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51

Paradoxical Effect of Isoniazid on the Activity of Rifampin-Pyrazinamide Combination in a Mouse Model of Tuberculosis

Almeida, D., Nuermberger, E., Tasneen, R., Rosenthal, I., Tyagi, S., Williams, K., Peloquin, C., Grosset, J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 688 KB

english, 2009

52

Promising Clinical Efficacy of Streptomycin-Rifampin Combination for Treatment of Buruli Ulcer (Mycobacterium ulcerans Disease)

Chauty, A., Ardant, M.-F., Adeye, A., Euverte, H., Guedenon, A., Johnson, C., Aubry, J., Nuermberger, E., Grosset, J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

53

Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis

Tyagi, S., Nuermberger, E., Yoshimatsu, T., Williams, K., Rosenthal, I., Lounis, N., Bishai, W., Grosset, J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

54

Evaluation of New Antituberculosis Drugs in Mouse Models

Davies, G. R., Pym, A. S., Mitchison, D. A., Nuermberger, E. L., Grosset, J. H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 37 KB

english, 2007

55

Enhanced Bactericidal Activity of Rifampin and/or Pyrazinamide When Combined with PA-824 in a Murine Model of Tuberculosis

Tasneen, R., Tyagi, S., Williams, K., Grosset, J., Nuermberger, E.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

56

In Vivo Validation of the Mutant Selection Window Hypothesis with Moxifloxacin in a Murine Model of Tuberculosis

Almeida, D., Nuermberger, E., Tyagi, S., Bishai, W. R., Grosset, J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 85 KB

english, 2007

57

Activity of ketoconazole against Mycobacterium tuberculosis in vitro and in the mouse model

Byrne, S. T., Denkin, S. M., Gu, P., Nuermberger, E., Zhang, Y.

Journal:

Journal of Medical Microbiology

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

58

Sterilizing Activities of Novel Combinations Lacking First- and Second-Line Drugs in a Murine Model of Tuberculosis

Williams, K., Minkowski, A., Amoabeng, O., Peloquin, C. A., Taylor, D., Andries, K., Wallis, R. S., Mdluli, K. E., Nuermberger, E. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 151 KB

english, 2012

59

Potent Rifamycin-Sparing Regimen Cures Guinea Pig Tuberculosis as Rapidly as the Standard Regimen

Dutta, N. K., Alsultan, A., Gniadek, T. J., Belchis, D. A., Pinn, M. L., Mdluli, K. E., Nuermberger, E. L., Peloquin, C. A., Karakousis, P. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 370 KB

english, 2013

60

Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife?

Converse, Paul J, Nuermberger, Eric L, Almeida, Deepak V, Grosset, Jacques H

Journal:

Future Microbiology

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

61

Comparison of the 'Denver regimen' against acute tuberculosis in the mouse and guinea pig

Ahmad, Z., Nuermberger, E. L., Tasneen, R., Pinn, M. L., Williams, K. N., Peloquin, C. A., Grosset, J. H., Karakousis, P. C.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2010

Language:

english

File:

PDF, 176 KB

english, 2010

62

Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis

Tasneen, R., Li, S.-Y., Peloquin, C. A., Taylor, D., Williams, K. N., Andries, K., Mdluli, K. E., Nuermberger, E. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2011

Language:

english

File:

PDF, 668 KB

english, 2011

63

Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models

Converse, P. J., Karakousis, P. C., Klinkenberg, L. G., Kesavan, A. K., Ly, L. H., Allen, S. S., Grosset, J. H., Jain, S. K., Lamichhane, G., Manabe, Y. C., McMurray, D. N., Nuermberger, E. L., Bishai

Journal:

Infection and Immunity

Year:

2009

Language:

english

File:

PDF, 2.89 MB

english, 2009

64

Reply to "Contradictory Results with High-Dosage Rifamycin in Mice and Humans"

Nuermberger, E. L., Rosenthal, I. M., Tasneen, R., Peloquin, C. A., Mdluli, K. E., Karakousis, P. C., Grosset, J. H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 82 KB

english, 2013

65

Significance of macrolide resistance in Streptococcus pneumoniae

Nuermberger, E. L.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2003

Language:

english

File:

PDF, 74 KB

english, 2003

66

Pipeline of drugs for related diseases

Dooley, Kelly E., Nuermberger, Eric L., Diacon, Andreas H.

Journal:

Current Opinion in HIV and AIDS

Year:

2013

Language:

english

File:

PDF, 230 KB

english, 2013

67

Combination Chemotherapy with the Nitroimidazopyran PA-824 and First-Line Drugs in a Murine Model of Tuberculosis

Nuermberger, E., Rosenthal, I., Tyagi, S., Williams, K. N., Almeida, D., Peloquin, C. A., Bishai, W. R., Grosset, J. H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

68

Reply to Wargo and Eiland

Francis, J. S., Carroll, K., Nuermberge, E., Bartlett, J. G.

Journal:

Clinical Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 62 KB

english, 2005

69

Repeated Administration of High-Dose Intermittent Rifapentine Reduces Rifapentine and Moxifloxacin Plasma Concentrations

Dooley, K., Flexner, C., Hackman, J., Peloquin, C. A., Nuermberger, E., Chaisson, R. E., Dorman, S. E.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 147 KB

english, 2008

70

Activity of the Fluoroquinolone DC-159a in the Initial and Continuation Phases of Treatment of Murine Tuberculosis

Ahmad, Z., Minkowski, A., Peloquin, C. A., Williams, K. N., Mdluli, K. E., Grosset, J. H., Nuermberger, E. L.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

71

Moxifloxacin-containing Regimen Greatly Reduces Time to Culture Conversion in Murine Tuberculosis

Nuermberger, Eric L., Yoshimatsu, Tetsuyuki, Tyagi, Sandeep, O'Brien, Richard J., Vernon, Andrew N., Chaisson, Richard E., Bishai, William R., Grosset, Jacques H.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

72

Noninvasive Pulmonary [18F]-2-Fluoro-Deoxy-D-Glucose Positron Emission Tomography Correlates with Bactericidal Activity of Tuberculosis Drug Treatment

Davis, S. L., Nuermberger, E. L., Um, P. K., Vidal, C., Jedynak, B., Pomper, M. G., Bishai, W. R., Jain, S. K.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 831 KB

english, 2009

73

Biphasic Kill Curve of Isoniazid Reveals the Presence of Drug‐Tolerant, Not Drug‐Resistant, Mycobacterium tuberculosis in the Guinea Pig

Ahmad, Zahoor, Klinkenberg, Lee G., Pinn, Michael L., Fraig, Mostafa M., Peloquin, Charles A., Bishai, William R., Nuermberger, Eric L., Grosset, Jacques H., Karakousis, Petros C.

Journal:

The Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 8.83 MB

english, 2009

74

Accelerated Detection of Mycobacterium tuberculosis Genes Essential for Bacterial Survival in Guinea Pigs, Compared with Mice

Jain, Sanjay K., Hernandez‐Abanto, S. Moises, Cheng, Qi‐Jian, Singh, Prabhpreet, Ly, Lan H., Klinkenberg, Lee G., Morrison, Norman E., Converse, Paul J., Nuermberger, Eric, Grosset, Jacques, McMurray,

Journal:

The Journal of Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 1022 KB

english, 2007

75

Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Dutta, N. K., Illei, P. B., Peloquin, C. A., Pinn, M. L., Mdluli, K. E., Nuermberger, E. L., Grosset, J. H., Karakousis, P. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 272 KB

english, 2012

76

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

Ahmad, Z., Pinn, M. L., Nuermberger, E. L., Peloquin, C. A., Grosset, J. H., Karakousis, P. C.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2010

Language:

english

File:

PDF, 271 KB

english, 2010

77

The Clinical Significance of Macrolide‐Resistant Streptococcus pneumoniae: It’s All Relative

Nuermberger, Eric, Bishai, William R.

Journal:

Clinical Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 85 KB

english, 2004

78

Correction for Lanoix et al., Novel Regimens Identified in Mice for Treatment of Latent Tuberculosis Infection in Contacts of Patients with Multidrug-Resistant Tuberculosis

Lanoix, Jean-Philippe, Betoudji, Fabrice, Nuermberger, Eric

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 99 KB

english, 2015

79

Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis

Yoshimatsu, T., Nuermberger, E., Tyagi, S., Chaisson, R., Bishai, W., Grosset, J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2002

Language:

english

File:

PDF, 430 KB

english, 2002

80

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

Irwin, S. M., Driver, E., Lyon, E., Schrupp, C., Ryan, G., Gonzalez-Juarrero, M., Basaraba, R. J., Nuermberger, E. L., Lenaerts, A. J.

Journal:

Disease Models & Mechanisms

Year:

2015

Language:

english

File:

PDF, 1.83 MB

english, 2015

81

Antibiotic Resistance in Streptococcus pneumoniae: What Does the Future Hold?

Nuermberger, E. L., Bishai, W. R.

Journal:

Clinical Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 110 KB

english, 2004

82

Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice

Almeida, Deepak, Converse, Paul J., Ahmad, Zahoor, Dooley, Kelly E., Nuermberger, Eric L., Grosset, Jacques H., Diemert, David Joseph

Journal:

PLoS Neglected Tropical Diseases

Year:

2011

Language:

english

File:

PDF, 541 KB

english, 2011

83

Mouse Model of Necrotic Tuberculosis Granulomas Develops Hypoxic Lesions

Harper, J., Skerry, C., Davis, S. L., Tasneen, R., Weir, M., Kramnik, I., Bishai, W. R., Pomper, M. G., Nuermberger, E. L., Jain, S. K.

Journal:

The Journal of Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

84

Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease

Converse, Paul J., Xing, Yalan, Kim, Ki Hyun, Tyagi, Sandeep, Li, Si-Yang, Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H., Kishi, Yoshito, Phillips, Richard O.

Journal:

PLoS Neglected Tropical Diseases

Year:

2014

Language:

english

File:

PDF, 927 KB

english, 2014

85

Bactericidal Activity Does Not Predict Sterilizing Activity: The Case of Rifapentine in the Murine Model of Mycobacterium ulcerans Disease

Almeida, Deepak V., Converse, Paul J., Li, Si-Yang, Tyagi, Sandeep, Nuermberger, Eric L., Grosset, Jacques H., Johnson, Christian

Journal:

PLoS Neglected Tropical Diseases

Year:

2013

Language:

english

File:

PDF, 395 KB

english, 2013

86

Rapid, Serial, Non-invasive Assessment of Drug Efficacy in Mice with AutoluminescentMycobacterium ulcerans Infection

Zhang, Tianyu, Li, Si-Yang, Converse, Paul J., Grosset, Jacques H., Nuermberger, Eric L., Ricaldi, Jessica N.

Journal:

PLoS Neglected Tropical Diseases

Year:

2013

Language:

english

File:

PDF, 578 KB

english, 2013

87

Nonclinical Models for Antituberculosis Drug Development: A Landscape Analysis

Gumbo, Tawanda, Lenaerts, Anne J., Hanna, Debra, Romero, Klaus, Nuermberger, Eric

Journal:

The Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

88

BCG-Mediated Protection against Mycobacterium ulcerans Infection in the Mouse

Converse, Paul J., Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H., Roy, Craig R.

Journal:

PLoS Neglected Tropical Diseases

Year:

2011

Language:

english

File:

PDF, 924 KB

english, 2011

89

Assessing the Landscape of Tools and Approaches for Novel Tuberculosis Regimen Development

Nuermberger, Eric, Hanna, Debra

Journal:

The Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

90

Systematic Analysis of Hollow Fiber Model of Tuberculosis Experiments

Pasipanodya, Jotam G., Nuermberger, Eric, Romero, Klaus, Hanna, Debra, Gumbo, Tawanda

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 186 KB

english, 2015

91

Correlations Between the Hollow Fiber Model of Tuberculosis and Therapeutic Events in Tuberculosis Patients: Learn and Confirm

Gumbo, Tawanda, Pasipanodya, Jotam G., Nuermberger, Eric, Romero, Klaus, Hanna, Debra

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 139 KB

english, 2015

92

Forecasting Accuracy of the Hollow Fiber Model of Tuberculosis for Clinical Therapeutic Outcomes

Gumbo, Tawanda, Pasipanodya, Jotam G., Romero, Klaus, Hanna, Debra, Nuermberger, Eric

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 167 KB

english, 2015

93

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] A105. NONTUBERCULOUS MYCOBACTERIA: PATHOPHYSIOLOGY TO TREATMENT - Mouse Models Of Pulmonary Disease After Aerosol Infection With Non-Tuberculous Mycobacteria

ANDREJAK, CLAIRE, Tyagi, Sandeep, Almeida, Deepak, Nuermberger, Eric L., Grosset, Jacques H.E.

Year:

2011

Language:

english

File:

PDF, 17 KB

english, 2011

94

Primary HIV infection presenting as limbic encephalitis and rhabdomyolysis

Ferrada, M. A., Xie, Y., Nuermberger, E.

Journal:

International Journal of STD & AIDS

Year:

2014

Language:

english

File:

PDF, 201 KB

english, 2014

95

Short-Course Therapy with Daily Rifapentine in a Murine Model of Latent Tuberculosis Infection

Zhang, Tianyu, Zhang, Ming, Rosenthal, Ian M., Grosset, Jacques H., Nuermberger, Eric L.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 190 KB

english, 2009

96

High-dose fluoroquinolones in short-course regimens for treatment of MDR-TB: the way forward? [Editorial]

Yew, Wing-Wai, Nuermberger, Eric

Journal:

The International Journal of Tuberculosis and Lung Disease

Year:

2013

File:

PDF, 123 KB

2013

97

Potent Twice-Weekly Rifapentine-containing Regimens in Murine Tuberculosis

Rosenthal, Ian M., Williams, Kathy, Tyagi, Sandeep, Peloquin, Charles A., Vernon, Andrew A., Bishai, William R., Grosset, Jacques H., Nuermberger, Eric L.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

98

Isoniazid or Moxifloxacin in Rifapentine-based Regimens for Experimental Tuberculosis?

Rosenthal, Ian M., Zhang, Ming, Almeida, Deepak, Grosset, Jacques H., Nuermberger, Eric L.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

99

High-dose fluoroquinolones in short-course regimens for treatment of MDR-TB: the way forward? [Editorial]

Yew, Wing-Wai, Nuermberger, Eric

Journal:

The International Journal of Tuberculosis and Lung Disease

Year:

2013

Language:

english

File:

PDF, 123 KB

english, 2013

100

Rifapentine, Moxifloxacin, or DNA Vaccine Improves Treatment of Latent Tuberculosis in a Mouse Model

Nuermberger, Eric, Tyagi, Sandeep, Williams, Kathy N., Rosenthal, Ian, Bishai, William R., Grosset, Jacques H.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 94 KB

english, 2005