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51

Simple is good: yeast models of neurodegeneration

Sandra Tenreiro, Tiago Fleming Outeiro

Journal:

FEMS Yeast Research

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

52

Symposium on novel therapeutic opportunities for neurodegenerative disease

Edgar F. da Cruz e Silva, Tiago Fleming Outeiro, Odete A. B. da Cruz e Silva

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 66 KB

english, 2004

53

Interactions among α-synuclein, dopamine, and biomembranes

Jean-Christophe Rochet, Tiago Fleming Outeiro, Kelly A. Conway, Tomas T. Ding, Michael J. Volles, Hilal A. Lashuel, Robert M. Bieganski, Susan L. Lindquist, Peter T. Lansbury

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

54

Molecular genetics approaches in yeast to study amyloid diseases

Tiago Fleming Outeiro, Paul J. Muchowski

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 370 KB

english, 2004

55

Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology

Journal:

Year:

2003

Language:

english

File:

PDF, 1009 KB

english, 2003

56

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Hansen, Christian, Angot, Elodie, Bergström, Ann-Louise, Steiner, Jennifer A., Pieri, Laura, Paul, Gesine, Outeiro, Tiago F., Melki, Ronald, Kallunki, Pekka, Fog, Karina

Journal:

Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 6.16 MB

english, 2011

57

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases

Tiago Fleming Outeiro, Flaviano Giorgini

Journal:

Biotechnology Journal

Year:

2006

Language:

english

File:

PDF, 557 KB

english, 2006

58

Yeast as a model for studying human neurodegenerative disorders

Leonor Miller-Fleming, Flaviano Giorgini, Tiago F. Outeiro

Journal:

Biotechnology Journal

Year:

2008

Language:

english

File:

PDF, 357 KB

english, 2008

59

Yeast as a model for studying human neurodegenerative disorders

Leonor Miller-Fleming, Flaviano Giorgini, Tiago F. Outeiro

Journal:

Biotechnology Journal

Year:

2008

Language:

english

File:

PDF, 36 KB

english, 2008

60

Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, Antonello Mai, Tiago F. Outeiro, Aleksey G. Kazanstev

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 93 KB

english, 2012

61

Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes

Goreti Ribeiro Morais, Hugo Vicente Miranda, Isabel C. Santos, Isabel Santos, Tiago F. Outeiro, Antonio Paulo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

62

Surface integrity analysis of machined Inconel 718 over multiple length scales

Rachid M'Saoubi, Tommy Larsson, José Outeiro, Yang Guo, Sergey Suslov, Christopher Saldana, Srinivasan Chandrasekar

Journal:

CIRP Annals - Manufacturing Technology

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

63

α-Synuclein modifies huntingtin aggregation in living cells

Federico Herrera, Tiago Fleming Outeiro

Journal:

Year:

2012

Language:

english

File:

PDF, 666 KB

english, 2012

64

Mechanisms of Disease II: Cellular Protein Quality Control

Tiago Fleming Outeiro, Julie Tetzlaff

Journal:

Seminars in Pediatric Neurology

Year:

2007

Language:

english

File:

PDF, 244 KB

english, 2007

65

Zooming into protein oligomerization in neurodegeneration using BiFC

Susana A. Gonçalves, Joana E. Matos, Tiago F. Outeiro

Journal:

Trends in Biochemical Sciences

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

66

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy

Sampaio-Marques, Belém, Felgueiras, Carolina, Silva, Alexandra, Rodrigues, Márcio, Tenreiro, Sandra, Franssens, Vanessa, Reichert, Andreas S., Outeiro, Tiago F., Winderickx, Joris, Ludovico, Paula

Journal:

Year:

2012

Language:

english

File:

PDF, 2.63 MB

english, 2012

67

Considerations on the use of Neisseria meningitidis class 5 proteins as meningococcal BC vaccine components

Claudio Tavares Sacchi, Maria Cecília Outeiro Gorla, Ana Paula Silva de Lemos, Maria Cristina de Cunto Brandileone

Journal:

Year:

1995

Language:

english

File:

PDF, 1.39 MB

english, 1995

68

Relationships between terrestrial gastropod distribution and soil properties in Galicia (NW Spain)

P Ondina, J Hermida, A Outeiro, S Mato

Journal:

Applied Soil Ecology

Year:

2004

Language:

english

File:

PDF, 148 KB

english, 2004

69

Therapeutic role of sirtuins in neurodegenerative disease

Tiago Fleming Outeiro, Oldriska Marques, Aleksey Kazantsev

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2008

Language:

english

File:

PDF, 419 KB

english, 2008

70

Small heat shock proteins protect against α-synuclein-induced toxicity and aggregation

Tiago Fleming Outeiro, Jochen Klucken, Katherine E. Strathearn, Fang Liu, Paul Nguyen, Jean-Christophe Rochet, Bradley T. Hyman, Pamela J. McLean

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 1.58 MB

english, 2006

71

Pharmacological inhibition of PARP-1 reduces α-synuclein- and MPP+-induced cytotoxicity in Parkinson’s disease in vitro models

Tiago Fleming Outeiro, Tom N. Grammatopoulos, Steven Altmann, Allison Amore, David G. Standaert, Bradley T. Hyman, Aleksey G. Kazantsev

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 441 KB

english, 2007

72

Angiotensin II protects against α-synuclein toxicity and reduces protein aggregation in vitro

Tom N. Grammatopoulos, Tiago F. Outeiro, Bradley T. Hyman, David G. Standaert

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 610 KB

english, 2007

73

Geostatistical methods to study spatial variability of soil cations after a prescribed fire and rainfall

Luís Outeiro, Francesc Asperó, Xavier Úbeda

Journal:

Year:

2008

Language:

english

File:

PDF, 1.62 MB

english, 2008

74

Grain refined and basal textured surface produced by burnishing for improved corrosion performance of AZ31B Mg alloy

Z. Pu, G.-L. Song, S. Yang, J.C. Outeiro, O.W. Dillon Jr., D.A. Puleo, I.S. Jawahir

Journal:

Corrosion Science

Year:

2012

Language:

english

File:

PDF, 3.35 MB

english, 2012

75

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

Brit Mollenhauer, Valerie Cullen, Ilana Kahn, Bryan Krastins, Tiago F. Outeiro, Imelda Pepivani, Juliana Ng, Walter Schulz-Schaeffer, Hans A. Kretzschmar, Pamela J. McLean, Claudia Trenkwalder, David

Journal:

Experimental Neurology

Year:

2008

Language:

english

File:

PDF, 976 KB

english, 2008

76

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice

Susanna Kemppainen, Tomi Rantamäki, André Jerónimo-Santos, Gregoire Lavasseur, Henri Autio, Nina Karpova, Elisa Kärkkäinen, Saara Stavén, Hugo Vicente Miranda, Tiago F. Outeiro, Maria J. Diógenes, Ser

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 2.57 MB

english, 2012

77

Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice

S.C.F. Marques, R. Lemos, E. Ferreiro, M. Martins, A. de Mendonça, I. Santana, T.F. Outeiro, C.M.F. Pereira

Journal:

Year:

2012

Language:

english

File:

PDF, 788 KB

english, 2012

78

Epigenetics in neurodegeneration: A new layer of complexity

Sueli C.F. Marques, Catarina R. Oliveira, Claudia M.F. Pereira, Tiago F. Outeiro

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

79

A recombinant NH2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: a possible role for syndecan-4 proteoglycan

Marianna A Ferrari do Outeiro-Bernstein, Sara Santana Nunes, Ana Carolina Magalhães Andrade, Tercia Rodrigues Alves, Chantal Legrand, Verônica Morandi

Journal:

Year:

2002

Language:

english

File:

PDF, 2.68 MB

english, 2002

80

P3.009 Aging and neurodegeneration: common targets, common hopes

Journal:

Parkinsonism & Related Disorders

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

81

Identification and quantitative analysis of human transthyretin variants in human serum by Fourier transform ion-cyclotron resonance mass spectrometry

da Costa, G., Gomes, R., Correia, C. F., Freire, A., Monteiro, E., Martins, A., Barroso, E., Coelho, A. V., Outeiro, T. F., Ponces Freire, A., Cordeiro, C.

Journal:

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

82

Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast

Swinnen, Erwin, Büttner, Sabrina, Outeiro, Tiago F., Galas, Marie‑Christine, Madeo, Frank, Winderickx, Joris, Franssens, Vanessa

Journal:

Biochemical Society Transactions

Year:

2011

Language:

english

File:

PDF, 417 KB

english, 2011

83

Suppression of -synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context

Sancenon, V., Lee, S.-A., Patrick, C., Griffith, J., Paulino, A., Outeiro, T. F., Reggiori, F., Masliah, E., Muchowski, P. J.

Journal:

Human Molecular Genetics

Year:

2012

Language:

english

File:

PDF, 830 KB

english, 2012

84

Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice

Éva M. Szegő, Tiago F. Outeiro, Pawel Kermer, Jörg B. Schulz

Journal:

Neurobiology of Aging

Year:

2013

Language:

english

File:

PDF, 2.99 MB

english, 2013

85

The zebrafish homologue of Parkinson's disease ATP13A2 is essential for embryonic survival

Lopes da Fonseca, Tomás, Correia, Ana, Hasselaar, Wiebren, van der Linde, Herma C., Willemsen, Rob, Outeiro, Tiago Fleming

Journal:

Brain Research Bulletin

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

86

Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice

Éva M. Szegő, Ellen Gerhardt, Tiago F. Outeiro, Pawel Kermer

Journal:

Journal of the Neurological Sciences

Year:

2011

Language:

english

File:

PDF, 813 KB

english, 2011

87

Surface Integrity in Dry and Cryogenic Machining of AZ31B Mg Alloy with Varying Cutting Edge Radius Tools

Z. Pu, J.C. Outeiro, A.C. Batista, O.W. Dillon, D.A. Puleo, I.S. Jawahir

Journal:

Procedia Engineering

Year:

2011

Language:

english

File:

PDF, 549 KB

english, 2011

88

An Experimental Investigation of Residual Stresses in Hard Machining of AISI 52100 Steel

S. Caruso, D. Umbrello, J.C. Outeiro, L. Filice, F. Micari

Journal:

Procedia Engineering

Year:

2011

Language:

english

File:

PDF, 690 KB

english, 2011

89

The effects of Cryogenic Cooling on Surface Integrity in Hard Machining

D. Umbrello, Z. Pu, S. Caruso, J.C. Outeiro, A.D. Jayal, O.W. Dillon, I.S. Jawahir

Journal:

Procedia Engineering

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

90

Assessing the Subcellular Dynamics of Alpha-synuclein Using Photoactivation Microscopy

Gonçalves, Susana, Outeiro, Tiago Fleming

Journal:

Molecular Neurobiology

Year:

2013

Language:

english

File:

PDF, 787 KB

english, 2013

91

LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell models

Guerreiro, PatrÃcia Silva, Huang, Yue, Gysbers, Amanda, Cheng, Danni, Gai, Wei Ping, Outeiro, Tiago Fleming, Halliday, Glenda Margaret

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 527 KB

english, 2013

92

Structural basis of kynurenine 3-monooxygenase inhibition

Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.

Journal:

Year:

2013

Language:

english

File:

PDF, 937 KB

english, 2013

93

Heat-mediated enrichment of α-synuclein from cells and tissue for assessing post-translational modifications

Miranda, Hugo Vicente, Xiang, Wei, de Oliveira, Rita M., Simões, Tânia, Pimentel, José, Klucken, Jochen, Penque, Deborah, Outeiro, Tiago F.

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 716 KB

english, 2013

94

alpha-Synuclein and intracellular trafficking: impact on the spreading of Parkinson’s disease pathology

Eisbach, Sibylle E., Outeiro, Tiago F.

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

95

Alpha-synuclein: from secretion to dysfunction and death

Marques, O, Outeiro, T F

Journal:

Cell Death and Disease

Year:

2012

Language:

english

File:

PDF, 379 KB

english, 2012

96

Functional and structural parameters to assess the ecological status of a metal contaminated area in the tropics

Niemeyer, J.C., Nogueira, M.A., Carvalho, G.M., Cohin-De-Pinho, S.J., Outeiro, U.S., Rodrigues, G.G., da Silva, E.M., Sousa, J.P.

Journal:

Ecotoxicology and Environmental Safety

Year:

2012

Language:

english

File:

PDF, 972 KB

english, 2012

97

Importance of soil exchangeable cations and aluminium content on land snail distribution

Ondina, P., Mato, S., Hermida, J., Outeiro, A.

Journal:

Applied Soil Ecology

Year:

1998

Language:

english

File:

PDF, 163 KB

english, 1998

98

Experimental Assessment of Temperature Distribution in Three-Dimensional Cutting Process

Outeiro, J. C., Dias, A. M., Lebrun, J. L.

Journal:

Machining Science and Technology

Year:

2004

Language:

english

File:

PDF, 550 KB

english, 2004

99

Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson's disease

Faria, Cristiana, Jorge, Carla D., Borges, Nuno, Tenreiro, Sandra, Outeiro, Tiago F., Santos, Helena

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2013

Language:

english

File:

PDF, 647 KB

english, 2013

100

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

Tenreiro, Sandra, Munder, Matthias C., Alberti, Simon, Outeiro, Tiago F.

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 496 KB

english, 2013