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51

Efficacy of artesunate plus chloroquine for the treatment of uncomplicated malaria in children in Burkina Faso: a double-blind, randomized, controlled trial

Sodiomon Bienvenu Sirimai, Alfred B. Tiono, Amadou Konaté, Amidou Diarra, Francesco Castelli, Loretxu Pinoges, Kefas Mugittu, Walter R.J. Taylor, Piero L. Olliaro

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2003

Language:

english

File:

PDF, 566 KB

english, 2003

52

Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial

Gerardo Priotto, Jerome Kabakyenga, Loretxu Pinoges, Ana Ruiz, Therese Eriksson, François Coussement, Tharcise Ngambe, Walter R.J. Taylor, William Perea, Jean-Paul Guthmann, Piero Olliaro, Dominique L

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2003

Language:

english

File:

PDF, 724 KB

english, 2003

53

Comparison of three treatment regimens with liposomal amphotericin B (AmBisome®) for visceral leishmaniasis in India: a randomized dose-finding study

C.P. Thakur, A.K. Pandey, G.P. Sinha, Sobhic Roy, K. Behbehani, P. Olliaro

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1996

Language:

english

File:

PDF, 493 KB

english, 1996

54

Non-ulcerative cutaneous leishmaniasis in Honduras fails to respond to topical paromomycin

Franklin A. Neva, Carlos Ponce, Elisa Ponce, Richard Kreutzer, Farrokh Modabber, Piero Olliaro

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1997

Language:

english

File:

PDF, 1.07 MB

english, 1997

55

Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal

P. Agnamey, P. Brasseur, M. Cisse, O. Gaye, J. Dumoulin, J. Rigal, W. R. J. Taylor, P. Olliaro

Journal:

Tropical Medicine & International Health

Year:

2005

Language:

english

File:

PDF, 580 KB

english, 2005

56

Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectiveness

Kefas Mugittu, Martin Adjuik, Georges Snounou, Francine Ntoumi, Walter Taylor, Hassan Mshinda, Piero Olliaro, Hans-Peter Beck

Journal:

Tropical Medicine & International Health

Year:

2006

Language:

english

File:

PDF, 596 KB

english, 2006

57

Molecular genotyping in a malaria treatment trial in Uganda – unexpected high rate of new infections within 2 weeks after treatment

Kefas Mugittu, Gerardo Priotto, Jean-Paul Guthmann, James Kiguli, Martin Adjuik, Georges Snounou, Hans-Peter Beck, Hassan Mshinda, Piero L. Olliaro, Walter R. J. Taylor

Journal:

Tropical Medicine & International Health

Year:

2007

Language:

english

File:

PDF, 476 KB

english, 2007

58

Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment

Piero Olliaro, Loretxu Pinoges, Francesco Checchi, Michel Vaillant, Jean-Paul Guthmann

Journal:

Tropical Medicine & International Health

Year:

2008

Language:

english

File:

PDF, 154 KB

english, 2008

59

Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal

P. Brasseur, P. Agnamey, O. Gaye, M. Cisse, M. Badiane, M. Vaillant, W. R. J. Taylor, P. Olliaro

Journal:

Tropical Medicine & International Health

Year:

2009

Language:

english

File:

PDF, 229 KB

english, 2009

60

Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India

P. Olliaro, S. Sundar

Journal:

Tropical Medicine & International Health

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

61

Management of fever and malaria - policy and practice

Journal:

Tropical Medicine & International Health

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

62

Cost-effectiveness projections of single and combination therapies for visceral leishmaniasis in Bihar, India

Piero Olliaro, Sarah Darley, Ramanan Laxminarayan, Shyam Sundar

Journal:

Tropical Medicine & International Health

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

63

Health care waste management: a neglected and growing public health problem worldwide

Michael O. Harhay, Scott D. Halpern, Jason S. Harhay, Piero L. Olliaro

Journal:

Tropical Medicine & International Health

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

64

Effect of artesunate and mefloquine in combination on the Fridericia corrected QT intervals in Plasmodium falciparum infected adults from Thailand

S. Krudsood, S. Looareesuwan, P. Wilairatama, W. Leowattana, N. Tangpukdee, K. Chalermrut, S. Ramanathan, V. Navaratnam, P. Olliaro, M. Vaillant, J. R. Kiechel, W. R. J. Taylor

Journal:

Tropical Medicine & International Health

Year:

2011

Language:

english

File:

PDF, 108 KB

english, 2011

65

Standardised versus actual white cell counts in estimating thick film parasitaemia in African children under five

Piero Olliaro, Abdoulaye Djimdé, Corine Karema, Andreas Mårtensson, Jean-Louis Ndiaye, Sodiomon B. Sirima, Grant Dorsey, Julien Zwang

Journal:

Tropical Medicine & International Health

Year:

2011

Language:

english

File:

PDF, 88 KB

english, 2011

66

Leishmaniasis chemotherapy—challenges and opportunities

S. L. Croft, P. Olliaro

Journal:

Clinical Microbiology and Infection

Year:

2011

Language:

english

File:

PDF, 56 KB

english, 2011

67

The Global Portfolio of New Antimalarial Medicines Under Development

Olliaro, P, Wells, TNC

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 254 KB

english, 2009

68

Macrophage Preconditioning with Synthetic Malaria Pigment Reduces Cytokine Production via Heme Iron-Dependent Oxidative Stress

Recalcati, Stefania, Basilico, Nicoletta, Olliaro, Piero, Cairo, Gaetano, Taramelli, Donatella

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 685 KB

english, 2000

69

The Heme Moiety of Malaria Pigment (β-Hematin) Mediates the Inhibition of Nitric Oxide and Tumor Necrosis Factor-α Production by Lipopolysaccharide-Stimulated Macrophages

D. Taramelli, N. Basilico, E. Pagani, R. Grande, D. Monti, M. Ghione, P. Olliaro

Journal:

Experimental Parasitology

Year:

1995

File:

PDF, 1.14 MB

1995

70

Rifabutin for the treatment of newly-diagnosed pulmonary tuberculosis: a multinational, randomized, comparative study versus rifampicin

L.J. Gonzalez-Montaner, S. Natal, P. Yongchaiyud, P. Olliaro, E. Abbate, C. Mosca, G. Casado, M. Di Lonardo, G. Gerhart-Filho, I. Betjel, S. Ferreira-Lima, A.Pereira Narinho, R. Lopez, A. Carlos-Morei

Journal:

Tubercle and Lung Disease

Year:

1994

Language:

english

File:

PDF, 952 KB

english, 1994

71

Plasmodium berghei: dehydroepiandrosterone sulfate reverses chloroquino-resistance in experimental malaria infection; correlation with glucose 6-phosphate dehydrogenase and glutathione synthesis pathway

Innocent Safeukui, François Mangou, Denis Malvy, Philippe Vincendeau, Djavad Mossalayi, Gilbert Haumont, Remi Vatan, Piero Olliaro, Pascal Millet

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

72

Hypoxia modulates the effect of dihydroartemisinin on endothelial cells

S. D’Alessandro, N. Basilico, Y. Corbett, D. Scaccabarozzi, F. Omodeo-Salè, M. Saresella, I. Marventano, M. Vaillant, P. Olliaro, D. Taramelli

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 787 KB

english, 2011

73

Unresolved issues in anthelmintic pharmacology for helminthiases of humans

Timothy G. Geary, Katherine Woo, James S. McCarthy, Charles D. Mackenzie, John Horton, Roger K. Prichard, Nilanthi R. de Silva, Piero L. Olliaro, Janis K. Lazdins-Helds, Dirk A. Engels, Donald A. Bund

Journal:

International Journal for Parasitology

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

74

Investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) using the Frog Embryo Teratogenesis Assay-Xenopus (FETAX)

Monica Longo, Sara Zanoncelli, Paola Della Torre, Francesco Rosa, AnnaMaria Giusti, Paolo Colombo, Marco Brughera, Guy Mazué, Piero Olliaro

Journal:

Reproductive Toxicology

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

75

Embryotoxicity of artemisinin-type compounds

Monica Longo, Sara Zanoncelli, Paolo A. Colombo, Marco Brughera, Guy Mazuè, Piero Olliaro

Journal:

Reproductive Toxicology

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

76

Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle

Sara Finaurini, Nicoletta Basilico, Yolanda Corbett, Sarah D’Alessandro, Silvia Parapini, Piero Olliaro, Richard K. Haynes, Donatella Taramelli

Journal:

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

77

Prooxidant activity of β-hematin (synthetic malaria pigment) in arachidonic acid micelles and phospholipid large unilamellar vesicles

Fausta Omodeo-Salè, Diego Monti, Piero Olliaro, Donatella Taramelli

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 417 KB

english, 2001

78

An Overview of Chemotherapeutic Targets for Antimalarial Drug Discovery

Piero L. Olliaro, Yongyuth Yuthavong

Journal:

Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 633 KB

english, 1999

79

Rifabutin-containing regimens for pulmonary tuberculosis: Early assessment of treatment effectiveness

J.Gonzales Montanler, J. Shoenfelder, L. Dolfi, P. Olliaro

Journal:

Tubercle and Lung Disease

Year:

1996

Language:

english

File:

PDF, 99 KB

english, 1996

80

Possible modes of action of the artemisinin-type compounds

Piero L Olliaro, Richard K Haynes, Bernard Meunier, Yongyuth Yuthavong

Journal:

Trends in Parasitology

Year:

2001

Language:

english

File:

PDF, 55 KB

english, 2001

81

Possible modes of action of the artemisinin-type compounds

P.L. Olliaro, R.K. Haynes, B. Meunier, Y. Yuthavong

Journal:

Trends in Parasitology

Year:

2001

Language:

english

File:

PDF, 22 KB

english, 2001

82

Radical mechanism of action of the artemisinin-type compounds: Response from Olliaro et al.

Piero L. Olliaro, Richard K. Haynes, Bernard Meunier, Yongyuth Yuthavong

Journal:

Trends in Parasitology

Year:

2001

Language:

english

File:

PDF, 31 KB

english, 2001

83

Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquinevssingle and combination treatments of uncomplicated falciparum in sub-Saharan Africa

Julien Zwang, Jean-Louis Ndiaye, Abdoulaye Djimdé, Grant Dorsey, Andreas Mårtensson, Corine Karema, Piero Olliaro

Journal:

Malaria Journal

Year:

2012

Language:

english

File:

PDF, 203 KB

english, 2012

84

Intensified treatment with high dose Rifampicin and Levofloxacin compared to standard treatment for adult patients with Tuberculous Meningitis (TBM-IT): protocol for a randomized controlled trial

Dorothee Heemskerk, Jeremy Day, Tran Thi Hong Chau, Nguyen Huy Dung, Nguyen Thi Bich Yen, Nguyen Duc Bang, Laura Merson, Piero Olliaro, Thomas Pouplin, Maxine Caws, Marcel Wolbers, Jeremy Farrar

Journal:

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

85

Alternative visual displays of metaanalysis of malaria treatment trials to facilitate translation of research into policy

Piero Olliaro, Michel T. Vaillant

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2010

Language:

english

File:

PDF, 971 KB

english, 2010

86

Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin

Silvia Parapini, Nicoletta Basilico, Monica Mondani, Piero Olliaro, Donatella Taramelli, Diego Monti

Journal:

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

87

Development of NIRS method for quality control of drug combination artesunate–azithromycin for the treatment of severe malaria

Chantal Boyer, Karen Gaudin, Tina Kauss, Alexandra Gaubert, Abdelhakim Boudis, Justine Verschelden, Mickaël Franc, Julie Roussille, Jacques Boucher, Piero Olliaro, Nicholas J. White, Pascal Millet, Je

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 402 KB

english, 2012

88

Response of uncomplicated falciparum malaria to oral chloroquine and quinine in Burundi highlands

Giovanni Di Perri, Piero Olliaro, Stefano Nardi, Roberto Deganello, Benedetta Allegranzi, Stefano Bonora, Sandro Vento, Ercole Concia

Journal:

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

89

Does chloroquine really act through oxidative stress?

Diego Monti, Nicoletta Basilico, Silvia Parapini, Erica Pasini, Piero Olliaro, Donatella Taramelli

Journal:

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

90

Non-iron porphyrins inhibit β-haematin (malaria pigment) polymerisation

Nicoletta Basilico, Diego Monti, Piero Olliaro, Donatella Taramelli

Journal:

Year:

1997

Language:

english

File:

PDF, 306 KB

english, 1997

91

Macrophage populations of different origins have distinct susceptibilities to lipid peroxidation induced by β-haematin (malaria pigment)

Fausta Omodeo-Salè, Nicoletta Basilico, Marco Folini, Piero Olliaro, Donatella Taramelli

Journal:

Year:

1998

Language:

english

File:

PDF, 441 KB

english, 1998

92

Drug development output: what proportion for tropical diseases?

Patrice Trouiller, Piero L Olliaro

Journal:

Year:

1999

Language:

english

File:

PDF, 25 KB

english, 1999

93

Averting a malaria disaster

Nicholas White, François Nosten, Tran Tinh Hien, William Watkins, Piero Olliaro

Journal:

Year:

1999

Language:

english

File:

PDF, 40 KB

english, 1999

94

Ethics review and clinical trials

Michael Eddleston, Krisantha Weerasuriya, Piero Olliaro

Journal:

Year:

1998

Language:

english

File:

PDF, 48 KB

english, 1998

95

Averting a malaria disaster

NJ White, F Nosten, S Looareesuwan, WM Watkins, K Marsh, RW Snow, G Kokwaro, J Ouma, TT Hien, ME Molyneux, TE Taylor, CI Newbold, TK Ruebush II, M Danis, BM Greenwood, RM Anderson, P Olliaro

Journal:

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

96

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda

Philippe J Guerin, Piero Olliaro, Shyam Sundar, Marleen Boelaert, Simon L Croft, Philippe Desjeux, Monique K Wasunna, Anthony DM Bryceson

Journal:

The Lancet Infectious Diseases

Year:

2002

Language:

english

File:

PDF, 321 KB

english, 2002

97

Miltefosine in visceral leishmaniasis

Piero L Olliaro, Robert G Ridley, Jurgen Engel, Herbert Sindermann, Anthony DM Bryceson

Journal:

The Lancet Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

98

Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980–2004

Piero L Olliaro, Philippe J Guerin, Sibylle Gerstl, Astrid Aga Haaskjold, John-Arne Rottingen, Shyam Sundar

Journal:

The Lancet Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 1.38 MB

english, 2005

99

New Targets for Antimalarial Drug Discovery

P. OLLIARO, D. WIRTH

Journal:

Journal of Pharmacy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 525 KB

english, 1997

100

A Novel Endogenous Antimalarial: Fe(II)-Protoporphyrin IXα (Heme) Inhibits Hematin Polymerization to β-Hematin (Malaria Pigment) and Kills Malaria Parasites †

Monti, Diego, Vodopivec, Bruno, Basilico, Nicoletta, Olliaro, Piero, Taramelli, Donatella

Journal:

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

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