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101

Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide

Shmueli, Ron B., Ohnaka, Masayuki, Miki, Akiko, Pandey, Niranjan B., Lima e Silva, Raquel, Koskimaki, Jacob E., Kim, Jayoung, Popel, Aleksander S., Campochiaro, Peter A., Green, Jordan J.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

102

Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking

Tan, Wan Hua, Popel, Aleksander S., Mac Gabhann, Feilim

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 3.27 MB

english, 2013

103

A systems biology view of blood vessel growth and remodelling

Logsdon, Elizabeth A., Finley, Stacey D., Popel, Aleksander S., Gabhann, Feilim Mac

Journal:

Journal of Cellular and Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 504 KB

english, 2014

104

Computational systems biology approaches to anti-angiogenic cancer therapeutics

Finley, Stacey D., Chu, Liang-Hui, Popel, Aleksander S.

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 833 KB

english, 2015

105

Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Lee, Esak, Fertig, Elana J., Jin, Kideok, Sukumar, Saraswati, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 4.20 MB

english, 2014

106

Quantitative fluorescent profiling of VEGFRs reveals tumor cell and endothelial cell heterogeneity in breast cancer xenografts

Imoukhuede, Princess. I., Popel, Aleksander S.

Journal:

Cancer Medicine

Year:

2014

Language:

english

File:

PDF, 4.75 MB

english, 2014

107

Lymphatic endothelial cells support tumor growth in breast cancer

Lee, Esak, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 2.53 MB

english, 2014

108

Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells

Schumacher, Kristopher R., Popel, Aleksander S., Anvari, Bahman, Brownell, William E., Spector, Alexander A.

Journal:

Physical Review E

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

109

CALCULATIONS OF OXYGEN TRANSPORT BY RED BLOOD CELLS AND HEMOGLOBIN SOLUTIONS IN CAPILLARIES

Vadapalli, Arjun, Goldman, Daniel, Popel, Aleksander S.

Journal:

Artificial Cells Blood Substitutes and Biotechnology

Year:

2002

Language:

english

File:

PDF, 357 KB

english, 2002

110

Trans-scleral Delivery of Antiangiogenic Proteins

Demetriades, Anna M., Deering, Tye, Liu, Hansheng, Lu, Lili, Gehlbach, Peter, Packer, Jonathan D., Gabhann, Feilim Mac, Popel, Aleksander S., Wei, Lisa L., Campochiaro, Peter A.

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2008

Language:

english

File:

PDF, 146 KB

english, 2008

111

Vascular Smooth Muscle NO Exposure from Intraerythrocytic SNOHb: A Mathematical Model

Chen, Kejing, Pittman, Roland N., Popel, Aleksander S.

Journal:

Antioxidants & Redox Signaling

Year:

2007

Language:

english

File:

PDF, 759 KB

english, 2007

112

Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model

Kim, Eugene, Lee, Esak, Plummer, Charlesa, Gil, Stacy, Popel, Aleksander S., Pathak, Arvind P.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.78 MB

english, 2015

113

Model of nitric oxide diffusion in an arteriole: impact of hemoglobin-based blood substitutes

Kavdia, Mahendra, Tsoukias, Nikolaos M., Popel, Aleksander S.

Journal:

AJP Heart and Circulatory Physiology

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

114

Compartment Model Predicts VEGF Secretion and Investigates the Effects of VEGF Trap in Tumor-Bearing Mice

Finley, Stacey D., Dhar, Manjima, Popel, Aleksander S.

Journal:

Frontiers in Oncology

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

115

Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy

Mac Gabhann, Feilim, Ji, James W., Popel, Aleksander S.

Journal:

PLoS Computational Biology

Year:

2006

Language:

english

File:

PDF, 780 KB

english, 2006

116

Computational fluid dynamics of aggregating red blood cells in postcapillary venules

Chung, Bong, Kim, Sangho, Johnson, Paul C., Popel, Aleksander S.

Journal:

Computer Methods in Biomechanics & Biomedical Engineering

Year:

2009

Language:

english

File:

PDF, 1.96 MB

english, 2009

117

Inhibition of breast cancer growth and metastasis by a biomimetic peptide

Lee, Esak, Lee, Seung Jae, Koskimaki, Jacob E., Han, Zheyi, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 11.15 MB

english, 2014

118

Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancer

Rosca, Elena V., Koskimaki, Jacob E., Pandey, Niranjan B., Wolff, Antonio C., Popel, Aleksander S.

Journal:

Cancer Biology & Therapy

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

119

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling

Stefanini, Marianne O., Wu, Florence T. H., Mac Gabhann, Feilim, Popel, Aleksander S., Pries, Axel R.

Journal:

PLoS Computational Biology

Year:

2009

Language:

english

File:

PDF, 1.51 MB

english, 2009

120

Targeting Neuropilin-1 to Inhibit VEGF Signaling in Cancer: Comparison of Therapeutic Approaches

Gabhann, Feilim Mac, Popel, Aleksander S.

Journal:

PLoS Computational Biology

Year:

2006

Language:

english

File:

PDF, 668 KB

english, 2006

121

Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes

Fertig, Elana J., Lee, Esak, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 638 KB

english, 2015

122

Computational Fluid Dynamic Simulation of Aggregation of Deformable Cells in a Shear Flow

Bagchi, Prosenjit, Johnson, Paul C., Popel, Aleksander S.

Journal:

Journal of Biomechanical Engineering

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

123

Modeling the Mechanics of Tethers Pulled From the Cochlear Outer Hair Cell Membrane

Schumacher, Kristopher R., Popel, Aleksander S., Anvari, Bahman, Brownell, William E., Spector, Alexander A.

Journal:

Journal of Biomechanical Engineering

Year:

2008

Language:

english

File:

PDF, 726 KB

english, 2008

124

Multiscale Modeling in the Clinic: Drug Design and Development

Clancy, Colleen E., An, Gary, Cannon, William R., Liu, Yaling, May, Elebeoba E., Ortoleva, Peter, Popel, Aleksander S., Sluka, James P., Su, Jing, Vicini, Paolo, Zhou, Xiaobo, Eckmann, David M.

Journal:

Annals of Biomedical Engineering

Year:

2016

Language:

english

File:

PDF, 3.14 MB

english, 2016

125

Effect of aggregation and shear rate on the dispersion of red blood cells flowing in venules

Bishop, Jeffrey J., Popel, Aleksander S., Intaglietta, Marcos, Johnson, Paul C.

Journal:

AJP Heart and Circulatory Physiology

Year:

2002

Language:

english

File:

PDF, 1.04 MB

english, 2002

126

PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease

Chu, Liang-Hui, Vijay, Chaitanya G., Annex, Brian H., Bader, Joel S., Popel, Aleksander S.

Journal:

Physiological Genomics

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

127

Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth

Rosca, Elena Victoria, Lal, Bachchu, Koskimaki, Jacob E., Popel, Aleksander S., Laterra, John

Journal:

Anti-Cancer Drugs

Year:

2012

Language:

english

File:

PDF, 547 KB

english, 2012

128

A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse

Chu, Liang-Hui, Ganta, Vijay Chaitanya, Choi, Min H., Chen, George, Finley, Stacey D., Annex, Brian H., Popel, Aleksander S.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.81 MB

english, 2016

129

Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis

Norton, Kerri-Ann, Popel, Aleksander S.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

130

Gene delivery nanoparticles to modulate angiogenesis

Kim, Jayoung, Mirando, Adam C., Popel, Aleksander S., Green, Jordan J.

Journal:

Advanced Drug Delivery Reviews

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

131

The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts

Dore-Savard, Louis, Lee, Esak, Kakkad, Samata, Popel, Aleksander S., Bhujwalla, Zaver M.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

132

Tyrosine kinase blocking collagen IV–derived peptide suppresses ocular neovascularization and vascular leakage

Lima e Silva, Raquel, Kanan, Yogita, Mirando, Adam C., Kim, Jayoung, Shmueli, Ron B., Lorenc, Valeria E., Fortmann, Seth D., Sciamanna, Jason, Pandey, Niranjan B., Green, Jordan J., Popel, Aleksander

Journal:

Science Translational Medicine

Year:

2017

Language:

english

File:

PDF, 3.36 MB

english, 2017

133

Nanostructure, Effective Properties, and Deformation Pattern of the Cochlear Outer Hair Cell Cytoskeleton

Spector, Alexander A., Ameen, Mohammed, Charalambides, Panos G., Popel, Aleksander S.

Journal:

Journal of Biomechanical Engineering

Year:

2002

Language:

english

File:

PDF, 400 KB

english, 2002

134

Theoretical analysis of effects of blood substitute affinity and cooperativity on organ oxygen transport

Kavdia, Mahendra, Pittman, Roland N., Popel, Aleksander S.

Journal:

Journal of Applied Physiology

Year:

2002

Language:

english

File:

PDF, 321 KB

english, 2002

135

A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition

Gong, Chang, Milberg, Oleg, Wang, Bing, Vicini, Paolo, Narwal, Rajesh, Roskos, Lorin, Popel, Aleksander S.

Journal:

Journal of The Royal Society Interface

Year:

2017

Language:

english

File:

PDF, 4.11 MB

english, 2017

136

Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells

Bressler, Eric M., Kim, Jayoung, Shmueli, Ron B., Mirando, Adam C., Bazzazi, Hojjat, Lee, Esak, Popel, Aleksander S., Pandey, Niranjan B., Green, Jordan J.

Journal:

Journal of Biomedical Materials Research Part A

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

137

Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis

Gkontra, Polyxeni, Norton, Kerri-Ann, Żak, Magdalena M., Clemente, Cristina, Agüero, Jaume, Ibáñez, Borja, Santos, Andrés, Popel, Aleksander S., Arroyo, Alicia G.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 9.64 MB

english, 2018

138

Human expression patterns: qualitative and quantitative analysis of thrombospondin-1 under physiological and pathological conditions

Zhao, Chen, Isenberg, Jeffrey S., Popel, Aleksander S.

Journal:

Journal of Cellular and Molecular Medicine

Year:

2018

Language:

english

File:

PDF, 362 KB

english, 2018

139

An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

Norton, Kerri-Ann, Wallace, Travis, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

BMC Systems Biology

Year:

2017

Language:

english

File:

PDF, 2.25 MB

english, 2017

140

Modeling triple-negative breast cancer heterogeneity: effects of stromal macrophages, fibroblasts and tumor vasculature

Norton, Kerri-Ann, Jin, Kideok, Popel, Aleksander S.

Journal:

Journal of Theoretical Biology

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

141

A Model of Nitric Oxide Capillary Exchange

TSOUKIAS, NIKOLAOS M., POPEL, ALEKSANDER S.

Journal:

Microcirculation

Year:

2003

Language:

english

File:

PDF, 698 KB

english, 2003

142

Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer

Zhao, Chen, Popel, Aleksander S., Saucerman, Jeffrey J.

Journal:

PLoS Computational Biology

Year:

2015

Language:

english

File:

PDF, 2.34 MB

english, 2015

143

Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model

Zhao, Chen, Isenberg, Jeffrey S., Popel, Aleksander S., Saucerman, Jeffrey J.

Journal:

PLoS Computational Biology

Year:

2017

Language:

english

File:

PDF, 3.24 MB

english, 2017

144

A Biomimetic Collagen Derived Peptide Exhibits Anti-Angiogenic Activity in Triple Negative Breast Cancer

Rosca, Elena V., Penet, Marie-France, Mori, Noriko, Koskimaki, Jacob E., Lee, Esak, Pandey, Niranjan B., Bhujwalla, Zaver M., Popel, Aleksander S., Tan, Ming

Journal:

Year:

2014

Language:

english

File:

PDF, 844 KB

english, 2014

145

Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells

Bazzazi, Hojjat, Popel, Aleksander S., Diamond, Scott L

Journal:

PLoS Computational Biology

Year:

2017

Language:

english

File:

PDF, 2.16 MB

english, 2017

146

A Compartment Model of VEGF Distribution in Humans in the Presence of Soluble VEGF Receptor-1 Acting as a Ligand Trap

Wu, Florence T. H., Stefanini, Marianne O., Mac Gabhann, Feilim, Popel, Aleksander S., Lucia, Alejandro

Journal:

Year:

2009

Language:

english

File:

PDF, 2.20 MB

english, 2009

147

Quantifying the Proteolytic Release of Extracellular Matrix-Sequestered VEGF with a Computational Model

Vempati, Prakash, Mac Gabhann, Feilim, Popel, Aleksander S., Federici, Massimo

Journal:

Year:

2010

Language:

english

File:

PDF, 1.74 MB

english, 2010

148

Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

Rivera, Corban G., Mellberg, Sofie, Claesson-Welsh, Lena, Bader, Joel S., Popel, Aleksander S., Deb, Sumitra

Journal:

Year:

2011

Language:

english

File:

PDF, 655 KB

english, 2011

149

[ASME ASME 2009 Summer Bioengineering Conference - Lake Tahoe, California, USA (Wednesday 17 June 2009)] ASME 2009 Summer Bioengineering Conference, Parts A and B - Computational Analysis of the Tether Pulling Experiment to Probe Cellular Membranes

Schumacher, Kristopher, Popel, Aleksander, Anvari, Bahman, Brownell, William, Spector, Alexander

Year:

2009

Language:

english

File:

PDF, 167 KB

english, 2009

150

Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Jin, Kideok, Pandey, Niranjan B., Popel, Aleksander S.

Journal:

Breast Cancer Research

Year:

2018

Language:

english

File:

PDF, 2.93 MB

english, 2018