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51

Toward a new paradigm for the efficient in vitro - in vivo extrapolation of metabolic clearance in humans from hepatocyte data

Poulin, Patrick, Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 382 KB

english, 2013

52

Methodology developed to make the Quebec indoor radon potential map

Drolet, Jean-Philippe, Martel, Richard, Poulin, Patrick, Dessau, Jean-Claude

Journal:

Science of The Total Environment

Year:

2014

Language:

english

File:

PDF, 2.09 MB

english, 2014

53

Recognition of Dizygotic and Monozygotic Twin Lambs by Ewes

Alain Romeyer, Richard H. Porter, Pascal Poindron, Pierre Orgeur, Patrick Chesné and Nati Poulin

Journal:

Year:

1993

Language:

english

File:

PDF, 494 KB

english, 1993

54

Effect of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase, on polyamine metabolism in mammalian cells

Pegg, Anthony E., Wechter, Rita, Poulin, Richard, Woster, Patrick M., Coward, James K.

Journal:

Year:

1989

Language:

english

File:

PDF, 995 KB

english, 1989

55

[IEEE 2011 24th IEEE Canadian Conference on Electrical and Computer Engineering (CCECE) - Niagara Falls, ON, Canada (2011.05.8-2011.05.11)] 2011 24th Canadian Conference on Electrical and Computer Engineering(CCECE) - Artificial neural network acceleration on FPGA using custom instruction

Santos, Patrick, Ouellet-Poulin, David, Shapiro, Daniel, Bolic, Miodrag

Year:

2011

Language:

english

File:

PDF, 161 KB

english, 2011

56

[IEEE 2010 IEEE Topical Meeting on Microwave Photonics (MWP 2010) - Montreal, QC, Canada (2010.10.5-2010.10.9)] 2010 IEEE International Topical Meeting on Microwave Photonics - Laser synthesizer of the ALMA telescope: Design and performance

Ayotte, Simon, Babin, Andre, Poulin, Patrick, Poulin, Michel, Jeanneau, Amelie, Picard, Marie-Josee, Poulin, Daniel, Davidson, Charles-Andre, Aube, Maryse, Alexandre, Isabelle, Costin, Francois, Pelle

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

57

Enkephalin knockdown in the central amygdala nucleus reduces unconditioned fear and anxiety

Poulin, Jean-François, Bérubé, Patrick, Laforest, Sylvie, Drolet, Guy

Journal:

European Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 3.85 MB

english, 2013

58

Evaluation of Continuous Positive Airway Pressure Therapy on Renin–Angiotensin System Activity in Obstructive Sleep Apnea

Nicholl, David D. M., Hanly, Patrick J., Poulin, Marc J., Handley, George B., Hemmelgarn, Brenda R., Sola, Darlene Y., Ahmed, Sofia B.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 701 KB

english, 2014

59

Improved structure and properties of single-wall carbon nanotube spun fibers

Vigolo, Brigitte, Poulin, Philippe, Lucas, Marcel, Launois, Pascale, Bernier, Patrick

Journal:

Applied Physics Letters

Year:

2002

Language:

english

File:

PDF, 423 KB

english, 2002

60

Effects of Acute Intermittent Hypoxia on Working Memory in Young Healthy Adults

Champod, Anne Sophie, Eskes, Gail A., Foster, Glen E., Hanly, Patrick J., Pialoux, Vincent, Beaudin, Andrew E., Poulin, Marc J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 688 KB

english, 2013

61

Hepatocyte composition-based model as a mechanistic tool for predicting the cell suspension: Aqueous phase partition coefficient of drugs in in vitro metabolic studies

Poulin, Patrick, Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 298 KB

english, 2013

62

Enkephalin Knockdown in the Basolateral Amygdala Reproduces Vulnerable Anxiety-Like Responses to Chronic Unpredictable Stress

Bérubé, Patrick, Poulin, Jean-François, Laforest, Sylvie, Drolet, Guy

Journal:

Neuropsychopharmacology

Year:

2014

Language:

english

File:

PDF, 766 KB

english, 2014

63

Effects of Exposure to Intermittent Hypoxia on Oxidative Stress and Acute Hypoxic Ventilatory Response in Humans

Pialoux, Vincent, Hanly, Patrick J., Foster, Glen E., Brugniaux, Julien V., Beaudin, Andrew E., Hartmann, Sara E., Pun, Matiram, Duggan, Cailean T., Poulin, Marc J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 144 KB

english, 2009

64

Prediction of Drug Distribution in Subcutaneous Xenografts of Human Tumor Cell Lines and Healthy Tissues in Mouse: Application of the Tissue Composition-Based Model to Antineoplastic Drugs

Poulin, Patrick, Chen, Yung-Hsiang, Ding, Xiao, Gould, Stephen E., Hop, Cornelis Eca, Messick, Kirsten, Oeh, Jason, Liederer, Bianca M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 325 KB

english, 2015

65

Molecular Structure-Based Prediction of the Partition Coefficients of Organic Chemicals for Physiological Pharmacokinetic Models

Poulin, Patrick, Krishnan, Kannan

Journal:

Toxicology Mechanisms and Methods

Year:

1996

Language:

english

File:

PDF, 1.29 MB

english, 1996

66

Findings from an Extended Case Management U.S. Refugee Resettlement Program

Shaw, Stacey A., Poulin, Patrick

Journal:

Journal of International Migration and Integration

Year:

2015

Language:

english

File:

PDF, 306 KB

english, 2015

67

Randomized prospective trial comparing two supraglottic airway devices: i-gel™ and LMA-Supreme™ in paralyzed patients

Joly, Nikola, Poulin, Louis-Pierre, Tanoubi, Issam, Drolet, Pierre, Donati, François, St-Pierre, Patrick

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

2014

Language:

english

File:

PDF, 409 KB

english, 2014

68

Molecular Structure-Based Prediction of the Toxicokinetics of Inhaled Vapors in Humans

Krishnan, Patrick Poulin, Kannan

Journal:

International Journal of Toxicology

Year:

1999

Language:

english

File:

PDF, 274 KB

english, 1999

69

MOLECULAR STRUCTURE-BASED PREDICTION OF HUMAN ABDOMINAL SKIN PERMEABILITY COEFFICIENTS FOR SEVERAL ORGANIC COMPOUNDS

Poulin, Patrick, Krishnan, Kannan

Journal:

Journal of Toxicology and Environmental Health

Year:

2001

Language:

english

File:

PDF, 215 KB

english, 2001

70

Nocturnal Hypoxemia Severity Determines Renin-Angiotensin System Activity in Obstructive Sleep Apnea

Zalucky, Ann A, Nicholl, David D.M., Hanly, Patrick J, Poulin, Marc J, Turin, Tanvir C, Walji, Shahebina, Handley, George B, Raneri, Jill K, Sola, Darlene Y, Ahmed, Sofia B.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2015

Language:

english

File:

PDF, 548 KB

english, 2015

71

[ACM Press the 13th international symposium - Los Angeles, California (2008.08.09-2008.08.10)] Proceedings of the 13th international symposium on 3D web technology - Web3D '08 - Efficient streaming of 3D scenes with complex geometry and complex lighting

Pacanowski, Romain, Raynaud, Mickaël, Granier, Xavier, Reuter, Patrick, Schlick, Christophe, Poulin, Pierre

Year:

2008

Language:

english

File:

PDF, 5.46 MB

english, 2008

72

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A70. SLEEP DISORDERED BREATHING: CARDIOVASCULAR AND METABOLIC ASPECTS - Obstructive Sleep Apnea And The Vascular Renin Angiotensin System In Humans

Nicholl, David D.M., Hanly, Patrick, Handley, George, Hemmelgarn, Brenda, Poulin, Marc, Sola, Darlene, Ahmed, Sofia B.

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

73

Effects of Continuous Positive Airway Pressure on Cerebral Vascular Response to Hypoxia in Patients with Obstructive Sleep Apnea

Foster, Glen E., Hanly, Patrick J., Ostrowski, Michele, Poulin, Marc J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 511 KB

english, 2007

74

Recognition of Dizygotic and Monozygotic Twin Lambs By Ewes

Romeyer, Alain, Porter, Richard H., Poulin, Nati, Orgeur, Pierre, Poindron, Pascal, Chesne, Patrick

Journal:

Year:

1993

Language:

english

File:

PDF, 2.55 MB

english, 1993

75

Drug Distribution to Human Tissues: Prediction and Examination of the Basic Assumption in In Vivo Pharmacokinetics-Pharmacodynamics (PK/PD) Research

Poulin, Patrick

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 233 KB

english, 2015

76

Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36

Poulin, Myles B., Schneck, Jessica L., Matico, Rosalie E., McDevitt, Patrick J., Huddleston, Michael J., Hou, Wangfang, Johnson, Neil W., Thrall, Sara H., Meek, Thomas D., Schramm, Vern L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1019 KB

english, 2016

77

A Paradigm Shift in Pharmacokinetic–Pharmacodynamic (PKPD) Modeling: Rule of Thumb for Estimating Free Drug Level in Tissue Compared with Plasma to Guide Drug Design

Poulin, Patrick

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 285 KB

english, 2015

78

The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro-to-In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research

Poulin, Patrick, Burczynski, Frank J., Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

79

Correlation of Tissue-Plasma Partition Coefficients Between Normal Tissues and Subcutaneous Xenografts of Human Tumor Cell Lines in Mouse as a Prediction Tool of Drug Penetration in Tumors

Poulin, Patrick, Hop, Cornelis Eca, Salphati, Laurent, Liederer, Bianca M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

80

“Nucleosome binding alters the substrate bonding environment of Histone H3 Lysine 36 Methyltransferase NSD2”

Poulin, Myles B., Schneck, Jessica L, Matico, Rosalie E., Hou, Wangfang, McDevitt, Patrick J., Holbert, Marc, Schramm, Vern L.

Journal:

Journal of the American Chemical Society

Year:

2016

Language:

english

File:

PDF, 451 KB

english, 2016

81

Dispersions and fibers of carbon nanotubes

Vigolo, Brigitte, Pénicaud, Alain, Coulon, Claude, Sauder, Cédric, Pailler, René, Journet, Catherine, Bernier, Patrick, Poulin, Philippe

Journal:

MRS Proceedings

Year:

2000

Language:

english

File:

PDF, 4.87 MB

english, 2000

82

Fibers of Carbon Nanotubes

Vigolo, Brigitte, Launois, Pascale, Lucas, Marcel, Badaire, Stéphane, Bernier, Patrick, Poulin, Philippe

Journal:

MRS Proceedings

Year:

2001

Language:

english

File:

PDF, 1.19 MB

english, 2001

83

Albumin and Uptake of Drugs in Cells: Additional Validation Exercises of a Recently Published Equation that Quantifies the Albumin-Facilitated Uptake Mechanism(s) in Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling Research

Poulin, Patrick, Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 154 KB

english, 2015

84

Minimally Invasive Adrenalectomy for Pheochromocytoma During Pregnancy

Pace, David E., Chiasson, Patrick M., Schlachta, Christopher M., Mamazza, Joseph, Cadeddu, Margherita O., Poulin, Eric C.

Journal:

Surgical Laparoscopy Endoscopy & Percutaneous Techniques

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

85

SPIE Proceedings [SPIE IS&T/SPIE Electronic Imaging - San Jose, California (Sunday 17 January 2010)] Computational Imaging VIII - Human pose tracking from monocular video by traversing an image motion mapped body pose manifold

Basu, Saurav, Bouman, Charles A., Pollak, Ilya, Poulin, Joshua, Acton, Scott T., Wolfe, Patrick J.

Year:

2010

Language:

english

File:

PDF, 4.17 MB

english, 2010

86

Carbon Nanotube Fiber Microelectrodes: Design, Characterization, and Optimization

Viry, Lucie, Derré, Alain, Garrigue, Patrick, Sojic, Neso, Poulin, Philippe, Kuhn, Alexander

Journal:

Journal of Nanoscience and Nanotechnology

Year:

2007

Language:

english

File:

PDF, 3.66 MB

english, 2007

87

SPIE Proceedings [SPIE Bruges, Belgium - Deadline Past - Bruges, Belgium (Monday 23 May 2005)] 17th International Conference on Optical Fibre Sensors - Combined fiber optic sensor for colour and refractive index (CI) monitoring

Trudeau, Jean-Marie, Paradis, Patrick, Pare, Claude, Meneghini, Chiara, Jacob-Poulin, Anne-Claire, Cournoyer, Alain, Savard, Eric, Doyon, Gilles

Year:

2005

Language:

english

File:

PDF, 295 KB

english, 2005

88

Effects of continuous positive airway pressure and isocapnic-hypoxia on cerebral autoregulation in patients with obstructive sleep apnea

Waltz, Xavier, Beaudin, Andrew E., Hanly, Patrick J., Mitsis, Georgios D., Poulin, Marc J.

Journal:

The Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

89

Evidence of association between sleep quality and APOE ε4 in healthy older adults

Drogos, Lauren L., Gill, Stephanie J., Tyndall, Amanda V., Raneri, Jill K., Parboosingh, Jillian S., Naef, Aileen, Guild, Kyle D., Eskes, Gail, Hanly, Patrick J., Poulin, Marc J.

Journal:

Year:

2016

Language:

english

File:

PDF, 269 KB

english, 2016

90

Predictions of bisphenol A hepatic clearance in the Isolated Perfused Rat Liver (IPRL): impact of albumin binding and of co-administration with naproxen.

Bounakta, Sara, Bteich, Michel, Mantha, Marc, Poulin, Patrick, Haddad, Sami

Journal:

Year:

2017

Language:

english

File:

PDF, 675 KB

english, 2017

91

Impact of obstructive sleep apnoea and intermittent hypoxia on cardiovascular and cerebrovascular regulation

Beaudin, Andrew E, Waltz, Xavier, Hanly, Patrick J, Poulin, Marc J

Journal:

Experimental Physiology

Year:

2017

Language:

english

File:

PDF, 1.97 MB

english, 2017

92

Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults

Khalyfa, Abdelnaby, Zhang, Chunling, Khalyfa, Ahamed A., Foster, Glen E., Beaudin, Andrew E., Andrade, Jorge, Hanly, Patrick J., Poulin, Marc J., Gozal, David

Journal:

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

93

Towards Organisational Control of Network Enterprise

Poulin, Diane, Vincent, Lucien, Burlat, Patrick

Journal:

IFAC Proceedings Volumes

Year:

2000

Language:

english

File:

PDF, 975 KB

english, 2000

94

Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1

Trottier, Alexandre, Maltais, René, Ayan, Diana, Barbeau, Xavier, Roy, Jenny, Perreault, Martin, Poulin, Richard, Lagüe, Patrick, Poirier, Donald

Journal:

Biochemical Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

95

Supplemental Analysis of the Prediction of Hepatic Clearance of Binary Mixtures of Bisphenol A and Naproxen Determined in an Isolated Perfused Rat Liver Model to Promote the Understanding of Potential Albumin-Facilitated Hepatic Uptake Mechanism

Poulin, Patrick, Bteich, Michel, Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 281 KB

english, 2017

96

Extrapolation Of The Hepatic Clearance Of Drugs In The Absence Of Albumin In Vitro To That In The Presence Of Albumin In Vivo: Comparative Assessement Of Two Extrapolation Models Based On The Albumin-Mediated Hepatic Uptake Theory And Limitations And Mechanistic Insights

Poulin, Patrick, Haddad, Sami

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 431 KB

english, 2018

97

Improving Prediction Of Metabolic Clearance Using Quantitative Extrapolation Of Results Obtained From Human Hepatic Mpcc Model And By Considering The Impact Of Albumin Binding

Da-silva, Franck, Boulenc, Xavier, Vermet, Hélène, Compigne, Pauline, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Klieber, Sylvie, Poulin, Patrick

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

98

: application to the Higgs portal model and evaporating black holes

Stöcker, Patrick, Krämer, Michael, Lesgourgues, Julien, Poulin, Vivian

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2018

Language:

english

File:

PDF, 5.45 MB

english, 2018

99

Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia

Khalyfa, Abdelnaby, Youssefnia, Nina, Foster, Glen E., Beaudin, Andrew E., Qiao, Zhuanghong, Pialoux, Vincent, Pun, Matiram, Hanly, Patrick J., Kheirandish-Gozal, Leila, Poulin, Marc J., Gozal, David

Journal:

Frontiers in Neurology

Year:

2017

Language:

english

File:

PDF, 2.17 MB

english, 2017

100

Effect of Acute, Subacute, and Repeated Exposure to High Altitude (5050 m) on Psychomotor Vigilance

Pun, Matiram, Hartmann, Sara E., Furian, Michael, Dyck, Adrienna M., Muralt, Lara, Lichtblau, Mona, Bader, Patrick R., Rawling, Jean M., Ulrich, Silvia, Bloch, Konrad E., Poulin, Marc J.

Journal:

Frontiers in Physiology

Year:

2018

Language:

english

File:

PDF, 3.01 MB

english, 2018

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