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51

Synthesis of 16α,19-dihydroxy-4-androstene-3,17-dione and 3β,16α,19-trihydroxy-5-androsten-17-one and their 17β-hydroxy-16-keto isomers

Mitsuteru Numazawa, Ayako Mutsumi, Mieko Ogata, Yoshio Osawa

Journal:

Year:

1987

Language:

english

File:

PDF, 650 KB

english, 1987

52

Metabolic switching patterns provide definitive evidence of substrate-specificity and delineate subtle differences in positioning at the aromatase active site [Poster 06]

Mary Fronckowiak, Yoshio Osawa

Journal:

Year:

1987

Language:

english

File:

PDF, 122 KB

english, 1987

53

Acceleration and enhancement of the hypertensinogenic action of 19-hydroxyandrostenedione by the aromatase inhibitor 19-norethisterone [Poster 21]

Hisahiko Sekihara, Keiko Yonemitsu, Fumimaro Takaku, Yoshio Osawa

Journal:

Year:

1987

Language:

english

File:

PDF, 113 KB

english, 1987

54

Synthesis of 19-hydroxy-[7-2H2]androstenedione for human metabolism studies

Ohnishi Shuhei, Kosaki Toshio, Osawa Yoshio

Journal:

Year:

1990

Language:

english

File:

PDF, 562 KB

english, 1990

55

Serum level of 19-hydroxyandrostenedione during pregnancy and at delivery determined by gas chromatography/mass spectrometry

Yoshio Osawa, Shuhei Ohnishi, Carol Yarborough, Shigeki Ohigashi, Toshio Kosaki, Masashi Hashino, Takumi Yanaihara, Tetsuya Nakayama

Journal:

Year:

1990

Language:

english

File:

PDF, 636 KB

english, 1990

56

Inhibition of aromatase activity in human placental microsomes by 13-retro-antiprogestins

Yukiko Shimizu, Carol P. Yarborough, Walter Elger, Krzysztof Chwalisz, Yoshio Osawa

Journal:

Year:

1995

Language:

english

File:

PDF, 481 KB

english, 1995

57

Preparation of an activity-inhibiting monoclonal antibody against human placental aromatase cytochrome P450

Naohiro Washida, Jo Kitawaki, Tadayoshi Higashiyama, Sei-ichi Matsui, Yoshio Osawa

Journal:

Year:

1996

Language:

english

File:

PDF, 773 KB

english, 1996

58

Presence of estrogen receptors in aromatase-immunoreactive neurons in the mouse brain

Yoshihiro Tsuruo, Kazunori Ishimura, Yoshio Osawa

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 625 KB

english, 1995

59

Relationship between uterine morphology and peripheral concentrations of sex steroid hormone in wild Japanese black bears (Ursus thibetanus japonicus)

Masako Yamane, Yoshio Yamamoto, Tsunenori Tsujimoto, Takeshi Osawa

Journal:

Animal Reproduction Science

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

60

Suppression of human cytochrome P450 aromatase activity by monoclonal and recombinant antibody fragments and identification of a stable antigenic complex

Puloma Lala, Tadayoshi Higashiyama, Mary Erman, Jennifer Griswold, Traci Wagner, Yoshio Osawa, Debashis Ghosh

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 434 KB

english, 2004

61

Immunohistochemical detection of dityrosine in lipofuscin pigments in the aged human brain

Yoji Kato, Wakako Maruyama, Makoto Naoi, Yoshio Hashizume, Toshihiko Osawa

Journal:

Year:

1998

Language:

english

File:

PDF, 171 KB

english, 1998

62

Localization and expression of steroid sulfatase in human fallopian tubes

Atsushi Yanaihara, Takumi Yanaihara, Yoshiro Toma, Yukiko Shimizu, Hiroshi Saito, Takashi Okai, Tadayoshi Higashiyama, Yoshio Osawa

Journal:

Year:

2001

Language:

english

File:

PDF, 238 KB

english, 2001

63

Preparation and characterization of the Fab and F(ab′)2 fragments of an aromatase activity-suppressing monoclonal antibody

Phillip C. Ng, Yoshio Osawa

Journal:

Year:

1997

Language:

english

File:

PDF, 581 KB

english, 1997

64

Functional characterization of 102-amino acid-deleted form of human aromatase (Δ102-aromatase)1

Yeh-Chih Kao, Tadayoshi Higashiyama, Carol Yarborough, Yoshio Osawa, Shiuan Chen

Journal:

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

65

Structure of an activity suppressing Fab fragment to cytochrome P450 aromatase: insights into the antibody–antigen interactions

Mark W Sawicki, Philip C Ng, Brian M Burkhart, Vladimir Z Pletnev, Tadayoshi Higashiyama, Yoshio Osawa, Debashis Ghosh

Journal:

Molecular Immunology

Year:

1999

Language:

english

File:

PDF, 225 KB

english, 1999

66

Dietary ginger constituents, galanals A and B, are potent apoptosis inducers in Human T lymphoma Jurkat cells

Noriyuki Miyoshi, Yoshimasa Nakamura, Yasuhiro Ueda, Masako Abe, Yoshio Ozawa, Koji Uchida, Toshihiko Osawa

Journal:

Year:

2003

Language:

english

File:

PDF, 198 KB

english, 2003

67

Acute effect of c-fos antisense oligodeoxynucleotide on hippocampal partial seizures elicited by electrical stimulation in rats

Hiroshi Katsumori, Kenji Hashimoto, Shin-ichiro Tomitaka, Makiko Osawa, Yoshio Minabe

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 440 KB

english, 1997

68

Gonadal Estrogen Profile and Immunohistochemical Localization of Steroidogenic Enzymes in the Oyster and Scallop during Sexual Maturation

Toshie Matsumoto, Makoto Osada, Yoshio Osawa, Katsuyoshi Mori

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

1997

Language:

english

File:

PDF, 429 KB

english, 1997

69

Purification, characterization and crystallization of human placental estrone/dehydroepiandrosterone sulfatase, a membrane-bound enzyme of the endoplasmic reticulum

Francisco G Hernandez-Guzman, Tadayoshi Higashiyama, Yoshio Osawa, Debashis Ghosh

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

70

Aromatization of 16α-hydroxyandrostenedione by human placental microsomes: effect of preincubation with suicide substrates of androstenedione aromatization

Mitsuteru Numazawa, Mii Tachibana, Ayako Mutsumi, Akiko Yoshimura, Yoshio Osawa

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 172 KB

english, 2002

71

Structure–function studies of aromatase and its inhibitors: a progress report

Shiuan Chen, Fangming Zhang, Mark A. Sherman, Ikuko Kijima, Michael Cho, Yate-Ching Yuan, Yoshiro Toma, Yoshio Osawa, Dujin Zhou, Elizabeth T. Eng

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

72

Diverse function of aromatase and the N-terminal sequence deleted form

Yoshio Osawa, Tadayoshi Higashiyama, Yoshiro Toma, Carol Yarborough

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1997

Language:

english

File:

PDF, 778 KB

english, 1997

73

Stereospecific synthesis of 16.alpha.-hydroxy-17-oxo steroids by controlled alkaline hydrolysis of corresponding 16-bromo-17-ketones and its reaction mechanism

Numazawa, Mitsuteru, Nagaoka, Masao, Osawa, Yoshio

Journal:

Journal of Organic Chemistry

Year:

1982

Language:

english

File:

PDF, 810 KB

english, 1982

74

Mechanistic aspects of rearrangement of 16α-hydroxy-17-keto steroids to the 17β-hydroxy-16-keto isomers

Mitsuteru Numazawa, Masao Nagaoka, Hisao Matsuzaki, Kouwa Yamashita, Sachiko Komatsu, Yoshio Osawa

Journal:

Year:

2008

Language:

english

File:

PDF, 570 KB

english, 2008

75

Rat Testicular Germ Cells and Epididymal Sperm Contain Active P450 Aromatase

LYNN JANULIS, JANICE M. BAHR, REX A. HESS, SARAH JANSSEN, YOSHIO OSAWA, Dr. DAVID BUNICK

Journal:

Journal of Andrology

Year:

1998

Language:

english

File:

PDF, 1.31 MB

english, 1998

76

Conformational studies of steroids: Correlations with biological data

William L. Duax, C.M. Weeks, D.C. Rohrer, Osawa Yoshio, M.E. Wolff

Journal:

Journal of Steroid Biochemistry

Year:

1975

Language:

english

File:

PDF, 701 KB

english, 1975

77

Metabolic fate of ethynodiol diacetate in the baboon

Masayoshi Ishihara, Yoshio Osawa, Rashad Y. Kirdani, Avery A. Sandberg

Journal:

Year:

1975

Language:

english

File:

PDF, 869 KB

english, 1975

78

A steroid structure which refutes the isolation of C(17)-C(20) rotational isomers

Charles M. Weeks, Gert J. Kruger, William L. Duax, Makino Takuo, Osawa Yoshio

Journal:

Year:

1977

Language:

english

File:

PDF, 651 KB

english, 1977

79

Improved synthesis of 16α-hydroxylated androgens: Intermediates of estriol formation in pregnancy

Numazawa Mitsuteru, Osawa Yoshio

Journal:

Year:

1978

Language:

english

File:

PDF, 473 KB

english, 1978

80

Estrogen synthetase in choriocarcinoma cell culture. stimulation by dibutyryl cyclic adenosine monophosphate and theophylline

Francis L. Bellino, Robert O. Hussa, Yoshio Osawa

Journal:

Year:

1978

Language:

english

File:

PDF, 420 KB

english, 1978

81

Androgen metabolism in sheep

Yukio Yamamoto, Ludvik Peric-Golia, Yoshio Osawa, Rashad Y. Kirdani, Avery A. Sandberg

Journal:

Year:

1978

Language:

english

File:

PDF, 809 KB

english, 1978

82

Synthesis and some reactions of 6-bromoandrogens: Potential affinity ligand and inactivator of estrogen synthetase

Mitsuteru Numazawa, Yoshio Osawa

Journal:

Year:

1979

Language:

english

File:

PDF, 762 KB

english, 1979

83

Synthesis of 16α-bromoacetoxy androgens and 17 β-bromoacetylamino-4-androsten-3-one: Potential affinity labels of human placental aromatase

Numazawa Mitsuteru, Osawa Yoshio

Journal:

Year:

1981

Language:

english

File:

PDF, 593 KB

english, 1981

84

Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor

Tommi E Vaskivuo, Kristiina Aittomäki, Mikko Anttonen, Aimo Ruokonen, Riitta Herva, Yoshio Osawa, Markku Heikinheimo, Ilpo Huhtaniemi, Juha S Tapanainen

Journal:

Fertility and Sterility

Year:

2002

Language:

english

File:

PDF, 213 KB

english, 2002

85

Studies on phenolic steroids in human subjects. XIII. A rapid assay of urinary estrogen conjugates in pregnancy

Yoshio Osawa, W. Roy Slaunwhite Jr.

Journal:

Year:

1970

Language:

english

File:

PDF, 562 KB

english, 1970

86

Steroid nitrogen compounds. I. Synthesis, structure, and properties of methyl 3α,7α-diacetoxy-11α-chloro-12α-nitro-5β-cholanoate

Yoshihisa Komeichi, Yoshio Osawa, W.L. Duax, A. Cooper

Journal:

Year:

1970

Language:

english

File:

PDF, 595 KB

english, 1970

87

Generation of high pressure homogeneous dielectric barrier discharge in air

Osawa, Naoki, Takashi, Ami, Yoshioka, Yoshio, Hanaoka, Ryoichi

Journal:

The European Physical Journal Applied Physics

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

88

Competitive product inhibition of aromatase by natural estrogens

Shimizu, Yukiko, Yarborough, Carol, Osawa, Yoshio

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 401 KB

english, 1993

89

Multiple functions of aromatase and the active site structure; aromatase is the placental estrogen 2-hydroxylase

Osawa, Yoshio, Higashiyama, Tadayoshi, Shimizu, Yukiko, Yarborough, Carol

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 951 KB

english, 1993

90

Su1646 Association of Helicobacter pylori-Related Gastroduodenal Diseases With va and CagA Genotypes in Southeast Asia

Sahara, Shu, Sugimoto, Mitsushige, Uotani, Takahiro, Nishino, Masafumi, Yamada, Mihoko Yamad Takanori, Osawa, Satoshi, Sugimoto, Ken, Furuta, Takahisa, Yamaoka, Yoshio

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 114 KB

english, 2012

91

Tobacco alkaloid derivatives as inhibitors of breast cancer aromatase

Kadohama, Nobuyuki, Shintani, Keiji, Osawa, Yoshio

Journal:

Year:

1993

Language:

english

File:

PDF, 758 KB

english, 1993

92

THE ADVICE GRATIS SYSTEM.

Kadohama, Nobuyuki, Shintani, Keiji, Osawa, Yoshio

Journal:

Year:

1853

Language:

english

File:

PDF, 410 KB

english, 1853

93

Sapienate in wax esters as an index for sebaceous gland activity

Yamamoto, Ayako, Togashi, Kyoko, Osawa, Kaoruko, Serizawa, Shigeo, Ito, Masaaki, Sato, Yoshio

Journal:

Journal of Dermatological Science

Year:

1990

Language:

english

File:

PDF, 85 KB

english, 1990

94

Kinetic properties of aromatase mutants Pro308Phe, Asp309Asn, and Asp309Ala and their interactions with aromatase inhibitors

Kadohama, Nobuyuki, Yarborough, Carol, Zhou, Dujin, Chen, Shiuan, Osawa, Yoshio

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1992

Language:

english

File:

PDF, 794 KB

english, 1992

95

Structure-function studies of human aromatase

Chen, Shiuan, Zhou, Dujin, Swiderek, Kristine M., Kadohama, Nobuyuki, Osawa, Yoshio, Hall, Peter F.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

96

Ultrastructure of the skin and lipid metabolism in Sjögren-Larsson syndrome

Osawa, Kaoruko, Togashi, Kyoko, Yamamoto, Ayako, Ito, Masaaki, Sato, Yoshio

Journal:

Journal of Dermatological Science

Year:

1991

Language:

english

File:

PDF, 124 KB

english, 1991

97

Cigarette smoking during pregnancy lowers aromatase cytochrome P-450 in the human placenta

Kitawaki, Jo, Inoue, Shigeo, Tamura, Takaya, Yamamoto, Takara, Honjo, Hideo, Higashiyama, Tadayoshi, Osawa, Yoshio, Okada, Hiroji

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 856 KB

english, 1993

98

Effect of aging on the skin surface lipids and on the water-holding capacity of the stratum corneum

Togashi, Kyoko, Yamamoto, Ayako, Osawa, Kaoruko, Serizawa, Shigeo, Ito, Masaaki, Sato, Yoshio

Journal:

Journal of Dermatological Science

Year:

1991

Language:

english

File:

PDF, 124 KB

english, 1991

99

Controlled alkaline hydrolysis of 16-bromo-17-keto steroids without ketol rearrangement and its reaction mechanism

Numazawa, Mitsuteru, Osawa, Yoshio

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 392 KB

english, 1980

100

Long-Range Spin-Spin Coupling of Protons in Isomeric 6,7-Dichloroestrone Methyl Ethers

Osawa, Yoshio., Neeman, M.

Journal:

Journal of the American Chemical Society

Year:

1963

Language:

english

File:

PDF, 392 KB

english, 1963