OʼRahilly, Stephen: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

51

Evidence for Linkage of Stature to Chromosome 3p26 in a Large U.K. Family Data Set Ascertained for Type 2 Diabetes

Steven Wiltshire, Timothy M. Frayling, Andrew T. Hattersley, Graham A. Hitman, Mark Walker, Jonathan C. Levy, Stephen O'Rahilly, Christopher J. Groves, Stephan Menzel, Lon R. Cardon, Mark I. McCarthy

Journal:

The American Journal of Human Genetics

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

52

Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action

Barroso, Inês, Luan, Jian'an, Middelberg, Rita P. S., Harding, Anne-Helen, Franks, Paul W., Jakes, Rupert W., Clayton, David, Schafer, Alan J., O'Rahilly, Stephen, Wareham, Nicholas J.

Journal:

Year:

2003

Language:

english

File:

PDF, 296 KB

english, 2003

53

Tumor Necrosis Factor-Induced Cytotoxicity is Not Related to Rates of Mitochondrial Morphological Abnormalities or Autophagy-Changes that can be Mediated by TNFR-I or TNFR-II

Johannes B. Prins, Elizabeth C. Ledgerwood, Paul Ameloot, Peter Vandenabeele, Paulo R. Faraco, Nicholas A. Bright, Stephen O'Rahilly, John R. Bradley

Journal:

Bioscience Reports

Year:

1998

Language:

english

File:

PDF, 2.81 MB

english, 1998

54

01-P010 Prader–Willi Syndrome and small nucleolar RNAs

Carolin Purmann, Giles Yeo, Sadaf Farooqi, Stephen O’Rahilly

Journal:

Mechanisms of Development

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

55

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

Wheeler, Eleanor, Huang, Ni, Bochukova, Elena G, Keogh, Julia M, Lindsay, Sarah, Garg, Sumedha, Henning, Elana, Blackburn, Hannah, Loos, Ruth J F, Wareham, Nick J, O'Rahilly, Stephen, Hurles, Matthew

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

56

Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

Farooqi, I. Sadaf, Jebb, Susan A., Langmack, Gill, Lawrence, Elizabeth, Cheetham, Christopher H., Prentice, Andrew M., Hughes, Ieuan A., McCamish, Mark A., O'Rahilly, Stephen

Journal:

Boston Medical and Surgical Journal

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

57

Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

Farooqi, I. Sadaf, Keogh, Julia M., Yeo, Giles S.H., Lank, Emma J., Cheetham, Tim, O'Rahilly, Stephen

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 629 KB

english, 2003

58

The Metabolic Syndrome: Peroxisome Proliferator-Activated Receptor γ and Its Therapeutic Modulation

Gurnell, Mark, Savage, David B., Chatterjee, V. Krishna K., O’Rahilly, Stephen

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

59

Insulin Resistance (Insulin Action and Its Disturbances in Disease) || Front Matter

Kumar, Sudhesh, O'Rahilly, Stephen

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

60

Mutations in ligands and receptors of the leptin–melanocortin pathway that lead to obesity

Farooqi, I Sadaf, O'Rahilly, Stephen

Journal:

Nature Clinical Practice Endocrinology and Metabolism

Year:

2008

Language:

english

File:

PDF, 304 KB

english, 2008

61

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

Sim, M. F. Michelle, Talukder, M. Mesbah Uddin, Dennis, Rowena J., O’Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.

Journal:

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

62

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1

Sim, M.F. Michelle, Dennis, Rowena J., Aubry, Evelyne M., Ramanathan, Nardev, Sembongi, Hiroshi, Saudek, Vladimir, Ito, Daisuke, O'Rahilly, Stephen, Siniossoglou, Symeon, Rochford, Justin J.

Journal:

Molecular Metabolism

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

63

The coding sequence of POMC and obesity and appetite in Labrador retriever dogs

Raffan, Eleanor, Becker, Julia, Yeo, Giles, O'Rahilly, Stephen

Journal:

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

64

BETA BLOCKERS, BLOOD SUGARS, AND THIAZIDES

Gove, I., Kendall, M.J., O'Rahilly, Stephen

Journal:

Year:

1985

Language:

english

File:

PDF, 304 KB

english, 1985

65

Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency

Frank, Graeme R., Fox, Joyce, Candela, Ninfa, Jovanovic, Zorica, Bochukova, Elena, Levine, Jeremiah, Papenhausen, Peter R., O'Rahilly, Stephen, Farooqi, I. Sadaf

Journal:

Molecular Genetics and Metabolism

Year:

2013

Language:

english

File:

PDF, 503 KB

english, 2013

66

Shedding pounds after going under the knife: Guts over glory—why diets fail

Larder, Rachel, O'Rahilly, Stephen

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

67

Lamin Expression in Human Adipose Cells in Relation to Anatomical Site and Differentiation State

Lelliott, Christopher J., Logie, Lisa, Sewter, Ciaran P., Berger, Dirk, Jani, Piyush, Blows, Fiona, O’Rahilly, Stephen, Vidal-Puig, Antonio

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2002

Language:

english

File:

PDF, 262 KB

english, 2002

68

Genetic Syndromes of Severe Insulin Resistance

Semple, Robert K., Savage, David B., Cochran, Elaine K., Gorden, Phillip, O'Rahilly, Stephen

Journal:

Endocrine Reviews

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

69

Examining the Candidacy of Ghrelin as a Gene Responsible for Variation in Adult Stature in a United Kingdom Population with Type 2 Diabetes

Gueorguiev, Maria, Wiltshire, Steven, Garcia, Edwin A., Mein, Charles, Lecoeur, Cecile, Kristen, Brigitte, Allotey, Rebecca, Hattersley, Andrew T., Walker, Mark, O’Rahilly, Stephen, Froguel, Philippe,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

70

Clinical and Molecular Characterization of a Novel PLIN1 Frameshift Mutation Identified in Patients With Familial Partial Lipodystrophy

Kozusko, Kristina, Tsang, Venessa H.M., Bottomley, William, Cho, Yoon-Hi, Gandotra, Sheetal, Mimmack, Michael, Lim, Koini, Isaac, Iona, Patel, Satish, Saudek, Vladimir, O’Rahilly, Stephen, Srinivasan,

Journal:

Year:

2015

Language:

english

File:

PDF, 2.79 MB

english, 2015

71

Congenital Leptin Deficiency Due to Homozygosity for the Δ133G Mutation: Report of Another Case and Evaluation of Response to Four Years of Leptin Therapy

Gibson, William T., Farooqi, I. Sadaf, Moreau, Mary, DePaoli, Alex M., Lawrence, Elizabeth, O’Rahilly, Stephen, Trussell, Rebecca A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

72

Mutational analysis of the serotonin receptor 5HT2c in severe early-onset human obesity

Gibson, William T, Ebersole, Barbara J, Bhattacharyya, Sumit, Clayton, Peter, Farooqi, I Sadaf, Sealfon, Stuart C, O'Rahilly, Stephen

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2004

File:

PDF, 127 KB

2004

73

Knockdown of diacylglycerol kinase delta inhibits adipocyte differentiation and alters lipid synthesis

Lowe, Christopher E., Zhang, Qifeng, Dennis, Rowena J., Aubry, Evelyne M., O'Rahilly, Stephen, Wakelam, Michael J.O., Rochford, Justin J.

Journal:

Year:

2013

Language:

english

File:

PDF, 875 KB

english, 2013

74

Insulin Resistance (Insulin Action and Its Disturbances in Disease) || Central Regulation of Peripheral Glucose Metabolism

Kumar, Sudhesh, O'Rahilly, Stephen

Year:

2004

Language:

english

File:

PDF, 286 KB

english, 2004

75

Obesity-Associated Melanocortin-4 Receptor Mutations Are Associated With Changes in the Brain Response to Food Cues

van der Klaauw, Agatha A., von dem Hagen, Elisabeth A. H., Keogh, Julia M., Henning, Elana, O'Rahilly, Stephen, Lawrence, Andrew D., Calder, Andrew J., Farooqi, I. Sadaf

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 512 KB

english, 2014

76

Appetite || Genetics of Obesity

Stephen O'Rahilly and I. Sadaf Farooqi

Journal:

Philosophical Transactions Biological Sciences

Year:

2006

Language:

english

File:

PDF, 2.52 MB

english, 2006

77

Effect of Metformin on Glucose Disposal and Hyperinsulinaemia in a 14-Year-Old Boy with Acanthosis Nigricans

Lee, Philip J., Cranston, Iain, Amiel, Stephanie A., O&rsquo, Rahilly, Stephen, Green, Albert Aynsley

Journal:

Hormone Research

Year:

1997

File:

PDF, 866 KB

1997

78

Proteinuric Nephropathy in Acquired and Congenital Generalized Lipodystrophy: Baseline Characteristics and Course during Recombinant Leptin Therapy

Javor, Edward D., Moran, Stephanie Ann, Young, Janice Ryan, Cochran, Elaine K., DePaoli, Alex M., Oral, Elif Arioglu, Turman, Martin A., Blackett, Piers R., Savage, David B., O’Rahilly, Stephen, Balow

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 396 KB

english, 2004

79

Rapid and simultaneous detection of multiple mutations by pooled and multiplex single nucleotide primer extension: application to the study of insulin-responsive glucose transporter and insulin receptor mutations in non-insulindependent diabetes

Krook, Anna, Stratton, Irene M., O'Rahilly, Stephen

Journal:

Human Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 3.98 MB

english, 1992

80

Does Physical Activity Energy Expenditure Explain the Between-Individual Variation in Plasma Leptin Concentrations after Adjusting for Differences in Body Composition?

Franks, Paul W., Farooqi, I. Sadaf, Luan, Jian’an, Wong, Man-Yu, Halsall, Ian, O’Rahilly, Stephen, Wareham, Nicholas J.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2003

Language:

english

File:

PDF, 108 KB

english, 2003

81

Induction of Adipocyte Complement-Related Protein of 30 Kilodaltons by PPARγ Agonists: A Potential Mechanism of Insulin Sensitization

Combs, Terry P., Wagner, John A., Berger, Joel, Doebber, Tom, Wang, Wen-Jun, Zhang, Bei B., Tanen, Michael, Berg, Anders H, O’Rahilly, Stephen, Savage, David B., Chatterjee, Krishna, Weiss, Stuart, La

Journal:

Year:

2002

Language:

english

File:

PDF, 355 KB

english, 2002

82

Genetics of Obesity in Humans

Farooqi, I. Sadaf, O’Rahilly, Stephen

Journal:

Endocrine Reviews

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

83

Impaired Pulsatile Secretion of Insulin in Relatives of Patients with Non-Insulin-Dependent Diabetes

O'Rahilly, Stephen, Turner, Robert C., Matthews, David R.

Journal:

Boston Medical and Surgical Journal

Year:

1988

Language:

english

File:

PDF, 877 KB

english, 1988

84

Proopiomelanocortin and Energy Balance: Insights from Human and Murine Genetics

Coll, Anthony P., Farooqi, I. Sadaf, Challis, Benjamin G., Yeo, Giles S. H., O’Rahilly, Stephen

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

85

Serotonin 5-HT 2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

Lam, Daniel D., Przydzial, Magdalena J., Ridley, Simon H., Yeo, Giles S. H., Rochford, Justin J., O’Rahilly, Stephen, Heisler, Lora K.

Journal:

Year:

2008

Language:

english

File:

PDF, 312 KB

english, 2008

86

Severe Hypoinsulinaemic Hypoglycaemia in a Premature Infant Associated with Poor Weight Gain and Reduced Adipose Tissue

Coelho, Raquel, Wells, Jonathan, Symth, John, Semple, Robert, O&rsquo, Rahilly, Stephen, Eaton, Simon, Hussain, Khalid

Journal:

Hormone Research

Year:

2007

Language:

english

File:

PDF, 294 KB

english, 2007

87

Genetic Variants and Common Diseases — Better Late Than Never

O'Rahilly, Stephen, Wareham, Nicholas J.

Journal:

Boston Medical and Surgical Journal

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006

88

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

Tung, Yi-Chun Loraine, Ayuso, Eduard, Shan, Xiaoye, Bosch, Fatima, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S. H., Bartolomucci, Alessandro

Journal:

Year:

2010

Language:

english

File:

PDF, 490 KB

english, 2010

89

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels

Richards, J. Brent, Waterworth, Dawn, O'Rahilly, Stephen, Hivert, Marie-France, Loos, Ruth J. F., Perry, John R. B., Tanaka, Toshiko, Timpson, Nicholas John, Semple, Robert K., Soranzo, Nicole, Song,

Journal:

Year:

2009

Language:

english

File:

PDF, 661 KB

english, 2009

90

Functional Characterization and Structural Modeling of Obesity Associated Mutations in the Melanocortin 4 Receptor

Tan, Karen, Pogozheva, Irina D., Yeo, Giles S. H., Hadaschik, Dirk, Keogh, Julia M., Haskell-Leuvano, Carrie, O'Rahilly, Stephen, Mosberg, Henry I., Farooqi, I. Sadaf

Journal:

Year:

2009

Language:

english

File:

PDF, 666 KB

english, 2009

91

Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous System

Liu, Qiang, Zhang, Juan, Zerbinatti, Celina, Zhan, Yan, Kolber, Benedict J., Herz, Joachim, Muglia, Louis J., Bu, Guojun, O'Rahilly, Stephen

Journal:

Year:

2011

Language:

english

File:

PDF, 1.76 MB

english, 2011

92

Treatment with Recombinant Human Insulin-Like Growth Factor (rhIGF)-I/rhIGF Binding Protein-3 Complex Improves Metabolic Control in Subjects with Severe Insulin Resistance

Regan, Fiona M., Williams, Rachel M., McDonald, Anna, Umpleby, A. Margot, Acerini, Carlo L., O'Rahilly, Stephen, Hovorka, Roman, Semple, Robert K., Dunger, David B.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 277 KB

english, 2010

93

Serum Ghrelin Levels Are Inversely Correlated with Body Mass Index, Age, and Insulin Concentrations in Normal Children and Are Markedly Increased in Prader-Willi Syndrome

Haqq, Andrea M., Farooqi, I. Sadaf, O’Rahilly, Stephen, Stadler, Diane D., Rosenfeld, Ron G., Pratt, Katherine L., LaFranchi, Stephen H., Purnell, Jonathan Q.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

94

Phenotypic and Genetic Heterogeneity in Congenital Generalized Lipodystrophy

Agarwal, Anil K., Simha, Vinaya, Oral, Elif Arioglu, Moran, Stephanie A., Gorden, Phillip, O’Rahilly, Stephen, Zaidi, Zohra, Gurakan, Figen, Arslanian, Silva A., Klar, Aharon, Ricker, Alyne, White, Ne

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

95

Impaired Processing of Prohormones Associated with Abnormalities of Glucose Homeostasis and Adrenal Function

O'Rahilly, Stephen, Gray, Helen, Humphreys, Phillippa J., Krook, Anna, Polonsky, Kenneth S., White, Anne, Gibson, Sarah, Taylor, Kevin, Carr, Colin

Journal:

Boston Medical and Surgical Journal

Year:

1995

Language:

english

File:

PDF, 111 KB

english, 1995

96

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

Talukder, Md. Mesbah Uddin, Sim, M.F. Michelle, O'Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.

Journal:

Molecular Metabolism

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

97

Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency

Corander, Marcus P., Rimmington, Debra, Challis, Benjamin G., O'Rahilly, Stephen, Coll, Anthony P.

Journal:

Year:

2011

Language:

english

File:

PDF, 579 KB

english, 2011

98

Functional Characterization of Naturally Occurring Pathogenic Mutations in the Human Leptin Receptor

Kimber, Wendy, Peelman, Frank, Prieur, Xavier, Wangensteen, Teresia, O'Rahilly, Stephen, Tavernier, Jan, Farooqi, I. Sadaf

Journal:

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

99

Mutations in the Amino-Terminal Region of Proopiomelanocortin ( POMC ) in Patients with Early-Onset Obesity Impair POMC Sorting to the Regulated Secretory Pathway

Creemers, John W. M., Lee, Yung Seng, Oliver, Robert L., Bahceci, Mithat, Tuzcu, Alpaslan, Gokalp, Deniz, Keogh, Julia, Herber, Stefan, White, Anne, O'Rahilly, Stephen, Farooqi, I. Sadaf

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 248 KB

english, 2008

100

A Comparative Study of the Central Effects of Specific Proopiomelancortin (POMC)-Derived Melanocortin Peptides on Food Intake and Body Weight in Pomc Null Mice

Tung, Y. C. Loraine, Piper, Sarah J., Yeung, Debra, O’Rahilly, Stephen, Coll, Anthony P.

Journal:

Year:

2006

Language:

english

File:

PDF, 378 KB

english, 2006