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51

Solution NMR study of environmental effects on substrate seating in human heme oxygenase: Influence of polypeptide truncation, substrate modification and axial ligand

Wenfeng Zhu, Yiming Li, Jinling Wang, Paul R. Ortiz de Montellano, Gerd N. La Mar

Journal:

Journal of Inorganic Biochemistry

Year:

2006

Language:

english

File:

PDF, 400 KB

english, 2006

52

Inhibition of the HIV-1 and HIV-2 proteases by curcumin and curcumin boron complexes

Zhihua Sui, Rafael Salto, Jia Li, Charles Craik, Paul R. Ortiz de Montellano

Journal:

Bioorganic & Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 995 KB

english, 1993

53

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

Hugues Ouellet, Shenheng Guan, Jonathan B. Johnston, Eric D. Chow, Petrea M. Kells, Alma L. Burlingame, Jeffery S. Cox, Larissa M. Podust, Paul R. Ortiz De Montellano

Journal:

Molecular Microbiology

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

54

10.1038/12319

Poulos, Thomas L., Schuller, David J., Wilks, Angela, Ortiz de Montellano, Paul R.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.23 MB

english, 1999

55

Molecular Engineering of Horseradish Peroxidase. Highly Enantioselective Sulfoxidation of Aryl Alkyl Sulfides by the Phe-41 .fwdarw. Leu Mutant

Ortiz de Montellano, Paul R., Ozaki, Shin-Ichi

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 209 KB

english, 1994

56

Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1

Jonathan B. Johnston, Arti A. Singh, Anaelle A. Clary, Chiung-Kuan Chen, Patricia Y. Hayes, Sharon Chow, James J. De Voss, Paul R. Ortiz de Montellano

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 909 KB

english, 2012

57

Computer-Assisted Design of Selective Imidazole Inhibitors for Cytochrome P450 Enzymes

Verras, Andreas, Kuntz, Irwin D., Ortiz de Montellano, Paul R.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

58

EpoK, a Cytochrome P450 Involved in Biosynthesis of the Anticancer Agents Epothilones A and B. Substrate-Mediated Rescue of a P450 Enzyme†

Ogura, Hiroshi, Nishida, Clinton R., Hoch, Ute R., Perera, Roshan, Dawson, John H., Ortiz de Montellano, Paul R.

Journal:

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

59

Self-catalyzed destruction of insect cytochrome P-450

René Feyereisen, Kevin C. Langry, Paul R. Ortiz de Montellano

Journal:

Insect Biochemistry

Year:

1984

Language:

english

File:

PDF, 754 KB

english, 1984

60

Ligation of the iron in the heme-heme oxygenase complex: X-ray absorption, electronic absorption and magnetic circular dichroism studies

Barton K. Hawkins, Angela Wilks, Linda S. Powers, Paul R. Ortiz de Montellano, John H. Dawson

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1996

Language:

english

File:

PDF, 810 KB

english, 1996

61

Transition metals in oxidative stress

Paul R. Ortiz de Montellano, Angela Wilks, Yearn K. Choe, Carlos E. Catalano, Juan C. Alvarez

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 102 KB

english, 1990

62

Bioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases

Clinton R. Nishida, Paul R. Ortiz de Montellano

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

63

Identification of the myoglobin tyrosyl radical by immuno-spin trapping and its dimerization

Charles D. Detweiler, Olivier M. Lardinois, Leesa J. Deterding, Paul R. Ortiz de Montellano, Kenneth B. Tomer, Ronald P. Mason

Journal:

Free Radical Biology and Medicine

Year:

2005

Language:

english

File:

PDF, 308 KB

english, 2005

64

Ligand-Induced Conformational Heterogeneity of Cytochrome P450 CYP119 Identified by 2D NMR Spectroscopy with the Unnatural Amino Acid 13C-p-Methoxyphenylalanine

Lampe, Jed N., Floor, Stephen N., Gross, John D., Nishida, Clinton R., Jiang, Yongying, Trnka, Michael J., Ortiz de Montellano, Paul R.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 128 KB

english, 2008

65

Synthesis of Photoaffinity Probes for Heme-Containing Proteins

Tschirret-Guth, Richard A., Ortiz de Montellano, Paul R.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 113 KB

english, 1998

66

Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis

He, Xin, Alian, Akram, Stroud, Robert, Ortiz de Montellano, Paul R.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 555 KB

english, 2006

67

Oxidation of ω-Oxo Fatty Acids by Cytochrome P450BM-3(CYP102)

S.Christopher Davis, Zhihua Sui, Julian A. Peterson, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 187 KB

english, 1996

68

Active-Site Topologies of Human CYP2D6 and Its Aspartate-301 → Glutamate, Asparagine, and Glycine Mutants

Richard Mackman, Richard A. Tschirret-Guth, Gillian Smith, Graham P. Hayhurst, S.Wynne Ellis, Martin S. Lennard, Geoffrey T. Tucker, C.Roland Wolf, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 316 KB

english, 1996

69

Protein Radicals in Myoglobin Dimerization and Myoglobin-Catalyzed Styrene Epoxidation

Richard A. Tschirret-Guth, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 178 KB

english, 1996

70

Human Endothelial Nitric Oxide Synthase: Expression inEscherichia coli,Coexpression with Calmodulin, and Characterization

Ignacio Rodrı&amp, #x0301, guez-Crespo, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 135 KB

english, 1996

71

Characterization of Human Liver Inducible Nitric Oxide Synthase Expressed inEscherichia coli

Nancy Counts Gerber, Clinton R. Nishida, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

72

Horseradish Peroxidase: Partial Rescue of the His-42 → Ala Mutant by a Concurrent Asn-70 → Asp Mutation

Marina I. Savenkova, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 165 KB

english, 1998

73

Cytochrome P450camSubstrate Specificity: Relationship between Structure and Catalytic Oxidation of Alkylbenzenes

Ole Sibbesen, Zhoupeng Zhang, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 255 KB

english, 1998

74

Binding of Dynein Light Chain (PIN) to Neuronal Nitric Oxide Synthase in the Absence of Inhibition

Ignacio Rodrı&amp, #x0301, guez-Crespo, Wesley Straub, Francisco Gavilanes, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 160 KB

english, 1998

75

Reduction of Peroxides and Dinitrobenzenes byMycobacterium tuberculosisThioredoxin and Thioredoxin Reductase

Zhoupeng Zhang, Patrick J. Hillas, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 101 KB

english, 1999

76

Structural Determination of the Substrate Specificities and Regioselectivities of the Rat and Human Fatty Acid ω-Hydroxylases

Ute Hoch, Zhoupeng Zhang, Deanna L. Kroetz, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

77

EPR Spin-Trapping of a Myeloperoxidase Protein Radical

Olivier M. Lardinois, Paul R. Ortiz de Montellano

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 59 KB

english, 2000

78

Destruction of cytochrome P-450 by 2-isopropyl-4-pentenamide and methyl 2-isopropyl-4-pentenoate: Mass spectrometric characterization of prosthetic heme adducts and nonparticipation of epoxide metabolites

Paul R.Ortiz De Montellano, Garold S. Yost, Bruce A. Mico, Stephen E. Dinizo, M.Almira Correia, Hidaeki Kumbara

Journal:

Archives of Biochemistry and Biophysics

Year:

1979

Language:

english

File:

PDF, 979 KB

english, 1979

79

Destruction of cytochrome P-450 by allylisopropylacetamide is a suicidal process

Paul R.Ortiz De Montellano, Bruce A. Mico

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 765 KB

english, 1981

80

Selective inactivation of cytochrome P-450 isozymes by suicide substrates

Paul R.Ortiz De Montellano, Bruce A. Mico, James M. Mathews, Kent L. Kunze, Gerald T. Miwa, Anthony Y.H. Lu

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.05 MB

english, 1981

81

Shift of the acetylenic hydrogen during chemical and enzymatic oxidation of the biphenylacetylene triple bond

Paul R.Ortiz De Montellano, Kent L. Kunze

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 246 KB

english, 1981

82

Autocatalytic inactivation of plant cytochrome P-450 enzymes: Selective inactivation of cinnamic acid 4-hydroxylase from Helianthus tuberosus by 1-aminobenzotriazole

Daniele Reichhart, Annick Simon, Francis Durst, James M. Mathews, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 708 KB

english, 1982

83

Autocatalytic inactivation of plant cytochrome P-450 enzymes: Selective inactivation of the lauric acid in-chain hydroxylase from Helianthus tuberosus L. by unsaturated substrate analogs

Jean-Pierre Salaun, Daniele Reichhart, Annick Simon, Francis Durst, Norbert O. Reich, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 620 KB

english, 1984

84

Dissociation of cytochrome P-450 inactivation and induction

Paul R. Ortiz de Montellano, Anita K. Costa

Journal:

Archives of Biochemistry and Biophysics

Year:

1986

Language:

english

File:

PDF, 936 KB

english, 1986

85

Differential inactivation of plant lauric acid ω- and in-chain-hydroxylases by terminally unsaturated fatty acids

Jean-Pierre Salaün, Annick Simon, Francis Durst, Norbert O. Reich, Paul R.Ortiz De Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 538 KB

english, 1988

86

Inactivation of lignin peroxidase by phenylhydrazine and sodium azide

Gia D. DePillis, Hiroyuki Wariishi, Michael H. Gold, Paul R.Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1990

Language:

english

File:

PDF, 819 KB

english, 1990

87

Topological analysis of the active sites of cytochromes P450IIB4 (rabbit), P450IIB10 (mouse), and P450IIB11 (dog) by in situ rearrangement of phenyl-iron complexes

Barbara A. Swanson, James R. Halpert, Lester M. Bornheim, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 558 KB

english, 1992

88

Cytochrome P450cam-catalyzed oxidation of a hypersensitive radical probe

Vaughn P. Miller, Julia A. Fruetel, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 748 KB

english, 1992

89

Baculovirus expression and characterization of catalytically active horseradish peroxidase

Christa Hartmann, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 2.24 MB

english, 1992

90

Inactivation of hepatic cytochrome p-450 by a 1,2,3-benzothiadiazole insecticide synergist

Paul R.Ortiz De Montellano, James M. Mathews

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 411 KB

english, 1981

91

Dissociation of increased lauric acid ω-hydroxylase activity from the antilipidemic action of clofibrate

Norbert O. Reich, Paul R.Ortiz De Montellano

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 774 KB

english, 1986

92

Effects of 3-(2-phenylethyl)-4-methylsydnone and related sydnones on heme biosynthesis

Jane E. Mackie, Paul R.Ortiz de Montellano, Lawrence A. Grab, Gerald S. Marks

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 820 KB

english, 1990

93

The Sulfolobus solfataricus electron donor partners of thermophilic CYP119: an unusual non-NAD(P)H-dependent cytochrome P450 system

Andrei V. Puchkaev, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 535 KB

english, 2005

94

Heme-protein covalent bonds in peroxidases and resistance to heme modification during halide oxidation

Liusheng Huang, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2006

Language:

english

File:

PDF, 413 KB

english, 2006

95

Functional expression and characterization of cytochrome P450 52A21 from Candida albicans

Donghak Kim, Max J. Cryle, James J. De Voss, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 1.27 MB

english, 2007

96

Efficient catalytic turnover of cytochrome P450cam is supported by a T252N mutation

Donghak Kim, Yong-Seok Heo, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

97

The Mycobacterium tuberculosis cytochrome P450 system

Hugues Ouellet, Jonathan B. Johnston, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2010

Language:

english

File:

PDF, 737 KB

english, 2010

98

Structural control of cytochrome P450-catalyzed ω-hydroxylation

Jonathan B. Johnston, Hugues Ouellet, Larissa M. Podust, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

99

Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans

Hyoung-Goo Park, Im-Soon Lee, Young-Jin Chun, Chul-Ho Yun, Jonathan B. Johnston, Paul R. Ortiz de Montellano, Donghak Kim

Journal:

Archives of Biochemistry and Biophysics

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

100

Active-site residues move independently from the rest of the protein in a 200 ns molecular dynamics simulation of cytochrome P450 CYP119

Relly Brandman, Jed N. Lampe, Yigal Brandman, Paul R. Ortiz de Montellano

Journal:

Archives of Biochemistry and Biophysics

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011