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1

Discovery of a New Class of Anilinoquinazoline Inhibitors with High Affinity and Specificity for the Tyrosine Kinase Domain of c-Src

Plé, Patrick A., Green, Tim P., Hennequin, Laurent F., Curwen, Jon, Fennell, Michael, Allen, Jack, Lambert-van der Brempt, Christine, Costello, Gerard

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 472 KB

english, 2004

2

Syndrome des gènes contigus TSC2/PKD1

Benoît, Gérard, Yonneau, Laurent, Ferlicot, Sophie, Yadaden, Tarik, Molinié, Vincent, Ples, Raluca, Lazure, Thierry

Journal:

Annales de Pathologie

Year:

2007

Language:

french

File:

PDF, 671 KB

french, 2007

3

Ring-chain tautomerism and other versatile behaviour of 1,4-diimino- and 1,2-phenylene derivatives of some C-substituted serinols

Carmen Maiereanu, Mircea Darabantu, Gérard Plé, Camelia Berghian, Eric Condamine, Yvan Ramondenc, Ion Silaghi-Dumitrescu, Sorin Mager

Journal:

Year:

2002

Language:

english

File:

PDF, 285 KB

english, 2002

4

Considerations about the chirality of the saturated six-membered rings with two or more heteroatoms

Ion Grosu, Sorin Mager, Gerard Plé, Roberto Martinez

Journal:

Year:

1996

Language:

english

File:

PDF, 344 KB

english, 1996

5

1,6-Dibromohexa-1,3,5-triene − Stereocontrolled Synthesis of Monosubstituted and Disubstituted Hexatrienes by Palladium-Catalysed Cross-Coupling Reactions

Pierre Villiers, Nicolas Vicart, Yvan Ramondenc, Gérard Plé

Journal:

European Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 481 KB

english, 2001

6

ChemInform Abstract: Preparation of Highly Functionalized Pyridylmagnesium Reagents for the Synthesis of Polyfunctional Pyridines.

Laurent Berillon, Anne Lepretre, Alain Turck, Nelly Ple, Guy Queguiner, Gerard Cahiez, Paul Knochel

Journal:

Year:

1999

File:

PDF, 26 KB

1999

7

ChemInform Abstract: The Synthesis, Stereochemistry, and NMR Spectra of Some New Spiro-1,3-dioxanes

Ion Grosu, Sorin Mager, Roberto Martinez, Brigida del Carmen Camacho, Gerard Ple, Clementina Mesaros

Journal:

Year:

1999

File:

PDF, 27 KB

1999

8

ChemInform Abstract: An Expeditious Synthesis of Ostopanic Acid, a Plant Anticancer Agent.

Dominique Castet-Caillabet, Yvan Ramondenc, Gerard Ple, Lucette Duhamel

Journal:

Year:

1999

File:

PDF, 24 KB

1999

9

ChemInform Abstract: Syntheses of Three New Lithio Hexavinylogation Reagents.

Pierre Villiers, David Soullez, Yvan Ramondenc, Gerard Ple

Journal:

Year:

2000

File:

PDF, 29 KB

2000

10

ChemInform Abstract: (1E,3E,5Z)-1,6-Dibromohexa-1,3,5-triene: Regio- and Stereocontrolled Mono Pallado-Catalyzed Cross-Coupling Reactions.

Pierre Villiers, Nicolas Vicart, Yvan Ramondenc, Gerard Ple

Journal:

Year:

2000

File:

PDF, 31 KB

2000

11

ChemInform Abstract: Synthesis and Stereochemistry of Novel Dibrominated 1,5-Dioxaspiro[5.5]undecane Derivatives.

Ion Grosu, Loic Toupet, Gerard Ple, Sorin Mager, Eugen Mesaros, Andreea Varga, Elena Bogdan

Journal:

Year:

2000

File:

PDF, 28 KB

2000

12

ChemInform Abstract: Synthesis and Stereochemistry of Some New 3,9-Diaryl-2,4,8,10-tetraoxaspiro[5.5]undecanes.

Ion Grosu, Sorin Mager, Gerard Ple, Eugen Mesaros, Csaba Gego, Anca Dulau

Journal:

Year:

2000

File:

PDF, 29 KB

2000

13

ChemInform Abstract: Synthesis and Stereochemistry of Some 1,3-Oxazolidine Systems Based on TRIS (α,α,α-Trimethylolaminomethane) and Related Aminopolyols Skeleton. Part 1. (Di)spiro-1,3-oxazolidines.

Mircea Darabantu, Gerard Ple, Ion Silaghi-Dumitrescu, Carmen Maiereanu, Istvan Turos, Ioan A. Silberg, Sorin Mager

Journal:

Year:

2000

File:

PDF, 34 KB

2000

14

ChemInform Abstract: Synthesis and Stereochemistry of Some 1,3-Oxazolidine Systems Based on TRIS (α,α,α-Trimethylolaminomethane) and Related Aminopolyols Skeleton. Part 2. 1-Aza-3,7-dioxabicyclo[3.3.0]octanes.

Mircea Darabantu, Gerard Ple, Carmen Maiereanu, Ion Silaghi-Dumitrescu, Yvan Ramondenc, Sorin Mager

Journal:

Year:

2000

File:

PDF, 38 KB

2000

15

ChemInform Abstract: Synthesis and Stereochemistry of Some New Spiro-1,3-perhydrooxazines.

Luminita Muntean, Ion Grosu, Gerard Ple, Sorin Mager, Ioan Silaghi-Dumitrescu

Journal:

Year:

2000

File:

PDF, 28 KB

2000

16

ChemInform Abstract: Synthesis and Stereochemistry of Some New 1,3-Dioxane Derivatives Obtained from 5-Aryl-2-furaldehydes.

Ion Grosu, Mirela Balog, Csaba Paisz, Gerard Ple, Florin Dan Irimie, Sorin Mager, Razvan Podea

Journal:

Year:

2001

File:

PDF, 27 KB

2001

17

ChemInform Abstract: A Novel Synthesis of AZT.

Christine Gauthier, Yvan Ramondenc, Gerard Ple

Journal:

Year:

2001

File:

PDF, 30 KB

2001

18

ChemInform Abstract: Synthesis and Stereochemistry of New Tetraspiro-1,3-dioxanes.

Dorina Opris, Ion Grosu, Loic Toupet, Gerard Ple, Anamaria Terec, Sorin Mager, Luminita Muntean

Journal:

Year:

2002

File:

PDF, 27 KB

2002

19

ChemInform Abstract: 1,6-Dibromohexa-1,3,5-triene — Stereocontrolled Synthesis of Monosubstituted and Disubstituted Hexatrienes by Palladium-Catalyzed Cross-Coupling Reactions.

Pierre Villiers, Nicolas Vicart, Yvan Ramondenc, Gerard Ple

Journal:

Year:

2002

Language:

english

File:

PDF, 40 KB

english, 2002

20

Synthesis and Stereochemistry of Some New 1,3-Dioxane Derivatives of 1,3-Diacetylbenzene.

Luminita Muntean, Monica Pop, Ion Grosu, Sorin Mager, Gerard Ple, Alexandria Nan, Elena Bogdan

Journal:

Year:

2003

File:

PDF, 85 KB

2003

21

Synthesis, Structural Analysis and Reactivity of 1,3-Oxathiane Derivatives

Anamaria Terec, Ion Grosu, Gerard Ple, Luminita Muntean, Sorin Mager

Journal:

Year:

2003

File:

PDF, 51 KB

2003

22

Palladium Catalyzed Cross-Coupling Reaction of Functional Organozinc Reagents with (2E,4E)- and (2E,4Z)-5-Bromopenta-2,4-dienals: Easy Access to Functional Conjugated Dienic Aldehydes.

Nicolas Vicart, Gerard-Simplice Saboukoulou, Yvan Ramondenc, Gerard Ple

Journal:

Year:

2003

File:

PDF, 96 KB

2003

23

Synthesis and Stereochemistry of Some New 1,3-Oxathiane Derivatives.

Mihaiela Stuparu, Ion Grosu, Luminita Muntean, Gerard Ple, Crina Cismas, Anamaria Terec, Alexandrina Nan, Sorin Mager

Journal:

Year:

2004

File:

PDF, 83 KB

2004

24

A Complex Problem of Diastereoisomerism: Synthesis and Stereochemistry of 1,4-Bis-{r-1-aza-c-5-ethyl-3,7-dioxabicyclo [3.3.0]octane-c-2-yl}-benzene (III).

Carmen Maiereanu, Loic Toupet, Eric Condamine, Ioan Silaghi-Dumitrescu, Gerard Ple, Yvan Ramondenc, Mircea Darabantu

Journal:

Year:

2005

File:

PDF, 13 KB

2005

25

ChemInform Abstract: The Synthesis of (D)-C-Mannopyranosides

Mariam Choumane, Aline Banchet, Nicolas Probst, Stephane Gerard, Karen Ple, Arnaud Haudrechy

Journal:

Year:

2011

File:

PDF, 18 KB

2011

26

Synthesis and Structure of New Macrocycles Including Spiro-1,3-Dioxane Units

Ion Grosu, Elena Bogdan, Gérard Plé, Loïc Toupet, Yvan Ramondenc, Eric Condamine, Valérie Peulon-Agasse, Mirela Balog

Journal:

European Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

27

3,7-Dioxa-1-azabicyclo[3.3.0]octanes Substituted at the C-5 Position − From Local to Global Stereochemistry

Mircea Darabantu, Carmen Maiereanu, Ioan Silaghi-Dumitrescu, Loïc Toupet, Eric Condamine, Yvan Ramondenc, Camelia Berghian, Gérard Plé, Nelly Plé

Journal:

European Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 531 KB

english, 2004

28

New [4.4]Cyclophane Diketals, Monoketones, and Diketones: Design, Synthesis, and Structural Analysis

Niculina Bogdan, Ion Grosu, Eric Condamine, Loïc Toupet, Yvan Ramondenc, Ioan Silaghi-Dumitrescu, Gérard Plé, Elena Bogdan

Journal:

European Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 527 KB

english, 2007

29

Synthesis and Stereochemistry of Some 1,3-Dioxane Diacetals of o-Phthaldialdehyde

Ion Grosu, Sorin Mager, Gerard Plé, Nelly Plé, Alfredo Toscano, Eugen Mesaros, Roberto Martinez

Journal:

European Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 662 KB

english, 1997

30

Application of modified selective polarization transfer experiments to the structural analysis of β-silylated silyl enol ethers by 1H, 13C and 29Si NMR

Vincent Baudrillard, Daniel Davoust, Gerard Ple

Journal:

Magnetic Resonance in Chemistry

Year:

1994

Language:

english

File:

PDF, 466 KB

english, 1994

31

Synthesis and stereochemistry of some dispiro-1,3-dioxanes with axial and helical chirality

Ion Grosu, Sorin Mager, Gerard Plé, Eugen Mesaros

Journal:

Year:

1996

Language:

english

File:

PDF, 661 KB

english, 1996

32

New heterocyclic analogues of 4-(2-chloro-5-methoxyanilino)quinazolines as potent and selective c-Src kinase inhibitors

Bernard Barlaam, Mike Fennell, Hervé Germain, Tim Green, Laurent Hennequin, Rémy Morgentin, Annie Olivier, Patrick Plé, Michel Vautier, Gerard Costello

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

33

Pentaspiranes and hexaspiranes with 1,3-dioxane or 1,3-oxathiane rings: synthesis and stereochemistry

Anamaria Terec, Ion Grosu, Eric Condamine, Livain Breau, Gérard Plé, Yvan Ramondenc, Fernande D Rochon, Valérie Peulon-Agasse, Dorina Opris

Journal:

Year:

2004

Language:

english

File:

PDF, 1.09 MB

english, 2004

34

Synthesis and structural analysis of new macrocycles exhibiting 3,9-dimethyl-3,9-diaryl-2,4,8,10-tetraoxaspiro[5.5]undecane units

Mirela Balog, Ion Grosu, Gérard Plé, Yvan Ramondenc, Loı̈c Toupet, Eric Condamine, Catherine Lange, Corinne Loutelier-Bourhis, Valérie Peulon-Agasse, Elena Bogdan

Journal:

Year:

2004

Language:

english

File:

PDF, 1.21 MB

english, 2004

35

Pd-catalyzed regio and stereocontrolled mono and bis-coupling reactions of 1-bromo-6-chlorohexa-1,3,5-triene: synthesis of a naturally occurring tetraenynone

Wissam Bentoumi, Jérôme Helhaik, Gérard Plé, Yvan Ramondenc

Journal:

Year:

2009

Language:

english

File:

PDF, 195 KB

english, 2009

36

A new series of rod-like conjugated molecules with a pyrazine or a bipyrazine core. Synthesis and light emitting properties

Nordine Hebbar, Catherine Fiol-Petit, Yvan Ramondenc, Gérard Plé, Nelly Plé

Journal:

Year:

2011

Language:

english

File:

PDF, 738 KB

english, 2011

37

Synthesis and Stereochemistry of Some 1,3-Oxazolidine Systems Based on TRIS (α,α,α-Trimethylolaminomethane) and Related Aminopolyols Skeleton. Part 1: (Di)spiro-1,3-oxazolidines

Mircea Darabantu, Gérard Plé, Ion Silaghi-Dumitrescu, Carmen Maiereanu, Istvan Turos, Ioan A Silberg, Sorin Mager

Journal:

Year:

2000

Language:

english

File:

PDF, 238 KB

english, 2000

38

Synthesis, stereochemistry and ring–chain tautomerism of some new spiro-1,3-oxathianes

Anamaria Terec, Ion Grosu, Luminita Muntean, Loı̈c Toupet, Gérard Plé, Crina Socaci, Sorin Mager

Journal:

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

39

Synthesis and stereochemistry of some heterocyclic saturated compounds based on l-p-nitrophenylserinol skeleton (I). Ring-chain tautomerism of some schiff bases of l-p-nitrophenylserinol

Mircea Darabantu, Gerard Ple, Sorin Mager, Eleonora Cotora, Luiza Gaina, Loredana Costas, Adrian Mates

Journal:

Year:

1997

Language:

english

File:

PDF, 975 KB

english, 1997

40

Synthesis and stereochemistry of some heterocyclic saturated compounds based on l-p-nitrophenylserinol skeleton (III). 1,3-Dioxanic Schiff bases

Mircea Darabantu, Gerard Ple, Sorin Mager, Camelia Puscas, Eleonora Cotora

Journal:

Year:

1997

Language:

english

File:

PDF, 735 KB

english, 1997

41

Synthesis and stereochemistry of some heterocyclic saturated compounds based on l-p-Nitrophenylserinol skeleton (II). 1-Aza-3,7-dioxabicyclo[3.3.0]octanes

Mircea Darabantu, Gerard Plè, Sorin Mager, Luiza Gaina, Eleonora Cotora, Adrian Mates, Loredana Costas

Journal:

Year:

1997

Language:

english

File:

PDF, 951 KB

english, 1997

42

Synthesis and Stereochemistry of Some New Chiral Spiro-1,3-Dioxanes

Ion Grosu, Gerard Plé, Sorin Mager, Roberto Martinez, Clementina Mesaros, Brigida del Carmen Camacho

Journal:

Year:

1997

Language:

english

File:

PDF, 1.68 MB

english, 1997

43

Study on the atropisomerism of some new 2-aryl-1,3-dioxanes

Ion Grosu, Gerard Plé, Sorin Mager, Eugen Mesaros, Anca Dulau, Csaba Gego

Journal:

Year:

1998

Language:

english

File:

PDF, 402 KB

english, 1998

44

An expeditious synthesis of ostopanic acid, a plant anticancer agent

Dominique Castet-Caillabet, Yvan Ramondenc, Gérard Plé, Lucette Duhame

Journal:

Year:

1999

Language:

english

File:

PDF, 269 KB

english, 1999

45

Syntheses of three new lithio hexavinylogation reagents

Pierre Villiers, David Soullez, Yvan Ramondenc, Gérard Plé

Journal:

Year:

1999

Language:

english

File:

PDF, 514 KB

english, 1999

46

Terminally substituted linear conjugated polyenes: Precursors of molecular wires.

Lucette Duhamel, Pierre Duhamel, Gérard Plé, Yvan Ramondenc

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 140 KB

english, 1993

47

Cyclization of methyl α-bromocrotonate to a pentasubstituted cyclopropane.

Lucette Duhamel, Olivier Peschard, Gérard Plé

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 214 KB

english, 1991

48

Action des cetenes Sur les diamino-1,2 ethylenes

Lucette Duhamel, Pierre Duhamel, Gérard Plé

Journal:

Tetrahedron Letters

Year:

1974

File:

PDF, 160 KB

1974

49

Sels D′α-di-immonium. Action des reactifs nucleophiles . acces aux ynediamines .

Lucette Duhamel, Pierre Duhamel, Gérard Plé

Journal:

Tetrahedron Letters

Year:

1972

File:

PDF, 174 KB

1972

50

Phosphoramides ω bromes synthese d'ethylene et propylene diamines

Philippe Savignac, Michel Dreux, Jacques Chenault, Gérard Plé

Journal:

Tetrahedron Letters

Year:

1971

File:

PDF, 173 KB

1971

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