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51

Investigation on constitutive IKK activity in the axon initial segment

Robert Schwamborn, Christian Schultz, Thomas Deller, Hans-Georg König, Jochen Prehn

Journal:

BMC Neuroscience

Year:

2007

Language:

english

File:

PDF, 133 KB

english, 2007

52

Role of 5′-Adenosine Monophosphate-Activated Protein Kinase in Cell Survival and Death Responses in Neurons

Weisová, Petronela, Dávila, David, Tuffy, Liam P., Ward, Manus W., Concannon, Caoimhín G., Prehn, Jochen H.M.

Journal:

Antioxidants & Redox Signaling

Year:

2011

Language:

english

File:

PDF, 700 KB

english, 2011

53

Effects of serotonergic drugs in experimental brain ischemia: evidence for a protective role of serotonin in cerebral ischemia

Jochen H.M. Prehn, Matthias Welsch, Cord Backhauß, Jörg Nuglisch, Franz Ausmeier, Chourouk Karkoutly, Josef Krieglstein

Journal:

Year:

1993

Language:

english

File:

PDF, 1.16 MB

english, 1993

54

Neuroprotective properties of 5-HT1A receptor agonists En rodent models of focal and global cerebral ischemia

Jochen H.M. Prehn, Cord Backhauβ, Chourouk Karkoutly, Jörg Nuglisch, Barbara Peruche, Christine Roβberg, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.35 MB

english, 1991

55

Marked diversity in the action of growth factors on N-methyl-d-rmaspartate-induced neuronal degeneration

Jochen H.M. Prehn

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1022 KB

english, 1996

56

Opposite effects of TGF-β1 on rapidly- and slowly-triggered excitotoxic injury

Jochen H.M. Prehn, Richard J. Miller

Journal:

Neuropharmacology

Year:

1996

Language:

english

File:

PDF, 1006 KB

english, 1996

57

Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons

Christian Schultz, Hans-Georg König, Domenico Del Turco, Chrisoula Politi, Gunter P. Eckert, Estifanos Ghebremedhin, Jochen H.M. Prehn, Donat Kögel, Thomas Deller

Journal:

Molecular and Cellular Neuroscience

Year:

2006

Language:

english

File:

PDF, 1.15 MB

english, 2006

58

Effects of transient focal cerebral ischemia in mice deficient in puma

Katsura Kuroki, Isabelle Virard, Caoimhin G. Concannon, Tobias Engel, Ina Woods, Waro Taki, Nikolaus Plesnila, David C. Henshall, Jochen H.M. Prehn

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

59

The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis

Donat Kögel, Caoimhín G. Concannon, Thorsten Müller, Hildegard König, Caroline Bonner, Simone Poeschel, Steffi Chang, Rupert Egensperger, Jochen H.M. Prehn

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

60

Reduced sleep-associated consolidation of declarative memory in attention-deficit/hyperactivity disorder

Alexander Prehn-Kristensen, Robert Göder, Jochen Fischer, Ines Wilhelm, Mareen Seeck-Hirschner, Josef Aldenhoff, Lioba Baving

Journal:

Year:

2011

Language:

english

File:

PDF, 243 KB

english, 2011

61

P1-174 The role of the APP intracellular domain (AICD) in gene expression: implications for Alzheimer's disease

Rupert Egensperger, Thorsten Mueller, Donat Kögel, Jochen H. Prehn

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

62

P2-032: Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

Rupert Egensperger, Thorsten Mueller, Caoimhin G. Concannon, Manus W. Ward, Donat Kogel, Jochen H.M. Prehn

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

63

Early decrease in mitochondrial potential in β-amyloid neurotoxicity: Effect of the neuroprotectant transforming growth factor-β

Jochen H.M. Prehn, Vytautas P. Bindokas, Josef Krieglstein, Richard J. Miller

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 146 KB

english, 1995

64

Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward

Siobhan Bacon, Ma Peyh Kyithar, Jasmin Schmid, Syed R Rizvi, Caroline Bonner, Rolf Graf, Jochen HM Prehn, Maria M Byrne

Journal:

BMC Endocrine Disorders

Year:

2012

Language:

english

File:

PDF, 200 KB

english, 2012

65

Systems modelling methodology for the analysis of apoptosis signal transduction and cell death decisions

Rehm, Markus, Prehn, Jochen H.M.

Journal:

Year:

2013

Language:

english

File:

PDF, 703 KB

english, 2013

66

The indirect activation model of mitochondrial outer membrane permeabilisation (MOMP) initiation requires a trade-off between robustness in the absence of and sensitivity in the presence of stress

Lindner, Andreas U., Prehn, Jochen H. M., Huber, Heinrich J.

Journal:

Molecular BioSystems

Year:

2013

Language:

english

File:

PDF, 4.21 MB

english, 2013

67

Angiogenin induces modifications in the astrocyte secretome: Relevance to amyotrophic lateral sclerosis

Skorupa, Alexandra, Urbach, Serge, Vigy, Oana, King, Matthew A., Chaumont-Dubel, Séverine, Prehn, Jochen H.M., Marin, Philippe

Journal:

Journal of Proteomics

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

68

Harnessing system models of cell death signalling for cytotoxic chemotherapy: towards personalised medicine approaches?

Huber, Heinrich J., McKiernan, Ross G., Prehn, Jochen H. M.

Journal:

Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 577 KB

english, 2014

69

The Frequencies and Clinical Implications of Mutations in 33 Kinase-Related Genes in Locally Advanced Rectal Cancer: A Pilot Study

Abdul-Jalil, Khairun I., Sheehan, Katherine M., Toomey, Sinead, Schmid, Jasmin, Prehn, Jochen, O’Grady, Anthony, Cummins, Robert, O’Neill, Brian, McNamara, Deborah A., Deasy, Joseph, Breathnach, Oscar

Journal:

Annals of Surgical Oncology

Year:

2014

Language:

english

File:

PDF, 286 KB

english, 2014

70

Increased Expression of MicroRNA-29a in ALS Mice: Functional Analysis of Its Inhibition

Nolan, Katie, Mitchem, Mollie R., Jimenez-Mateos, Eva M., Henshall, David C., Concannon, Caoimhín G., Prehn, Jochen H. M.

Journal:

Journal of Molecular Neuroscience

Year:

2014

Language:

english

File:

PDF, 3.22 MB

english, 2014

71

Novel Benzylidene-9(10 H )-anthracenones as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization

Prinz, Helge, Ishii, Yukihito, Hirano, Takeo, Stoiber, Thomas, Camacho Gomez, Juan A., Schmidt, Peter, Düssmann, Heiko, Burger, Angelika M., Prehn, Jochen H. M., Günther, Eckhard G., Unger, Eberhard,

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 294 KB

english, 2003

72

Molecular imaging in the development of a novel treatment paradigm for glioblastoma (GBM): an integrated multidisciplinary commentary

Jarzabek, Monika A., Sweeney, Kieron J., Evans, Rhys L., Jacobs, Andreas H., Stupp, Roger, O’Brien, Donncha, Berger, Mitchel S., Prehn, Jochen H.M., Byrne, Annette T.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 5.28 MB

english, 2013

73

Unsupervised mitochondria segmentation using recursive spectral clustering and adaptive similarity models

Dietlmeier, Julia, Ghita, Ovidiu, Duessmann, Heiko, Prehn, Jochen H.M., Whelan, Paul F.

Journal:

Journal of Structural Biology

Year:

2013

Language:

english

File:

PDF, 3.30 MB

english, 2013

74

932 Targeting the 19S Proteasomal Subunit, Rpt4, in Colon Cancer Cells Induces Cell Death and Reduces Cellular Proliferation In Vitro and In Vivo

Boland, Karen, Concannon, Caoimhin, McCawley, Niamh, Kay, Elaine W., McNamara, Deborah, Murray, Frank E., Ramtoola, Zebunnissa, Byrne, Annette, Prehn, Jochen H.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 237 KB

english, 2013

75

BH3 Mimetics Reactivate Autophagic Cell Death in Anoxia-Resistant Malignant Glioma Cells

Hetschko, Holger, Voss, Valerie, Senft, Christian, Seifert, Volker, Prehn, Jochen H.M., Kögel, Donat

Journal:

Year:

2008

Language:

english

File:

PDF, 859 KB

english, 2008

76

Are NMDA or AMPA/kainate receptor antagonists more efficacious in the delayed treatment of excitotoxic neuronal injury?

Prehn, Jochen H.M., Lippert, Klaus, Krieglstein, Josef

Journal:

European Journal of Pharmacology: Environmental Toxicology and Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.02 MB

english, 1995

77

T1161 BH3 Mimetics Can Overcome Resistance to Chemotherapy in Colorectal Cancer

Cannon, Mary D., Concannon, Caoimhin, Hector, Suzanne, Murray, Frank E., Prehn, Jochen H.

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 171 KB

english, 2010

78

W1932 The BCL-2 Family of Proteins As a New Therapeutic Target for the Treatment of Colorectal Cancer

Cannon, Mary D., Concannon, Caoimhin, Murray, Frank E., Prehn, Jochen H.

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

79

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

König, Hans-Georg, Coughlan, Karen S., Kinsella, Sinéad, Breen, Bridget A., Prehn, Jochen H.M.

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

80

The metabolic response to excitotoxicity – lessons from single-cell imaging

Connolly, Niamh M. C., Prehn, Jochen H. M.

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

81

A structured approach to the study of metabolic control principles in intact and impaired mitochondria

Huber, Heinrich J., Connolly, Niamh M. C., Dussmann, Heiko, Prehn, Jochen H. M.

Journal:

Molecular BioSystems

Year:

2012

Language:

english

File:

PDF, 4.20 MB

english, 2012

82

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1

Anilkumar, Ujval, Weisová, Petronela, Düssmann, Heiko, Concannon, Caoimhín G., König, Hans-Georg, Prehn, Jochen H. M.

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

83

Regulation of Neuronal Bc12 Protein Expression and Calcium Homeostasis by Transforming Growth Factor Type β Confers Wide-Ranging Protection on Rat Hippocampal Neurons

Jochen H. M. Prehn, Vytautas P. Bindokas, Charles J. Marcuccilli, Stanislaw Krajewski, John C. Reed and Richard J. Miller

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.07 MB

english, 1994

84

Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles

Dmitriev, Ruslan I., Borisov, Sergey M., Kondrashina, Alina V., Pakan, Janelle M. P., Anilkumar, Ujval, Prehn, Jochen H. M., Zhdanov, Alexander V., McDermott, Kieran W., Klimant, Ingo, Papkovsky, Dmit

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 4.52 MB

english, 2015

85

“Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1G93A mice

Coughlan, Karen S., Mitchem, Mollie R., Hogg, Marion C., Prehn, Jochen H.M.

Journal:

Neurobiology of Aging

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

86

Protein Macroarray Profiling of Serum Autoantibodies in Pseudoexfoliation Glaucoma

Dervan, Edward W., Chen, Hong, Ho, Su Ling, Brummel, Nikola, Schmid, Jasmin, Toomey, David, Haralambova, Margarita, Gould, Edith, Wallace, Deborah M., Prehn, Jochen H. M., O'Brien, Colm J., Murphy, De

Journal:

Investigative Ophthalmology & Visual Science

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

87

Versatile Conjugated Polymer Nanoparticles for High-Resolution O 2 Imaging in Cells and 3D Tissue Models

Dmitriev, Ruslan I., Borisov, Sergey M., Düssmann, Heiko, Sun, Shiwen, Müller, Bernhard J., Prehn, Jochen, Baklaushev, Vladimir P., Klimant, Ingo, Papkovsky, Dmitri B.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

88

Validation of an imageable surgical resection animal model of Glioblastoma (GBM)

Sweeney, Kieron J., Jarzabek, Monika A., Dicker, Patrick, O’Brien, Donncha F., Callanan, John J., Byrne, Annette T., Prehn, Jochen H.M.

Journal:

Journal of Neuroscience Methods

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

89

Endonuclease-G and the pathways to dopaminergic neurodegeneration: a question of location?

Hogg, Marion C, Prehn, Jochen H M

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

90

Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation

Ionescu, Crina-Maria, Svobodová Vařeková, Radka, Prehn, Jochen H. M., Huber, Heinrich J., Koča, Jaroslav, Briggs, James M.

Journal:

PLoS Computational Biology

Year:

2012

Language:

english

File:

PDF, 757 KB

english, 2012

91

Gene Expression during ER Stress-Induced Apoptosis in Neurons: Induction of the BH3-Only Protein Bbc3/PUMA and Activation of the Mitochondrial Apoptosis Pathway

Claus Reimertz, Donat Kögel, Abdelhaq Rami, Thomas Chittenden and Jochen H. M. Prehn

Journal:

The Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 3.27 MB

english, 2003

92

Real-Time Single Cell Analysis of Smac/DIABLO Release during Apoptosis

Markus Rehm, Heiko Düßmann and Jochen H. M. Prehn

Journal:

The Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 3.29 MB

english, 2003

93

Endoplasmic Reticulum Stress and Apoptosis Signaling in Human Temporal Lobe Epilepsy

Yamamoto, Akitaka, Murphy, Niamh, Schindler, Clara K., So, Norman K., Stohr, Sabine, Taki, Waro, Prehn, Jochen H. M., Henshall, David C.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

94

Caspase 6 has a protective role in SOD1G93A transgenic mice

Hogg, Marion C., Mitchem, Mollie R., König, Hans-Georg, Prehn, Jochen H.M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

95

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer

Boland, Karen, Flanagan, Lorna, McCawley, Niamh, Pabari, Ritesh, Kay, Elaine W., McNamara, Deborah A., Murray, Frank, Byrne, Annette T., Ramtoola, Zebunnissa, Concannon, Caoimhín G., Prehn, Jochen H.M

Journal:

European Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.00 MB

english, 2016

96

Colorectal tumour simulation using agent based modelling and high performance computing

Kang, Guiyeom, Márquez, Claudio, Barat, Ana, Byrne, Annette T., Prehn, Jochen H.M., Sorribes, Joan, César, Eduardo

Journal:

Future Generation Computer Systems

Year:

2016

Language:

english

File:

PDF, 3.56 MB

english, 2016

97

Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements

Besenhard, Maximilian O., Jarzabek, Monika, O’Farrell, Alice C, Callanan, John J, Prehn, Jochen HM, Byrne, Annette T., Huber, Heinrich J.

Journal:

Journal of Theoretical Biology

Year:

2016

Language:

english

File:

PDF, 6.85 MB

english, 2016

98

Activation of Nuclear Factor κB and bcl-x Survival Gene Expression by Nerve Growth Factor Requires Tyrosine Phosphorylation of IκBα

Nguyen Truc Bui, Antonia Livolsi, Jean-Francois Peyron and Jochen H. M. Prehn

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 3.31 MB

english, 2001

99

AMP kinase—mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

Caoimhín G. Concannon, Liam P. Tuffy, Petronela Weisová, Helena P. Bonner, David Dávila, Caroline Bonner, Marc C. Devocelle, Andreas Strasser, Manus W. Ward and Jochen H.M. Prehn

Journal:

The Journal of Cell Biology

Year:

2010

File:

PDF, 2.81 MB

2010

100

AMP kinase—mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

Caoimhín G. Concannon, Liam P. Tuffy, Petronela Weisová, Helena P. Bonner, David Dávila, Caroline Bonner, Marc C. Devocelle, Andreas Strasser, Manus W. Ward and Jochen H.M. Prehn

Journal:

The Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 2.81 MB

english, 2010