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51

The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes

Martin E. M. Noble, Rik K. Wierenga, Anne-Marie Lambeir, Fred R. Opperdoes, Andy-Mark W. H. Thunnissen, Kor H. Kalk, Hillie Groendijk, Wim G. J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 1.63 MB

english, 1991

52

Structures of the “open” and “closed” state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: Implications for the reaction mechanism

Martin E. M. Noble, Johan Ph. Zeelen, Dr. Rik K. Wierenga

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1993

Language:

english

File:

PDF, 1.33 MB

english, 1993

53

An heuristic algorithm for short term irrigation scheduling using hosereel-raingun systems

Martin J. Upcraft, David H. Noble, Michael K. V. Carr

Journal:

Irrigation Science

Year:

1996

Language:

english

File:

PDF, 735 KB

english, 1996

54

RNA and protein-dependent mechanisms in tauopathies: consequences for therapeutic strategies

J.-M. Gallo, W. Noble, T. Rodriguez Martin

Journal:

Cellular and Molecular Life Sciences

Year:

2007

Language:

english

File:

PDF, 360 KB

english, 2007

55

Addressing issues associated with the development and management of PT programs and with their optimum use

Jean Claude Libeer, Harold Richardson, David Bullock, Claus Heuck, D. Tholen, Robert Martin, Jane Carter, E. J. Boone, M. Noble

Journal:

Accreditation and Quality Assurance

Year:

2002

Language:

english

File:

PDF, 82 KB

english, 2002

56

Behavioural indicators of welfare in farmed fish

Catarina I. M. Martins, Leonor Galhardo, Chris Noble, Børge Damsgård, Maria T. Spedicato, Walter Zupa, Marilyn Beauchaud, Ewa Kulczykowska, Jean-Charles Massabuau, Toby Carter, Sònia Rey Planellas, To

Journal:

Fish Physiology and Biochemistry

Year:

2012

Language:

english

File:

PDF, 368 KB

english, 2012

57

Probing the architecture of theMycobacterium marinumarylamine N-acetyltransferase active site

Areej M. Abuhammad, Edward D. Lowe, Elizabeth Fullam, Martin Noble, Elspeth F. Garman, Edith Sim

Journal:

Year:

2010

Language:

english

File:

PDF, 350 KB

english, 2010

58

Response of superheated droplet detectors of the PICASSO dark matter search experiment

M. Barnabé-Heider, M. Di Marco, P. Doane, M.-H. Genest, R. Gornea, R. Guénette, C. Leroy, L. Lessard, J.-P. Martin, U. Wichoski, V. Zacek, K. Clark, C.B. Krauss, A.J. Noble, E. Behnke, W. Feighery, I.

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2005

Language:

english

File:

PDF, 747 KB

english, 2005

59

Volatile agent use

D.W. Noble, L.V.H. Martin

Journal:

Year:

1990

Language:

english

File:

PDF, 89 KB

english, 1990

60

A simple method of magnetic declination fluctuation correction for long single-streamer positioning in a seismic survey

Victor Martin, Mark S. Noble, Georges Pascal

Journal:

Geophysical Prospecting

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

61

The effect of professional skills training on patient-centredness and confidence in communicating with patients

Lorraine M Noble, Angela Kubacki, Jonathan Martin, Margaret Lloyd

Journal:

Medical Education

Year:

2007

Language:

english

File:

PDF, 492 KB

english, 2007

62

A survey and audit of the first ‘Guides to Local Health Services’ produced by Primary Care Trusts in England

Jenny Noble, Mark Hann, Rod Sheaff, Martin Marshall

Journal:

Health Expectations

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

63

Development of an information source for patients and the public about general practice services: an action research study

Martin Marshall, Jenny Noble, Helen Davies, Heather Waterman, Kieran Walshe, Rod Sheaff, Glyn Elwyn

Journal:

Health Expectations

Year:

2006

Language:

english

File:

PDF, 513 KB

english, 2006

64

Retrospective analysis of patients attending a neurofibromatosis type 1 clinic

Fiona Noble, Andrew J Kornberg, James E Elder, Martin B Delatycki

Journal:

Journal of Paediatrics and Child Health

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

65

Pharmacodynamic Effects in the Cardiovascular System: The Modeller’s View

Martin Fink, Denis Noble

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

66

Understanding Small-Molecule Binding to MDM2: Insights into Structural Effects of Isoindolinone Inhibitors from NMR Spectroscopy

Christiane Riedinger, Martin E. Noble, David J. Wright, Florian Mulks, Ian R. Hardcastle, Jane A. Endicott, James M. McDonnell

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

67

10.1038/15674

Johnson, Louise N., Brown, Nick R., Noble, Martin E. M., Endicott, Jane A.

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 1.14 MB

english, 1999

68

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

Raff, Martin C., Miller, Robert H., Noble, Mark

Journal:

Year:

1983

File:

PDF, 1.02 MB

1983

69

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

Raff, Martin C., Lillien, Laura E., Richardson, William D., Burne, Julia F., Noble, Mark D.

Journal:

Year:

1988

File:

PDF, 496 KB

1988

70

Crystal structure of a Src-homology 3 (SH3) domain

Musacchio, Andrea, Noble, Martin, Pauptit, Richard, Wierenga, Rik, Saraste, Matti

Journal:

Year:

1992

File:

PDF, 700 KB

1992

71

10.1038/76783

Noble, Martin E.M., Sinclair, John C., Sandy, James, Delgoda, Rupika, Sim, Edith

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 807 KB

english, 2000

72

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

Lawrie, Alison M., Noble, Martin E.M., Tunnah, Paul, Brown, Nicholas R., Johnson, Louise N., Endicott, Jane A.

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 1013 KB

1997

73

Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

Noble, Christian G, Hollingworth, David, Martin, Stephen R, Ennis-Adeniran, Valerie, Smerdon, Stephen J, Kelly, Geoff, Taylor, Ian A, Ramos, Andres

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 463 KB

english, 2005

74

Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain

Trempe, Jean-François, Brown, Nicholas R, Lowe, Edward D, Gordon, Colin, Campbell, Iain D, Noble, Martin E M, Endicott, Jane A

Journal:

The EMBO Journal

Year:

2005

Language:

english

File:

PDF, 415 KB

english, 2005

75

Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease

Bilbao, J R, Calvo, B, Aransay, A M, Martin-Pagola, A, Perez de Nanclares, G, Aly, T A, Rica, I, Vitoria, J C, Gaztambide, S, Noble, J

Journal:

Genes and Immunity

Year:

2006

Language:

english

File:

PDF, 375 KB

english, 2006

76

Replacing the (Î²Î±)-unit 8 of E.coli TIM with its chicken homologue leads to a stable and active hybrid enzyme

Mainfroid, Véronique, Goraj, Karine, Rentier-Delrue, Francoise, Houbrechts, Annick, Noble, Martin E.M., Borchert, Torben V., Wierenga, Rik K., Martial, Joseph A.

Journal:

Protein Engineering Design and Selection

Year:

1993

Language:

english

File:

PDF, 2.13 MB

english, 1993

77

Enantiospecific synthesis of 3?-hetero-dideoxy nucleoside analogues as potential anti-HIV agents

Jones, Martin F., Noble, Stewart A., Robertson, Colin A., Storer, Richard, Highcock, Rona M., Lamont, R. Brian

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1992

Language:

english

File:

PDF, 1.42 MB

english, 1992

78

Specificity Determinants of Recruitment Peptides Bound to Phospho-CDK2/Cyclin A†,‡

Lowe, Edward D., Tews, Ivo, Cheng, Kin Yip, Brown, Nick R., Gul, Sheraz, Noble, Martin E. M., Gamblin, Steven J., Johnson, Louise N.

Journal:

Year:

2002

Language:

english

File:

PDF, 612 KB

english, 2002

79

Aloisines, a New Family of CDK/GSK-3 Inhibitors. SAR Study, Crystal Structure in Complex with CDK2, Enzyme Selectivity, and Cellular Effects

Mettey, Yvette, Gompel, Marie, Thomas, Virginie, Garnier, Matthieu, Leost, Maryse, Ceballos-Picot, Irène, Noble, Martin, Endicott, Jane, Vierfond, Jean-michel, Meijer, Laurent

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 658 KB

english, 2003

80

Toward application of conformal decomposition finite elements to non-colloidal particle suspensions

Jeremy B. Lechman, Martin B. Nemer, David R. Noble

Journal:

International Journal for Numerical Methods in Fluids

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

81

Treatment of Uterine Leiomyosarcoma in a Xenograft Nude Mouse Model Using High-Intensity Focused Ultrasound: A Potential Treatment Modality for Recurrent Pelvic Disease

Amid Keshavarzi, Shahram Vaezy, Misty L. Noble, Emil Y. Chi, Cheryl Walker, Roy W. Martin, Victor Y. Fujimoto

Journal:

Gynecologic Oncology

Year:

2002

Language:

english

File:

PDF, 207 KB

english, 2002

82

Endothelin-mediated induction of heme oxygenase-1 in the spinal cord is attenuated in transgenic mice overexpressing superoxide dismutase

Martin Weinzierl, A.E. Mautes, William Whetstone, Yong Lin, Linda J. Noble-Haeusslein

Journal:

Year:

2004

Language:

english

File:

PDF, 449 KB

english, 2004

83

Contributions of HERG current to repolarization of the human ventricular action potential

Martin Fink, Denis Noble, Laszlo Virag, Andras Varro, Wayne R. Giles

Journal:

Progress in Biophysics and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.66 MB

english, 2008

84

Catalysis and regulation

Martin Noble, John S Blanchard

Journal:

Current Opinion in Structural Biology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

85

Catalysis and regulation

Martin Noble, John E Ladbury

Journal:

Current Opinion in Structural Biology

Year:

2011

Language:

english

File:

PDF, 141 KB

english, 2011

86

Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain

Maria K. Hoellerer, Martin E.M. Noble, Gilles Labesse, Iain D. Campbell, Jörn M. Werner, Stefan T. Arold

Journal:

Year:

2003

Language:

english

File:

PDF, 682 KB

english, 2003

87

Structures of P. falciparum PfPK5 Test the CDK Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition

Simon Holton, Anais Merckx, Darren Burgess, Christian Doerig, Martin Noble, Jane Endicott

Journal:

Year:

2003

Language:

english

File:

PDF, 456 KB

english, 2003

88

Structures of P. falciparum Protein Kinase 7 Identify an Activation Motif and Leads for Inhibitor Design

Anais Merckx, Aude Echalier, Kia Langford, Audrey Sicard, Gordon Langsley, Jos Joore, Christian Doerig, Martin Noble, Jane Endicott

Journal:

Year:

2008

Language:

english

File:

PDF, 1.39 MB

english, 2008

89

Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin

Sonja Lorenz, Ioannis Vakonakis, Edward D. Lowe, Iain D. Campbell, Martin E.M. Noble, Maria K. Hoellerer

Journal:

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

90

Fast food and fat fillies: The ills of western civilisation

Martin Sillence, Glenys Noble, Catherine McGowan

Journal:

The Veterinary Journal

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

91

Potential treatments for insulin resistance in the horse: A comparative multi-species review

Kellie D. Tinworth, Patricia A. Harris, Martin N. Sillence, Glenys K. Noble

Journal:

The Veterinary Journal

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

92

The effect of oral metformin on insulin sensitivity in insulin-resistant ponies

Kellie D. Tinworth, Ray C. Boston, Patricia A. Harris, Martin N. Sillence, Sharanne L. Raidal, Glenys K. Noble

Journal:

The Veterinary Journal

Year:

2012

Language:

english

File:

PDF, 314 KB

english, 2012

93

Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2

Louise N. Johnson, Erika De Moliner, Nick R. Brown, Haiwei Song, David Barford, Jane A. Endicott, Martin E.M. Noble

Journal:

Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 695 KB

english, 2002

94

Structure-based design of cyclin-dependent kinase inhibitors

Thomas G. Davies, David J. Pratt, Jane A. Endicott, Louise N. Johnson, Martin E.M. Noble

Journal:

Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

95

Chemical Inhibitors of Cyclin-Dependent Kinases: Insights into Design from X-Ray Crystallographic Studies

Martin E.M Noble, Jane A Endicott

Journal:

Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 1.81 MB

english, 1999

96

Cyclin-dependent kinases: inhibition and substrate recognition

Jane A Endicott, Martin EM Noble, Julie A Tucker

Journal:

Current Opinion in Structural Biology

Year:

1999

Language:

english

File:

PDF, 685 KB

english, 1999

97

The cyclin box fold: protein recognition in cell-cycle and transcription control

Martin E.M. Noble, Jane A. Endicott, Nick R. Brown, Louise N. Johnson

Journal:

Trends in Biochemical Sciences

Year:

1997

Language:

english

File:

PDF, 1.46 MB

english, 1997

98

Inhibitor Binding to Active and Inactive CDK2: The Crystal Structure of CDK2-Cyclin A/Indirubin-5-Sulphonate

Thomas G. Davies, Paul Tunnah, Laurent Meijer, Doris Marko, Gerhard Eisenbrand, Jane A. Endicott, Martin E.M. Noble

Journal:

Year:

2001

Language:

english

File:

PDF, 714 KB

english, 2001

99

The Structural Basis of Localization and Signaling by the Focal Adhesion Targeting Domain

Stefan T Arold, Maria K Hoellerer, Martin E.M Noble

Journal:

Year:

2002

Language:

english

File:

PDF, 357 KB

english, 2002

100

Structural principles in cell-cycle control: beyond the CDKs

Jane A Endicott, Martin EM Noble

Journal:

Year:

1998

Language:

english

File:

PDF, 170 KB

english, 1998

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