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1

Animal models of major depression and their clinical implications

Czéh, Boldizsár, Fuchs, Eberhard, Wiborg, Ove, Simon, Mária

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2015

Language:

english

File:

PDF, 2.84 MB

english, 2015

2

Grundtvig—the Key to Danish Education?

Korsgaard, Ove, Wiborg, Susanne

Journal:

Scandinavian Journal of Educational Research

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

3

Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action

Guillaume Lucas, Vladimir V. Rymar, Jenny Du, Ouissame Mnie-Filali, Christina Bisgaard, Stella Manta, Laura Lambas-Senas, Ove Wiborg, Nasser Haddjeri, Graciela Piñeyro, Abbas F. Sadikot, Guy Debonnel

Journal:

Year:

2007

Language:

english

File:

PDF, 1008 KB

english, 2007

4

Protein biomarkers of susceptibility and resilience to stress in a rat model of depression

Palmfeldt, Johan, Henningsen, Kim, Eriksen, Stine Aistrup, Müller, Heidi K., Wiborg, Ove

Journal:

Molecular and Cellular Neuroscience

Year:

2016

Language:

english

File:

PDF, 799 KB

english, 2016

5

Binding of the Amphetamine-like 1-Phenyl-piperazine to Monoamine Transporters

Severinsen, Kasper, Kraft, Johan F., Koldsø, Heidi, Vinberg, Katrine A., Rothman, Richard B., Partilla, John S., Wiborg, Ove, Blough, Bruce, Schiøtt, Birgit, Sinning, Steffen

Journal:

ACS Chemical Neuroscience

Year:

2012

Language:

english

File:

PDF, 4.60 MB

english, 2012

6

The Two Enantiomers of Citalopram Bind to the Human Serotonin Transporter in Reversed Orientations

Koldsø, Heidi, Severinsen, Kasper, Tran, Thuy Tien, Celik, Leyla, Jensen, Henrik Helligsø, Wiborg, Ove, Schiøtt, Birgit, Sinning, Steffen

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 3.54 MB

english, 2010

7

Chronic Mild Stress–Induced Depression-Like Symptoms in Rats and Abnormalities in Catecholamine Uptake in Small Arteries

Bouzinova, Elena V., Møller-Nielsen, Nina, Boedtkjer, Donna B., Broegger, Torbjoern, Wiborg, Ove, Aalkjaer, Christian, Matchkov, Vladimir V.

Journal:

Psychosomatic Medicine

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

8

Biophysical modeling of high field diffusion MRI demonstrates micro-structural aberration in chronic mild stress rat brain

Khan, Ahmad Raza, Chuhutin, Andrey, Wiborg, Ove, Kroenke, Christopher D., Nyengaard, Jens R., Hansen, Brian, Jespersen, Sune Nørhøj

Journal:

Year:

2016

Language:

english

File:

PDF, 2.42 MB

english, 2016

9

Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression

Mai Marie Holm, Jose Luis Nieto-Gonzalez, Irina Vardya, Kim Henningsen, Magdalena Niepsuj Jayatissa, Ove Wiborg, Kimmo Jensen

Journal:

Year:

2011

Language:

english

File:

PDF, 880 KB

english, 2011

10

Synthesis, inhibition and binding of simple non-nitrogen inhibitors of monoamine transporters

Mikkel Due Petersen, Søren Valdgård Boye, Erik Holm Nielsen, Jeanette Willumsen, Steffen Sinning, Ove Wiborg, Mikael Bols

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 264 KB

english, 2007

11

QSAR studies and pharmacophore identification for arylsubstituted cycloalkenecarboxylic acid methyl esters with affinity for the human dopamine transporter

Helena S. Christensen, Søren V. Boye, Jacob Thinggaard, Steffen Sinning, Ove Wiborg, Birgit Schiøtt, Mikael Bols

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 364 KB

english, 2007

12

An extended study of dimeric phenyl tropanes

Susan Nielsen, Christian M. Pedersen, Signe Grann Hansen, Mikkel Due Petersen, Steffen Sinning, Ove Wiborg, Henrik Helligsø Jensen, Mikael Bols

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 541 KB

english, 2009

13

High dopamine transporter selectivity can be displayed by remarkably simple non-nitrogen containing inhibitors

Søren V. Boye, Fernando Ortega-Caballero, Steffen Sinning, Ove Wiborg, Henrik H. Jensen, Mikael Bols

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

14

Steady-state serum concentrations of the neuroleptic perphenazine in relation to CYP2D6 genetic polymorphism

Linnet, Kristian, Wiborg, Ove

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 751 KB

english, 1996

15

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

Ole V. Mortensen, Anders S. Kristensen, Ove Wiborg

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 684 KB

english, 2001

16

Binding of S-citalopram and paroxetine discriminates between species

Betina Elfving, Ove Wiborg

Journal:

Year:

2005

Language:

english

File:

PDF, 58 KB

english, 2005

17

Proteomic Investigation of the Ventral Rat Hippocampus Links DRP-2 to Escitalopram Treatment Resistance and SNAP to Stress Resilience in the Chronic Mild Stress Model of Depression

Christina F. Bisgaard, Magdalena N. Jayatissa, Jan J. Enghild, Connie Sanchéz, Roman Artemychyn, Ove Wiborg

Journal:

Journal of Molecular Neuroscience

Year:

2007

Language:

english

File:

PDF, 246 KB

english, 2007

18

Membrane Glycoprotein M6B Interacts with the Human Serotonin Transporter

Anja Winther Fjorback, Heidi Kaastrup Müller, Ove Wiborg

Journal:

Journal of Molecular Neuroscience

Year:

2009

Language:

english

File:

PDF, 304 KB

english, 2009

19

Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

Anders S. Kristensen, Mads B. Larsen, Laust B. Johnsen, Ove Wiborg

Journal:

European Journal of Neuroscience

Year:

2004

Language:

english

File:

PDF, 601 KB

english, 2004

20

Characterization of an allosteric citalopram-binding site at the serotonin transporter

Fenghua Chen, Mads Breum Larsen, Henrik Amtoft Neubauer, Connie Sánchez, Per Plenge, Ove Wiborg

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 170 KB

english, 2005

21

Characterisation of the zebrafish serotonin transporter functionally links TM10 to the ligand binding site

Kasper Severinsen, Steffen Sinning, Heidi Kaastrup Müller, Ove Wiborg

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 1.18 MB

english, 2008

22

Region-Selective Effects of Long-Term Lithium and Carbamazepine Administration on Cyclic AMP Levels in Rat Brain

Ove Wiborg, Tanja Krüger, Søren N. Jakobsen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1999

Language:

english

File:

PDF, 569 KB

english, 1999

23

P25α / TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity

Anja W. Fjorback, Sabrina Sundbye, Justus C. Dächsel, Steffen Sinning, Ove Wiborg, Poul H. Jensen

Journal:

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

24

Serotonin depletion decreases serotonin transporter mRNA levels in rat brain

Kristian Linnet, Karen Koed, Ove Wiborg, Niels Gregersen

Journal:

Year:

1995

Language:

english

File:

PDF, 291 KB

english, 1995

25

Discovery of Lu AA33810: A highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder

Mathivanan Packiarajan, Mohammad R. Marzabadi, Mahesh Desai, Yalei Lu, Stewart A. Noble, Wai C. Wong, Vrej Jubian, Gamini Chandrasena, Toni D. Wolinsky, Hualing Zhong, Mary W. Walker, Ove. Wiborg, Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1004 KB

english, 2011

26

Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats

M.N. Jayatissa, K. Henningsen, M.J. West, Ove Wiborg

Journal:

Year:

2009

Language:

english

File:

PDF, 695 KB

english, 2009

27

Selective effects of long-term lithium and carbamazepine administration on G-protein subunit expression in rat brain

Søren Nyboe Jakobsen, Ove Wiborg

Journal:

Year:

1998

Language:

english

File:

PDF, 478 KB

english, 1998

28

Conserved exon-intron organization in two different caerulein precursor genes of Xenopus laevis : Additional detection of an exon potentially coding for a new peptide

Reinhard VLASAK, Ove WIBORG, Klaus RICHTER, Sylvia BURGSCHWAIGER, Jens VUUST, Günther KREIL

Journal:

Year:

1987

Language:

english

File:

PDF, 602 KB

english, 1987

29

Escherichia coli elongation-factor-Tu mutants with decreased affinity for aminoacyl-tRNA

Carsten ANDERSEN, Ove WIBORG

Journal:

Year:

1994

Language:

english

File:

PDF, 701 KB

english, 1994

30

Mutation of the Conserved Gly94 and Glyl26 in Elongation Factor Tu from Escherichia Coli : Elucidation of their Structural and Functional Roles

Charlotte R. Knudsen, Inger V. H. Kjærsgård, Ove Wiborg, Brian F. C. Clark

Journal:

Year:

1995

Language:

english

File:

PDF, 827 KB

english, 1995

31

Mutation of the Conserved Gly83 and Gly94 in Escherichia Coli Elongation Factor Tu : Indication of Structural Pivots

Inger V. H. Kjærsgård, Charlotte R. Knudsen, Ove Wiborg

Journal:

Year:

1995

Language:

english

File:

PDF, 766 KB

english, 1995

32

Human ubiquitin genes: One member of the UbB gene subfamily is a tetrameric non-processed pseudogene

Jack B. Cowland, Ove Wiborg, Jens Vuust

Journal:

Year:

1988

Language:

english

File:

PDF, 469 KB

english, 1988

33

Analysis and crystallization of a 25 kDa C-terminal fragment of cloned elongation factor Ts from Escherichia coli

Søren Bøgestrand, Ove Wiborg, Søren Thirup, Jens Nyborg

Journal:

Year:

1995

Language:

english

File:

PDF, 567 KB

english, 1995

34

Cognitive deficits in the rat chronic mild stress model for depression: Relation to anhedonic-like responses

Kim Henningsen, Jesper T. Andreasen, Elena V. Bouzinova, Magdalena N. Jayatissa, Morten S. Jensen, John P. Redrobe, Ove Wiborg

Journal:

Behavioural Brain Research

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

35

Hippocampal neurogenesis increase with stereotypic behavior in mink (Neovison vison)

Jens Malmkvist, Bjarke Brix, Kim Henningsen, Ove Wiborg

Journal:

Behavioural Brain Research

Year:

2012

Language:

english

File:

PDF, 462 KB

english, 2012

36

Serotonin transporter oligomerization documented in RN46A cells and neurons by sensitized acceptor emission FRET and fluorescence lifetime imaging microscopy

Anja W. Fjorback, Patrick Pla, Heidi K. Müller, Ove Wiborg, Frédéric Saudou, Jens R. Nyengaard

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

37

Modulation of the dopamine transporter by interaction with Secretory Carrier Membrane Protein 2

Anja W. Fjorback, Heidi K. Müller, Jana Haase, Merete K. Raarup, Ove Wiborg

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 573 KB

english, 2011

38

High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions

Per Plenge, Ove Wiborg

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 255 KB

english, 2005

39

The number of granule cells in rat hippocampus is reduced after chronic mild stress and re-established after chronic escitalopram treatment

Magdalena N. Jayatissa, Christina F. Bisgaard, Mark J. West, Ove Wiborg

Journal:

Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

40

Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells

Ole V Mortensen, Mads Thomassen, Mads B Larsen, Scott R Whittemore, Ove Wiborg

Journal:

Molecular Brain Research

Year:

1999

Language:

english

File:

PDF, 917 KB

english, 1999

41

Molecular cloning, expression and characterization of a bovine serotonin transporter

Ole V Mortensen, Anders S Kristensen, Gary Rudnick, Ove Wiborg

Journal:

Molecular Brain Research

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

42

Hippocampal Cytogenesis Correlates to Escitalopram-Mediated Recovery in a Chronic Mild Stress Rat Model of Depression

Jayatissa, Magdalena N, Bisgaard, Christina, Tingström, Anders, Papp, Mariusz, Wiborg, Ove

Journal:

Neuropsychopharmacology

Year:

2006

Language:

english

File:

PDF, 293 KB

english, 2006

43

The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors

Fenghua Chen, Mads Breum Larsen, Connie Sánchez, Ove Wiborg

Journal:

European Neuropsychopharmacology

Year:

2005

Language:

english

File:

PDF, 334 KB

english, 2005

44

Synergistic antidepressant-like action of gaboxadol and escitalopram

Trine Christensen, Cécile Bétry, Ouissame Mnie-Filali, Adeline Etievant, Bjarke Ebert, Nasser Haddjeri, Ove Wiborg

Journal:

European Neuropsychopharmacology

Year:

2012

Language:

english

File:

PDF, 615 KB

english, 2012

45

Magnetic Resonance Imaging and Spectroscopy Reveal Differential Hippocampal Changes in Anhedonic and Resilient Subtypes of the Chronic Mild Stress Rat Model

Rafael Delgado y Palacios, Adriaan Campo, Kim Henningsen, Marleen Verhoye, Dirk Poot, Jouke Dijkstra, Johan Van Audekerke, Helene Benveniste, Jan Sijbers, Ove Wiborg, Annemie Van der Linden

Journal:

Biological Psychiatry

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

46

Enhanced yellow fluorescent protein photoconversion to a cyan fluorescent protein-like species is sensitive to thermal and diffusion conditions

Raarup, Merete K., Fjorback, Anja W., Jensen, Stig M. R., Müller, Heidi K., Kjærgaard, Maj M., Poulsen, Hanne, Wiborg, Ove, Nyengaard, Jens R.

Journal:

Journal of Biomedical Optics

Year:

2009

Language:

english

File:

PDF, 678 KB

english, 2009

47

Chronic mild stress for modeling anhedonia

Journal:

Cell and Tissue Research

Year:

2013

Language:

english

File:

PDF, 803 KB

english, 2013

48

Binding of Serotonin to the Human Serotonin Transporter. Molecular Modeling and Experimental Validation

Celik, Leyla, Sinning, Steffen, Severinsen, Kasper, Hansen, Carsten G., Møller, Maria S., Bols, Mikael, Wiborg, Ove, Schiøtt, Birgit

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 561 KB

english, 2008

49

Combinatorial synthesis of benztropine libraries and their evaluation as monoamine transporter inhibitors

Pedersen, Hanne, Sinning, Steffen, B�low, Anne, Wiborg, Ove, Falborg, Lise, Bols, Mikael

Journal:

Organic & Biomolecular Chemistry

Year:

2004

Language:

english

File:

PDF, 270 KB

english, 2004

50

The Two Enantiomers of Citalopram Bind to the Human Serotonin Transporter in Reversed Orientations

Koldsø, Heidi, Severinsen, Kasper, Tran, Thuy Tien, Celik, Leyla, Helligsø Jensen, Henrik, Wiborg, Ove, Sinning, Steffen, Schiøtt, Birgit

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010