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51

Characterization of Abnormal Wall Shear Stress Using 4D Flow MRI in Human Bicuspid Aortopathy

van Ooij, Pim, Potters, Wouter V., Collins, Jeremy, Carr, Maria, Carr, James, Malaisrie, S. Chris, Fedak, Paul W. M., McCarthy, Patrick M., Markl, Michael, Barker, Alex J.

Journal:

Annals of Biomedical Engineering

Year:

2015

Language:

english

File:

PDF, 3.74 MB

english, 2015

52

Bicuspid aortopathy and the development of individualized resection strategies

Fedak, Paul W.M., Verma, Subodh

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

53

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2

Ngu, Janet M.C., Teng, Guoqi, Meijndert, Hans Christopher, Mewhort, Holly E., Turnbull, Jeannine D., Stetler-Stevenson, William G., Fedak, Paul W.M.

Journal:

Cardiovascular Pathology

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

54

Cardiac Regeneration with Embryonic Stem Cells: Historic Recapitulation of Heart Transplantation

Fedak, Paul W.M.

Journal:

Stem Cells and Development

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

55

Health technology assessments and innovation

Tucker, Joseph, Boone, Katherine, Fedak, Paul

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 657 KB

english, 2013

56

[IEEE 2010 9th International Symposium on Parallel and Distributed Computing (ISPDC) - Istanbul, Turkey (2010.07.7-2010.07.9)] 2010 Ninth International Symposium on Parallel and Distributed Computing - DSL-Lab: A Low-Power Lightweight Platform to Experiment on Domestic Broadband Internet

Fedak, Gilles, Gelas, Jean-Patrick, Herault, Thomas, Iniesta, Victor, Kondo, Derrick, Lefevre, Laurent, Malécot, Paul, Nussbaum, Lucas, Rezmerita, Ala, Richard, Olivier

Year:

2010

Language:

english

File:

PDF, 491 KB

english, 2010

57

Bicuspid aortic valve disease: recent insights in pathophysiology and treatment

Fedak, Paul WM, David, Tirone E, Borger, Michael, Verma, Subodh, Butany, Jagdish, Weisel, Richard D

Journal:

Expert Review of Cardiovascular Therapy

Year:

2005

Language:

english

File:

PDF, 790 KB

english, 2005

58

Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome

Bracey, Nathan A., Gershkovich, Benjamin, Chun, Justin, Vilaysane, Akosua, Meijndert, H. Christopher, Wright, James R., Fedak, Paul W., Beck, Paul L., Muruve, Daniel A., Duff, Henry J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.81 MB

english, 2014

59

Comparison of Outcomes and Presentation in Men-Versus-Women With Bicuspid Aortic Valves Undergoing Aortic Valve Replacement

Andrei, Adin-Cristian, Yadlapati, Ajay, Malaisrie, S. Chris, Puthumana, Jyothy J., Li, Zhi, Rigolin, Vera H., Mendelson, Marla, Clennon, Colleen, Kruse, Jane, Fedak, Paul W.M., Thomas, James D., Higgi

Journal:

The American Journal of Cardiology

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

60

Na+ current expression in human atrial myofibroblasts: identity and functional roles

KoivumÃ¤ki, Jussi T., Clark, Robert B., Belke, Darrell, Kondo, Colleen, Fedak, Paul W. M., Maleckar, Mary M. C., Giles, Wayne R.

Journal:

Frontiers in Physiology

Year:

2014

Language:

english

File:

PDF, 4.12 MB

english, 2014

61

Tetrandrine reverses human cardiac myofibroblast activation and myocardial fibrosis

Teng, Guoqi, Svystonyuk, Daniyil, Mewhort, Holly E. M., Turnbull, Jeannine D., Belke, Darrell D., Duff, Henry J., Fedak, Paul W. M.

Journal:

AJP Heart and Circulatory Physiology

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

62

Tissue-Engineered Grafts Matured in the Right Ventricular Outflow Tract

Ozawa, Tsukasa, Mickle, Donald A. G., Weisel, Richard D., Matsubayashi, Keiji, Fujii, Takeshiro, Fedak, Paul W. M., Koyama, Nobuya, Ikada, Yoshito, Li, Ren-Ke

Journal:

Cell Transplantation

Year:

2004

File:

PDF, 1.41 MB

2004

63

Tissue-Engineered Grafts Matured in the Right Ventricular Outflow Tract

Ozawa, Tsukasa, Mickle, Donald A. G., Weisel, Richard D., Matsubayashi, Keiji, Fujii, Takeshiro, Fedak, Paul W. M., Koyama, Nobuya, Ikada, Yoshito, Li, Ren-Ke

Journal:

Cell Transplantation

Year:

2004

Language:

english

File:

PDF, 1.41 MB

english, 2004

64

Improvement of endothelial function in insulin-resistant carotid arteries treated with pravastatin

Dumont, Aaron S., Hyndman, M. Eric, Dumont, Randall J., Fedak, Paul M., Kassell, Neal F., Sutherland, Garnette R., Verma, Subodh

Journal:

Journal of Neurosurgery

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

65

Real estate of the bicuspid aorta: location, location, location!

Fedak, Paul W.M., Guzzardi, David G.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2016

Language:

english

File:

PDF, 330 KB

english, 2016

66

Differential impact of mechanical unloading on structural and nonstructural components of the extracellular matrix in advanced human heart failure

Sakamuri, Siva S.V.P., Takawale, Abhijit, Basu, Ratnadeep, Fedak, Paul W.M., Freed, Darren, Sergi, Consolato, Oudit, Gavin Y., Kassiri, Zamaneh

Journal:

Translational Research

Year:

2016

Language:

english

File:

PDF, 5.34 MB

english, 2016

67

Year in review

Fedak, Paul W.M., Barker, Alex J., Verma, Subodh

Journal:

Current Opinion in Cardiology

Year:

2016

Language:

english

File:

PDF, 7.55 MB

english, 2016

68

Is Concomitant Aortopathy Unique With Bicuspid Aortic Valve Stenosis?∗

Fedak, Paul W.M., Barker, Alex J.

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 127 KB

english, 2016

69

Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-β 1

Mewhort, Holly E. M., Lipon, Brodie D., Svystonyuk, Daniyil A., Teng, Guoqi, Guzzardi, David G., Silva, Claudia, Yong, V. Wee, Fedak, Paul W. M.

Journal:

AJP Heart and Circulatory Physiology

Year:

2016

Language:

english

File:

PDF, 2.58 MB

english, 2016

70

Reply

Guzzardi, David G., Barker, Alex J., Markl, Michael, Fedak, Paul W.M.

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 128 KB

english, 2016

71

Reply

Barker, Alex J., Guzzardi, David, Markl, Michael, Fedak, Paul W.M.

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 431 KB

english, 2016

72

Epicardial infarct repair with bioinductive extracellular matrix promotes vasculogenesis and myocardial recovery

Mewhort, Holly E.M., Turnbull, Jeannine D., Satriano, Alessandro, Chow, Kelvin, Flewitt, Jacqueline A., Andrei, Adin-Cristian, Guzzardi, David G., Svystonyuk, Daniyil A., White, James A., Fedak, Paul

Journal:

The Journal of Heart and Lung Transplantation

Year:

2016

Language:

english

File:

PDF, 5.05 MB

english, 2016

73

Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling

Svystonyuk, Daniyil A, Ngu, Janet MC, Mewhort, Holly EM, Lipon, Brodie D, Teng, Guoqi, Guzzardi, David G, Malik, Getanshu, Belke, Darrell D, Fedak, Paul WM

Journal:

Journal of Translational Medicine

Year:

2015

Language:

english

File:

PDF, 3.53 MB

english, 2015

74

Does Ischemic Preconditioning Afford Clinically Relevant Cardioprotection?

Mikhail, Peter, Verma, Subodh, Fedak, Paul W.M., Weisel, Richard D., Li, Ren-Ke

Journal:

American Journal of Cardiovascular Drugs

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

75

The Role of Plasma from Platelet Concentrates in Transfusion Reactions

HEDDLE, NANCY M., KLAMA, LUBA, SINGER, JOEL, RICHARDS, CARL, FEDAK, PAUL, WALKER, IRWIN, KELTON, JOHN G.

Journal:

Survey of Anesthesiology

Year:

1995

File:

PDF, 78 KB

1995

76

Statin Use and Aneurysm Risk in Patients With Bicuspid Aortic Valve Disease

Taylor, Alexander P., Yadlapati, Ajay, Andrei, Adin-Cristian, Li, Zhi, Clennon, Colleen, McCarthy, Patrick M., Thomas, James D., Malaisrie, S. Chris, Stone, Neil J., Bonow, Robert O., Fedak, Paul W.M.

Journal:

Clinical Cardiology

Year:

2016

Language:

english

File:

PDF, 342 KB

english, 2016

77

Cardioprotective c-kit + cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines

Fazel, Shafie, Cimini, Massimo, Chen, Liwen, Li, Shuhong, Angoulvant, Denis, Fedak, Paul, Verma, Subodh, Weisel, Richard D, Keating, Armand, Li, Ren-ke

Year:

2006

Language:

english

File:

PDF, 1.93 MB

english, 2006

78

Development and Validation of –Expressed Molecular Markers Specific for the Long Arm of Chromosome 7E

Gou, Lulu, Hattori, Jiro, Fedak, George, Balcerzak, Margaret, Sharpe, Andrew, Visendi, Paul, Edwards, David, Tinker, Nicholas, Wei, Yu-Ming, Chen, Guo-Yue, Ouellet, Thérèse

Journal:

Year:

2016

Language:

english

File:

PDF, 5.89 MB

english, 2016

79

Bicuspid aortic valve and the specialty clinic: are your patients at risk?

Fedak, Paul W. M.

Journal:

Cardiology in the Young

Year:

2017

Language:

english

File:

PDF, 61 KB

english, 2017

80

Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold

Park, Daniel, Mewhort, Holly, Teng, Guoqi, Belke, Darrell, Turnbull, Jeannine, Svystonyuk, Daniyil, Guzzardi, David, Kang, Sean, Fedak, Paul W.M.

Journal:

Tissue Engineering Part A

Year:

2017

Language:

english

File:

PDF, 466 KB

english, 2017

81

Bicuspid aortic valve aortopathy

Guzzardi, David G., Verma, Subodh, Fedak, Paul W.M.

Journal:

Current Opinion in Cardiology

Year:

2016

Language:

english

File:

PDF, 486 KB

english, 2016

82

The Cost of Frailty in Cardiac Surgery

Yanagawa, Bobby, Latter, David, Fedak, Paul W.M., Cutrara, Charles, Verma, Subodh

Journal:

Canadian Journal of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

83

Catalyzing capital for Canada's life sciences industry

Joseph Tucker,Justin Chakma,Paul WM Fedak…

Journal:

Journal of Commercial Biotechnology

Year:

2011

Language:

english

File:

PDF, 322 KB

english, 2011

84

l-Arginine protects human heart cells from low-volume anoxia and reoxygenation

Shiono, Noritsugu, Rao, Vivek, Weisel, Richard D., Kawasaki, Muneyasu, Li, Ren-Ke, Mickle, Donald A. G., Fedak, Paul W. M., Tumiati, Laura C., Ko, Lawrence, Verma, Subodh

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2002

Language:

english

File:

PDF, 427 KB

english, 2002

85

Mind the Gap: Current challenges and future state of heart failure care

McDonald, Michael A., Ashley, Euan A., Fedak, Paul WM., Hawkins, Nathaniel, Januzzi, James L., McMurray, John JV., Parikh, Victoria N., Rao, Vivek, Svystonyuk, Daniyil, Teerlink, John R., Virani, Sean

Journal:

Canadian Journal of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

86

Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4‐Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects

van Ooij, Pim, Markl, Michael, Collins, Jeremy D., Carr, James C., Rigsby, Cynthia, Bonow, Robert O., Malaisrie, S. Chris, McCarthy, Patrick M., Fedak, Paul W.M., Barker, Alex J.

Journal:

Journal of the American Heart Association

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

87

Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3

Fedak, Paul W. M., Altamentova, Svetlana M., Weisel, Richard D., Nili, Nafiseh, Ohno, Nobuhisa, Verma, Subodh, Lee, Tsu-Yee J., Kiani, Chris, Mickle, Donald A. G., Strauss, Bradley H., Li, Ren-Ke

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2003

Language:

english

File:

PDF, 576 KB

english, 2003

88

Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair

Mewhort, Holly E.M., Svystonyuk, Daniyil A., Turnbull, Jeannine D., Teng, Guoqi, Belke, Darrell D., Guzzardi, David G., Park, Daniel S., Kang, Sean, Hollenberg, Morley D., Fedak, Paul W.M.

Journal:

JACC: Basic to Translational Science

Year:

2017

Language:

english

File:

PDF, 2.89 MB

english, 2017

89

Bicuspid aortic valve-associated aortopathy

Maredia, Ashna K., Greenway, Steven C., Verma, Subodh, Fedak, Paul W.M.

Journal:

Current Opinion in Cardiology

Year:

2017

Language:

english

File:

PDF, 231 KB

english, 2017

90

Perioperative evaluation of regional aortic wall shear stress patterns in patients undergoing aortic valve and/or proximal thoracic aortic replacement

Bollache, Emilie, Fedak, Paul W.M., van Ooij, Pim, Rahman, Ozair, Malaisrie, S. Chris, McCarthy, Patrick M., Carr, James C., Powell, Alex, Collins, Jeremy D., Markl, Michael, Barker, Alex J.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

91

Seeing a tree through the forest: Precision medicine tools can enhance donor allocation in heart transplantation

Vasanthan, Vishnu, Fedak, Paul W.M.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2017

Language:

english

File:

PDF, 174 KB

english, 2017

92

Safety and efficacy of prophylactic negative pressure wound therapy following open saphenous vein harvest in cardiac surgery: a feasibility study

Lee, Arthur J., Sheppard, Christina E., Kent, William D.T., Mewhort, Holly, Sikdar, Khokan C., Fedak, Paul W.M.

Journal:

Interactive Cardiovascular and Thoracic Surgery

Year:

2016

Language:

english

File:

PDF, 192 KB

english, 2016

93

Aortic Valve Replacement in an Era of Rapid Innovation

Fedak, Paul W.M., Bhatt, Deepak L., Verma, Subodh

Journal:

Journal of the American College of Cardiology

Year:

2018

Language:

english

File:

PDF, 689 KB

english, 2018

94

Human pericardial proteoglycan 4 (lubricin): Implications for postcardiotomy intrathoracic adhesion formation

Park, Daniel S.J., Regmi, Suresh C., Svystonyuk, Daniyil A., Teng, Guoqi, Belke, Darrell, Turnbull, Jeannine, Guzzardi, David G., Kang, Sean, Cowman, Mary K., Schmidt, Tannin A., Fedak, Paul W.M.

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2018

Language:

english

File:

PDF, 3.82 MB

english, 2018

95

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

El-Daly, Mahmoud, Venu, Vivek Krishna Pulakazhi, Saifeddine, Mahmoud, Mihara, Koichiro, Kang, Sean, Fedak, Paul W.M., Alston, Laurie A., Hirota, Simon A., Ding, Hong, Triggle, Chris R., Hollenberg, Mo

Journal:

Vascular Pharmacology

Year:

2018

Language:

english

File:

PDF, 4.61 MB

english, 2018

96

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm

Shen, Mengcheng, Hu, Mei, Fedak, Paul W, Oudit, Gavin Y, Kassiri, Zamaneh

Journal:

Circulation Research

Year:

2018

Language:

english

File:

PDF, 5.10 MB

english, 2018

97

Hyperglycaemic Impairment of PAR2-Mediated Vasodilatation: Prevention by Inhibition of SGLT2 and Minimizing Mitochondrial Dysfunction

Pulakazhi Venu, Vivek K., El-Daly, Mahmoud, Mahmoud, Saifeddine, Mihara, Koichiro, Fedak, Paul W., Triggle, Christopher R., Hirota, Simon A., Hollenberg, Morley D.

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 45 KB

english, 2018

98

The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve–related aortopathy: Executive summary

Borger, Michael A., Fedak, Paul W.M., Stephens, Elizabeth H., Gleason, Thomas G., Girdauskas, Evaldas, Ikonomidis, John S., Khoynezhad, Ali, Siu, Samuel C., Verma, Subodh, Hope, Michael D., Cameron, D

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2018

Language:

english

File:

PDF, 302 KB

english, 2018

99

The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve–related aortopathy: Full online-only version

Borger, Michael A., Fedak, Paul W.M., Stephens, Elizabeth H., Gleason, Thomas G., Girdauskas, Evaldas, Ikonomidis, John S., Khoynezhad, Ali, Siu, Samuel C., Verma, Subodh, Hope, Michael D., Cameron, D

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2018

Language:

english

File:

PDF, 4.13 MB

english, 2018

100

Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair

Svystonyuk, Daniyil A., Mewhort, Holly E. M., Fedak, Paul W. M.

Journal:

Frontiers in Cardiovascular Medicine

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018