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51

Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors

Paul R. Carlier, Da-Ming Du, Yifan Han, Jing Liu, Yuan-Ping Pang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

52

Evaluation of short-tether Bis-THA AChE inhibitors. A further test of the dual binding site hypothesis

Paul R. Carlier, Yi Fan Han, Ella S.-H. Chow, Crystal P.-L. Li, Hong Wang, Thuy Xuan Lieu, Hau Sum Wong, Yuan-Ping Pang

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 174 KB

english, 1999

53

Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities

Yi Fan Han, Crystal P.-L Li, Ella Chow, Hong Wang, Yuan-Ping Pang, Paul R Carlier

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 169 KB

english, 1999

54

Rational Design of Alkylene-Linked Bis-Pyridiniumaldoximes as Improved Acetylcholinesterase Reactivators

Yuan-Ping Pang, Thomas M. Kollmeyer, Feng Hong, Jong-Cheol Lee, Pamela I. Hammond, Sharie P. Haugabouk, Stephen Brimijoin

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 295 KB

english, 2003

55

Successful molecular dynamics simulation of two zinc complexes bridged by a hydroxide in phosphotriesterase using the cationic dummy atom method

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2001

Language:

english

File:

PDF, 363 KB

english, 2001

56

Three-dimensional model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: Catalytic efficiency regulated by substrate binding

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2004

Language:

english

File:

PDF, 646 KB

english, 2004

57

3D model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: Catalytic efficiency regulated by substrate binding

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2006

Language:

english

File:

PDF, 31 KB

english, 2006

58

Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies

Yuan-Ping Pang, Alan P. Kozikowski

Journal:

Journal of Computer-Aided Molecular Design

Year:

1994

Language:

english

File:

PDF, 797 KB

english, 1994

59

Prediction of the binding site of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine in acetylcholinesterase by docking studies with the SYSDOC program

Yuan-Ping Pang, Alan P. Kozikowski

Journal:

Journal of Computer-Aided Molecular Design

Year:

1994

Language:

english

File:

PDF, 653 KB

english, 1994

60

Rational design of novel neurotensin mimetics: Discovery of a pharmacologically unprecedented agent exhibiting concentration-dependent dual effects as antagonist and full agonist

Yuan-Ping Pang, Javid Zaidi, Alan P. Kozikowski, Bernadette Cusack, Elliott Richelson

Journal:

Journal of Computer-Aided Molecular Design

Year:

1994

Language:

english

File:

PDF, 589 KB

english, 1994

61

Applications of free energy derivatives to analog design

Yuan-Ping Pang, Peter A. Kollman

Journal:

Perspectives in Drug Discovery and Design

Year:

1995

Language:

english

File:

PDF, 1.21 MB

english, 1995

62

Docking Studies on the Complexed and Uncomplexed FKBP12 Structures with Bound and Unbound Ligands: An Implication of a Conformational Selection Mechanism for Binding

Yuan-Ping Pang, Norberto D. Silva, Christopher Haydock, Franklyn G. Prendergast

Journal:

Journal of Molecular Modeling

Year:

1997

Language:

english

File:

PDF, 106 KB

english, 1997

63

Zinc′s Exclusive Tetrahedral Coordination Governed by Its Electronic Structure

Rachel R. Roe, Yuan-Ping Pang

Journal:

Journal of Molecular Modeling

Year:

1999

Language:

english

File:

PDF, 71 KB

english, 1999

64

Novel Zinc Protein Molecular Dynamics Simulations: Steps Toward Antiangiogenesis for Cancer Treatment

Journal:

Journal of Molecular Modeling

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

65

Models of Ternary Complexes for Nonpeptidic Farnesyltransferase Inhibitors: Insights into Structure-Based Screen and Design of Potential Anticancer Therapeutics

Kun Xu, Emanuele Perola, Franklyn G. Prendergast, Yuan-Ping Pang

Journal:

Journal of Molecular Modeling

Year:

1999

Language:

english

File:

PDF, 1.27 MB

english, 1999

66

AVU-decomposition method for a second-order cone programming problem

Yuan Lu, Li-ping Pang, Zun-quan Xia

Journal:

Applied Mathematics and Mechanics

Year:

2010

Language:

english

File:

PDF, 159 KB

english, 2010

67

A superlinear space decomposition algorithm for constrained nonsmooth convex program

Yuan Lu, Li-Ping Pang, Fang-Fang Guo, Zun-Quan Xia

Journal:

Journal of Computational and Applied Mathematics

Year:

2010

Language:

english

File:

PDF, 515 KB

english, 2010

68

An approximate decomposition algorithm for convex minimization

Yuan Lu, Li-Ping Pang, Xi-Jun Liang, Zun-Quan Xia

Journal:

Journal of Computational and Applied Mathematics

Year:

2010

Language:

english

File:

PDF, 320 KB

english, 2010

69

Synthesis of SBA-16 and SBA-15 mesoporous silica crystals templated with neutral block copolymer surfactants

Chun-Ling Lin, Yi-Shung Pang, Mann-Chien Chao, Bi-Chung Chen, Hong-Ping Lin, Chih-Yuan Tang, Ching-Yen Lin

Journal:

Journal of Physics and Chemistry of Solids

Year:

2008

Language:

english

File:

PDF, 801 KB

english, 2008

70

Synthesis and 2D NMR analysis of a cyclopropane containing analogue of huperzine A

Alan P. Kozikowski, Fumio Yamada, Yuan-Ping Pang

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 242 KB

english, 1992

71

A Method for Studying Knife Tool Marks on Bone

Kai-Ping Shaw, Ju-Hui Chung, Fang-Chun Chung, Bo-Yuan Tseng, Chih-Hsin Pan, Kai-Ting Yang, Chun-Pang Yang

Journal:

Journal of Forensic Sciences

Year:

2011

Language:

english

File:

PDF, 292 KB

english, 2011

72

10.1038/25322

Fernandez, Julio M., Marszalek, Piotr E., Oberhauser, Andres F., Pang, Yuan-Ping

Journal:

Year:

1998

Language:

english

File:

PDF, 1.33 MB

english, 1998

73

Structure of acetylcholinesterase complexed with the nootropic alkaloid, (–)-huperzine A

Raves, Mia L., Harel, Michal, Pang, Yuan-Ping, Silman, Israel, Kozikowski, Alan P., Sussman, Joel L.

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 825 KB

1997

74

Identification of a novel mouse p53 target gene DDA3

Lo, Pang-Kuo, Chen, Jeou-Yuan, Lo, Wan-Ching, Chen, Be-Fong, Hsin, Jin-Ping, Tang, Pi-Pei, Wang, Fung-Fang

Journal:

Year:

2000

Language:

english

File:

PDF, 362 KB

english, 2000

75

Attenuation of Ischemia-Induced Mouse Brain Injury by SAG, a Redox-Inducible Antioxidant Protein

Yang, Guo-Yuan, Pang, Li, Ge, Hai-Liang, Tan, Mingjia, Ye, Wen, Liu, Xiao-Hong, Huang, Feng-Ping, Wu, Du-Chu, Che, Xiao-Ming, Song, Ying, Wen, Rong, Sun, Yi

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2001

Language:

english

File:

PDF, 8.48 MB

english, 2001

76

Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection

Kuo-Liang Yang, Jiunn-Tat Lee, Cheng-Yoong Pang, Ting-Yi Lee, Shee-Ping Chen, Hock-Kean Liew, Shin-Yuan Chen, Tzu-Yung Chen, Py-Yu Lin

Journal:

Cellular & Molecular Biology Letters

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

77

Fluorescence detection of alkaline phosphatase activity with β-cyclodextrin-modified quantum dots

Jia, Lan, Xu, Jian-Ping, Li, Di, Pang, Shao-Peng, Fang, Yuan, Song, Zhe-Gang, Ji, Jian

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

78

Theoretical Investigation of 4,4′,6,6′-Tetra(azido)azo-1,3,5-triazine-N-oxides and the Effects of N→O Bonding on Organic Azides

Dr. Cai Qi, Prof. Ru-Bo Zhang, Dr. Xue-Jiao Zhang, Dr. Yu-Chuan Li, Dr. Yuan Wang, Prof. Si-Ping Pang

Journal:

Chemistry – An Asian Journal

Year:

2011

Language:

english

File:

PDF, 539 KB

english, 2011

79

Structure-based discovery of dengue virus protease inhibitors

Suzanne M. Tomlinson, Robert D. Malmstrom, Andrew Russo, Niklaus Mueller, Yuan-Ping Pang, Stanley J. Watowich

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 478 KB

english, 2009

80

Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates

Fredrik Ekström, Yuan-Ping Pang, Malin Boman, Elisabet Artursson, Christine Akfur, Susanne Börjegren

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 766 KB

english, 2006

81

Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: Reactivation involving flipping of the His447 ring to form a reactive Glu334–His447–oxime triad

Andreas Hörnberg, Elisabet Artursson, Rikard Wärme, Yuan-Ping Pang, Fredrik Ekström

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 599 KB

english, 2010

82

Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds

Timo Wille, Fredrik Ekström, Jong-Cheol Lee, Yuan-Ping Pang, Horst Thiermann, Franz Worek

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 409 KB

english, 2010

83

Insect-specific irreversible inhibitors of acetylcholinesterase in pests including the bed bug, the eastern yellowjacket, German and American cockroaches, and the confused flour beetle

Gregory A. Polsinelli, Sanjay K. Singh, Rajesh K. Mishra, Robert Suranyi, David W. Ragsdale, Yuan-Ping Pang, Stephen Brimijoin

Journal:

Chemico-Biological Interactions

Year:

2010

Language:

english

File:

PDF, 217 KB

english, 2010

84

A selective small-molecule inhibitor of c-Jun N-terminal kinase 1

Ke Yao, Yong-Yeon Cho, Ann M. Bode, Anuradha Vummenthala, Jewn Giew Park, Kangdong Liu, Yuan-Ping Pang, Zigang Dong

Journal:

Year:

2009

Language:

english

File:

PDF, 856 KB

english, 2009

85

A single amino acid of the human and rat neurotensin receptors (subtype 1) determining the pharmacological profile of a species-selective neurotensin agonist

Bernadette Cusack, Karen Jansen, Daniel J McCormick, Thomas Chou, Yuan-Ping Pang, Elliott Richelson

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 404 KB

english, 2000

86

Comparison of DFT, Møller–Plesset, and coupled cluster calculations of the proton dissociation energies of imidazole and N-methylacetamide in the presence of zinc(II)

Jamal El Yazal, Yuan-Ping Pang

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

87

Rather than interleukin-27, interleukin-6 expresses positive correlation with liver severity in naïve hepatitis B infection patients

Jung-Ta Kao, Hsueh-Chou Lai, Shu-Mei Tsai, Pei-Chao Lin, Po-Heng Chuang, Cheng-Ju Yu, Ken-Sheng Cheng, Wen-Pang Su, Ping-Ning Hsu, Cheng-Yuan Peng, Yi-Ying Wu

Journal:

Liver International

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

88

Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency

Chen, Chinpiao, Kozikowski, Alan P., Wood, Paul L., Reynolds, Ian J., Ball, Richard G., Pang, Yuan Ping

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 2.03 MB

english, 1992

89

Theoretical 3D Model of Histamine N-Methyltransferase: Insights into the Effects of a Genetic Polymorphism on Enzymatic Activity and Thermal Stability

Yuan-Ping Pang, Xiang-E Zheng, Richard M. Weinshilboum

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 133 KB

english, 2001

90

Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat

Li-Jun Zhou, Tao Yang, Xiao Wei, Yong Liu, Wen-Jun Xin, Yuan Chen, Rui-Ping Pang, Ying Zang, Yong-Yong Li, Xian-Guo Liu

Journal:

Brain, Behavior, and Immunity

Year:

2011

Language:

english

File:

PDF, 5.50 MB

english, 2011

91

Critical role of the FERM domain in Pyk2 stimulated glioma cell migration

Christopher A. Lipinski, Nhan L. Tran, Andrea Dooley, Yuan-Ping Pang, Carole Rohl, Jean Kloss, Zhongbo Yang, Wendy McDonough, David Craig, Michael E. Berens, Joseph C. Loftus

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 930 KB

english, 2006

92

Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors

Yu-Wei Liu, Chao-Ying Li, Jia-Lie Luo, Wen-Ming Li, Hong-Jun Fu, Yuan-Zhi Lao, Li-Jiang Liu, Yuan-Ping Pang, Donald C. Chang, Zhi-Wang Li, Robert W. Peoples, Yong-Xun Ai, Yi-Fan Han

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 848 KB

english, 2008

93

Retinal ischemic injury rescued by sodium 4-phenylbutyrate in a rat model

Yung-Yue Jeng, Nien-Ting Lin, Pen-Heng Chang, Yuan-Ping Huang, Victor Fei Pang, Chen-Hsuan Liu, Chung-Tien Lin

Journal:

Experimental Eye Research

Year:

2007

Language:

english

File:

PDF, 843 KB

english, 2007

94

Configurational Entropy in Protein–Peptide Binding:: Computational Study of Tsg101 Ubiquitin E2 Variant Domain with an HIV-Derived PTAP Nonapeptide

Benjamin J. Killian, Joslyn Yudenfreund Kravitz, Sandeep Somani, Paramita Dasgupta, Yuan-Ping Pang, Michael K. Gilson

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 2.27 MB

english, 2009

95

Inhibition by bis(7)-tacrine of native delayed rectifier and KV1.2 encoded potassium channels

Hui Nie, Wen-Jing Yu, Xiang-Yuan Li, Chun-Hua Yuan, Yuan-Ping Pang, Chao-Ying Li, Yi-Fan Han, Zhi-Wang Li

Journal:

Neuroscience Letters

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

96

Inhibition of NMDA-gated ion channels by bis(7)-tacrine: Whole-cell and single-channel studies

Yu-Wei Liu, Jia-Lie Luo, Hong Ren, Robert W. Peoples, Yong-Xun Ai, Li-Jiang Liu, Yuan-Ping Pang, Zhi-Wang Li, Yi-Fan Han, Chao-Ying Li

Journal:

Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 923 KB

english, 2008

97

Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons

Li Zhou, Yu-Wei Liu, Robert W. Peoples, Min Yang, Xiang Tian, Yong-Xun Ai, Yuan-Ping Pang, Zhi-Wang Li, Yi-Fan Han, Chao-Ying Li

Journal:

Neuropharmacology

Year:

2009

Language:

english

File:

PDF, 535 KB

english, 2009

98

Development of a Botulinum Neurotoxin animal inhalation model and evaluation of small molecule therapeutics for medical countermeasure

Nambiar Madhusoodana, Davis Jon, Pang Yuan-Ping, Shi Xuerong, Gordon Richard, Millard Charles

Journal:

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

99

Proteomics shows Hsp70 does not bind peptide sequences indiscriminately in vivo

Michael E Grossmann, Benjamin J Madden, Fan Gao, Yuan-Ping Pang, John E Carpenter, Daniel McCormick, Charles Y.F Young

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 312 KB

english, 2004

100

Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases

Yuan-Ping Pang, Kun Xu, Thomas M. Kollmeyer, Emanuele Perola, William J. McGrath, Dave T. Green, Walter F. Mangel

Journal:

Year:

2001

Language:

english

File:

PDF, 6.95 MB

english, 2001