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1

The dual role of fibulins in tumorigenesis

Alvaro J. Obaya, Susana Rua, Angela Moncada-Pazos, Santiago Cal

Journal:

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

2

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 ||

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 9.93 MB

english, 2018

3

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Beyond the Proteolytic Activity: Examining the Functional Relevance of the Ancillary Domains Using Tri-Dimensional (3D) Spheroid Invasion Assay

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 683 KB

english, 2018

4

The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities

Angela Moncada-Pazos, Alvaro J. Obaya, Cristina G. Viloria, Carlos López-Otín, Santiago Cal

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

5

Accelerated ageing: from mechanism to therapy through animal models

Fernando G. Osorio, Álvaro J. Obaya, Carlos López-Otín, José M. P. Freije

Journal:

Transgenic Research

Year:

2009

Language:

english

File:

PDF, 321 KB

english, 2009

6

Interaction of GTP with proteins during the cell cycle of Streptomyces coelicolor

Alvaro J. Obaya, José Guijarro

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 437 KB

english, 1996

7

Mysterious liaisons: the relationship between c-Myc and the cell cycle

Obaya, Alvaro J, Mateyak, Maria K, Sedivy, John M

Journal:

Year:

1999

Language:

english

File:

PDF, 469 KB

english, 1999

8

Interaction of GTP with proteins during the cell cycle of Streptomyces coelicolor

Alvaro J. Obaya, José Guijarro

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 460 KB

english, 1996

9

A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer

Covadonga Huidobro, Rocío G. Urdinguio, Ramón María Rodríguez, Cristina Mangas, Vincenzo Calvanese, Pablo Martínez-Camblor, Cecilia Ferrero, Adolfo Parra-Blanco, Luis Rodrigo, Álvaro J. Obaya, Laura S

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.68 MB

english, 2012

10

Molecular cloning and initial characterization of three novel human sulfatases

Alvaro J. Obaya

Journal:

Year:

2006

Language:

english

File:

PDF, 808 KB

english, 2006

11

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains

Santiago Cal, Alvaro J Obaya, Marı́a Llamazares, Cecilia Garabaya, Vı́ctor Quesada, Carlos López-Otı́n

Journal:

Year:

2002

Language:

english

File:

PDF, 1.36 MB

english, 2002

12

Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer

Ester Lara, Vincenzo Calvanese, Covadonga Huidobro, Agustin F Fernández, Ángela Moncada-Pazos, Álvaro J Obaya, Oscar Aguilera, José Manuel González-Sancho, Laura Sánchez, Aurora Astudillo, Alberto Muñ

Journal:

Molecular Cancer

Year:

2010

Language:

english

File:

PDF, 1.00 MB

english, 2010

13

Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas

Fanjul-Fernández, Miriam, Quesada, Víctor, Cabanillas, Rubén, Cadiñanos, Juan, Fontanil, Tania, Obaya, Álvaro, Ramsay, Andrew J., Llorente, José L., Astudillo, Aurora, Cal, Santiago, López-Otín, Carlo

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

14

Hypernociceptive responses following the intratibial inoculation of RM1 prostate cancer cells in mice

Llorián-Salvador, María, Pevida, Marta, Fernández-García, María Teresa, Lastra, Ana, Obaya, Álvaro, Cal, Santiago, Hidalgo, Agustín, Menéndez, Luis, Baamonde, Ana

Journal:

Year:

2015

Language:

english

File:

PDF, 2.29 MB

english, 2015

15

Plasma–Fibroblast Gel as Scaffold for Islet Transplantation

Perez-Basterrechea, Marcos, Briones, Ruben M., Alvarez-Viejo, Maria, Garcia-Perez, Eva, Esteban, Manuel M., Garcia, Veronica, Obaya, Alvaro J., Barneo, Luis, Meana, Alvaro, Otero, Jesus

Journal:

Tissue Engineering Part A

Year:

2009

Language:

english

File:

PDF, 24.08 MB

english, 2009

16

Fibulin-5 downregulates Ki-67 and inhibits proliferation and invasion of breast cancer cells

Mohamedi, Yamina, Fontanil, Tania, Solares, Laura, Garcia-Suï¿½rez, Olivia, Garcï¿½a-Piqueras, Jorge, Vega, Jose, Cal, Santiago, Obaya, Alvaro

Journal:

International Journal of Oncology

Year:

2016

Language:

english

File:

PDF, 979 KB

english, 2016

17

c-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points

Mateyak, Maria K., Obaya, Alvaro J., Sedivy, John M.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.79 MB

english, 1999

18

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Human Tumor Tissue-Based 3D In Vitro Invasion Assays

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 656 KB

english, 2018

19

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Measurement of Protease Activities Using Fluorogenic Substrates

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 384 KB

english, 2018

20

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Analysis of Enzymatic Activity of Matrix Metalloproteinase (MMP) by Collagen Zymography in Melanoma

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 303 KB

english, 2018

21

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS)

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 263 KB

english, 2018

22

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Targeting the Expression of Cathepsin B Using CRISPR/Cas9 System in Mammalian Cancer Cells

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 236 KB

english, 2018

23

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Targeting Deubiquitinases in Cancer

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 293 KB

english, 2018

24

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Analysis of Somatic DNA Methylation Alterations of Genes Encoding Cell Surface Metallopeptidases in Colorectal Cancer

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 699 KB

english, 2018

25

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || A Simple Cell-Based Assay for the Detection of Surface Protein Shedding by Rhomboid Proteases

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 251 KB

english, 2018

26

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Analysis of Invasive Activity of CAF Spheroids into Three Dimensional (3D) Collagen Matrices

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 251 KB

english, 2018

27

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Dissecting Degradomes: Analysis of Protease-Coding Genes

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 759 KB

english, 2018

28

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Generation of Highly Selective MMP Antibody Inhibitors

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 605 KB

english, 2018

29

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Strategies to Target Matrix Metalloproteinases as Therapeutic Approach in Cancer

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 635 KB

english, 2018

30

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Protease Silencing to Explore the Molecular Mechanisms of Cancer and Aging

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 340 KB

english, 2018

31

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Imaging Proteolytic Activities in Mouse Models of Cancer

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 389 KB

english, 2018

32

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Autophagy and Proteases: Basic Study of the Autophagic Flux by Western Blot

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 397 KB

english, 2018

33

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Evaluation of Tumor Vasculature Using a Syngeneic Tumor Model in Wild-Type and Genetically Modified Mice

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 512 KB

english, 2018

34

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Biotin-Chasing Assay to Evaluate uPAR Stability and Cleavage on the Surface of Cells

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 294 KB

english, 2018

35

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 323 KB

english, 2018

36

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Gel-Based Gelatin Zymography to Examine Matrix Metalloproteinase Activity in Cell Culture

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 244 KB

english, 2018

37

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Cancer Susceptibility Models in Protease-Deficient Mice

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 257 KB

english, 2018

38

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || 3D Image Analysis of the Microvasculature in Healthy and Diseased Tissues

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 989 KB

english, 2018

39

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Determination of Aconitase Activity: A Substrate of the Mitochondrial Lon Protease

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 276 KB

english, 2018

40

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Ear Sponge Assay: A Method to Investigate Angiogenesis and Lymphangiogenesis in Mice

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 483 KB

english, 2018

41

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Functional Production of Catalytic Domains of Human MMPs in Escherichia coli Periplasm

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 352 KB

english, 2018

42

[Methods in Molecular Biology] Proteases and Cancer Volume 1731 || Identification of Proteolytic Cleavage Sites of EphA2 by Membrane Type 1 Matrix Metalloproteinase on the Surface of Cancer Cells

Cal, Santiago, Obaya, Alvaro J.

Year:

2018

Language:

english

File:

PDF, 564 KB

english, 2018

43

Fibroblasts accelerate islet revascularization and improve long-term graft survival in a mouse model of subcutaneous islet transplantation

Perez-Basterrechea, Marcos, Esteban, Manuel Martinez, Alvarez-Viejo, Maria, Fontanil, Tania, Cal, Santiago, Sanchez Pitiot, Marta, Otero, Jesus, Obaya, Alvaro Jesus, Fiorina, Paolo

Journal:

Year:

2017

Language:

english

File:

PDF, 28.53 MB

english, 2017

44

Role of Periostin in Adhesion and Migration of Bone Remodeling Cells

Cobo, Teresa, Viloria, Cristina G., Solares, Laura, Fontanil, Tania, González-Chamorro, Elena, De Carlos, Félix, Cobo, Juan, Cal, Santiago, Obaya, Alvaro J., Tuukkanen, Juha

Journal:

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016

45

Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA

FONTANIL, TANIA, MOHAMEDI, YAMINA, ESTEBAN, MANUEL M., OBAYA, ALVARO J., CAL, SANTIAGO

Journal:

Oncology Reports

Year:

2014

Language:

english

File:

PDF, 412 KB

english, 2014

46

An altered gene expression profile in tyramine-exposed intestinal cell cultures supports the genotoxicity of this biogenic amine at dietary concentrations

del Rio, Beatriz, Redruello, Begoña, Ladero, Victor, Cal, Santiago, Obaya, Alvaro J., Alvarez, Miguel A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

47

ADAMTS-12 metalloprotease is necessary for normal inflammatory response.

Moncada-Pazos, Angela, Obaya, Alvaro J., Llamazares, María, Heljasvaara, Ritva, Suárez, María F., Colado, Enrique, Noël, Agnès, Cal, Santiago, López-Otín, Carlos

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 276 KB

english, 2018

48

FBLN2 (fibulin 2)

Cal, Santiago, Obaya, Alvaro J,

Journal:

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Year:

2017

Language:

english

File:

PDF, 314 KB

english, 2017

49

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells

Fontanil, Tania, Rua, Susana, Llamazares, Maria, Moncada-Pazos, Angela, Quiros, Pedro M., Garcia-Suarez, Olivia, Vega, Jose A., Sasaki, Takako, Mohamedi, Yamina, Esteban, Manuel M., Obaya, Alvaro J.,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.83 MB

english, 2014

50

New Insights into ADAMTS Metalloproteases in the Central Nervous System

Mohamedi, Yamina, Fontanil, Tania, Cobo, Teresa, Cal, Santiago, Obaya, Alvaro J.

Journal:

Year:

2020

File:

PDF, 713 KB

2020