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51

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

Carreira, S., Goodall, J., Denat, L., Rodriguez, M., Nuciforo, P., Hoek, K. S., Testori, A., Larue, L., Goding, C. R.

Journal:

Genes & Development

Year:

2006

Language:

english

File:

PDF, 991 KB

english, 2006

52

Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression

Nuciforo, P. G., Luise, C., Capra, M., Pelosi, G., d'Adda di Fagagna, F.

Journal:

Year:

2007

Language:

english

File:

PDF, 725 KB

english, 2007

53

Benefit to neoadjuvant anti-human epidermal growth factor receptor 2 (HER2)-targeted therapies in HER2-positive primary breast cancer is independent of phosphatase and tensin homolog deleted from chromosome 10 (PTEN) status

Nuciforo, P. G., Aura, C., Holmes, E., Prudkin, L., Jimenez, J., Martinez, P., Ameels, H., de la Pena, L., Ellis, C., Eidtmann, H., Piccart-Gebhart, M. J., Scaltriti, M., Baselga, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 707 KB

english, 2015

54

Quantification of HER family receptors in breast cancer

Nuciforo, Paolo, Radosevic-Robin, Nina, Ng, Tony, Scaltriti, Maurizio

Journal:

Breast Cancer Research

Year:

2015

Language:

english

File:

PDF, 471 KB

english, 2015

55

Monoclonal Antibodies against the Human Somatostatin Receptor Subtypes 15: Development and Immunohistochemical Application in Neuroendocrine Tumors

Schmid, Herbert A., Lambertini, Chiara, van Vugt, Harmke H., Barzaghi-Rinaudo, Patrizia, Schäfer, Judith, Hillenbrand, Rainer, Sailer, Andreas W., Kaufmann, Martina, Nuciforo, Paolo

Journal:

Neuroendocrinology

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

56

Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions

Raynaud, C. M., Jang, S. J., Nuciforo, P., Lantuejoul, S., Brambilla, E., Mounier, N., Olaussen, K. A., Andre, F., Morat, L., Sabatier, L., Soria, J.-C.

Journal:

Annals of Oncology

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008

57

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

Goodall, J., Carreira, S., Denat, L., Kobi, D., Davidson, I., Nuciforo, P., Sturm, R. A., Larue, L., Goding, C. R.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 609 KB

english, 2008

58

Clinical Response to a Lapatinib-Based Therapy for a Li-Fraumeni Syndrome Patient with a Novel HER2V659E Mutation

Serra, V., Vivancos, A., Puente, X. S., Felip, E., Silberschmidt, D., Caratu, G., Parra, J.-L., De Mattos-Arruda, L., Grueso, J., Hernandez-Losa, J., Arribas, J., Prudkin, L., Nuciforo, P., Scaltriti,

Journal:

Cancer Discovery

Year:

2013

Language:

english

File:

PDF, 3.24 MB

english, 2013

59

Lymphomas of the Bone: A Pathological and Clinical Study of 54 Cases

Gianelli, U., Patriarca, C., Moro, A., Ponzoni, M., Giardini, R., Massimino, M., Alfano, R. M., Armiraglio, E., Nuciforo, P., Bosari, S., Coggi, G., Parafioriti, A.

Journal:

International Journal of Surgical Pathology

Year:

2002

Language:

english

File:

PDF, 2.41 MB

english, 2002

60

Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes

Herrero, Ana, Pinto, Adán, Colón-Bolea, Paula, Casar, Berta, Jones, Mary, Agudo-Ibáñez, Lorena, Vidal, Rebeca, Tenbaum, Stephan P., Nuciforo, Paolo, Valdizán, Elsa M., Horvath, Zoltan, Orfi, Laszlo, P

Journal:

Year:

2015

Language:

english

File:

PDF, 3.79 MB

english, 2015

61

MEK plus PI3K/mTORC1/2 therapeutic efficacy is impacted by TP53 mutation in preclinical models of colorectal cancer

Celina, G.-G., Rivas, M. A., Ibrahim, Y. H., Calvo, M. T., Gris-Oliver, A., Rodriguez, O., Grueso, J., Anton, P., Guzman, M., Aura, C., Nuciforo, P., Jessen, K., Argiles, G., Dienstmann, R., Bertotti,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

62

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab

Salgado, Roberto, Denkert, Carsten, Campbell, Christine, Savas, Peter, Nuciforo, Paolo, Aura, Claudia, de Azambuja, Evandro, Eidtmann, Holger, Ellis, Catherine E., Baselga, Jose, Piccart-Gebhart, Mart

Journal:

Year:

2015

Language:

english

File:

PDF, 356 KB

english, 2015

63

Prediction of Response to Neoadjuvant Chemotherapy Using Core Needle Biopsy Samples with the Prosigna Assay

Prat, A., Galvan, P., Jimenez, B., Buckingham, W., Jeiranian, H. A., Schaper, C., Vidal, M., Alvarez, M., Diaz, S., Ellis, C., Nuciforo, P., Ferree, S., Ribelles, N., Adamo, B., Ramon y Cajal, S., Peg

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 333 KB

english, 2015

64

High HER2 protein levels correlate with increased survival in breast cancer patients treated with anti-HER2 therapy

Nuciforo, Paolo, Thyparambil, Sheeno, Aura, Claudia, Garrido-Castro, Ana, Vilaro, Marta, Peg, Vicente, Jimenez, José, Vicario, Rocio, Cecchi, Fabiola, Hoos, William, Burrows, Jon, Hembrough, Todd, Fer

Journal:

Molecular Oncology

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

65

In reply

Nuciforo, Paolo Giovanni, O’Hara, Carolyn Dawn, Bonetti, Franco, Martignoni, Guido, Pea, Maurizio, Tazelaar, Henry D., Batts, Kenneth P., Srigley, John R.

Journal:

Modern Pathology

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

66

Russian folk discourse on problem drinking

Nuciforo, Elena V.

Journal:

Russian Journal of Communication

Year:

2015

Language:

english

File:

PDF, 323 KB

english, 2015

67

301 First-in-human phase I dose-escalation study of a MET/AXL/FGFR inhibitor, S 49076, in patients with advanced solid tumors

Azaro, A., Rodon, J., Herranz, M., Nuciforo, P., Prudkin, L., Lopez-Busto, N., Balandraud, S., Cattan, V., Jacquet-Bescond, A., Marfai, L., Pauly, J., Postel-Vinay, S., Hollebecque, A., Soria, J.C.

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

68

2399 Impact of KRAS mutations on clinical outcomes in advanced refractory pancreatic cancer patients

Sauri, T., Macarulla, T., Sanz-Garcia, E., Moreno, D., Vilaro, M., Vivancos, A., Elez, E., Argil és, G., Grasselli, J., Capdevila, J., Alsina, M., Hierro, C., Matos, I., Dientsmann, R., Nuciforo, P.,

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

69

Five-day Triple Therapy in Helicobacter pylori-positive Duodenal Ulcer

Catalano, F., Catanzaro, R., Branciforte, G., Bentivegna, C., Cipolla, R., Brogna, A., Nuciforo, G.

Journal:

Journal of Clinical Gastroenterology

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

70

Fam60A plays a role for production stabilities of recombinant CHO cell lines

Ritter, Anett, Nuciforo, Sandro, Schulze, Axel, Oertli, Mevion, Rauschert, Tatjana, Voedisch, Bernd, Geisse, Sabine, Jostock, Thomas, Laux, Holger

Journal:

Biotechnology and Bioengineering

Year:

2016

Language:

english

File:

PDF, 456 KB

english, 2016

71

Pathway level alterations rather than mutations in single genes predict response to HER2 targeted therapies in the neo-ALTTO trial

Shi, W., Jiang, T., Nuciforo, P., Hatzis, C., Holmes, E., Harbeck, N., Sotiriou, C., Peña, L., Loi, S., Rosa, D. D., Chia, S., Wardley, A., Ueno, T., Rossari, J., Eidtmann, H., Armour, A., Piccart-Geb

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 777 KB

english, 2016

72

PI3K blockade reverses primary resistance and adaptation to eribulin in PI3K-pathway activated breast cancer tumors

Gris-Oliver, A., Saura, C., Oliveira, M., Piris, A., Nuciforo, P., Pérez-García, J., Arribas, J., Baselga, J., Cortés, J., Serra, V.

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 60 KB

english, 2016

73

ERRATUM: Genomic Analyses across Six Cancer Types Identify Basal-like Breast Cancer as a Unique Molecular Entity

Prat, Aleix, Adamo, Barbara, Fan, Cheng, Peg, Vicente, Vidal, Maria, Galván, Patricia, Vivancos, Ana, Nuciforo, Paolo, Palmer, Héctor G., Dawood, Shaheenah, Rodón, Jordi, Cajal, Santiago Ramon y, Camp

Journal:

Scientific Reports

Year:

2015

File:

PDF, 138 KB

2015

74

The search for simplicity: is this compatible with precision medicine?

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 105 KB

english, 2016

75

Lack of RAD51 foci formation enables the identification of PARP inhibitor sensitive breast tumors

Castroviejo-Bermejo, M., Cruz, C., Guerra, S., Llop-Guevara, A., Gutiérrez-Enríquez, S., Bruna, A., Rubio, I.T., Oakin, A., Nucíforo, P., Díez, O., Arribas, J., Judde, J.G., Caldas, C., Baselga, J., C

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 62 KB

english, 2016

76

HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, single-group, multicentre, phase 2 trial

Llombart-Cussac, Antonio, Cortés, Javier, Paré, Laia, Galván, Patricia, Bermejo, Begoña, Martínez, Noelia, Vidal, Maria, Pernas, Sònia, López, Rafael, Muñoz, Montserrat, Nuciforo, Paolo, Morales, Sera

Journal:

The Lancet Oncology

Year:

2017

Language:

english

File:

PDF, 295 KB

english, 2017

77

Molecular, clinical and prognostic characterization of double KRAS/PIK3CA (dKP) mutated metastatic colorectal cancer (mCRC)

Grasselli, J., Elez, E., Martinez, G. Argiles, Sanz-Garcia, E., Macarulla, T., Capdevila, J., Alsina, M., Sauri, T., Hierro, C., Verdaguer, H., Matos, I., Garcia, A., Nuciforo, P., Landolfi, S., Palme

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 37 KB

english, 2016

78

Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer.

Grasselli, J., Elez, E., Caratù, G., Matito, J., Santos, C., Macarulla, T., Vidal, J., Garcia, M., Viéitez, J.M., Paéz, D., Falcó, E., Lopez Lopez, C., Aranda, E., Jones, F., Sikri, V., Nuciforo, P.,

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

79

Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup

Ieni, Antonio, Barresi, Valeria, Licata, Luana, Cardia, Roberta, Fazzari, Carmine, Nuciforo, Giuseppe, Caruso, Francesco, Caruso, Michele, Adamo, Vincenzo, Tuccari, Giovanni

Journal:

Oncology Letters

Year:

2017

Language:

english

File:

PDF, 785 KB

english, 2017

80

Immune-related gene expression profiling after PD-1 blockade in non-small cell lung carcinoma, head and neck squamous cell carcinoma and melanoma.

Prat, Aleix, Navarro, Alejandro, Paré, Laia, Reguart, Noemí, Galvan, Patricia, Pascual, Tomás, Martínez, Alex, Nuciforo, Paolo, Comerma, Laura, Alos, Llucia, Pardo, Nuria, Cedrés, Susana, Fan, Cheng,

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

81

First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours

Rodon, Jordi, Postel-Vinay, Sophie, Hollebecque, Antoine, Nuciforo, Paolo, Azaro, Analia, Cattan, Valérie, Marfai, Lucie, Sudey, Isabelle, Brendel, Karl, Delmas, Audrey, Malasse, Stéphanie, Soria, Jea

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

82

A predictive model of pathological response based on tumor cellularity and tumor-infiltrating lymphocytes (CelTIL) in HER2-positive breast cancer treated with chemo-free dual HER2 blockade

Nuciforo, P, Pascual, T, Cortés, J, Llombart-Cussac, A, Fasani, R, Paré, L, Oliveira, M, Galvan, P, Martínez, N, Bermejo, B, Vidal, M, Pernas, S, López, R, Muñoz, M, Garau, I, Manso, L, Alarcón, J, Ma

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

83

155PDTumor-infiltrating lymphocytes (TILs) in HER2-positive (HER2+) early breast cancer treated with neoadjuvant lapatinib and trastuzumab without chemotherapy in the PAMELA Trial

Nuciforo, P., Prat, A., Llombart, A., Fasani, R., Paré, L., Pascual, T., Oliveira, M., Martínez Jañez, N., Bermejo De Las Heras, B., Vidal, M., Pernas Simon, S., López, R., Muñoz, M., Garau, I., Manso

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

84

Tumor-infiltrating lymphocytes density correlates with HER2 gene copy number but not with protein levels in HER2-positive breast cancer

Fasani, R., Comerma, L., Pagliuca, F., Thyparambil, S., Peg, V., Jimenez, J., Cecchi, F., Hembrough, T., Perez, J., Arribas, J., Cortes, J., Scaltriti, M., Saura, C., Nuciforo, P.

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 51 KB

english, 2018

85

Early evolutionary divergence between papillary and anaplastic thyroid cancers

Capdevila, J, Mayor, R, Mancuso, F F, Iglesias, C, Caratù, G, Matos, I, Zafón, C, Hernando, J, Petit, A, Nuciforo, P, Cameselle-Teijeiro, J M, Álvarez, C, Recio, J A, Tabernero, J, Matias-Guiu, X, Viv

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 800 KB

english, 2018

86

430ODifferent RNA expression profile defines prognosis in grade 1/2 neuroendocrine neoplasms of small intestine origin: The GETNE-NETSEQ study

Capdevila, J., Mancuso, F., Landolfi, S., Salva, F., Miguel, C., Jiménez-Fonseca, P., Garcia-Carbonero, R., López López, C., Casteras, A., Sauri Nadal, T., Nuciforo, P., Vivancos, A., Matos, I.

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 52 KB

english, 2017

87

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle

Mattos-Arruda, L De, Weigelt, B, Cortes, J, Won, H H, Ng, C K Y, Nuciforo, P, Bidard, F-C, Aura, C, Saura, C, Peg, V, Piscuoglio, S, Oliveira, M, Smolders, Y, Patel, P, Norton, L, Tabernero, J, Berger

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 41 KB

english, 2018

88

Analysis of mismatch repair (MMR) genes and pd-l1 expression in invasive micropapillary carcinoma of the breast (IMPCS)

Simonetti, S., Dominguez, N., Pepe, F., Nacchio, M., Conticelli, F., Malapelle, U., Sanchez, L., Guardia, X., Insabato, L., Nuciforo, P., Carrasco, M.A.

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 61 KB

english, 2018

89

Degradation of recombinant proteins by CHO host cell proteases is prevented by Matriptase-1 knock-out

Laux, Holger, Romand, Sandrine, Nuciforo, Sandro, Farady, Christopher J., Tapparel, Joel, Buechmann-Moeller, Stine, Sommer, Benjamin, Oakeley, Edward J., Bodendorf, Ursula

Journal:

Biotechnology and Bioengineering

Year:

2018

Language:

english

File:

PDF, 596 KB

english, 2018

90

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells

Calabrese, D., Roma, G., Bergling, S., Carbone, W., Mele, V., Nuciforo, S., Fofana, I., Campana, B., Szkolnicka, D., Hay, D., Tchorz, J., Bouwmeester, T., Wieland, S., Heim, M.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 51 KB

english, 2018

91

Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies

Saei, Azad, Palafox, Marta, Benoukraf, Touati, Kumari, Nishi, Jaynes, Patrick William, Iyengar, Prasanna Vasudevan, Muñoz-Couselo, Eva, Nuciforo, Paolo, Cortés, Javier, Nötzel, Christopher, Kumarakula

Journal:

Journal of Experimental Medicine

Year:

2018

Language:

english

File:

PDF, 3.51 MB

english, 2018

92

Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer

Powles, Ryan L., Redmond, David, Sotiriou, Christos, Loi, Sherene, Fumagalli, Debora, Nuciforo, Paolo, Harbeck, Nadia, de Azambuja, Evandro, Sarp, Severine, Di Cosimo, Serena, Huober, Jens, Baselga, J

Journal:

Year:

2018

Language:

english

File:

PDF, 633 KB

english, 2018

93

PAM50 intrinsic subtype in hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) treated with exemestane (EXE) in combination with everolimus (EVE) or placebo (PBO): A correlative analysis of the phase III BOLERO-2 trial

Prat, A., Brase, J.C., Cheng, Y., Nuciforo, P., Paré, L., Pascual, T., Martinez, D., Galvan, P., Vidal, M., Adamo, B., Hortobagyi, G., Baselga, J., Ciruelos, E.

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 64 KB

english, 2018

94

An Atlas of Altered Expression of Deubiquitinating Enzymes in Human Cancer

Luise, Chiara, Capra, Maria, Donzelli, Maddalena, Mazzarol, Giovanni, Jodice, Maria Giovanna, Nuciforo, Paolo, Viale, Giuseppe, Di Fiore, Pier Paolo, Confalonieri, Stefano, Masucci, Maria

Journal:

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

95

Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma

Vaillant, Catherine, Valdivieso, Paola, Nuciforo, Sandro, Kool, Marcel, Schwarzentruber-Schauerte, Alexandra, Méreau, Hélène, Cabuy, Erik, Lobrinus, Johannes A., Pfister, Stefan, Zuniga, Aimée, Frank,

Journal:

Year:

2015

Language:

english

File:

PDF, 7.51 MB

english, 2015

96

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

Nuciforo, Sandro, Fofana, Isabel, Matter, Matthias S., Blumer, Tanja, Calabrese, Diego, Boldanova, Tujana, Piscuoglio, Salvatore, Wieland, Stefan, Ringnalda, Femke, Schwank, Gerald, Terracciano, Luigi

Journal:

Year:

2018

Language:

english

File:

PDF, 6.57 MB

english, 2018

97

1635PFGFR 360° resistance: Establishing a translational research framework in FGFR-altered (FGFRalt) patients (pt) treated with fibroblast growth factor receptor inhibitors (FGFRinh)

Hierro, C., Sánchez-Guixé, M., Ruiz-Pace, F., Jimenez, J., Maynes, L., Azaro, A., Martin-Liberal, J., Ochoa de Olza, M., Braña, I., Vieito, M., Villanueva, A., Palmer, H.G., Arribas, J., Nuciforo, P.,

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 82 KB

english, 2017

98

66PAdapting a prescreening program to match molecular alterations in over 5,000 patients’ tumors with targeted agents and immunotherapies in early clinical trials over the last 8 years

Aguilar, S, Vivancos, A, Nuciforo, P, Viaplana, C, Ruiz-Pace, F, Sanchez, E, Rodon, J, Tabernero, J, Garralda, E, Dienstmann, R

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

99

284OPrimary results of the first nationwide molecular screening program in Spain for patients with advanced breast cancer (AGATA SOLTI-1301 study)

Pernas, S, Villagrasa, P, Vivancos, A, Scaltriti, M, Rodon, J, Burgues, O, Nuciforo, P G, Canes, J, Dueñas, M, Vidal, M, Lluch, A, Perelló, A, Llombart, A, Dorca, J, Montaño, Á, Oliveira, M, Ribas, G,

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 93 KB

english, 2018

100

432PDPrognostic impact of RNA expression profile (EP) in the phase III DECISION trial for patients with advanced radioactive-iodine refractory differentiated thyroid cancer (DTC)

Matos, I., Mancuso, F., Iglesias, C., Nuciforo, P., Zafón, C., Palmer, H.G., Ogbah, Z., Muños, L., Villacampa Javierre, G., Peña, C., Brose, M.S., Schlumberger, M., Vivancos, A., Capdevila, J.

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 101 KB

english, 2017