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51

Pharmacogenetics and pharmacogenomics

Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 46 KB

english, 2001

52

Relevance of induction of human drug-metabolizing enzymes: pharmacological and toxicological implications

B. K. PARK, N. R. KITTERINGHAM, M. PIRMOHAMED, G. T. TUCKER

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 357 KB

english, 1996

53

The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole

HELEN J. GILL, JAMES L. MAGGS, STEPHEN MADDEN, MUNIR PIRMOHAMED, B. KEVIN PARK

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 279 KB

english, 1996

54

Safety assessment of peroxide antimalarials: clinical and chemical perspectives

B. Kevin Park, Paul M. O’Neill, James L. Maggs, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 405 KB

english, 1998

55

Carbamazepine is not a substrate for P-glycoprotein

Andrew Owen, Munir Pirmohamed, Justice N. Tettey, Paul Morgan, David Chadwick, B. Kevin Park

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

56

Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity

Ana Alfirevic, Anne C. Stalford, F. Javier Vilar, Ed G. L. Wilkins, B. Kevin Park, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 261 KB

english, 2003

57

Adverse drug reactions: back to the future

Munir Pirmohamed, B. Kevin Park

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

58

The BPS web site for Continuing Professional Development in Clinical Pharmacology and Therapeutics

John Mucklow, Nigel Baber, Simon Maxwell, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 47 KB

english, 2003

59

Polymorphisms in the TNF-α and TNF-receptor genes in patients with coronary artery disease

R. A. Allen, E. M. Lee, D. H. Roberts, B. K. Park, M. Pirmohamed

Journal:

European Journal of Clinical Investigation

Year:

2001

Language:

english

File:

PDF, 872 KB

english, 2001

60

Communication regarding adverse drug reactions between secondary and primary care: a postal questionnaire survey of general practitioners

C. F. Green, D. R. Mottram, M. Pirmohamed, R. Horner, P. H. Rowe

Journal:

Journal of Clinical Pharmacy and Therapeutics

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

61

Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial

Seren Haf Roberts, Emma Bedson, Dyfrig Hughes, Keith Lloyd, Stuart Moat, Munir Pirmohamed, Gary Slegg, Richard Tranter, Rhiannon Whitaker, Clare Wilkinson, Ian Russell

Journal:

Year:

2007

Language:

english

File:

PDF, 319 KB

english, 2007

62

Correction: Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial

Seren Haf Roberts, Emma Bedson, Dyfrig A Hughes, Keith R Lloyd, David B Menkes, Stuart J Moat, Munir Pirmohamed, Gary P Slegg, Johannes Thome, Richard Tranter, Rhiannon Whitaker, Clare Wilkinson, Ian

Journal:

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

63

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

L Dickinson, M Chaponda, D Carr, JJ van Oosterhout, J Kumwenda, DG Lalloo, M Pirmohamed, R Heyderman, SH Khoo

Journal:

Journal of the International AIDS Society

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

64

A method for the rapid depletion of albumin and immunoglobulin from human plasma

Carrie Greenough, Rosalind E. Jenkins, Neil R. Kitteringham, Munir Pirmohamed, B. Kevin Park, Stephen R. Pennington

Journal:

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

65

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo

Rosalind E. Jenkins, Xiaoli Meng, Victoria L. Elliott, Neil R. Kitteringham, Munir Pirmohamed, B. Kevin Park

Journal:

PROTEOMICS - Clinical Applications

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

66

Off-label and unlicensed medicine use and adverse drug reactions in children: a narrative review of the literature

Jennifer Mason, Munir Pirmohamed, Tony Nunn

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 163 KB

english, 2012

67

Drug-drug interactions and adverse drug reactions: separating the wheat from the chaff

Munir Pirmohamed

Journal:

Wiener klinische Wochenschrift

Year:

2010

Language:

english

File:

PDF, 470 KB

english, 2010

68

Immunopharmacology of hypersensitivity reactions to drugs

Dean J. Naisbitt, Munir Pirmohamed, B. Kevin Park

Journal:

Current Allergy and Asthma Reports

Year:

2003

Language:

english

File:

PDF, 459 KB

english, 2003

69

Genetic variants of hepatic transporters and susceptibility to drug induced liver injury

Pallav Bhatnagar, Chris P. Day, Guruprasad Aithal, Munir Pirmohamed, William Bernal, Ann K. Daly

Journal:

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

70

Review article: cellular and molecular mechanisms of NSAID-induced peptic ulcers

C. MUSUMBA, D. M. PRITCHARD, M. PIRMOHAMED

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 223 KB

english, 2009

71

Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

Andrew Owen, Chris Goldring, Paul Morgan, David Chadwick, B. Kevin Park, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 130 KB

english, 2005

72

The quality of information on monitoring for haematological adverse drug reactions

R. E. Ferner, Jamie Coleman, Munir Pirmohamed, Simon A. Constable, Andrew Rouse

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

73

Induction of P-glycoprotein in lymphocytes by carbamazepine and rifampicin: the role of nuclear hormone response elements

Andrew Owen, Chris Goldring, Paul Morgan, B. Kevin Park, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 155 KB

english, 2006

74

The future prospects of pharmacogenetics in oral anticoagulation therapy

Farhad Kamali, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

75

Which drugs cause preventable admissions to hospital? A systematic review

R. L. Howard, A. J. Avery, S. Slavenburg, S. Royal, G. Pipe, P. Lucassen, M. Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

76

Warfarin: almost 60 years old and still causing problems

Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 65 KB

english, 2006

77

Herbal medicines and acute medical emergency admissions to hospital

Simon Constable, Andrew Ham, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

78

Effect of topiramate on acid–base balance: extent, mechanism and effects

Nasir Mirza, Anthony G. Marson, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 519 KB

english, 2009

79

Interpreting adverse drug reaction (ADR) reports as hospital patient safety incidents

Emma C. Davies, Christopher F. Green, David R. Mottram, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 628 KB

english, 2010

80

Emergency re-admissions to hospital due to adverse drug reactions within 1 year of the index admission

Emma C. Davies, Christopher F. Green, David R. Mottram, Philip H. Rowe, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

81

Hypersensitivity reactions to HIV therapy

Mas Chaponda, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

82

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

Steven Lane, Sameh Al-Zubiedi, Ellen Hatch, Ivan Matthews, Andrea L. Jorgensen, Panos Deloukas, Ann K. Daly, B. Kevin Park, Leon Aarons, Kayode Ogungbenro, Farhad Kamali, Dyfrig Hughes, Munir Pirmoham

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 3.52 MB

english, 2012

83

Reported paediatric adverse drug reactions in the UK 2000–2009

Daniel B. Hawcutt, Pramod Mainie, Andrew Riordan, Rosalind L. Smyth, Munir Pirmohamed

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1000 KB

english, 2012

84

Systemic illness with skin eruption, fever and positive lymphocyte transformation test in a patient on irbesartan

S. Constable, J. Farrell, D. Naisbitt, C. King, N. Leonard, M. Pirmohamed

Journal:

British Journal of Dermatology

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

85

Response 2 to pharmacogenetic screening to prevent carbamazepine-induced toxic epidermal necrolysis and Stevens–Johnson syndrome: a critical appraisal

A. Alfirevic, M. McCormack, M. Pirmohamed, G.L. Cavalleri

Journal:

British Journal of Dermatology

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

86

Deletion of exon 3 in the growth hormone receptor gene in adults with growth hormone deficiency: comparison of symptomatic and asymptomatic patients

O.R. Adetunji, J.C. Blair, M. Javadpour, A. Alfirevic, M. Pirmohamed, I.A. MacFarlane

Journal:

Clinical Endocrinology

Year:

2010

Language:

english

File:

PDF, 60 KB

english, 2010

87

Adverse drug reactions as a cause of admission to an acute medical assessment unit: a pilot study

C. F. Green, D. R. Mottram, P. H. Rowe, M. Pirmohamed

Journal:

Journal of Clinical Pharmacy and Therapeutics

Year:

2000

Language:

english

File:

PDF, 85 KB

english, 2000

88

Adverse drug reactions in hospital in-patients: a pilot study

E. C. Davies, C. F. Green, D. R. Mottram, M. Pirmohamed

Journal:

Journal of Clinical Pharmacy and Therapeutics

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

89

The use of opioids and laxatives, and incidence of constipation, in patients requiring neck-of-femur (NOF) surgery: a pilot study

E. C. Davies, C. F. Green, D. R. Mottram, M. Pirmohamed

Journal:

Journal of Clinical Pharmacy and Therapeutics

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

90

Adverse drug reactions causing admission to a paediatric hospital: a pilot study

R. M. Gallagher, K. A. Bird, J. R. Mason, M. Peak, P. R. Williamson, A. J. Nunn, M. A. Turner, M. Pirmohamed, R. L. Smyth

Journal:

Journal of Clinical Pharmacy and Therapeutics

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

91

Carbamazepine-induced acute liver failure as part of the DRESS syndrome

W-K Syn, D. J. Naisbitt, A. P. Holt, M. Pirmohamed, D. J. Mutimer

Journal:

International Journal of Clinical Practice

Year:

2005

Language:

english

File:

PDF, 1.83 MB

english, 2005

92

Important questions in Allergy: 1 – drug allergy/hypersensitivity

P. Demoly, W. Pichler, M. Pirmohamed, A. Romano

Journal:

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

93

The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes

Omar Janneh, Andrew Owen, Patrick G. Bray, David J. Back, Munir Pirmohamed

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 549 KB

english, 2010

94

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

HG Laverty, C Benson, EJ Cartwright, MJ Cross, C Garland, T Hammond, C Holloway, N McMahon, J Milligan, BK Park, M Pirmohamed, C Pollard, J Radford, N Roome, P Sager, S Singh, T Suter, W Suter, A Traf

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

95

Acceptance of Biomarker-Based Tests for Application in Clinical Practice: Criteria and Obstacles

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

96

The Phenotype Standardization Project: Improving Pharmacogenetic Studies of Serious Adverse Drug Reactions

Pirmohamed, M, Aithal, G P, Behr, E, Daly, A, Roden, D

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

97

Phenotype Standardization for Immune-Mediated Drug-Induced Skin Injury

Pirmohamed, M, Friedmann, P S, Molokhia, M, Loke, Y K, Smith, C, Phillips, E, La Grenade, L, Carleton, B, Papaluca-Amati, M, Demoly, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 340 KB

english, 2011

98

Characterization of p-Phenylenediamine–Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein

Jenkinson, Claire, Jenkins, Rosalind E, Aleksic, Maja, Pirmohamed, Munir, Naisbitt, Dean J, Park, B Kevin

Journal:

The Journal of Investigative Dermatology

Year:

2009

Language:

english

File:

PDF, 583 KB

english, 2009

99

Nilotinib concentration in cell lines and primary CD34+ chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters

Davies, A, Jordanides, N E, Giannoudis, A, Lucas, C M, Hatziieremia, S, Harris, R J, Jørgensen, H G, Holyoake, T L, Pirmohamed, M, Clark, R E

Journal:

Year:

2009

Language:

english

File:

PDF, 350 KB

english, 2009

100

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity

Dean J Naisbitt, Sally J Hough, Helen J Gill, Munir Pirmohamed, Neil R Kitteringham, B Kevin Park

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 388 KB

english, 1999