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1

Toll-Like Receptor Responsiveness of Peripheral Blood Mononuclear Cells in Young Women with Dysmenorrhea

Evans, Susan F, Kwok, Yuen H, Solterbeck, Ann, Liu, Jiajun, Hutchinson, Mark R, Hull, M Louise, Rolan, Paul E

Journal:

Journal of Pain Research

Year:

2020

Language:

english

File:

PDF, 1.82 MB

english, 2020

2

Drug Interactions with Triptans

Journal:

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

3

Reduced Response to the Thermal Grill Illusion in Chronic Pain Patients

Sumracki, Nicole M., Buisman-Pijlman, Femke T. A., Hutchinson, Mark R., Gentgall, Melanie, Rolan, Paul

Journal:

Year:

2014

Language:

english

File:

PDF, 549 KB

english, 2014

4

A novel animal model of graded neuropathic pain: Utility to investigate mechanisms of population heterogeneity

Peter M. Grace, Mark R. Hutchinson, Jim Manavis, Andrew A. Somogyi, Paul E. Rolan

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 1015 KB

english, 2010

5

Pharmacokinetics of valsartan in patients with liver disease

Brookman, Laurence J., Rolan, Paul E., Benjamin, Irving S., Palmer, Kelvin R., Wyld, Peter J., Lloyd, Peter, Flesch, Gérard, Waldmeier, Felix, Sioufi, Antoine, Mullins, Frank

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 646 KB

english, 1997

6

Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin

Lefèvre, Gilbert, Duval, Martine, Gauron, Sonia, Brookman, Laurence J., Rolan, Paul E., Morris, Thomas M., Piraino, Anthony J., Morgan, John M., Palmisano, Maria, Close, Philippe

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 906 KB

english, 1997

7

The pharmacodynamics and pharmacokinetics of the 5HT1B/1D-agonist zolmitriptan in healthy young and elderly men and women*

Peck, Richard W., Seaber, Emma J., Dixon, Ruth M., Layton, Gary R., Weatherley, Barry C., Jackson, Stephen H.D., Rolan, Paul E., Posner, John

Journal:

Clinical Pharmacology & Therapeutics

Year:

1998

Language:

english

File:

PDF, 1.18 MB

english, 1998

8

The contribution of clinical pharmacology surrogates and models to drug development—a critical appraisal

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

9

Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects

Geraldine M. Ferron, Alain Patat, Virginia Parks, Paul Rolan, Steven M. Troy

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

10

Tucaresol increases oxygen affinity and reduces haemolysis in subjects with sickle cell anaemia

ROOPEN ARYA, PAUL E. ROLAN, RAYMOND W OOTTON, JOHN POSNER, ALASTAIR J. BELLINGHAM

Journal:

British Journal of Haematology

Year:

1996

Language:

english

File:

PDF, 349 KB

english, 1996

11

Why do we still not know whether refractive error causes headaches? Towards a framework for evidence based practice

Gael E. Gordon, Edward P. Chronicle, Paul Rolan

Journal:

Ophthalmic and Physiological Optics

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

12

Effect of mental stress on cold pain in chronic tension-type headache sufferers

Stuart Cathcart, Anthony H. Winefield, Kurt Lushington, Paul Rolan

Journal:

The Journal of Headache and Pain

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

13

Pharmacokinetic studies in migraine: What questions should physicians ask?

Journal:

Current Pain and Headache Reports

Year:

2004

Language:

english

File:

PDF, 113 KB

english, 2004

14

The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males

Maria Laura Sargentini-Maier, Paul Rolan, John Connell, Dominique Tytgat, Tom Jacobs, Etienne Pigeolet, Jean-Michel Riethuisen, Armel Stockis

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 235 KB

english, 2007

15

The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy men

Paul Rolan, Maria Laura Sargentini-Maier, Etienne Pigeolet, Armel Stockis

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 419 KB

english, 2008

16

Ibudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses

Paul Rolan, Jacqueline A. Gibbons, Lin He, Eppie Chang, Drew Jones, Matthew I. Gross, Jennifer Bahr Davidson, Laura M. Sanftner, Kirk W. Johnson

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 761 KB

english, 2008

17

A comparison of two formulations of intradermal capsaicin as models of neuropathic pain in healthy volunteers

Helena Gustafsson, Johanna Åkesson, Chai Li Lau, Desmond Williams, Lisa Miller, Sharon Yap, Paul Rolan

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 618 KB

english, 2009

18

Intradermal capsaicin as a neuropathic pain model in patients with unilateral sciatica

Verna Aykanat, Melanie Gentgall, Nancy Briggs, Desmond Williams, Sharon Yap, Paul Rolan

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 3.10 MB

english, 2012

19

Noxious Inhibition of Temporal Summation is Impaired in Chronic Tension-Type Headache

Stuart Cathcart, Anthony H. Winefield, Kurt Lushington, Paul Rolan

Journal:

Headache: The Journal of Head and Face Pain

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

20

Simultaneous investigation of indinavir nonlinear pharmacokinetics and bioavailability in healthy volunteers using stable isotope labeling technique: Study design and model-independent data analysis

Kuang C. Yeh, Julie A. Stone, Alexandra D. Carides, Paul Rolan, Eric Woolf, William D. Ju

Journal:

Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

21

Effect of cimetidine on renal and hepatic drug elimination: Studies with triamterene

Muirhead, Murray R, Somogyi, Andrew A, Rolan, Paul E, Bochner, Felix

Journal:

Clinical Pharmacology & Therapeutics

Year:

1986

Language:

english

File:

PDF, 662 KB

english, 1986

22

Current issues relating to drug safety especially with regard to the use of biomarkers: A meeting report and progress update

Paul Rolan, Meindert Danhof, Donald Stanski, Carl Peck

Journal:

European Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 222 KB

english, 2007

23

Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model

Peter M. Grace, Daniel Hurley, Daniel T. Barratt, Anna Tsykin, Linda R. Watkins, Paul E. Rolan, Mark R. Hutchinson

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 679 KB

english, 2012

24

Adoptive transfer of peripheral immune cells potentiates allodynia in a graded chronic constriction injury model of neuropathic pain

Peter M. Grace, Mark R. Hutchinson, Alan Bishop, Andrew A. Somogyi, Graham Mayrhofer, Paul E. Rolan

Journal:

Brain, Behavior, and Immunity

Year:

2011

Language:

english

File:

PDF, 802 KB

english, 2011

25

Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain

Peter M. Grace, Paul E. Rolan, Mark R. Hutchinson

Journal:

Brain, Behavior, and Immunity

Year:

2011

Language:

english

File:

PDF, 546 KB

english, 2011

26

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

Paul W Noble, Carlo Albera, Williamson Z Bradford, Ulrich Costabel, Marilyn K Glassberg, David Kardatzke, Talmadge E King Jr, Lisa Lancaster, Steven A Sahn, Javier Szwarcberg, Dominique Valeyre, Rolan

Journal:

Year:

2011

Language:

english

File:

PDF, 307 KB

english, 2011

27

Effect of citalopram on plasma levels of oral theophylline

Svend Erik Møller, Frank Larsen, Maria Pitsiu, Paul E. Rolan

Journal:

Clinical Therapeutics

Year:

2000

Language:

english

File:

PDF, 547 KB

english, 2000

28

Why do we still not know whether refractive error causes headaches? Towards a framework for evidence based practice

Gael E Gordon, Edward P Chronicle, Paul Rolan

Journal:

Ophthalmic and Physiological Optics

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

29

Pharmacokinetics of high-dose buprenorphine following single administration of sublingual tablet formulations in opioid naı̈ve healthy male volunteers under a naltrexone block

Sarah D McAleer, Richard J Mills, Torsten Polack, Tanweer Hussain, Paul E Rolan, Alan D Gibbs, Frank G.P Mullins, Ziad Hussein

Journal:

Drug and Alcohol Dependence

Year:

2003

Language:

english

File:

PDF, 548 KB

english, 2003

30

The pharmacokinetics and pharmacodynamics of single dose (R)- and (S)-warfarin administered separately and together: relationship to VKORC1 genotype

Maddison, John, Somogyi, Andrew A., Jensen, Berit P., James, Heather M., Gentgall, Melanie, Rolan, Paul E.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

31

Disposition of a Single Dose of Warfarin in Healthy Individuals after Pretreatment with Metrifonate

Dr Roland Heinig, Nicholas Kitchin, Paul Rolan

Journal:

Clinical Drug Investigation

Year:

1999

Language:

english

File:

PDF, 203 KB

english, 1999

32

Understanding the pharmacology of headache

Rolan, Paul Edward

Journal:

Current Opinion in Pharmacology

Year:

2014

Language:

english

File:

PDF, 200 KB

english, 2014

33

Low-dose endotoxin potentiates capsaicin-induced pain in man: Evidence for a pain neuroimmune connection

Hutchinson, Mark R., Buijs, Mara, Tuke, Jonathan, Kwok, Yuen Hei, Gentgall, Melanie, Williams, Desmond, Rolan, Paul

Journal:

Brain, Behavior, and Immunity

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

34

Pharmacokinetics of New Antiherpetic Agents

Journal:

Clinical Pharmacokinetics

Year:

1995

Language:

english

File:

PDF, 830 KB

english, 1995

35

Effect of brivaracetam (400 mg/day) on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive in healthy women

Stockis, Armel, Rolan, Paul

Journal:

Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

36

Estimation Procedure for a Multiple Time Series Model

Cruz, Rolan Paul K. Veron, Barrios, Erniel B.

Journal:

Communications in Statistics - Simulation and Computation

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

37

The absolute bioavailability of racemic ketamine from a novel sublingual formulation

Rolan, Paul, Lim, Stephen, Sunderland, Vivian, Liu, Yandi, Molnar, Valeria

Journal:

British Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 747 KB

english, 2014

38

Brivaracetam and carbamazepine interaction in healthy subjects and in vitro

Stockis, Armel, Chanteux, Hugues, Rosa, Maria, Rolan, Paul

Journal:

Epilepsy Research

Year:

2015

Language:

english

File:

PDF, 657 KB

english, 2015

39

Low-dose hydrocortisone replacement improves wellbeing and pain tolerance in chronic pain patients with opioid-induced hypocortisolemic responses. A pilot randomized, placebo-controlled trial

Nenke, Marni A., Haylock, Clare L., Rankin, Wayne, Inder, Warrick J., Gagliardi, Lucia, Eldridge, Crystal, Rolan, Paul, Torpy, David J.

Journal:

Psychoneuroendocrinology

Year:

2015

Language:

english

File:

PDF, 873 KB

english, 2015

40

Paradoxical topiramate-induced hyperphagia successfully treated with phentermine in a woman with migraine

Johnson, Jacinta L., Rolan, Paul E.

Journal:

Journal of Clinical Neuroscience

Year:

2015

Language:

english

File:

PDF, 184 KB

english, 2015

41

What to do about opioids for chronic noncancer pain? A perspective from Australia

Journal:

Pain Management

Year:

2011

File:

PDF, 947 KB

2011

42

What to do about opioids for chronic noncancer pain? A perspective from Australia

Journal:

Pain Management

Year:

2011

Language:

english

File:

PDF, 947 KB

english, 2011

43

Interview: A clinical pharmacologist’s journey in pain research and treatment

Journal:

Pain Management

Year:

2012

Language:

english

File:

PDF, 784 KB

english, 2012

44

SAFETY AND EFFICACY OF PRO ANP 31-67 IN CARDIORENAL SYNDROME: A FIRST-IN-HUMAN TRIAL

Delacroix, Sinny, Chokka, Ramesh, Nelson, Adam, Sidharta, Samuel, Teo, Karen, Tuke, Jonathan, Upton, Richard, Rolan, Paul E., Worthley, Stephen

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 349 KB

english, 2016

45

Lack of Effect of Citalopram on the Steady-State Pharmacokinetics of Carbamazepine in Healthy Male Subjects

Møller, Svend Erik, Larsen, Frank, Khan, Azhar Z., Rolan, Paul E.

Journal:

Journal of Clinical Psychopharmacology

Year:

2001

Language:

english

File:

PDF, 107 KB

english, 2001

46

Glial Attenuation With Ibudilast in the Treatment of Medication Overuse Headache: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial of Efficacy and Safety

Johnson, Jacinta L., Kwok, Yuen H., Sumracki, Nicole M., Swift, James E., Hutchinson, Mark R., Johnson, Kirk, Williams, Desmond B., Tuke, Jonathon, Rolan, Paul E.

Journal:

Headache: The Journal of Head and Face Pain

Year:

2015

Language:

english

File:

PDF, 302 KB

english, 2015

47

A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy-naïve Pancreatic Adenocarcinoma

Cohen, Steven J., Zalupski, Mark M., Conkling, Paul, Nugent, Francis, Ma, Wen Wee, Modiano, Manuel, Pascual, Rolan, Lee, Fa Chyi, Wong, Lucas, Hersh, Evan

Journal:

American Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 125 KB

english, 2015

48

Stem cell therapy clinical research: A regulatory conundrum for academia

Nagpal, Anjali, Juttner, Chris, Hamilton-Bruce, Monica Anne, Rolan, Paul, Koblar, Simon A.

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 1.99 MB

english, 2016

49

TLR 2 and 4 Responsiveness from Isolated Peripheral Blood Mononuclear Cells from Rats and Humans as Potential Chronic Pain Biomarkers

Kwok, Yuen H., Tuke, Jonathan, Nicotra, Lauren L., Grace, Peter M., Rolan, Paul E., Hutchinson, Mark R., Price, Theodore John

Journal:

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

50

First-In-Human, Double-Blind, Placebo-Controlled, Randomized, Dose-Escalation Study of BG00010, a Glial Cell Line-Derived Neurotrophic Factor Family Member, in Subjects with Unilateral Sciatica

Rolan, Paul E., O’Neill, Gilmore, Versage, Eve, Rana, Jitesh, Tang, Yongqiang, Galluppi, Gerald, Aycardi, Ernesto, Sterling, Michele

Journal:

Year:

2015

Language:

english

File:

PDF, 3.86 MB

english, 2015