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1

Nitric Oxide-Releasing Drugs : A Novel Class of Effective and Safe Therapeutic Agents

JEAN-LUC BURGAUD, ENNIO ONGINI, PIERO DEL SOLDATO

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

2

Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative

Ling Li, Giuseppe Rossoni, Anna Sparatore, Lin Chiou Lee, Piero Del Soldato, Philip Keith Moore

Journal:

Free Radical Biology and Medicine

Year:

2007

Language:

english

File:

PDF, 716 KB

english, 2007

3

Therapeutic potential of new hydrogen sulfide-releasing hybrids

Sparatore, Anna, Santus, Giancarlo, Giustarini, Daniela, Rossi, Ranieri, Del Soldato, Piero

Journal:

Expert Review of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 599 KB

english, 2011

4

Gastrointestinal-sparing anti-inflammatory drugs: The development of nitric oxide-releasing NSAIDs

John L. Wallace, Susan N. Elliott, Piero Del Soldato, Webb McKnight, Franco Sannicolo, Giuseppe Cirino

Journal:

Drug Development Research

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

5

Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026)

Kenneth J. Armour, Robert J. Van 't Hof, Katharine E. Armour, Anne C. Torbergsen, Piero Del Soldato, Stuart H. Ralston

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

6

Nitric Oxide-Donating Non-Steroidal Antiinflammatory Drugs: The Case of Nitroderivatives of Aspirin.

Valerio Chiroli, Francesca Benedini, Ennio Ongini, Piero Del Soldato

Journal:

Year:

2003

File:

PDF, 120 KB

2003

7

Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation

Moonhee Lee, Anna Sparatore, Piero Del Soldato, Edith Mcgeer, Patrick L. McGeer

Journal:

Year:

2010

Language:

english

File:

PDF, 696 KB

english, 2010

8

Plasma concentrations and pharmacokinetic parameters of nitrofenac using a simple and sensitive HPLC method

Giuseppina Benoni, Alessandra Adami, Laura Cuzzolin, Marta Terzi, Luigi Grigolini, Piero Del Soldato

Journal:

Journal of Pharmaceutical Sciences

Year:

1995

Language:

english

File:

PDF, 361 KB

english, 1995

9

New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity

Elena Perrino, Graziella Cappelletti, Valerio Tazzari, Erminio Giavini, Piero Del Soldato, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

10

New prostaglandin derivative for glaucoma treatment

Elena Perrino, Caterina Uliva, Cecilia Lanzi, Piero Del Soldato, Emanuela Masini, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

11

Aortic hyporeactivity to norepinephrine induced by lipopolysaccharide in cirrhotic rats: Beneficial effects of a non-steroidal anti-inflammatory drug coupled with a nitric oxide donor

Pascale Lefilliatre, Philippe Sogni, Viviane Bertrand, Piero Del Soldato, Dominique Pateron, Richard Moreau, Didier Lebrec

Journal:

Journal of Gastroenterology and Hepatology

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

12

The therapeutic potential of NO-NSAIDs

John L. Wallace, Piero Del Soldato

Journal:

Fundamental & Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

13

ACS6, a Hydrogen sulfide-donating derivative of sildenafil, inhibits homocysteine-induced apoptosis by preservation of mitochondrial function

Xiao-Qing Tang, Rong-Qian Chen, Yan-Kai Ren, Del Piero Soldato, Anna Sparatore, Yuan-Yuan Zhuang, Hen-Rong Fang, Chun-Yan Wang

Journal:

Medical Gas Research

Year:

2011

Language:

english

File:

PDF, 677 KB

english, 2011

14

Nitric oxide-donating aspirin (NCX

Manlio Bolla, Stefania Momi, Paolo Gresele, Piero Del Soldato

Journal:

European Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

15

Addition of Nitric Oxide Through Nitric Oxide-paracetamol Enhances Healing Rat Achilles Tendon

George A. C. Murrell, Gongyao Tang, Richard C. Appleyard, Piero del Soldato, Min-Xia Wang

Journal:

Clinical Orthopaedics and Related Research®

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

16

New aryldithiolethione derivatives as potent histone deacetylase inhibitors

Valerio Tazzari, Graziella Cappelletti, Manolo Casagrande, Elena Perrino, Luigi Renzi, Piero Del Soldato, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 287 KB

english, 2010

17

Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

Nilima Shukla, Giuseppe Rossoni, Matthew Hotston, Anna Sparatore, Piero Del Soldato, Valerio Tazzari, Raj Persad, Gianni D. Angelini, Jamie Y. Jeremy

Journal:

BJU International

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

18

Modulation of β-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures

Laura Gasparini, Laura Rusconi, Huaxi Xu, Piero Del Soldato, Ennio Ongini

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 638 KB

english, 2004

19

21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties

Mark Paul-Clark, Piero Del Soldato, Stefano Fiorucci, Roderick J Flower, Mauro Perretti

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

20

Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats

Marcelo N Muscará, Fina Lovren, Webb McKnight, Michael Dicay, Piero del Soldato, Christopher R Triggle, John L Wallace

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 186 KB

english, 2001

21

NCX4016 (NO-Aspirin) has multiple inhibitory effects in LPS-stimulated human monocytes

Pietro Minuz, Maurizio Degan, Stefania Gaino, Alessandra Meneguzzi, Valeria Zuliani, Clara Lechi Santonastaso, Piero Del Soldato, Alessandro Lechi

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 231 KB

english, 2001

22

A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway THIS ARTICLE HAS BEEN RETRACTED

Stefano Fiorucci, Elisabetta Antonelli, Andrea Mencarelli, Barbara Palazzetti, Lorena Alvarez-Miller, Marcelo Muscara, Piero Del Soldato, Laura Sanpaolo, John L Wallace, Antonio Morelli

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 612 KB

english, 2002

23

NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs

Cherry L Wainwright, Ashley M Miller, Lorraine M Work, Piero Del Soldato

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

24

NCX 4016, a nitric oxide-releasing aspirin, modulates adrenergic vasoconstriction in the perfused rat tail artery

Giuseppe Rossoni, Barbara Manfredi, Piero Del Soldato, Ferruccio Berti

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

25

Enhanced anti-inflammatory potency of a nitric oxide-releasing prednisolone derivative in the rat

Fusun Turesin, Piero Del Soldato, John L Wallace

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 199 KB

english, 2003

26

Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice THIS ARTICLE HAS BEEN RETRACTED

Stefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, Andrea Mencarelli, Silvana Farneti, Piero Del Soldato, Antonio Morelli

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

27

Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis

Eric Hyun, Manlio Bolla, Martin Steinhoff, John L Wallace, Piero Del Soldato, Nathalie Vergnolle

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

28

Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats

Gema Gaitan, F Javier Ahuir, Piero Del Soldato, Juan F Herrero

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

29

Organosulfur derivatives of the HDAC inhibitor valproic acid sensitize human lung cancer cell lines to apoptosis and to cisplatin cytotoxicity

Anna Tesei, Giovanni Brigliadori, Silvia Carloni, Francesco Fabbri, Paola Ulivi, Chiara Arienti, Anna Sparatore, Piero Del Soldato, Alice Pasini, Dino Amadori, Rosella Silvestrini, Wainer Zoli

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

30

Identification of muscarinic receptor subtype mediating colonic response to eating

Francesco Narducci, Gabrio Bassotti, Sergio Daniotti, Piero Del Soldato, Maria Antonia Pelli, Antonio Morelli

Journal:

Digestive Diseases and Sciences

Year:

1985

Language:

english

File:

PDF, 360 KB

english, 1985

31

Physiological and pharmacological features of the novel gasotransmitter: Hydrogen sulfide

Daniele Mancardi, Claudia Penna, Annalisa Merlino, Piero Del Soldato, David A. Wink, Pasquale Pagliaro

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2009

Language:

english

File:

PDF, 961 KB

english, 2009

32

NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property?

Raymond K Yeh, Jie Chen, Jennie L Williams, Mehdi Baluch, Thomas R Hundley, Raphael E Rosenbaum, Srinivas Kalala, Frank Traganos, Francesca Benardini, Piero del Soldato, Khosrow Kashfi, Basil Rigas

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

33

Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats

Giuseppe Rossoni, Barbara Manfredi, Piero Del Soldato, Gianluca Polvani, Ferruccio Berti

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 451 KB

english, 2003

34

Low doses of nitroparacetamol or dexketoprofen trometamol enhance fentanyl antinociceptive activity

Gema Gaitán, Piero Del Soldato, Juan F. Herrero

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 372 KB

english, 2003

35

NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives

Paula Zacharowski, Emma Breese, Elizabeth Wood, Piero Del Soldato, Tim Warner, Jane Mitchell

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 268 KB

english, 2005

36

Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation

Rajamanickam Baskar, Anna Sparatore, Piero Del Soldato, Philip Keith Moore

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

37

Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats

Giuseppe Rossoni, Barbara Manfredi, Valerio Tazzari, Anna Sparatore, Silvio Trivulzio, Piero Del Soldato, Ferruccio Berti

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 2.36 MB

english, 2010

38

Pharmacological profile of a novel H2S-releasing aspirin

Anna Sparatore, Elena Perrino, Valerio Tazzari, Daniela Giustarini, Ranieri Rossi, Giuseppe Rossoni, Kati Erdman, Henning Schröder, Piero Del Soldato

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 567 KB

english, 2009

39

Corrigendum to “Pharmacological profile of a novel H2S-releasing aspirin” [Free Radic. Biol. Med. 46/5 (2009) 586–592]

Anna Sparatore, Elena Perrino, Valerio Tazzari, Daniela Giustarini, Ranieri Rossi, Giuseppe Rossoni, Kati Erdmann, Henning Schröder, Piero Del Soldato

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

40

Modulation of thiol homeostasis induced by H2S-releasing aspirin

Daniela Giustarini, Piero Del Soldato, Anna Sparatore, Ranieri Rossi

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 746 KB

english, 2010

41

Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS

Beatrice Hauss-Wegrzyniak, Lauren B Willard, Piero Del Soldato, Giancarlo Pepeu, Gary L Wenk

Journal:

Year:

1999

Language:

english

File:

PDF, 2.24 MB

english, 1999

42

Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin

Stefania Momi, Michael Emerson, William Paul, Mario Leone, Anna Maria Mezzasoma, Piero Del Soldato, Clive P Page, Paolo Gresele

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 313 KB

english, 2000

43

Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons

Gary L Wenk, Kristin McGann, Andrea Mencarelli, Beatrice Hauss-Wegrzyniak, Piero Del Soldato, Stefano Fiorucci

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 666 KB

english, 2000

44

Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus

Galen M Pieper, Wolfgang Siebeneich, Cara L Olds, Christopher C Felix, Piero Del Soldato

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 311 KB

english, 2002

45

Antiproliferative Effects of Nitrosulindac on Human Colon Adenocarcinoma Cell Lines

Christian Lavagna, Jean-Luc Burgaud, Piero Del Soldato, Patrick Rampal

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 347 KB

english, 2001

46

NO–Steroids: Potent Anti-inflammatory Drugs with Bronchodilating Activity in Vitro

Dominique Tallet, Piero Del Soldato, Nicole Oudart, Jean-Luc Burgaud

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

47

Comparison of the gastric cytoprotective properties of atropine, ranitidine and PGE2 in rats

Piero Del Soldato, Diego Foschi, Luisa Varin, Sergio Daniotti

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 353 KB

english, 1984

48

Effect of nitric oxide-donating agents on human monocyte cyclooxygenase-2

Teresa Corazzi, Mario Leone, Rita Roberti, Piero Del Soldato, Paolo Gresele

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

49

NO-donating aspirin inhibits intestinal carcinogenesis in Min (APCMin/+) mice

Jennie L Williams, Khosrow Kashfi, Nengtai Ouyang, Piero del Soldato, Levy Kopelovich, Basil Rigas

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

50

ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid β-induced cell cytotoxicity

Yan-Ying Liu, Anna Sparatore, Piero Del Soldato, Jin-Song Bian

Journal:

Neurochemistry International

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011