, Koichi Matsuzaki, Tao Fan, Thomas J. Hornyak, Jon A Reed, Ed Stavnezer, Nikolai A. Timchenko, Estela E. Medrano

Journal:

Pigment Cell & Melanoma Research

Year:

2009

Language:

english

File:

PDF, 753 KB

english, 2009

20

The role of CUGBP1 in age-dependent changes of liver functions

Karlie Jones, Lubov Timchenko, Nikolai A. Timchenko

Journal:

Ageing Research Reviews

Year:

2012

Language:

english

File:

PDF, 632 KB

english, 2012

21

Regulation of apoptotic and growth inhibitory activities of C/EBPα in different cell lines

Guo-Li Wang, Xiurong Shi, Elizabeth Salisbury, Nikolai A. Timchenko

Journal:

Experimental Cell Research

Year:

2008

Language:

english

File:

PDF, 1.77 MB

english, 2008

22

Dynamic regulation of the human dopachrome tautomerase promoter by MITF, ER-α and chromatin remodelers during proliferation and senescence of human melanocytes

Denise J. Schwahn, Nikolai A. Timchenko, Shigeki Shibahara, Estela E. Medrano

Journal:

Pigment Cell & Melanoma Research

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

23

Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer

Jiang, Yanjun, Iakova, Polina, Jin, Jingling, Sullivan, Emily, Sharin, Vladislav, Hong, Il-Hwa, Anakk, Sayee, Mayor, Angela, Darlington, Gretchen, Finegold, Milton, Moore, David, Timchenko, Nikolai A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

24

Increased Expression of Enzymes of Triglyceride Synthesis Is Essential for the Development of Hepatic Steatosis

Jin, Jingling, Iakova, Polina, Breaux, Meghan, Sullivan, Emily, Jawanmardi, Nicole, Chen, Dahu, Jiang, Yanjun, Medrano, Estela M., Timchenko, Nikolai A.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.17 MB

english, 2013

25

Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice

Jiang, Yanjun, Jin, Jingling, Iakova, Polina, Hernandez, Julio Cesar, Jawanmardi, Nicole, Sullivan, Emily, Guo, Grace L., Timchenko, Nikolai A., Darlington, Gretchen J.

Journal:

Mechanisms of Ageing and Development

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

26

Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration

Jin, Jingling, Hong, Il-Hwa, Lewis, Kyle, Iakova, Polina, Breaux, Meghan, Jiang, Yanjun, Sullivan, Emily, Jawanmardi, Nicole, Timchenko, Lubov, Timchenko, Nikolai A.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

27

GSK3β is a new therapeutic target for myotonic dystrophy type 1

Wei, Christina, Jones, Karlie, Timchenko, Nikolai A, Timchenko, Lubov

Journal:

Year:

2013

Language:

english

File:

PDF, 471 KB

english, 2013

28

p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways

Breaux, Meghan, Lewis, Kyle, Valanejad, Leila, Iakova, Polina, Chen, Fengju, Mo, Qianxing, Medrano, Estela, Timchenko, Lubov, Timchenko, Nikolai

Journal:

Molecular and Cellular Biology

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

29

The Glutamine-Alanine Repeat Domain of TCERG1 is Required for the Inhibition of the Growth Arrest Activity of C/EBPα

Miller, Nicholas J., Schick, Kaitlyn, Timchenko, Nikolai, Harrison, Emmett, Roesler, William J.

Journal:

Journal of Cellular Biochemistry

Year:

2015

File:

PDF, 697 KB

2015

30

The Glutamine-Alanine Repeat Domain of TCERG1 is Required for the Inhibition of the Growth Arrest Activity of C/EBPα

Miller, Nicholas J., Schick, Kaitlyn, Timchenko, Nikolai, Harrison, Emmett, Roesler, William J.

Journal:

Journal of Cellular Biochemistry

Year:

2015

Language:

english

File:

PDF, 697 KB

english, 2015

31

Reduction of toxic RNAs in myotonic dystrophies type 1 and type 2 by the RNA helicase p68/DDX5

Jones, Karlie, Wei, Christina, Schoser, Benedikt, Meola, Giovanni, Timchenko, Nikolai, Timchenko, Lubov

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

32

SKI promotes Smad3 linker phosphorylations associated with the tumor-promoting trait of TGF-β

Lin, Qiushi, Chen, Dahu, Timchenko, Nikolai A., Medrano, Estela E.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

33

Old Livers: C/EBPa Meets New Partners

Timchenko, Nikolai A.

Journal:

Year:

2003

Language:

english

File:

PDF, 61 KB

english, 2003

34

GSK3β-cyclin D3-CUGBP1-eIF2 pathway in aging and in Myotonic Dystrophy

Jin, Jingling, Wang, Guo-Li, Salisbury, Elizabeth, Timchenko, Lubov, Timchenko, Nikolai A.

Journal:

Year:

2009

File:

PDF, 851 KB

2009

35

GSK3β-cyclin D3-CUGBP1-eIF2 pathway in aging and in Myotonic Dystrophy

Jin, Jingling, Wang, Guo-Li, Salisbury, Elizabeth, Timchenko, Lubov, Timchenko, Nikolai A.

Journal:

Year:

2009

Language:

english

File:

PDF, 851 KB

english, 2009

36

Cell-type specific functions of epidermal growth factor receptor are involved in development of hepatocellular carcinoma

Timchenko, Nikolai A.

Journal:

Year:

2015

Language:

english

File:

PDF, 680 KB

english, 2015

37

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

Timchenko, Nikolai A., Wilde, Margie, Darlington, Gretchen J.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 3.82 MB

english, 1999

38

Akt-FoxO1 axis controls liver regeneration

Valanejad, Leila, Timchenko, Nikolai

Journal:

Year:

2016

Language:

english

File:

PDF, 111 KB

english, 2016

39

Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease

Jin, Jingling, Valanejad, Leila, Nguyen, Thuy Phuong, Lewis, Kyle, Wright, Mary, Cast, Ashley, Stock, Lauren, Timchenko, Lubov, Timchenko, Nikolai A.

Journal:

Year:

2016

Language:

english

File:

PDF, 6.05 MB

english, 2016

40

C/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage

Welm, Alana L., Timchenko, Nikolai A., Darlington, Gretchen J.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.29 MB

english, 1999

41

SPIE Proceedings [SPIE Microlithography '99 - Santa Clara, CA (Sunday 14 March 1999)] Emerging Lithographic Technologies III - Self-supporting tantalum masks for deep x-ray lithography with synchrotron radiation

Litvin, Sergey V., Vladimirsky, Yuli, Kanaev, Vasily G., Larionova, Elena G., Glazunova, Nina V., Gromova, Ludmila P., Yurchenko, Vasily I., Timchenko, Nikolai A., Mezentseva, Lubov A., Nazmov, Vladim

Year:

1999

Language:

english

File:

PDF, 1.46 MB

english, 1999

42

Generation of pediatric liver cancer patient-derived xenograft platforms for pediatric liver cancer: A critical stage in the development of anticancer treatments

Tiao, Gregory, Geller, James, Timchenko, Nikolai A.

Journal:

Year:

2016

Language:

english

File:

PDF, 147 KB

english, 2016

43

RNA binding protein CUGBP1 inhibits liver cancer in a phosphorylation dependent manner

Lewis, Kyle, Valanejad, Leila, Cast, Ashley, Wright, Mary, Wei, Christina, Iakova, Polina, Stock, Lauren, Karns, Rebekah, Timchenko, Lubov, Timchenko, Nikolai

Journal:

Molecular and Cellular Biology

Year:

2017

Language:

english

File:

PDF, 8.29 MB

english, 2017

44

Mitochondrial and anabolic pathways in hepatocellular carcinoma

Timchenko, Nikolai A.

Journal:

Year:

2017

Language:

english

File:

PDF, 588 KB

english, 2017

45

Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/DGAT1 pathway

Guillory, Bobby, Jawanmardi, Nicole, Iakova, Polina, Anderson, Barbara, Zang, Pu, Timchenko, Nikolai A., Garcia, Jose M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

46

Intravenous miR-144 inhibits tumor growth in diethylnitrosamine-induced hepatocellular carcinoma in mice

He, Quan, Wang, Fangfei, Honda, Takashi, Lindquist, Diana M, Dillman, Jonathan R, Timchenko, Nikolai A, Redington, Andrew N

Journal:

Year:

2017

Language:

english

File:

PDF, 913 KB

english, 2017

47

C/EBPα-dependent pre-neoplastic tumor foci are the origin of hepatocellular carcinoma and aggressive pediatric liver cancer

Cast, Ashley, Valanejad, Leila, Wright, Mary, Nguyen, Phuong, Gupta, Anita, Zhu, Liqin, Shin, Soona, Timchenko, Nikolai

Journal:

Year:

2017

Language:

english

File:

PDF, 2.13 MB

english, 2017

48

Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1

Wei, Christina, Stock, Lauren, Valanejad, Leila, Zalewski, Zachary A., Karns, Rebekah, Puymirat, Jack, Nelson, David, Witte, David, Woodgett, Jim, Timchenko, Nikolai A., Timchenko, Lubov

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 3.37 MB

english, 2017

49

Reduction of Cellular Nucleic Acid Binding Protein encoded by a Myotonic Dystrophy type 2 gene causes muscle atrophy

Wei, Christina, Stock, Lauren, Schneider-Gold, Christiane, Sommer, Claudia, Timchenko, Nikolai A., Timchenko, Lubov

Journal:

Molecular and Cellular Biology

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

50

PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma

Valanejad, Leila, Cast, Ashley, Wright, Mary, Bissig, Karl-Dimiter, Karns, Rebekah, Weirauch, Matthew T., Timchenko, Nikolai

Journal:

Communications Biology

Year:

2018

Language:

english

File:

PDF, 2.51 MB

english, 2018