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51

Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Physical Review E

Year:

2009

Language:

english

File:

PDF, 626 KB

english, 2009

52

Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA

Smolen, Josef S., Boers, Maarten, Abadie, Eric C., Breedveld, Ferdinand C., Emery, Paul, Bardin, Thomas, Goel, Niti, Ethgen, Dominique J., Avouac, Bernard P., Dere, Willard H., Durez, Patrick, Matucci

Journal:

Current Medical Research and Opinion

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

53

Reduced Models of the Circadian Oscillators in Neurospora crassa and Drosophila melanogaster Illustrate Mechanistic Similarities

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Omics A Journal of Integrative Biology

Year:

2003

Language:

english

File:

PDF, 813 KB

english, 2003

54

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis

Karpus, Olga N, Kiener, Hans P, Niederreiter, Birgit, Yilmaz-Elis, A, van der Kaa, Jos, Ramaglia, Valeria, Arens, Ramon, Smolen, Josef S, Botto, Marina, Tak, Paul P, Verbeek, J, Hamann, Jörg

Journal:

Arthritis Research & Therapy

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

55

Molecular Constraints on Synaptic Tagging and Maintenance of Long-Term Potentiation: A Predictive Model

Smolen, Paul, Baxter, Douglas A., Byrne, John H., Morrison, Abigail

Journal:

PLoS Computational Biology

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

56

Simulations suggest pharmacological methods for rescuing long-term potentiation

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Journal of Theoretical Biology

Year:

2014

Language:

english

File:

PDF, 506 KB

english, 2014

57

Reliability of patient-reported outcomes in rheumatoid arthritis patients: an observational prospective study

Studenic, Paul, Stamm, Tanja, Smolen, Josef S., Aletaha, Daniel

Journal:

Year:

2015

Language:

english

File:

PDF, 89 KB

english, 2015

58

Controlled release of fibrin matrix-conjugated platelet derived growth factor improves ischemic tissue regeneration by functional angiogenesis

Mittermayr, Rainer, Slezak, Paul, Haffner, Nicolas, Smolen, Daniel, Hartinger, Joachim, Hofmann, Anna, Schense, Jason, Spazierer, Daniel, Gampfer, Jörg, Goppelt, Andreas, Redl, Heinz

Journal:

Acta Biomaterialia

Year:

2015

Language:

english

File:

PDF, 2.47 MB

english, 2015

59

New York City Department of Health, 100 Years || The Radiation Control Program

Hanson Blatz, M. B. Heller, S. M. Kamholz, D. E. Lynch, I. R. Paul, B. S. Reich and M. Smolens

Journal:

Public Health Reports (1896-1970)

Year:

1966

Language:

english

File:

PDF, 758 KB

english, 1966

60

Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

Haffner, Nicolas, Antonic, Vlado, Smolen, Daniel, Slezak, Paul, Schaden, Wolfgang, Mittermayr, Rainer, Stojadinovic, Alexander

Journal:

Year:

2016

Language:

english

File:

PDF, 582 KB

english, 2016

61

SPIE Proceedings [SPIE Optics East 2006 - Boston, MA (Sunday 1 October 2006)] Optical Methods in the Life Sciences - Interstitial doppler OCT monitoring of microvascular shutdown during photodynamic therapy in a Dunning prostate model: irradiance rate dependences

Standish, Beau A., Analoui, Mostafa, Belyanin, Alexey A., Jin, Xiao, Smolen, Jurek, Drezek, Rebekah A., Gmachl, Claire F., Mariampillai, Adrian, Munce, Nigel R., Robinson, J. Paul, Vitkin, I. A., Yang

Year:

2006

Language:

english

File:

PDF, 1.39 MB

english, 2006

62

Effect of adalimumab on the work-related outcomes scores in patients with early rheumatoid arthritis receiving methotrexate

Emery, Paul, Smolen, Josef S., Ganguli, Arijit, Meerwein, Sebastian, Bao, Yanjun, Kupper, Hartmut, Chen, Naijun, Kavanaugh, Arthur

Journal:

Year:

2016

Language:

english

File:

PDF, 260 KB

english, 2016

63

Bursting Electrical Activity in Pancreatic β Cells Caused by Ca2+-and Voltage-Inactivated Ca2+Channels

Joel Keizer and Paul Smolen

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

64

Computational model of a positive BDNF feedback loop in hippocampal neurons following inhibitory avoidance training

Zhang, Yili, Smolen, Paul, Alberini, Cristina M., Baxter, Douglas A., Byrne, John H.

Journal:

Learning & Memory

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

65

Different Rating of Global Rheumatoid Arthritis (RA) Disease Activity in Multimorbid Patients with RA

Radner, Helga, Yoshida, Kazuki, Tedeschi, Sara, Studenic, Paul, Frits, Michelle, Iannaccone, Christine, Shadick, Nancy A., Weinblatt, Michael, Aletaha, Daniel, Smolen, Josef S., Solomon, Daniel H.

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 877 KB

english, 2016

66

Patient-reported outcomes from a randomised phase III study of baricitinib in patients with rheumatoid arthritis and an inadequate response to biological agents (RA-BEACON)

Smolen, Josef S, Kremer, Joel M, Gaich, Carol L, DeLozier, Amy M, Schlichting, Douglas E, Xie, Li, Stoykov, Ivaylo, Rooney, Terence, Bird, Paul, Sánchez Bursón, Juan Miguel, Genovese, Mark C, Combe, B

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 949 KB

english, 2017

67

The changing landscape of biosimilars in rheumatology

Dörner, Thomas, Strand, Vibeke, Cornes, Paul, Gonçalves, João, Gulácsi, László, Kay, Jonathan, Kvien, Tore K, Smolen, Josef, Tanaka, Yoshiya, Burmester, Gerd R

Journal:

Annals of the Rheumatic Diseases

Year:

2016

Language:

english

File:

PDF, 476 KB

english, 2016

68

Clinical meaning and implications of serum hemoglobin levels in patients with rheumatoid arthritis

Padjen, Ivan, Öhler, Leopold, Studenic, Paul, Woodworth, Thasia, Smolen, Josef, Aletaha, Daniel

Journal:

Seminars in Arthritis and Rheumatism

Year:

2017

Language:

english

File:

PDF, 873 KB

english, 2017

69

Superior long-term synaptic memory induced by combining dual pharmacological activation of PKA and ERK with an enhanced training protocol

Liu, Rong-Yu, Neveu, Curtis, Smolen, Paul, Cleary, Leonard J., Byrne, John H.

Journal:

Learning & Memory

Year:

2017

Language:

english

File:

PDF, 537 KB

english, 2017

70

Health Problems During the First Year of Life in Infants Born to Adolescent Mothers

SMOLEN, PAUL, MILLER, CHARLENE, OʼNEAL, RUTH, LAWLESS, MICHAEL R.

Journal:

Southern Medical Journal

Year:

1984

File:

PDF, 333 KB

1984

71

[BMJ Publishing Group Ltd and European League Against Rheumatism 37th European Workshop for Rheumatology Research 2–4 March 2017 Athens, Greece - ()] Autoimmune inflammation - 08.28 The prognostic value of iga autoantibodies (rheumatoid factor and acpa) for prediction of the therapeutic response to anti-tnf therapy in patients with rheumatoid arthritis

Sieghart, Daniela, Studenic, Paul, Alasti, Farideh, Horn, Thomas, Haslacher, Helmut, Aletaha, Daniel, Smolen, Josef, Steiner, Günter

Language:

english

File:

PDF, 66 KB

english

72

Achieving comprehensive disease control in patients with early and established rheumatoid arthritis treated with adalimumab plus methotrexate versus methotrexate alone

Keystone, Edward C, Breedveld, Ferdinand C, Heijde, Désirée van der, van Vollenhoven, Ronald F, Emery, Paul, Smolen, Josef S, Sainsbury, Iain, Florentinus, Stefan, Kupper, Hartmut, Chen, Kun, Kavanaug

Journal:

Year:

2017

Language:

english

File:

PDF, 1.78 MB

english, 2017

73

Testing treat-to-target outcomes with initial methotrexate monotherapy compared with initial tumour necrosis factor inhibitor (adalimumab) plus methotrexate in early rheumatoid arthritis

Kavanaugh, Arthur, van Vollenhoven, Ronald, Fleischmann, Roy M, Emery, Paul, Sainsbury, Iain, Florentinus, Stefan, Chen, Su, Guérette, Benoît, Kupper, Hartmut, Smolen, Josef S

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

74

Targeted inhibition of Janus kinases abates interfon gamma-induced invasive behaviour of fibroblast-like synoviocytes

Karonitsch, Thomas, Beckmann, Denise, Dalwigk, Karolina, Niederreiter, Birgit, Studenic, Paul, Byrne, Ruth A, Holinka, Johannes, Sevelda, Florian, Korb-Pap, Adelheid, Steiner, Günter, Smolen, Josef S,

Journal:

Year:

2017

Language:

english

File:

PDF, 385 KB

english, 2017

75

Trends and Associations with PrEP Prescription Among 602 New York City (NYC) Ambulatory Care Practices, 2014–2016

Salcuni, Paul, Smolen, Jenny, Jain, Sachin, Myers, Julie, Edelstein, Zoe

Journal:

Open Forum Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 772 KB

english, 2017

76

A Model of Late Long-Term Potentiation Simulates Aspects of Memory Maintenance

Smolen, Paul, Tsien, Joe

Journal:

Year:

2007

Language:

english

File:

PDF, 712 KB

english, 2007

77

Modeling Maintenance of Long-Term Potentiation in Clustered Synapses: Long-Term Memory without Bistability

Journal:

Neural Plasticity

Year:

2015

Language:

english

File:

PDF, 1.83 MB

english, 2015

78

Determination of Autoantibody Isotypes Increases the Sensitivity of Serodiagnostics in Rheumatoid Arthritis

Sieghart, Daniela, Platzer, Alexander, Studenic, Paul, Alasti, Farideh, Grundhuber, Maresa, Swiniarski, Sascha, Horn, Thomas, Haslacher, Helmuth, Blüml, Stephan, Smolen, Josef, Steiner, Günter

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 791 KB

english, 2018

79

Effects of macromolecular transport and stochastic fluctuations on dynamics of genetic regulatory systems

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

American journal of physiology. Cell physiology

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

80

Paradoxical LTP maintenance with inhibition of protein synthesis and the proteasome suggests a novel protein synthesis requirement for early LTP reversal

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Journal of Theoretical Biology

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

81

Support of Progress in Clinical Neurology by Models of Genetic Regulation

Smolen, Paul, Byrne, John H.

Journal:

Archives of Neurology

Year:

2003

Language:

english

File:

PDF, 84 KB

english, 2003

82

Modeling Circadian Oscillations with Interlocking Positive and Negative Feedback Loops

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 434 KB

english, 2001

83

Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems

Smolen, Paul, Baxter, Douglas A., Byrne, John H.

Journal:

American journal of physiology. Cell physiology

Year:

1998

Language:

english

File:

PDF, 257 KB

english, 1998

84

I do not want to suppress the natural process of inflammation: new insights on factors associated with non-adherence in rheumatoid arthritis

Ritschl, Valentin, Lackner, Angelika, Boström, Carina, Mosor, Erika, Lehner, Michaela, Omara, Maisa, Ramos, Romualdo, Studenic, Paul, Smolen, Josef Sebastian, Stamm, Tanja Alexandra

Journal:

Arthritis Research & Therapy

Year:

2018

Language:

english

File:

PDF, 973 KB

english, 2018

85

219 Safety summary results of baricitinib focusing on serious infections events and preselected comorbidities

Combe, Bernard, Balsa, Alejandro, Winthrop, Kevin, Tony, Hans-Peter, Genovese, Mark C, Harigai, Masayoshi, Smolen, Josef S, Emery, Paul, Dudler, Jean, Hall, Stephen, Zerbini, Cristiano A, Van Den Bosc

Journal:

Year:

2018

Language:

english

File:

PDF, 64 KB

english, 2018

86

e48 Effects of baricitinib on haematological laboratory parameters in patients with rheumatoid arthritis

Huizinga, Thomas W, Kay, Jonathan, Harigai, Masayoshi, Keystone, Edward, Smolen, Josef, Rosas, José, Emery, Paul, Hall, Stephen, van den Bosch, Filip, Schienberg, Morton, Dudler, Jean, Liao, Ran, Mesz

Journal:

Year:

2018

Language:

english

File:

PDF, 65 KB

english, 2018

87

From Molecules to Networks || Modeling and Analysis of Intracellular Signaling Pathways

Smolen, Paul D.

Year:

2014

Language:

english

File:

PDF, 2.14 MB

english, 2014

88

The effect of deep or sustained remission on maintenance of remission after dose reduction or withdrawal of etanercept in patients with rheumatoid arthritis

Tanaka, Yoshiya, Smolen, Josef S., Jones, Heather, Szumski, Annette, Marshall, Lisa, Emery, Paul

Journal:

Arthritis Research & Therapy

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

89

Relative Impact of Pain and Fatigue on Work Productivity in Patients with Rheumatoid Arthritis from the RA-BEAM Baricitinib Trial

Michaud, Kaleb, Pope, Janet E., Emery, Paul, Zhu, Baojin, Gaich, Carol L., DeLozier, Amy M., Zhang, Xiang, Dickson, Christina L., Smolen, Josef S.

Journal:

Rheumatology and Therapy

Year:

2019

File:

PDF, 1.21 MB

2019

90

60. Work Related Outcomes in Early Rheumatoid Arthritis Patients with Elevated Risk of Employment Loss: Results from Two Randomized Clinical Trials (Optima and Prowd) on the Effect of Adalimumab and Methotrexate Combination Therapy Versus Methotrexate Monotherapy Over 6 Months of Treatment

Emery, Paul, Smolen, Josef, Ganguli, Arijit, Meerwein, Sebastian, Bao, Yanjun, Kupper, Hartmut, Chen, Naijun, Mahinda Karunaratne, P., Kavanaugh, Arthur

Journal:

Year:

2014

Language:

english

File:

PDF, 64 KB

english, 2014

91

88. Efficacy of Adalimumab Plus Methotrexate Therapy in Rheumatoid Arthritis Non-Responders Receiving Methotrexate Monotherapy or Adalimumab Combination Therapy: Results from the Optima Trial

Smolen, Josef S., van Vollenhoven, Ronald F., Fleischmann, Roy, Emery, Paul, Florentinus, Stefan, Rathmann, Suchitrita S., Cardoso, Anabela, Kupper, Hartmut, Kavanaugh, Arthur

Journal:

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

92

074 Summary of indirect comparison to evaluate efficacy of baricitinib with targeted synthetic and biologic disease anti-rheumatic drugs in patients with rheumatoid arthritis

Emery, Paul, Dudler, Jean, Smolen, Josef, Zerbini, Cristiano, Burmester, Gerd, Fautrel, Bruno, van der Laar, Mart, Fleischmann, Roy, Fakhouri, Walid, Leonardis, Francesco De, Zhu, Baojin, Kadziola, Zb

Journal:

Year:

2019

Language:

english

File:

PDF, 74 KB

english, 2019

93

226 Summary of baricitinib effect on patient-reported outcomes (PROs) in methotrexate-inadequate responder patient population

Dougados, Maxime, Fautrel, Bruno J, Van De Laar, Mart A F J, Kirkham, Bruce, Alten, Rieke, Cseuz, Regina, Smolen, Josef S, Sanchez-Burson, Juan, Bird, Paul, Scheinberg, Morton, Van Den Bosch, Filip, B

Journal:

Year:

2018

Language:

english

File:

PDF, 65 KB

english, 2018

94

A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial

Mease, Philip J, Smolen, Josef S, Behrens, Frank, Nash, Peter, Liu Leage, Soyi, Li, Lingnan, Tahir, Hasan, Gooderham, Melinda, Krishnan, Eswar, Liu-Seifert, Hong, Emery, Paul, Pillai, Sreekumar G, Hel

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 917 KB

2020

95

Role of p90 ribosomal S6 kinase in long-term synaptic facilitation and enhanced neuronal excitability

Liu, Rong-Yu, Zhang, Yili, Smolen, Paul, Cleary, Leonard J., Byrne, John H.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.39 MB

2020

96

Testing different thresholds for patient global assessment in defining remission for rheumatoid arthritis: are the current ACR/EULAR Boolean criteria optimal?

Studenic, Paul, Felson, David, de Wit, Maarten, Alasti, Farideh, Stamm, Tanja A, Smolen, Josef S, Aletaha, Daniel

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 909 KB

2020

97

Pooled analysis of TNF inhibitor biosimilar studies comparing radiographic progression by disease activity states in rheumatoid arthritis

Smolen, Josef S, Choe, Jung-Yoon, Weinblatt, Michael E, Emery, Paul, Keystone, Edward, Genovese, Mark C, Myung, Gihyun, Hong, Evelyn, Baek, Inyoung, Ghil, Jeehoon

Journal:

Year:

2020

File:

PDF, 660 KB

2020

98

Response to: âIncreasing the threshold for patient global assessment in defining remission may have a different impact in patients with early and established rheumatoid arthritisâ by Bugatti et al

Studenic, Paul, Felson, David T, de Wit, Maarten, Smolen, Josef S, Aletaha, Daniel

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 237 KB

2020

99

Temporary interruption of baricitinib: characterization of interruptions and effect on clinical outcomes in patients with rheumatoid arthritis

Emery, Paul, Tanaka, Yoshiya, Cardillo, Tracy, Schlichting, Douglas, Rooney, Terence, Beattie, Scott, Helt, Cameron, Smolen, Josef S.

Journal:

Arthritis Research & Therapy

Year:

2020

File:

PDF, 1009 KB

2020

100

Correction to: Temporary interruption of baricitinib: characterization of interruptions and effect on clinical outcomes in patients with rheumatoid arthritis

Emery, Paul, Tanaka, Yoshiya, Cardillo, Tracy, Schlichting, Douglas, Rooney, Terence, Beattie, Scott, Helt, Cameron, Smolen, Josef S.

Journal:

Arthritis Research & Therapy

Year:

2020

File:

PDF, 523 KB

2020