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51

Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study

James V. Lacey Jr., Hannah Yang, Mia M. Gaudet, Alison Dunning, Jolanta Lissowska, Mark E. Sherman, Beata Peplonska, Louise A. Brinton, Catherine S. Healey, Shahana Ahmed, Paul Pharoah, Douglas Easton

Journal:

Gynecologic Oncology

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

52

The genetics of ovarian cancer

Paul D.P Pharoah, Bruce A.J Ponder

Journal:

Best Practice & Research Clinical Obstetrics & Gynaecology

Year:

2002

Language:

english

File:

PDF, 230 KB

english, 2002

53

Gail et al risk prediction model adequately estimates breast cancer risk in groups of women but has lower accuracy for individual women

Journal:

Evidence-based Oncology

Year:

2002

Language:

english

File:

PDF, 82 KB

english, 2002

54

Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design

Helen I Field, Serena A Scollen, Craig Luccarini, Caroline Baynes, Jonathan Morrison, Alison M Dunning, Douglas F Easton, Paul DP Pharoah

Journal:

BMC Bioinformatics

Year:

2009

Language:

english

File:

PDF, 604 KB

english, 2009

55

Common variation inEMSYand risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs

Patrick R Benusiglio, Fabienne Lesueur, Craig Luccarini, Joan McIntosh, Robert N Luben, Paula Smith, Alison Dunning, Douglas F Easton, Bruce AJ Ponder, Paul D Pharoah

Journal:

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

56

Meta-analysis confirms BCL2 is an independent prognostic marker in breast cancer

Grace M Callagy, Mark J Webber, Paul DP Pharoah, Carlos Caldas

Journal:

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

57

TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer

Bruna, Alejandra, Greenwood, Wendy, Le Quesne, John, Teschendorff, Andrew, Miranda-Saavedra, Diego, Rueda, Oscar M., Sandoval, Jose L., Vidakovic, Ana Tufegdzic, Saadi, Amel, Pharoah, Paul, Stingl, Jo

Journal:

Nature Communications

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

58

Predict: a population-based validation of a prognostic model for early breast cancer that includes HER2

Gordon Wishart, Chris Bajdik, Ed Dicks, Elena Provenzano, Carlos Caldas, Paul Pharoah

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2012

Language:

english

File:

PDF, 35 KB

english, 2012

59

The inherited genetics of ovarian and endometrial cancer

Simon A Gayther, Paul DP Pharoah

Journal:

Current Opinion in Genetics & Development

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

60

Degenerate Oligonucleotide Primed-Polymerase Chain Reaction-Based Array Comparative Genomic Hybridization for Extensive Amplicon Profiling of Breast Cancers: A New Approach for the Molecular Analysis of Paraffin-Embedded Cancer Tissue

Yataro Daigo, Suet-Feung Chin, Kylie L. Gorringe, Lynda G. Bobrow, Bruce A.J. Ponder, Paul D.P. Pharoah, Carlos Caldas

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 1.32 MB

english, 2001

61

Prediction of pathogenic mutations in patients with early-onset breast cancer by family history

Fiona Lalloo, Jennifer Varley, David Ellis, Anthony Moran, Lindsay O'Dair, Paul Pharoah, D Gareth R Evans

Journal:

Year:

2003

Language:

english

File:

PDF, 64 KB

english, 2003

62

Catastrophic failures of public health

Journal:

Year:

2004

Language:

english

File:

PDF, 44 KB

english, 2004

63

Low penetrance susceptibility genes for breast cancer

B. Ponder, Annika Auranen, Alison Dunning, Doug Easton, Katie Healey, Bettina Kuschel, Simon McBride, Paul Pharoah

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

64

Session 2 S2. Genetic susceptibility and predicting cancer risk in individuals

Paul D.P. Pharoah

Journal:

European Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

65

Association between KRAS rs61764370 and triple-negative breast cancer—a false positive?

Paul Pharoah, Antonis Antoniou, Andrew Berchuck, Georgia Chenevix-Trench, Simon Gayther, Ellen Goode, Roger Milne, Tom Sellers, Jonathan Tyrer

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 151 KB

english, 2011

66

A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma

José Carlos Machado, Céu Figueiredo, Paulo Canedo, Paul Pharoah, Ralph Carvalho, Sérgio Nabais, Catarina Castro Alves, Maria Luisa Campos, Leen-jan Van Doorn, Carlos Caldas, Raquel Seruca, Fátima Carn

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

67

Standardized Total Average Toxicity Score: A Scale- and Grade-Independent Measure of Late Radiotherapy Toxicity to Facilitate Pooling of Data From Different Studies

Gillian C. Barnett, Catharine M.L. West, Charlotte E. Coles, Paul D.P. Pharoah, Christopher J. Talbot, Rebecca M. Elliott, George A. Tanteles, R. Paul Symonds, Jennifer S. Wilkinson, Alison M. Dunning

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 913 KB

english, 2012

68

No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: Results from the RAPPER study

Gillian C. Barnett, Charlotte E. Coles, Neil G. Burnet, Paul D.P. Pharoah, Jennifer Wilkinson, Catharine M.L. West, Rebecca M. Elliott, Caroline Baynes, Alison M. Dunning

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

69

Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance

H Raza Ali, Sarah-Jane Dawson, Fiona M Blows, Elena Provenzano, Paul D Pharoah, Carlos Caldas

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 991 KB

english, 2011

70

O-41 Age specific breast cancer relative survival in the East of England

Alaa M.G. Ali, Gordon Wishart, David Greenberg, Paul Pharoah

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

71

O-19 Comparison of imputation methods for missing immunohistochemical markers in a study of breast cancer prognosis

Alaa M.G. Ali, S.-J. Dawson, F. Blows, E. Provenzano, C. Caldas, Paul Pharoah

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

72

Role of genetic polymorphisms and ovarian cancer susceptibility

Peter A. Fasching, Simon Gayther, Leigh Pearce, Joellen M. Schildkraut, Ellen Goode, Falk Thiel, Georgia Chenevix-Trench, Jenny Chang-Claude, Shan Wang-Gohrke, Susan Ramus, Paul Pharoah, Andrew Berchu

Journal:

Molecular Oncology

Year:

2009

Language:

english

File:

PDF, 206 KB

english, 2009

73

Reply

Paul Pharoah, Carlos Caldas, David Huntsman, Parry Guildford

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

74

Interleukin 1B and Interleukin 1RN Polymorphisms Are Associated With Increased Risk of Gastric Carcinoma

José Carlos Machado, Paul Pharoah, Sónia Sousa, Ralph Carvalho, Carla Oliveira, Céu Figueiredo, António Amorim, Raquel Seruca, Carlos Caldas, Fátima Carneiro, Manuel Sobrinho-Simões

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

75

Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families

Paul D.P. Pharoah, Parry Guilford, Carlos Caldas, The International Gastric Cancer Linkage Consortium

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 566 KB

english, 2001

76

A Prospective, Multicenter Study to Evaluate a Novel, Nonendoscopic Screening Device for Barrett's Esophagus in the Community Setting

Sudarshan R. Kadri, Pierre Lao–Sirieix, Maria O'Donovan, Irene Debiram–Beecham, Madhumita Das, Jon Emery, Alex Boussioutas, Helen Morris, Fiona M. Walter, Jane M. Blazeby, Paul Pharoah, Richard H. Har

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 93 KB

english, 2010

77

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

Jean E Abraham, Mel J Maranian, Inmaculada Spiteri, Roslin Russell, Susan Ingle, Craig Luccarini, Helena M Earl, Paul PD Pharoah, Alison M Dunning, Carlos Caldas

Journal:

BMC Medical Genomics

Year:

2012

Language:

english

File:

PDF, 511 KB

english, 2012

78

A genome-wide association scan on estrogen receptor-negative breast cancer

Jingmei Li, Keith Humphreys, Hatef Darabi, Gustaf Rosin, Ulf Hannelius, Tuomas Heikkinen, Kristiina Aittomäki, Carl Blomqvist, Paul DP Pharoah, Alison M Dunning, Shahana Ahmed, Maartje J Hooning, Anto

Journal:

Breast Cancer Research

Year:

2010

Language:

english

File:

PDF, 2.01 MB

english, 2010

79

Diabetes Mellitus and Its Correlates in an Iranian Adult Population

Golozar, Asieh, Khademi, Hooman, Kamangar, Farin, Poutschi, Hossein, Islami, Farhad, Abnet, Christian C., Freedman, Neal D., Taylor, Philip R., Pharoah, Paul, Boffetta, Paolo, Brennan, Paul J., Dawsey

Journal:

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

80

The admixture maximum likelihood test to test for association between rare variants and disease phenotypes

Jonathan P Tyrer, Qi Guo, Douglas F Easton, Paul DP Pharoah

Journal:

BMC Bioinformatics

Year:

2013

Language:

english

File:

PDF, 198 KB

english, 2013

81

Inherited Genetic Susceptibility to Breast Cancer

Ghoussaini, Maya, Pharoah, Paul D.P., Easton, Douglas F.

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 1.41 MB

english, 2013

82

Kernel canonical correlation analysis for assessing gene–gene interactions and application to ovarian cancer

Larson, Nicholas B, Jenkins, Gregory D, Larson, Melissa C, Vierkant, Robert A, Sellers, Thomas A, Phelan, Catherine M, Schildkraut, Joellen M, Sutphen, Rebecca, Pharoah, Paul P D, Gayther, Simon A, We

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 669 KB

english, 2014

83

Personalized screening for cancers: should we consider polygenic profiling?

Pashayan, Nora, Guo, Qi, Pharoah, Paul DP

Journal:

Personalized Medicine

Year:

2013

Language:

english

File:

PDF, 759 KB

english, 2013

84

Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

Horne, Hisani N., Sherman, Mark E., Garcia-Closas, Montserrat, Pharoah, Paul D., Blows, Fiona M., Yang, Xiaohong R., Hewitt, Stephen M., Conway, Catherine M., Lissowska, Jolanta, Brinton, Louise A., P

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 271 KB

english, 2014

85

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Pharoah, Paul D P, Tsai, Ya-Yu, Ramus, Susan J, Phelan, Catherine M, Goode, Ellen L, Lawrenson, Kate, Buckley, Melissa, Fridley, Brooke L, Tyrer, Jonathan P, Shen, Howard, Weber, Rachel, Karevan, Rod,

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

86

Predict: a population-based prognostic model for early breast cancer that includes Ki67

Wishart, Gordon, Ali, Raza, Blows, Fiona, Pharoah, Paul

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2013

Language:

english

File:

PDF, 42 KB

english, 2013

87

23. Inclusion of KI67 significantly improves performance of the predict prognostication and prediction model for early breast cancer

Wishart, Gordon, Rakha, Emad, Green, Andrew, Ellis, Ian, Pharoah, Paul

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

88

Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study

Sudarshan R Kadri, Pierre Lao-Sirieix, Maria O'Donovan, Irene Debiram, Madhumita Das, Jane M Blazeby, Jon Emery, Alex Boussioutas, Helen Morris, Fiona M Walter, Paul Pharoah, Richard H Hardwick and Re

Journal:

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

89

Incorporating genomics into breast and prostate cancer screening: assessing the implications

Chowdhury, Susmita, Dent, Tom, Pashayan, Nora, Hall, Alison, Lyratzopoulos, Georgios, Hallowell, Nina, Hall, Per, Pharoah, Paul, Burton, Hilary

Journal:

Genetics in Medicine

Year:

2013

Language:

english

File:

PDF, 702 KB

english, 2013

90

Long-term erectile function following permanent seed brachytherapy treatment for localized prostate cancer

Ong, Wee Loon, Hindson, Benjamin R., Beaufort, Catherine, Pharoah, Paul, Millar, Jeremy L.

Journal:

Radiotherapy and Oncology

Year:

2014

Language:

english

File:

PDF, 492 KB

english, 2014

91

Public health implications from COGS and potential for risk stratification and screening

Burton, Hilary, Chowdhury, Susmita, Dent, Tom, Hall, Alison, Pashayan, Nora, Pharoah, Paul

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 129 KB

english, 2013

92

Genetics: How to validate a breast cancer prognostic signature

Pharoah, Paul D., Caldas, Carlos

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2010

Language:

english

File:

PDF, 152 KB

english, 2010

93

Polygenes, Risk Prediction, and Targeted Prevention of Breast Cancer

Pharoah, Paul D.P., Antoniou, Antonis C., Easton, Douglas F., Ponder, Bruce A.J.

Journal:

Boston Medical and Surgical Journal

Year:

2008

Language:

english

File:

PDF, 214 KB

english, 2008

94

Polygenic susceptibility to breast cancer: current state-of-the-art

Ghoussaini, Maya, Pharoah, Paul DP

Journal:

Future Oncology

Year:

2009

Language:

english

File:

PDF, 506 KB

english, 2009

95

Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier

Martins, Filipe C, Santiago, Ines, Trinh, Anne, Xian, Jian, Guo, Anne, Sayal, Karen, Jimenez-Linan, Mercedes, Deen, Suha, Driver, Kristy, Mack, Marie, Aslop, Jennifer, Pharoah, Paul D, Markowetz, Flor

Journal:

Year:

2014

Language:

english

File:

PDF, 3.28 MB

english, 2014

96

The effect of rare variants on inflation of the test statistics in case–control analyses

Pirie, Ailith, Wood, Angela, Lush, Michael, Tyrer, Jonathan, Pharoah, Paul DP

Journal:

BMC Bioinformatics

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

97

Molecular genetics and the assessment of human cancers

Caldas, Carlos, Pharoah, Paul D.P.

Journal:

Expert Reviews in Molecular Medicine

Year:

1999

Language:

english

File:

PDF, 294 KB

english, 1999

98

Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition

Moir-Meyer, Gemma L., Pearson, John F., Lose, Felicity, Scott, Rodney J., McEvoy, Mark, Attia, John, Holliday, Elizabeth G., Pharoah, Paul D., Dunning, Alison M., Thompson, Deborah J., Easton, Douglas

Journal:

Year:

2015

Language:

english

File:

PDF, 248 KB

english, 2015

99

Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer

Wishart, Gordon C, Rakha, Emad, Green, Andrew, Ellis, Ian, Ali, Hamid, Provenzano, Elena, Blows, Fiona M, Caldas, Carlos, Pharoah, Paul DP

Journal:

Year:

2014

Language:

english

File:

PDF, 319 KB

english, 2014

100

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

Lei, Jieping, Rudolph, Anja, Moysich, Kirsten B, Rafiq, Sajjad, Behrens, Sabine, Goode, Ellen L, Pharoah, Paul PD, Seibold, Petra, Fasching, Peter A, Andrulis, Irene L, Kristensen, Vessela N, Couch, F

Journal:

Breast Cancer Research

Year:

2015

Language:

english

File:

PDF, 678 KB

english, 2015