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1

Isolation and primary structure of urotensin II from the brain of a tetrapod, the frog Rana ridibunda

J.Michael Conlon, Finbarr O'Harte, D.David Smith, Marie-Christine Tonon, Hubert Vaudry

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 389 KB

english, 1992

2

N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic β-cell-associated gene expression

Hui-Kang Liu, Brian D. Green, Victor A. Gault, Jane T. McCluskey, Neville H. McClenaghan, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

Cell Biology International

Year:

2004

Language:

english

File:

PDF, 93 KB

english, 2004

3

Characterisation and biological activity of Glu3 amino acid substituted GIP receptor antagonists

Victor A. Gault, Kerry Hunter, Nigel Irwin, Brian D. Green, Brett Greer, Patrick Harriott, Finbarr P.M. O’Harte, Peter R. Flatt

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 289 KB

english, 2007

4

Blue whiting ( Micromesistius poutassou ) muscle protein hydrolysate with in vitro and in vivo antidiabetic properties

Harnedy, Pádraigín A., Parthsarathy, Vadivel, McLaughlin, Chris M., O'Keeffe, Martina B., Allsopp, Philip J., McSorley, Emeir M., O'Harte, Finbarr P.M., FitzGerald, Richard J.

Journal:

Journal of Functional Foods

Year:

2018

Language:

english

File:

PDF, 841 KB

english, 2018

5

Comparison of the anti-diabetic effects of GIP- and GLP-1-receptor activation in obese diabetic (ob/ob) mice: studies with DPP IV resistant N-AcGIP and exendin(1–39)amide

Nigel Irwin, Paula L. McClean, Roslyn S. Cassidy, Finbarr P. M. O'Harte, Brian D. Green, Victor A. Gault, Patrick Harriott, Peter R. Flatt

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2007

Language:

english

File:

PDF, 153 KB

english, 2007

6

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide

Kalyana C. Venneti, J. Paul G. Malthouse, Finbarr P.M. O'Harte, Chandralal M. Hewage

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

7

The bioactive conformation of glucose-dependent insulinotropic polypeptide by NMR and CD spectroscopy

Iñigo Alaña, J. Paul G. Malthouse, Finbarr P. M. O'Harte, Chandralal M. Hewage

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 419 KB

english, 2007

8

The importance of developing world haematology

Nichola Cooper, Daniel Hart, Imelda Bates, Finbarr E. Cotter

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 33 KB

english, 2011

9

Ranakinin: A Novel NK1 Tachykinin Receptor Agonist Isolated with Neurokinin B from the Brain of the Frog Rana ridibunda

Finbarr O'Harte, Elizabeth Burcher, Sandor Lovas, D. David Smith, Hubert Vaudry, J. Michael Conlon

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 571 KB

english, 1991

10

Carassin: A Tachykinin That Is Structurally Related to Neuropeptide-γ from the Brain of the Goldfish

J. Michael Conlon, Finbarr O'Harte, Richard E. Peter, Olivier Kah

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 447 KB

english, 1991

11

Detection of glycated gastric inhibitory polypeptide within the intestines of diabetic obese (ob/ob) mice

Mark H. Mooney, Yasser H. A. Abdel-Wahab, Linda M. Morgan, Finbarr P. M. O’Harte, Peter R. Flatt

Journal:

Endocrine (Springer)

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

12

Targeting β-cell cyclic 3′5′adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review

Brian Furman, Nigel Pyne, Peter Flatt, Finbarr O'Harte

Journal:

Journal of Pharmacy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

13

Sequential changes in propionate metabolism during the development of cobalt/vitamin B12deficiency in sheep

D. Glenn Kennedy, Finbarr P. M. O'Harte, W. John Blanchflower, Desmond A. Rice

Journal:

Biological Trace Element Research

Year:

1991

Language:

english

File:

PDF, 554 KB

english, 1991

14

Structural characterization of tachykinins (neuropeptide γ, neurokinin A, and substance P) from a reptile, Alligator mississipiensis

Yunxia Wang, Finbarr O'Harte, J.Michael Conlon

Journal:

General and Comparative Endocrinology

Year:

1992

Language:

english

File:

PDF, 765 KB

english, 1992

15

Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide

Nigel Irwin, Gillian C. Clarke, Brian D. Green, Brett Greer, Patrick Harriott, Victor A. Gault, Finbarr P.M. O’Harte, Peter R. Flatt

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 765 KB

english, 2006

16

Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties

Barry D. Kerr, Nigel Irwin, Finbarr P.M. O’Harte, Clifford J. Bailey, Peter R. Flatt, Victor A. Gault

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 797 KB

english, 2009

17

Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1

Brian D. Green, Nigel Irwin, Nicola A. Duffy, Victor A. Gault, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 494 KB

english, 2006

18

Effects of antidiabetic drugs on dipeptidyl peptidase IV activity: Nateglinide is an inhibitor of DPP IV and augments the antidiabetic activity of glucagon-like peptide-1

Nicola A. Duffy, Brian D. Green, Nigel Irwin, Victor A. Gault, Aine M. McKillop, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.29 MB

english, 2007

19

Stable agonist of glucose-dependent insulinotropic polypeptide (GIP) restores pancreatic beta cell glucose responsiveness but not glucose intolerance in aging mice

Nigel Irwin, Brian D. Green, Victor A. Gault, Patrick Harriot, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

Experimental Gerontology

Year:

2006

Language:

english

File:

PDF, 112 KB

english, 2006

20

Addition of metformin to exogenous glucagon-like peptide–1 results in increased serum glucagon-like peptide–1 concentrations and greater glucose lowering in type 2 diabetes mellitus

Joy Cuthbertson, Steven Patterson, Finbarr P. O'Harte, Patrick M. Bell

Journal:

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

21

Glucose-dependent insulinotropic polypeptide (GIP): anti-diabetic and anti-obesity potential?

Victor A. Gault, Finbarr P.M. O’Harte, Peter R. Flatt

Journal:

Year:

2003

Language:

english

File:

PDF, 301 KB

english, 2003

22

Characterization of the Cellular and Metabolic Effects of a Novel Enzyme-Resistant Antagonist of Glucose-Dependent Insulinotropic Polypeptide

Victor A. Gault, Finbarr P.M. O'Harte, Patrick Harriott, Peter R. Flatt

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 276 KB

english, 2002

23

Primary structures of the bombesin-like neuropeptides in frog brain show that bombesin is not the amphibian gastrin-releasing peptide

J.Michael Conlon, Finbarr O'Harte, Hubert Vaudry

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 352 KB

english, 1991

24

The primary structure of a PYY-related peptide from chicken intestine suggests an anomalous site of cleavage of the signal peptide in preproPYY

J.Michael Conlon, Finbarr O'Harte

Journal:

Year:

1992

Language:

english

File:

PDF, 285 KB

english, 1992

25

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1–30)amide

Iñigo Alaña, Chandralal M. Hewage, J. Paul G. Malthouse, Jeremy C. Parker, Victor A. Gault, Finbarr P.M. O'Harte

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 412 KB

english, 2004

26

Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects

Aine M. McKillop, Nicola A. Duffy, John R. Lindsay, Finbarr P.M. O’Harte, Patrick M. Bell, Peter R. Flatt

Journal:

Diabetes Research and Clinical Practice

Year:

2008

Language:

english

File:

PDF, 610 KB

english, 2008

27

Effects on glucose homeostasis and insulin secretion of long term activation of the glucose-dependent insulinotropic polypeptide (GIP) receptor by N-AcGIP(LysPAL37) in normal mice

Nigel Irwin, Brian D. Green, Victor A. Gault, Roslyn S. Cassidy, Finbarr P.M. O’Harte, Patrick Harriott, Peter R. Flatt

Journal:

Year:

2006

Language:

english

File:

PDF, 456 KB

english, 2006

28

Biological activity and antidiabetic potential of synthetic fragment peptides of glucose-dependent insulinotropic polypeptide, GIP(1-16) and (Pro3)GIP(1-16)

Nigel Irwin, Brian D. Green, Jeremy C. Parker, Victor A. Gault, Finbarr P.M. O'Harte, Peter R. Flatt

Journal:

Regulatory Peptides

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

29

Glucose-dependent insulinotropic polypeptide analogues and their therapeutic potential for the treatment of obesity-diabetes

Victor A. Gault, Peter R. Flatt, Finbarr P.M. O’Harte

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

30

Degradation, cyclic adenosine monophosphate production, insulin secretion, and glycemic effects of two novel N-terminal Ala2-substituted analogs of glucose-dependent insulinotropic polypeptide with preserved biological activity in vivo

Victor A Gault, Finbarr P.M O’Harte, Patrick Harriott, Peter R Flatt

Journal:

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

31

Evaluation of the site(s) of glycation in human proinsulin by ion-trap LCQ electrospray ionization mass spectrometry

Aine M. McKillop, Angela Meade, Peter R. Flatt, Finbarr P.M. O'Harte

Journal:

Regulatory Peptides

Year:

2003

Language:

english

File:

PDF, 412 KB

english, 2003

32

N-terminal glycation of cholecystokinin-8 abolishes its insulinotropic action on clonal pancreatic B-cells

Yasser H.A. Abdel-Wahab, Finbarr P.M. O’Harte, Mark H. Mooney, J.Michael Conlon, Peter R. Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1999

Language:

english

File:

PDF, 298 KB

english, 1999

33

Identification of the site of glycation of human insulin

Finbarr P.M. O'Harte, Peter Højrup, Christopher R. Barnett, Peter R. Flatt

Journal:

Year:

1996

Language:

english

File:

PDF, 955 KB

english, 1996

34

Effects of Non-Glycated and Glycated Glucagon-Like Peptide-1(7-36) Amide on Glucose Metabolism in Isolated Mouse Abdominal Muscle

Finbarr P.M O’Harte, Alison M Gray, Yasser H.A Abdel-Wahab, Peter R Flatt

Journal:

Year:

1997

Language:

english

File:

PDF, 350 KB

english, 1997

35

Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle

Alison C Boyd, Yasser H.A Abdel-Wahab, Aine M McKillop, Helene McNulty, Christopher R Barnett, Finbarr P.M O’Harte, Peter R Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2000

Language:

english

File:

PDF, 251 KB

english, 2000

36

Evaluation of glycated glucagon-like peptide-1(7-36)amide in intestinal tissue of normal and diabetic animal models

Mark H Mooney, Yasser H.A Abdel-Wahab, Aine M McKillop, Finbarr P.M O’Harte, Peter R Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

37

Amino terminal glycation of gastric inhibitory polypeptide enhances its insulinotropic action on clonal pancreatic B-cells

Finbarr P.M. O’Harte, Yasser H.A. Abdel-Wahab, J.Michael Conlon, Peter R. Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1998

Language:

english

File:

PDF, 411 KB

english, 1998

38

N-terminally modified glucagon-like peptide-1(7–36) amide exhibits resistance to enzymatic degradation while maintaining its antihyperglycaemic activity in vivo

Finbarr P.M O’Harte, Mark H Mooney, Alan Lawlor, Peter R Flatt

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2000

Language:

english

File:

PDF, 463 KB

english, 2000

39

Vitamin C supplementation decreases insulin glycation and improves glucose homeostasis in obese hyperglycemic (ob/ob) mice

Yasser H.A. Abdel-Wahab, Finbarr P.M. O'Harte, Mark H. Mooney, Christopher R. Barnett, Peter R. Flatt

Journal:

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

40

Meal-induced 24-hour profile of circulating glycated insulin in type 2 diabetic subjects measured by a novel radioimmunoassay

John R. Lindsay, Aine M. McKillop, Mark H. Mooney, Peter R. Flatt, Patrick M. Bell, Finbarr P.M. O[apos ]Harte

Journal:

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

41

Rabbit neuromedin U-25: lack of conservation of a posttranslational processing site

Reinhard Kage, Finbarr O'Harte, Lars Thim, J.Michael Conlon

Journal:

Regulatory Peptides

Year:

1991

Language:

english

File:

PDF, 363 KB

english, 1991

42

Measurement of T-kinin in rat plasma using a specific radioimmunoassay

Finbarr O'Harte, D. David Smith, Stephen J. Lanspa, J. Michael Conlon

Journal:

Regulatory Peptides

Year:

1992

Language:

english

File:

PDF, 562 KB

english, 1992

43

Isolation, structural characterization and pharmacological activity of dog neuromedin U

Finbarr O'Harte, Charles S. Bockman, Peter W. Abel, J.Michael Conlon

Journal:

Year:

1991

Language:

english

File:

PDF, 435 KB

english, 1991

44

Primary structure and pharmacological activity of a nonapeptide related to neuromedin U isolated from chicken intestine

Finbarr O'Harte, Charles S. Bockman, Wanyun Zeng, Peter W. Abel, Steven Harvey, J.Michael Conlon

Journal:

Year:

1991

Language:

english

File:

PDF, 412 KB

english, 1991

45

Localization of neurokinin B in the central nervous system of the rat

István Merchenthaler, Jerome L. Maderdrut, Finbarr O'Harte, J.Michael Conlon

Journal:

Year:

1992

Language:

english

File:

PDF, 2.23 MB

english, 1992

46

GIP(Lys 16 PAL) and GIP(Lys 37 PAL): Novel Long-Acting Acylated Analogues of Glucose-Dependent Insulinotropic Polypeptide with Improved Antidiabetic Potential

Irwin, Nigel, O'Harte, Finbarr P. M., Gault, Victor A., Green, Brian D., Greer, Brett, Harriott, Patrick, Bailey, Clifford J., Flatt, Peter R.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 233 KB

english, 2006

47

A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL16), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones

Marenah, Lamin, McCluskey, Jane T., Abdel-Wahab, Yasser H.A., O'Harte, Finbarr P.M., McClenaghan, Neville H., Flatt, Peter R.

Journal:

Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

48

Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein

Cullen, Kirsty S., Al-Oanzi, Ziad H., O'Harte, Finbarr P.M., Agius, Loranne, Arden, Catherine

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

49

(pGlu-Gln)-CCK-8[mPEG]: A novel, long-acting, mini-PEGylated cholecystokinin (CCK) agonist that improves metabolic status in dietary-induced diabetes

Irwin, Nigel, Frizelle, Pamela, O'Harte, Finbarr P.M., Flatt, Peter R.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2013

Language:

english

File:

PDF, 470 KB

english, 2013

50

desHis1Glu9-glucagon-[mPEG] and desHis1Glu9(Lys30PAL)-glucagon: Long-acting peptide-based PEGylated and acylated glucagon receptor antagonists with potential antidiabetic activity

Irwin, Nigel, Franklin, Zara J., O'Harte, Finbarr P.M.

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

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