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51

Polymorphic Analysis of the Human MHC-Linked Heat Shock Protein 70 (HSP70-2) and HSP70-Hom Genes in Insulin-Dependent Diabetes Mellitus (IDDM)

F. POCIOT, K. S. RØNNINGEN, J. NERUP

Journal:

Scandinavian Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 474 KB

english, 1993

52

Functional Analysis of a New Polymorphism in the Human TNF α Gene Promoter

F. POCIOT, S. D'ALFONSO, S. COMPASSO, R. SCORZA, P. M. RICHIARDI

Journal:

Scandinavian Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 349 KB

english, 1995

53

Identification of a Type 1 Diabetes-Associated CD4 Promoter Haplotype with High Constitutive Activity

O. P. Kristiansen, A. E. Karlsen, Z. M. Larsen, J. Johannesen, F. Pociot, T. Mandrup-Poulsen, The Danish IDDM Epidemiology, Genetics Group &amp, The Danish Study Group of IDDM in Childhood

Journal:

Scandinavian Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 136 KB

english, 2004

54

Identification and Characterization of Secretagogin Promoter Activity

K. V. Skovhus, R. Bergholdt, C. Erichsen, T. Sparre, J. Nerup, A. E. Karlsen, F. Pociot

Journal:

Scandinavian Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

55

Variation within the PPARG gene is associated with residual beta-cell function and glycemic control in children and adolescents during the first year of clinical type 1 diabetes

Sven Pörksen, Lotte B Nielsen, Henrik B Mortensen, Thomas Danne, Mirjana Kocova, Luis Castaño, Flemming Pociot, Philip Hougaard, Claus T Ekstrøm, Steen Gammeltoft, Mikael Knip, Lars Hansen, the Hvidør

Journal:

Pediatric Diabetes

Year:

2008

Language:

english

File:

PDF, 129 KB

english, 2008

56

Hypoglycemia, S-ACE and ACE genotypes in a Danish nationwide population of children and adolescents with type 1 diabetes

Jesper Johannesen, Jannet Svensson, Regine Bergholdt, Stefanie Eising, Hanne Gramstrup, Erik Frandsen, Jens Dick-Nielsen, Lars Hansen, Flemming Pociot, Henrik B Mortensen, The Danish Society for Diabe

Journal:

Pediatric Diabetes

Year:

2011

Language:

english

File:

PDF, 502 KB

english, 2011

57

IRS1, KCNJ11, PPARγ2 and HNF-1α: do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes?

A. Johansen, D. P. Jensen, R. Bergholdt, H. B. Mortensen, F. Pociot, J. Nerup, T. Hansen, O. Pedersen, The Danish Society of Childhood Diabetes

Journal:

Diabetes, Obesity and Metabolism

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

58

Results of the MHC Fine Mapping Workshop

S. S. Rich, B. Akolkar, P. Concannon, H. Erlich, J. Hilner, C. Julier, G. Morahan, J. Nerup, C. Nierras, F. Pociot, J. A. Todd

Journal:

Diabetes, Obesity and Metabolism

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

59

Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data

C. Brorsson, N. T. Hansen, K. Lage, R. Bergholdt, S. Brunak, F. Pociot, Diabetes Genetics Consortium

Journal:

Diabetes, Obesity and Metabolism

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

60

Current status and the future for the genetics of type I diabetes

Rich, S S, Akolkar, B, Concannon, P, Erlich, H, Hilner, J E, Julier, C, Morahan, G, Nerup, J, Nierras, C, Pociot, F

Journal:

Genes and Immunity

Year:

2009

Language:

english

File:

PDF, 285 KB

english, 2009

61

Overview of the Type I Diabetes Genetics Consortium

Rich, S S, Akolkar, B, Concannon, P, Erlich, H, Hilner, J E, Julier, C, Morahan, G, Nerup, J, Nierras, C, Pociot, F

Journal:

Genes and Immunity

Year:

2009

Language:

english

File:

PDF, 177 KB

english, 2009

62

Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex

Viken, M K, Blomhoff, A, Olsson, M, Akselsen, H E, Pociot, F, Nerup, J, Kockum, I, Cambon-Thomsen, A, Thorsby, E, Undlien, D E

Journal:

Genes and Immunity

Year:

2009

Language:

english

File:

PDF, 267 KB

english, 2009

63

Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the Type I Diabetes Genetics Consortium

Morahan, G, McKinnon, E, Berry, J, Browning, B, Julier, C, Pociot, F, James, I

Journal:

Genes and Immunity

Year:

2009

Language:

english

File:

PDF, 283 KB

english, 2009

64

No association of the IRS1 and PAX4 genes with type I diabetes

Bergholdt, R, Brorsson, C, Boehm, B, Morahan, G, Pociot, F

Journal:

Genes and Immunity

Year:

2009

Language:

english

File:

PDF, 280 KB

english, 2009

65

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

Bennett, S.T., Lucassen, A.M., Gough, S.C.L., Powell, E.E., Undlien, D.E., Pritchard, L.E., Merriman, M.E., Kawaguchi, Y., Dronsfield, M.J., Pociot, F.

Journal:

Nature Genetics

Year:

1995

File:

PDF, 993 KB

1995

66

Cytokine gene polymorphism in human disease: on-line databases

Bidwell, J, Keen, L, Gallagher, G, Kimberly, R, Huizinga, T, McDermott, M F, Oksenberg, J, McNicholl, J, Pociot, F, Hardt, C

Journal:

Genes and Immunity

Year:

1999

Language:

english

File:

PDF, 146 KB

english, 1999

67

CTLA-4 in autoimmune diseases – a general susceptibility gene to autoimmunity?

Kristiansen, O P, Larsen, Z M, Pociot, F

Journal:

Genes and Immunity

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

68

Characterization of new polymorphisms in the 5′UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level

Bergholdt, R, Larsen, Z M, Andersen, N A, Johannesen, J, Kristiansen, O P, Mandrup-Poulsen, T, Nerup, J, Pociot, F, DSGD,, DIEGG,

Journal:

Genes and Immunity

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

69

Cytokine gene polymorphism in human disease: on-line databases, Supplement 1

Bidwell, J, Keen, L, Gallagher, G, Kimberly, R, Huizinga, T, McDermott, M F, Oksenberg, J, McNicholl, J, Pociot, F, Hardt, C

Journal:

Genes and Immunity

Year:

2001

Language:

english

File:

PDF, 399 KB

english, 2001

70

No evidence for linkage in the promoter region of the inducible nitric oxide synthase gene (NOS2) in a Danish type 1 diabetes population

Johannesen, J, Pociot, F, Kristiansen, O P, Karlsen, A E, Nerup, J, , D I E G G, , D S G D

Journal:

Genes and Immunity

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

71

No evidence of a functionally significant polymorphism of the BCL2 gene in Danish, Finnish and Basque type 1 diabetes families

Heding, P E, Karlsen, A E, Veijola, R, Nerup, J, Pociot, F

Journal:

Genes and Immunity

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

72

Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32.3 producing susceptibility to type 1 diabetes

Field, L L, Larsen, Z, Pociot, F, Nerup, J, Tobias, R, Bonnevie-Nielsen, V

Journal:

Genes and Immunity

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

73

Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLA-DQB1, -DQA1 and –DRB1

Johansson, S, Lie, B A, Todd, J A, Pociot, F, Nerup, J, Cambon-Thomsen, A, Kockum, I, Akselsen, H E, Thorsby, E, Undlien, D E

Journal:

Genes and Immunity

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

74

Genetics of type 1 diabetes mellitus

Pociot, F, McDermott, M F

Journal:

Genes and Immunity

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

75

Characterization of a nuclear-factor-kappa B (NFκB) genetic marker in type 1 diabetes (T1DM) families

Gylvin, T, Bergholdt, R, Nerup, J, Pociot, F

Journal:

Genes and Immunity

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

76

Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB103 and DRB104 haplotypes

Blomhoff, A, Olsson, M, Johansson, S, Akselsen, H E, Pociot, F, Nerup, J, Kockum, I, Cambon-Thomsen, A, Thorsby, E, Undlien, D E

Journal:

Genes and Immunity

Year:

2006

Language:

english

File:

PDF, 659 KB

english, 2006

77

Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia

Nolsøe, R L, Kelly, J A, Pociot, F, Moser, K L, Kristiansen, O P, Mandrup-Poulsen, T, Harley, J B

Journal:

Genes and Immunity

Year:

2005

Language:

english

File:

PDF, 163 KB

english, 2005

78

Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance

Nolsøe, R L, Hamid, Y H, Pociot, F, Paulsen, S, Andersen, K M, Borch-Johnsen, K, Drivsholm, T, Hansen, T, Pedersen, O, Mandrup-Poulsen, T

Journal:

Genes and Immunity

Year:

2006

Language:

english

File:

PDF, 117 KB

english, 2006

79

Mutation Scan of a Type 1 Diabetes Candidate Gene : The Human Interleukin-18 Binding Protein Gene

RÚNA L. NOLSØE, FLEMMING POCIOT, DANIELA NOVICK, MENACHEM RUBINSTEIN, SOO-HYUN KIM, CHARLES A. DINARELLO, THOMAS MANDRUP-POULSEN

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 191 KB

2003

80

The Type 1 Diabetes Genetics Consortium

STEPHEN S. RICH, PATRICK CONCANNON, HENRY ERLICH, CECILE JULIER, GRANT MORAHAN, JORN NERUP, FLEMMING POCIOT, JOHN A. TODD

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

81

Different islet protein expression profiles during spontaneous diabetes development vs. allograft rejection in BB-DP rats

Christensen, Ulla Bjerre, Larsen, Peter Mose, Fey, Stephen, Karlsen, Allan E., Pociot, Flemming, Nerup, JØrn, Sparre, Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

82

Application of genomics and proteomics in Type 1 diabetes pathogenesis research

Sparre, Thomas, Bergholdt, Regine, Nerup, Jørn, Pociot, Flemming

Journal:

Expert Review of Molecular Diagnostics

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

83

Genetic Susceptibility Markers in Danish Patients with Type 1 (Insulin-Dependent) Diabetes-Evidence for Polygenecity in Man

Pociot, Flemming, Rosnningen, Kjersti S., Bergholdt, Regine, Lorenzen, Tove, Johannesen, Jesper, Ye, Ke, Dinarello, Charles A., Nerup, Josrn

Journal:

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

84

Nicotinamide treatment in the prevention of insulin-dependent diabetes mellitus

Thomas Mandrup-Poulsen, Jesper I. Reimers, Henrik U. Andersen, Flemming Pociot, Allan E. Karlsen, Ulla Bjerre, Jørn Nerup

Journal:

Diabetes/Metabolism Research and Reviews

Year:

1993

Language:

english

File:

PDF, 1.56 MB

english, 1993

85

IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

T., Sparre, Christensen, U. Bjerre, Larsen, P. Mose, S., Fey, K., Wrzesinski, P., Roepstorff, T., Mandrup-Poulsen, F., Pociot, A., Karlsen, J., Nerup

Journal:

Year:

2002

Language:

english

File:

PDF, 219 KB

english, 2002

86

Genome-Wide Association Scan for Type 1 Diabetes Susceptibility Genes in a Danish Population

Caroline Brorsson, Elzbieta Swiergala, Kristoffer Rapacki, Regine Bergholdt, Shaun Purcell, Leigh Field, Flemming Pociot

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

87

Sa.74. The Faroese, a Genetic Isolate with a Strong Founder Effect, Allows the Identification of Type 1 Diabetes Susceptibility Regions

Runa Nolsoe, Jogvan Roin, Marja Deckert, Regine Bergholdt, Jennifer Kelly, Caroline Brorsson, John Harley, Sjurdur Olsen, Flemming Pociot, Thomas Mandrup-Poulsen

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 36 KB

english, 2008

88

Sa.79. Identification of T1D Genes in the MHC Region by a Novel Approach Combining Genetic Data with Information on Functional Pathways

Caroline Brorsson, Niclas Hansen, Kasper Lage, Regine Bergholdt, Søren Brunak, Flemming Pociot

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

89

NO ASSOCIATION OR LINKAGE TO IDDM OF AN INTERFERON REGULATORY FACTOR-1 GENE POLYMORPHISM IN A DANISH POPULATION

J. JOHANNESEN, A. E. KARLSEN, J. NERUP, F. POCIOT, THE DANISH STUDY GROUP FOR DIABETES IN CHILDHOOD

Journal:

International Journal of Immunogenetics

Year:

1997

Language:

english

File:

PDF, 41 KB

english, 1997

90

A Taql polymorphism in the human interleukin-1β (IL-1β) gene correlates with IL-1β secretion in vitro

F. POCIOT, J. MØLVIG, L. WOGENSEN, H. WORSAAE, J. NERUP

Journal:

European Journal of Clinical Investigation

Year:

1992

Language:

english

File:

PDF, 719 KB

english, 1992

91

TUMOUR NECROSIS FACTOR MICROSATELLITE ALLELES IN AN ITALIAN POPULATION

E. Ciusani, A. Salmaggi, F. Pociot, A. Nespolo, M. Sandberg-Wollheim

Journal:

International Journal of Immunogenetics

Year:

1997

Language:

english

File:

PDF, 357 KB

english, 1997

92

Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy

Julie Anne Overgaard, Henning Gram Hansen, Maria Lajer, Lykke Pedersen, Lise Tarnow, Peter Rossing, James N McGuire, Flemming Pociot

Journal:

Proteome Science

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

93

BetaSys Volume 13 || Nanotoxicity

Booß-Bavnbek, Bernhelm, Klösgen, Beate, Larsen, Jesper, Pociot, Flemming, Renström, Erik

Year:

2011

Language:

english

File:

PDF, 803 KB

english, 2011

94

Characterization of polymorphisms of an interleukin 1 receptor type 1 gene (IL1RI) promotor region (P2) and their relation to Insulin-Dependent Diabetes Mellitus (IDDM)

Regine Bergholdt, Allan E. Karlsen, Jesper Johannesen, Pernille M. Hansen, Charles A. Dinarello, J ørn Nerup, Flemming Pociot

Journal:

Year:

1995

Language:

english

File:

PDF, 108 KB

english, 1995

95

LINKAGE DISEQUILIBRIUM TESTING OF FOUR INTERLEUKIN-1 GENE-CLUSTER POLYMORPHISMS IN DANISH MULTIPLEX FAMILIES WITH INSULIN-DEPENDENT DIABETES MELLITUS

Ole P Kristiansen, Flemming Pociot, Jesper Johannesen, Regine Bergholdt, Charles A Dinarello, Jørn Nerup, Thomas Mandrup-Poulsen

Journal:

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

96

IDDM2-VNTR-encoded Susceptibility to Type 1 Diabetes: Dominant Protection and Parental Transmission of Alleles of the Insulin Gene-linked Minisatellite Locus

Simon T. Bennett, Amanda J. Wilson, Francesco Cucca, Jørn Nerup, Flemming Pociot, Patricia A. McKinney, Anthony H. Barnett, Stephen C. Bain, John A. Todd

Journal:

Journal of Autoimmunity

Year:

1996

Language:

english

File:

PDF, 280 KB

english, 1996

97

Molecular biology of diabetes I. Autoimmunity and genetics; insulin synthesis and secretion: Edited by B. Draznin and D. LeRoith, The Humana Press; Totowa, NJ, 1994; xv + 404 pages. $89.50. ISBN 0-89603-286-8

Flemming Pociot

Journal:

Year:

1995

Language:

english

File:

PDF, 134 KB

english, 1995

98

Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic β-cell destruction in insulin-dependent diabetes mellitus

Thomas Mandrup-Poulsen, Urs Zumsteg, Jesper Reimers, Flemming Pociot, Lise Mørch, Steffen Helqvist, Charles A. Dinarello, Jørn Nerup

Journal:

Year:

1993

Language:

english

File:

PDF, 793 KB

english, 1993

99

Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3–6 years

J.S. Sorensen, F. Vaziri-Sani, M. Maziarz, K. Kristensen, A. Ellerman, N. Breslow, Å. Lernmark, F. Pociot, C. Brorsson, N.H. Birkebaek

Journal:

Diabetes Research and Clinical Practice

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

100

Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease

Benedicte A. Lie, Marte K. Viken, Hanne E. Akselsen, Siri T. Flåm, Flemming Pociot, Jørn Nerup, Ingrid Kockum, Anne Cambon-Thomsen, Erik Thorsby, Dag E. Undlien

Journal:

Human Immunology

Year:

2007

Language:

english

File:

PDF, 600 KB

english, 2007

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