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1

Differential effects of progressive familial intrahepatic cholestasis type 1 and benign recurrent intrahepatic cholestasis type 1 mutations on canalicular localization of ATP8B1

Dineke E. Folmer, Vincent A. van der Mark, Kam S. Ho-Mok, Ronald P.J. Oude Elferink, Coen C. Paulusma

Journal:

Year:

2009

Language:

english

File:

PDF, 3.46 MB

english, 2009

2

Multidrug resistance associated protein 2 mediates transport of prostaglandin E2

Dirk R. De Waart, Coen C. Paulusma, Cindy Kunne, Ronald P. J. Oude Elferink

Journal:

Liver International

Year:

2006

Language:

english

File:

PDF, 172 KB

english, 2006

3

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

Coen C. Paulusma, Annemiek Groen, Cindy Kunne, Kam S. Ho-Mok, Astrid L. Spijkerboer, D. Rudi de Waart, Frans J. Hoek, Heleen Vreeling, Kees A. Hoeben, Jan van Marle, Ludmila Pawlikowska, Laura N. Bull

Journal:

Year:

2006

Language:

english

File:

PDF, 897 KB

english, 2006

4

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity

Coen C. Paulusma, Dineke E. Folmer, Kam S. Ho-Mok, D. Rudi de Waart, Petra M. Hilarius, Arthur J. Verhoeven, Ronald P. J. Oude Elferink

Journal:

Year:

2008

Language:

english

File:

PDF, 1.41 MB

english, 2008

5

A biliary HCO3− umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes

Simon Hohenester, Lucas Maillette de Buy Wenniger, Coen C. Paulusma, Sandra J. van Vliet, Douglas M. Jefferson, Ronald P. Oude Elferink, Ulrich Beuers

Journal:

Year:

2012

Language:

english

File:

PDF, 954 KB

english, 2012

6

Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver

Coen C. Paulusma, M. J. Kothe, Conny T. Bakker, Piter J. Bosma, Irene van Bokhoven, Jan van Marle, Ulrich Bolder, Guido N. Tytgat, Ronald P. Elferink

Journal:

Year:

2000

Language:

english

File:

PDF, 829 KB

english, 2000

7

Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)

Ronald P. J. Oude Elferink, Coen C. Paulusma

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 332 KB

english, 2007

8

The flip side of cardiolipin import

Paulusma, Coen C, Houwen, Roderick H J, Williamson, Patrick L

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

9

P4 ATPases – The physiological relevance of lipid flipping transporters

Coen C. Paulusma, Ronald P.J. Oude Elferink

Journal:

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

10

Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52

Lieneke R. van Veelen, Jeroen Essers, Mandy W.M.M. van de Rakt, Hanny Odijk, Albert Pastink, Małgorzata Z. Zdzienicka, Coen C. Paulusma, Roland Kanaar

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 544 KB

english, 2005

11

P4 ATPases - Lipid flippases and their role in disease

Dineke E. Folmer, Ronald P.J. Oude Elferink, Coen C. Paulusma

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 505 KB

english, 2009

12

Diseases of intramembranous lipid transport

Coen C. Paulusma, Ronald P.J. Oude Elferink

Journal:

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

13

Intestinal bile salt absorption in Atp8b1 deficient mice

Annemiek Groen, Cindy Kunne, Coen C. Paulusma, Werner Kramer, Luis B. Agellon, Laura N. Bull, Ronald P.J. Oude Elferink

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 295 KB

english, 2007

14

Linking architecture to infrastructure

Coen C. Paulusma

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 47 KB

english, 2003

15

Hepatocanalicular Transport Defects: Pathophysiologic Mechanisms of Rare Diseases

Ronald P.J. Oude Elferink, Coen C. Paulusma, Albert K. Groen

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 516 KB

english, 2006

16

Abcg5/8 Independent Biliary Cholesterol Excretion in Atp8b1-Deficient Mice

Annemiek Groen, Cindy Kunne, Geartsje Jongsma, Karin van den Oever, Kam S. Mok, Michele Petruzzelli, Carlos L.J. Vrins, Laura Bull, Coen C. Paulusma, Ronald P.J. Oude Elferink

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 980 KB

english, 2008

17

Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity

Niek P van Til, Kirstin M Heutinck, Roos van der Rijt, Coen C Paulusma, Michel van Wijland, David M Markusic, PJ Oude Ronald Elferink, Jurgen Seppen

Journal:

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

18

Complementary Functions of the Flippase ATP8B1 and the Floppase ABCB4 in Maintaining Canalicular Membrane Integrity

Groen, Annemiek, Romero, Marta Rodriguez, Kunne, Cindy, Hoosdally, Sarah J., Dixon, Peter H., Wooding, Carol, Williamson, Catherine, Seppen, Jurgen, van den Oever, Karin, Mok, Kam S., Paulusma, Coen C

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 4.83 MB

english, 2011

19

Mo1038 Obstructive Cholestasis in Rats With Simple Steatosis Is Characterized by Exacerbated Liver Injury and Increased Plasma Bile Salts and Bilirubin

Lionarons, Daniel A., Heger, Michal, Kloek, Jaap J., de Waart, Dirk R., Marsman, Hendrik A., Verheij, Joanne, Beuers, Ulrich, Paulusma, Coen C., Van Gulik, Thomas M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

20

FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model

Kunne, Cindy, Acco, Alexandra, Duijst, Suzanne, de Waart, Dirk R., Paulusma, Coen C., Gaemers, Ingrid, Oude Elferink, Ronald P.J.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 951 KB

english, 2014

21

The lipid flippase heterodimer ATP8B1–CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells

van der Mark, Vincent A., de Waart, D. Rudi, Ho-Mok, Kam S., Tabbers, Merit M., Voogt, Heleen W., Oude Elferink, Ronald P.J., Knisely, A.S., Paulusma, Coen C.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

22

Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis

Kunne, Cindy, de Graaff, Marijke, Duijst, Suzanne, de Waart, Dirk R, Oude Elferink, Ronald P J, Paulusma, Coen C

Journal:

Laboratory Investigation

Year:

2014

Language:

english

File:

PDF, 473 KB

english, 2014

23

Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: Conjugated hypercholanemia without a clear clinical phenotype

Vaz, Frédéric M., Paulusma, Coen C., Huidekoper, Hidde, de Ru, Minke, Lim, Cynthia, Koster, Janet, Ho-Mok, Kam, Bootsma, Albert H., Groen, Albert K., Schaap, Frank G., Oude Elferink, Ronald P. J., Wat

Journal:

Year:

2015

Language:

english

File:

PDF, 623 KB

english, 2015

24

ATP8B1 and ATP11C: Two Lipid Flippases Important for Hepatocyte Function

Naik, Jyoti, de Waart, Dirk R., Utsunomiya, Karina, Duijst, Suzanne, Mok, Kam Ho, Oude Elferink, Ronald P.J., Bosma, Piter J., Paulusma, Coen C.

Journal:

Digestive Diseases

Year:

2015

Language:

english

File:

PDF, 131 KB

english, 2015

25

P4 ATPases: Flippases in Health and Disease

van der Mark, Vincent, Elferink, Ronald, Paulusma, Coen

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 1.43 MB

english, 2013

26

Progressive Familial Intrahepatic Cholestasis Type 1

Paulusma, Coen, Elferink, Ronald, Jansen, Peter

Journal:

Seminars in Liver Disease

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

27

Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells

Ansari, Israr-ul H., Longacre, Melissa J., Paulusma, Coen C., Stoker, Scott W., Kendrick, Mindy A., MacDonald, Michael J.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

28

Defective plasma membrane targeting of p.I661T-ATP8B1, associated with familial intrahepatic cholestasis, can be rescued in vitro by CFTR correctors

van der Woerd, Wendy L., Wichers, Catharina G.K., Vestergaard, Anna L., Andersen, Jens Peter., Paulusma, Coen C., Houwen, Roderick H.J., van de Graaf, Stan F.J.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 5.14 MB

english, 2016

29

Mo2050 Lipid Raft Modulation in Rat Visceral Hypersensitivity: Proof of Principal Study

Botschuijver, Sara, van Diest, Sophie, Strik, Anne, Yu, Zhumei, Welting, Olaf, Boeckxstaens, Guy E., Jennings, Gary, Paulusma, Coen C., Elferink, Ronald Oude, de Jonge, Wouter, van den Wijngaard, Rene

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 272 KB

english, 2015

30

Soluble adenylyl cyclase regulates bile salt-induced apoptosis in human cholangiocytes

Chang, Jung-Chin, Go, Simei, de Waart, Dirk R., Munoz-Garrido, Patricia, Beuers, Ulrich, Paulusma, Coen C., Oude Elferink, Ronald

Journal:

Year:

2016

Language:

english

File:

PDF, 739 KB

english, 2016

31

ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

de Waart, Dirk R., Naik, Jyoti, Utsunomiya, Karina S., Duijst, Suzanne, Ho-Mok, Kam, Bolier, A. Ruth, Hiralall, Johan, Bull, Laura N., Bosma, Piter J., Oude Elferink, Ronald P.J., Paulusma, Coen C.

Journal:

Year:

2016

Language:

english

File:

PDF, 896 KB

english, 2016

32

Multiple black hepatocellular adenomas in a male patient

Bernard, Pierre-Henri, Blanc, Jean F., Paulusma, Coen, Bail, Brigitte Le, Carles, Jacques, Balabaud, Charles, Bioulac-Sage, Paulette

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2000

File:

PDF, 2.32 MB

2000

33

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

PAULUSMA, Coen C., GEER, Michael A. van, EVERS, Raymond, HEIJN, Marc, OTTENHOFF, Roelof, BORST, Piet, OUDE ELFERINK, Ronald P.J.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

34

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

PAULUSMA, Coen C., GEER, Michael A. van, EVERS, Raymond, HEIJN, Marc, OTTENHOFF, Roelof, BORST, Piet, OUDE ELFERINK, Ronald P. J.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

35

Roles of recombination in DNA damage repair

Essers, Jeroen, Tan, T. L. Raoul, Dronkert, Mies L. G., Citterio, Elisabetta, Paulusma, Coen, Ristic, Dejan, Wyman, Claire, Beerens, Cecile, de Wit, Jan, Hoeijmakers, Jan H. J., Kanaar, Roland

Journal:

Biochemical Society Transactions

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

36

Role of Glutathione in the Export of Compounds from Cells by the Multidrug-Resistance-Associated Protein

Guido J. R. Zaman, Jan Lankelma, Olaf van Tellingen, Jos Beijnen, Henk Dekker, Coen Paulusma, Ronald P. J. Oude Elferink, Frank Baas and Piet Borst

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

37

The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator

van der Mark, Vincent A., de Jonge, Hugo R., Chang, Jung-Chin, Ho-Mok, Kam S., Duijst, Suzanne, Vidović, Dragana, Carlon, Marianne S., Oude Elferink, Ronald P.J., Paulusma, Coen C.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2016

Language:

english

File:

PDF, 901 KB

english, 2016

38

Extended Abstract: Deficiency of Sodium Taurocholate Cotransporting Polypeptide (SLC10A1): A New Inborn Error of Metabolism with an Attenuated Phenotype

Vaz, Frédéric M., Huidekoper, Hidde H., Paulusma, Coen C.

Journal:

Digestive Diseases

Year:

2017

Language:

english

File:

PDF, 112 KB

english, 2017

39

The P4-ATPase ATP9A is a novel determinant of exosome release

Naik, Jyoti, Hau, Chi M., ten Bloemendaal, Lysbeth, Mok, Kam S., Hajji, Najat, Wehman, Ann M., Meisner, Sander, Muncan, Vanesa, Paauw, Nanne J., de Vries, H. E., Nieuwland, Rienk, Paulusma, Coen C., B

Journal:

Year:

2019

File:

PDF, 2.30 MB

2019

40

Liver-directed gene therapy results in long term correction of progressive familial intrahepatic cholestasis type 3 in mice

Aronson, Sem J., Bakker, Robert S., Shi, Xiaoxia, Duijst, Suzanne, ten Bloemendaal, Lysbeth, de Waart, Dirk R., Verheij, Joanne, Elferink, Ronald P. Oude, Beuers, Ulrich, Paulusma, Coen C., Bosma, Pit

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 2.26 MB

english, 2019

41

The P4-ATPase ATP9A is a novel determinant of exosome release

Naik, Jyoti, Hau, Chi M., ten Bloemendaal, Lysbeth, Mok, Kam S., Hajji, Najat, Wehman, Ann M., Meisner, Sander, Muncan, Vanesa, Paauw, Nanne J., de Vries, H. E., Nieuwland, Rienk, Paulusma, Coen C., B

Journal:

Year:

2019

Language:

english

File:

PDF, 2.30 MB

english, 2019

42

Blocking sodium‐taurocholate cotransporting polypeptide stimulates biliary cholesterol and phospholipid secretion

Roscam Abbing, Reinout L.P., Slijepcevic, Davor, Donkers, Joanne M., Havinga, Rick, Duijst, Suzanne, Paulusma, Coen C, Kuiper, Johan, Kuipers, Folkert, Groen, Albert K., Oude Elferink, Ronald P.J., va

Journal:

Year:

2019

Language:

english

File:

PDF, 912 KB

english, 2019

43

Farnesoid X receptor and bile acids regulate vitamin A storage

Saeed, Ali, Yang, Jing, Heegsma, Janette, Groen, Albert K., van Mil, Saskia W. C., Paulusma, Coen C., Zhou, Lu, Wang, Bangmao, Faber, Klaas Nico

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.01 MB

english, 2019

44

Farnesoid X receptor and bile acids regulate vitamin A storage

Saeed, Ali, Yang, Jing, Heegsma, Janette, Groen, Albert K., van Mil, Saskia W. C., Paulusma, Coen C., Zhou, Lu, Wang, Bangmao, Faber, Klaas Nico

Journal:

Scientific Reports

Year:

2019

File:

PDF, 2.01 MB

2019

45

Reply to Letter to the Editor HEPâ20â0593

Roscam Abbing, Reinout L.P., Kuipers, Folkert, Paulusma, Coen C, Verkade, Henkjan J., Groen, Albert K., Oude Elferink, Ronald P.J., van, Stan F.J., de Graaf,

Journal:

Year:

2020

File:

PDF, 1.28 MB

2020

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