Palzkill, Timothy G.: search on Z-Library

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51

Amino Acid Sequence Determinants of β-Lactamase Structure and Activity

Wanzhi Huang, Joseph Petrosino, Marc Hirsch, Peter S. Shenkin, Timothy Palzkill

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 780 KB

english, 1996

52

Multiple Global Suppressors of Protein Stability Defects Facilitate the Evolution of Extended-Spectrum TEM β-Lactamases

Nicholas G. Brown, Jeanine M. Pennington, Wanzhi Huang, Tulin Ayvaz, Timothy Palzkill

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010

53

Mapping protein–ligand interactions using whole genome phage display libraries

Timothy Palzkill, Wanzhi Huang, George M Weinstock

Journal:

Year:

1998

Language:

english

File:

PDF, 100 KB

english, 1998

54

Extracting information from protein sequences using random replacement mutagenesis

Palzkill, Timothy, Botstein, David

Journal:

Year:

1991

Language:

english

File:

PDF, 797 KB

english, 1991

55

The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation

Patel, Meha P, Hu, Liya, Stojanoski, Vlatko, Sankaran, Banumathi, Prasad, B. V. Venkataram, Palzkill, Timothy

Journal:

Year:

2017

Language:

english

File:

PDF, 1.82 MB

english, 2017

56

Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution

Jiang, Xiqian, Zhang, Chengwei, Chen, Jianwei, Choi, Sungwoo, Zhou, Ying, Zhao, Mingkun, Song, Xianzhou, Chen, Xi, Maletic-Savatic, Mirjana, Palzkill, Timothy Gerald, Moore, David, Wang, Meng C., Wang

Journal:

Antioxidants & Redox Signaling

Year:

2018

Language:

english

File:

PDF, 2.80 MB

english, 2018

57

The vimentin rod domain blocks P-selectin-P-selectin glycoprotein ligand 1 interactions to attenuate leukocyte adhesion to inflamed endothelium

Lam, Fong Wilson, Brown, Cameron August, Valladolid, Christian, Emebo, Dabel Cynthia, Palzkill, Timothy Gerald, Cruz, Miguel Angel, Ushio-Fukai, Masuko

Journal:

Year:

2020

File:

PDF, 1.95 MB

2020

58

The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

Jeong Joo Kim, Darren E Casteel, Gilbert Huang, Taek Hun Kwon, Ronnie Kuo Ren, Peter Zwart, Jeffrey J Headd, Nicholas Gene Brown, Dar-Chone Chow, Timothy Palzkill, Choel Kim

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

59

Analysis of the Context Dependent Sequence Requirements of Active Site Residues in the Metallo-β-lactamase IMP-1

Isabel C. Materon, Zanna Beharry, Wanzhi Huang, Carla Perez, Timothy Palzkill

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 387 KB

english, 2004

60

Extensively Drug-Resistant Pseudomonas aeruginosa ST309 Harboring Tandem Guiana Extended Spectrum β-Lactamase Enzymes: A Newly Emerging Threat in the United States

Khan, Ayesha, Tran, Truc T, Rios, Rafael, Hanson, Blake, Shropshire, William C, Sun, Zhizeng, Diaz, Lorena, Dinh, An Q, Wanger, Audrey, Ostrosky-Zeichner, Luis, Palzkill, Timothy, Arias, Cesar A, Mill

Journal:

Open Forum Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 656 KB

english, 2019

61

Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC Î²-Lactamases from Klebsiella pneumoniae Clinical Isolates

Lu, Shuo, Soeung, Victoria, Nguyen, Hoang A. T., Long, S. Wesley, Musser, James M., Palzkill, Timothy, Castanheira, Mariana

Journal:

Year:

2020

File:

PDF, 1.18 MB

2020

62

A Natural Polymorphism in β -lactamase is a Global Suppressor

Wanzhi Huang and Timothy Palzkill

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.44 MB

english, 1997

63

Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric Strain

Stojanoski, Vlatko, Adamski, Carolyn J, Hu, Liya, Mehta, Shrenik C, Sankaran, Banumathi, Zwart, Peter H., Prasad, B. V. Venkataram, Palzkill, Timothy

Journal:

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

64

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases

Palzkill, Timothy

Journal:

Frontiers in Molecular Biosciences

Year:

2018

Language:

english

File:

PDF, 2.12 MB

english, 2018

65

Extensively Drug-Resistant Pseudomonas aeruginosa ST309 Harboring Tandem Guiana Extended Spectrum β-Lactamase Enzymes: A Newly Emerging Threat in the United States

Khan, Ayesha, Tran, Truc T, Rios, Rafael, Hanson, Blake, Shropshire, William C, Sun, Zhizeng, Diaz, Lorena, Dinh, An Q, Wanger, Audrey, Ostrosky-Zeichner, Luis, Palzkill, Timothy, Arias, Cesar A, Mill

Journal:

Open Forum Infectious Diseases

Year:

2019

File:

PDF, 656 KB

2019

66

Analysis of the plasticity of location of the Arg244 positive charge within the active site of the TEM-1 β-lactamase

David C. Marciano, Nicholas G. Brown, Timothy Palzkill

Journal:

Protein Science

Year:

2009

Language:

english

File:

PDF, 352 KB

english, 2009

67

Molecular analysis of beta-lactamase structure and function

Fahd K. Majiduddin, Isabel C. Materon, Timothy G. Palzkill

Journal:

International Journal of Medical Microbiology

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

68

Deep Sequencing of Systematic Combinatorial Libraries Reveals β-Lactamase Sequence Constraints at High Resolution

Zhifeng Deng, Wanzhi Huang, Erol Bakkalbasi, Nicholas G. Brown, Carolyn J. Adamski, Kacie Rice, Donna Muzny, Richard A. Gibbs, Timothy Palzkill

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

69

2063. Extracellular Release of β-Lactamase Is Responsible for the Cefazolin Inoculum Effect (CzIE) in Methicillin-Susceptible Staphylococcus aureus

Carvajal, Lina P, Santiago, Alec, Echeverri, Aura, Rios, Rafael, Rincon, Sandra, Panesso, Diana, Diaz, Lorena, Miller, William, Sun, Zhizheng, Palzkill, Timothy, Arias, Cesar, Reyes, Jinnethe

Journal:

Open Forum Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 121 KB

english, 2018

70

Epitope mapping and use of epitope-specific antisera to characterize the VP5⁎ binding site in rotavirus SA11 NSP4

Joseph M. Hyser, Carl Q.-Y. Zeng, Zanna Beharry, Timothy Palzkill, Mary K. Estes

Journal:

Year:

2008

Language:

english

File:

PDF, 1.91 MB

english, 2008

71

Using peptide arrays to define nuclear carrier binding sites on nucleoporins

Ian Cushman, Timothy Palzkill, Mary Shannon Moore

Journal:

Year:

2006

Language:

english

File:

PDF, 444 KB

english, 2006

72

Use of the arabinose pbad promoter for tightly regulated display of proteins on bacteriophage

Wanzhi Huang, Matthew McKevitt, Timothy Palzkill

Journal:

Year:

2000

Language:

english

File:

PDF, 444 KB

english, 2000

73

Antagonism between substitutions in Î²-lactamase explains a path not taken in the evolution of bacterial drug resistance

Brown, Cameron A, Hu, Liya, Sun, Zhizeng, Patel, Meha P, Singh, Sukrit, Porter, Justin R, Sankaran, Banumathi, Prasad, B.V. Venkataram, Bowman, Gregory R, Palzkill, Timothy

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 3.88 MB

2020

74

High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing

Huang, Wanzhi, Soeung, Victoria, Boragine, David M., Hu, Liya, Prasad, B.V. Venkataram, Estes, Mary K., Atmar, Robert L., Palzkill, Timothy

Journal:

Journal of Virology

Year:

2020

File:

PDF, 8.98 MB

2020

75

Fine Mapping of the Sequence Requirements for Binding of β-Lactamase Inhibitory Protein (BLIP) to TEM-1 β-Lactamase Using a Genetic Screen for BLIP Function

Ji Yuan, Wanzhi Huang, Dar-Chone Chow, Timothy Palzkill

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.05 MB

english, 2009

76

Probing β-lactamase structure and function using random replacement mutagenesis

Timothy Palzkill, David Botstein

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1992

Language:

english

File:

PDF, 1.40 MB

english, 1992

77

Evolution of antibiotic resistance: several different amino acid substitutions in an active site loop alter the substrate profile of β-lactamase

Timothy Palzkill, Quyen-Quyen Le, K. V. Venkatachalam, Mark LaRocco, Hermes Ocera

Journal:

Molecular Microbiology

Year:

1994

Language:

english

File:

PDF, 4.96 MB

english, 1994

78

β-Lactamases: protein evolution in real time

Joseph Petrosino, Carlos Cantu III, Timothy Palzkill

Journal:

Trends in Microbiology

Year:

1998

Language:

english

File:

PDF, 506 KB

english, 1998

79

Characterization of Cross-Reactive Norovirus-Specific Monoclonal Antibodies

Kou, Baijun, Crawford, Sue E., Ajami, Nadim J., Czakó, Rita, Neill, Frederick H., Tanaka, Tomoyuki N., Kitamoto, Noritoshi, Palzkill, Timothy G., Estes, Mary K., Atmar, Robert L., Hodinka, R. L.

Journal:

Clinical and Vaccine Immunology

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

80

[Techniques in Protein Chemistry] Volume 8 || Complete mutagenesis of the gene encoding TEM-1 β-lactamase

Palzkill, Timothy

Year:

1997

Language:

english

File:

PDF, 634 KB

english, 1997

81

Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding

Kim, Jeong Joo, Casteel, Darren E., Huang, Gilbert, Kwon, Taek Hun, Ren, Ronnie Kuo, Zwart, Peter, Headd, Jeffrey J., Brown, Nicholas Gene, Chow, Dar-Chone, Palzkill, Timothy, Kim, Choel, Koch, Karl-W

Journal:

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

82

Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability

Mehta, Shrenik C., Rice, Kacie, Palzkill, Timothy, Bonomo, Robert

Journal:

Year:

2015

Language:

english

File:

PDF, 2.62 MB

english, 2015

83

Penicillin-Derived Inhibitors that Simultaneously Target both Metallo- and Serine-β-lactamases

John D. Buynak, Hansong Chen, Lakshminaryana Vogeti, Venkat Rao Gadhachanda, Christine A. Buchanan, Timothy Palzkill, Robert W. Shaw, James Spencer, Timothy R. Walsh

Journal:

Year:

2004

File:

PDF, 76 KB

2004

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