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51

Somatostatin-receptor-targeted α-emitting 213Bi is therapeutically more effective than β−-emitting 177Lu in human pancreatic adenocarcinoma cells

Tapan K. Nayak, Jeffrey P. Norenberg, Tamara L. Anderson, Eric R. Prossnitz, Michael G. Stabin, Robert W. Atcher

Journal:

Nuclear Medicine and Biology

Year:

2007

Language:

english

File:

PDF, 525 KB

english, 2007

52

Enhancement of somatostatin-receptor-targeted 177Lu-[DOTA0-Tyr3]-octreotide therapy by gemcitabine pretreatment-mediated receptor uptake, up-regulation and cell cycle modulation

Tapan K. Nayak, Robert W. Atcher, Eric R. Prossnitz, Jeffrey P. Norenberg

Journal:

Nuclear Medicine and Biology

Year:

2008

Language:

english

File:

PDF, 312 KB

english, 2008

53

GPR30: a novel therapeutic target in estrogen-related disease

Eric R. Prossnitz, Larry A. Sklar, Tudor I. Oprea, Jeffrey B. Arterburn

Journal:

Trends in Pharmacological Sciences

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

54

Characterization of a human cDNA that encodes a functional receptor for platelet activating factor

Richard D. Ye, Eric R. Prossnitz, Aihua Zou, Charles G. Cochrane

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 520 KB

english, 1991

55

Lung cancer and hormone replacement therapy

Matthias Barton, Matthias R Meyer, Judy L Bolton, Eric R Prossnitz

Journal:

Year:

2010

Language:

english

File:

PDF, 81 KB

english, 2010

56

The ins and outs of GPR30: A transmembrane estrogen receptor

Eric R. Prossnitz, Tudor I. Oprea, Larry A. Sklar, Jeffrey B. Arterburn

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

57

FRET Detection of Cellular α4-Integrin Conformational Activation

Chigaev, Alexandre, Buranda, Tione, Dwyer, Denise C., Prossnitz, Eric R., Sklar, Larry A.

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

58

Integration of virtual and physical screening

Dan C. Fara, Tudor I. Oprea, Eric R. Prossnitz, Cristian G. Bologa, Bruce S. Edwards, Larry A. Sklar

Journal:

Drug Discovery Today: Technologies

Year:

2006

Language:

english

File:

PDF, 577 KB

english, 2006

59

GPER regulates endothelin-dependent vascular tone and intracellular calcium

Matthias R. Meyer, Angela S. Field, Nancy L. Kanagy, Matthias Barton, Eric R. Prossnitz

Journal:

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

60

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

Prossnitz, Eric R., Arterburn, Jeffrey B., Smith, Harriet O., Oprea, Tudor I., Sklar, Larry A., Hathaway, Helen J.

Journal:

Annual Review of Physiology

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

61

Mechanisms of Estradiol-Induced Insulin Secretion by the G Protein-Coupled Estrogen Receptor GPR30/GPER in Pancreatic β-Cells

Sharma, Geetanjali, Prossnitz, Eric R.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

62

GPER Deficiency in Male Mice Results in Insulin Resistance, Dyslipidemia, and a Proinflammatory State

Sharma, Geetanjali, Hu, Chelin, Brigman, Jonathan L., Zhu, Gang, Hathaway, Helen J., Prossnitz, Eric R.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

63

Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs

Burai, Ritwik, Ramesh, Chinnasamy, Shorty, Marvin, Curpan, Ramona, Bologa, Cristian, Sklar, Larry A., Oprea, Tudor, Prossnitz, Eric R., Arterburn, Jeffrey B.

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

64

Synthesis and Characterization of Iodinated Tetrahydroquinolines Targeting the G Protein-Coupled Estrogen Receptor GPR30

Ramesh, Chinnasamy, Nayak, Tapan K., Burai, Ritwik, Dennis, Megan K., Hathaway, Helen J., Sklar, Larry A., Prossnitz, Eric R., Arterburn, Jeffrey B.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 925 KB

english, 2010

65

Influence of Charge on Cell Permeability and Tumor Imaging of GPR30-Targeted 111 In-Labeled Nonsteroidal Imaging Agents

Nayak, Tapan K., Dennis, Megan K., Ramesh, Chinnasamy, Burai, Ritwik, Atcher, Robert W., Sklar, Larry A., Norenberg, Jeffrey P., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.

Journal:

ACS Chemical Biology

Year:

2010

Language:

english

File:

PDF, 3.97 MB

english, 2010

66

Estrogen biology: New insights into GPER function and clinical opportunities

Prossnitz, Eric R., Barton, Matthias

Journal:

Molecular and Cellular Endocrinology

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

67

Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries

Meyer, Matthias R., Fredette, Natalie C., Barton, Matthias, Prossnitz, Eric R.

Journal:

Year:

2014

Language:

english

File:

PDF, 290 KB

english, 2014

68

Cancer risk in endometrial carcinoma survivors: A longitudinal case-control study

Van Arsdale, A., Qualls, C., Conroy, E., Ford, T., Prossnitz, E., Smith, H.

Journal:

Gynecologic Oncology

Year:

2013

Language:

english

File:

PDF, 721 KB

english, 2013

69

Notes and News

Van Arsdale, A., Qualls, C., Conroy, E., Ford, T., Prossnitz, E., Smith, H.

Journal:

Year:

1981

Language:

english

File:

PDF, 303 KB

english, 1981

70

ER-alpha, PR, EGFR and GPER expression differentially correlate with survival in endometrial carcinoma

Smith, H., Qualls, C., Huang, G., Arias-Pulido, H., Howard, T., Joste, N., Van Arsdale, A., Prossnitz, E.

Journal:

Gynecologic Oncology

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

71

Localized effect of vascular aging on NADPH oxidase-mediated contractions to endothelin

Meyer, Matthias R., Barton, Matthias, Prossnitz, Eric R.

Journal:

Year:

2013

Language:

english

File:

PDF, 49 KB

english, 2013

72

Aging selectively impairs contractions to endothelin-1 but not to angiotensin II in murine carotid arteries

Meyer, Matthias R., Barton, Matthias, Prossnitz, Eric R.

Journal:

Year:

2013

Language:

english

File:

PDF, 50 KB

english, 2013

73

Introduction of d-Phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides

Lu, Jie, Hathaway, Helen J., Royce, Melanie E., Prossnitz, Eric R., Miao, Yubin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 756 KB

english, 2014

74

Functional heterogeneity of NADPH oxidase-mediated contractions to endothelin with vascular aging

Meyer, Matthias R., Barton, Matthias, Prossnitz, Eric R.

Journal:

Year:

2014

Language:

english

File:

PDF, 316 KB

english, 2014

75

Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides

Guo, Haixun, Hathaway, Helen, Royce, Melanie E., Prossnitz, Eric R., Miao, Yubin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 448 KB

english, 2013

76

Multiethnic/racial differences in risk factors and overall survival in endometrial carcinoma

Smith, H., Prossnitz, E., Arias-Pulido, H., Ford, T., Qualls, C.

Journal:

Gynecologic Oncology

Year:

2013

Language:

english

File:

PDF, 712 KB

english, 2013

77

G-Protein: Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells

Lidia Albanito, Rosamaria Lappano, Antonio Madeo, Adele Chimento, Eric R. Prossnitz, Anna Rita Cappello, Vincenza Dolce, Sergio Abonante, Vincenzo Pezzi and Marcello Maggiolini

Journal:

Environmental Health Perspectives

Year:

2008

Language:

english

File:

PDF, 2.05 MB

english, 2008

78

REMEDIES || Fines Against the Trial Lawyer

Howard B. Prossnitz

Journal:

Year:

1983

Language:

english

File:

PDF, 888 KB

english, 1983

79

GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

Scaling, Allison L., Prossnitz, Eric R., Hathaway, Helen J.

Journal:

Hormones and Cancer

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

80

Synthetic Estrogen Derivatives Demonstrate the Functionality of Intracellular GPR30

Revankar, Chetana M., Mitchell, Hugh D., Field, Angela S., Burai, Ritwik, Corona, Cesear, Ramesh, Chinnasamy, Sklar, Larry A., Arterburn, Jeffrey B., Prossnitz, Eric R.

Journal:

ACS Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.26 MB

english, 2007

81

The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

Ariazi, E. A., Brailoiu, E., Yerrum, S., Shupp, H. A., Slifker, M. J., Cunliffe, H. E., Black, M. A., Donato, A. L., Arterburn, J. B., Oprea, T. I., Prossnitz, E. R., Dun, N. J., Jordan, V. C.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

82

GPER-Targeted, 99mTc-Labeled, Nonsteroidal Ligands Demonstrate Selective Tumor Imaging and In Vivo Estrogen Binding

Nayak, T. K., Ramesh, C., Hathaway, H. J., Norenberg, J. P., Arterburn, J. B., Prossnitz, E. R.

Journal:

Molecular Cancer Research

Year:

2014

Language:

english

File:

PDF, 715 KB

english, 2014

83

Functional Capabilities of an N -Formyl Peptide Receptor−G αi2 Fusion Protein: Assemblies with G Proteins and Arrestins †

Shi, Mei, Bennett, Teresa A., Cimino, Daniel F., Maestas, Diane C., Foutz, Terry D., Gurevich, Vsevolod V., Sklar, Larry A., Prossnitz, Eric R.

Journal:

Year:

2003

Language:

english

File:

PDF, 327 KB

english, 2003

84

Effect of DOTA Position on Melanoma Targeting and Pharmacokinetic Properties of 111 In-Labeled Lactam Bridge-Cyclized α-Melanocyte Stimulating Hormone Peptide

Guo, Haixun, Yang, Jianquan, Gallazzi, Fabio, Prossnitz, Eric R., Sklar, Larry A., Miao, Yubin

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 978 KB

english, 2009

85

Synthesis and Evaluation of Novel Gonadotropin-Releasing Hormone Receptor-Targeting Peptides

Guo, Haixun, Lu, Jie, Hathaway, Helen, Royce, Melanie E., Prossnitz, Eric R., Miao, Yubin

Journal:

Bioconjugate Chemistry

Year:

2011

Language:

english

File:

PDF, 2.97 MB

english, 2011

86

Linkage Effects on Binding Affinity and Activation of GPR30 and Estrogen Receptors ERα/β with Tridentate Pyridin-2-yl Hydrazine Tricarbonyl−Re/ 99m Tc(I) Chelates

Ramesh, Chinnasamy, Bryant, Bj, Nayak, Tapan, Revankar, Chetana M., Anderson, Tamara, Carlson, Kathryn E., Katzenellenbogen, John A., Sklar, Larry A., Norenberg, Jeffrey P., Prossnitz, Eric R., Arterb

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 63 KB

english, 2006

87

Expression of GPER, ERβ, ERα, and PR in gynecologic sarcomas

Klobocista, M., Phaeton, R., Burton, E.R., Van Arsdale, A., Hebert, T., Smith, H.O., Arias-Pulido, H., Prossnitz, E., Goldberg, G.L., Huang, G.S.

Journal:

Gynecologic Oncology

Year:

2014

Language:

english

File:

PDF, 179 KB

english, 2014

88

Multiple Activation Steps of the N -Formyl Peptide Receptor †

Prossnitz, Eric R., Gilbert, Terri L., Chiang, Stephanie, Campbell, James J., Qin, Shixin, Newman, Walter, Sklar, Larry A., Ye, Richard D.

Journal:

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

89

Internalization of the Human N -Formyl Peptide and C5a Chemoattractant Receptors Occurs via Clathrin-Independent Mechanisms †

Gilbert, Terri L., Bennett, Teresa A., Maestas, Diane C., Cimino, Daniel F., Prossnitz, Eric R.

Journal:

Year:

2001

Language:

english

File:

PDF, 249 KB

english, 2001

90

G Protein-Coupled Estrogen Receptor Regulates Mammary Tumorigenesis and Metastasis

Marjon, N. A., Hu, C., Hathaway, H. J., Prossnitz, E. R.

Journal:

Molecular Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

91

The Uncoupled State of the Human Formyl Peptide Receptor

Gilbert, Terri L., Prossnitz, Eric R., Sklar, Larry A.

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1999

Language:

english

File:

PDF, 708 KB

english, 1999

92

Strategies for Positioning Fluorescent Probes and Crosslinkers on Formyl Peptide Ligands

Vilven, Janeen C., Domalewski, Mark, Prossnitz, Eric R., Ye, Richard D., Muthukumaraswamy, Natesa, Harris, Robert B., Freer, Richard J., Sklar, Larry A.

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1998

Language:

english

File:

PDF, 1.49 MB

english, 1998

93

Peptidyl Arginine Deiminase from Porphyromonas gingivalis Abolishes Anaphylatoxin C5a Activity

Bielecka, E., Scavenius, C., Kantyka, T., Jusko, M., Mizgalska, D., Szmigielski, B., Potempa, B., Enghild, J. J., Prossnitz, E. R., Blom, A. M., Potempa, J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

94

Real Time Analysis of the Affinity Regulation of 4-Integrin: THE PHYSIOLOGICALLY ACTIVATED RECEPTOR IS INTERMEDIATE IN AFFINITY BETWEEN RESTING AND Mn2+ OR ANTIBODY ACTIVATION

Chigaev, A., Blenc, A. M., Braaten, J. V., Kumaraswamy, N., Kepley, C. L., Andrews, R. P., Oliver, J. M., Edwards, B. S., Prossnitz, E. R., Larson, R. S., Sklar, L. A.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 730 KB

english, 2001

95

A Tyrosine Kinase Signaling Pathway Accounts for the Majority of Phosphatidylinositol 3,4,5-Trisphosphate Formation in Chemoattractant-stimulated Human Neutrophils

Ptasznik, A., Prossnitz, E. R., Yoshikawa, D., Smrcka, A., Traynor-Kaplan, A. E., Bokoch, G. M.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 688 KB

english, 1996

96

Chemotaxis Inhibitory Protein of Staphylococcus aureus Binds Specifically to the C5a and Formylated Peptide Receptor

Postma, B., Poppelier, M. J., van Galen, J. C., Prossnitz, E. R., van Strijp, J. A. G., de Haas, C. J. C., van Kessel, K. P. M.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 227 KB

english, 2004

97

Regulation of N-Formyl Peptide-Mediated Degranulation by Receptor Phosphorylation

Vines, C. M., Xue, M., Maestas, D. C., Cimino, D. F., Prossnitz, E. R.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 894 KB

english, 2002

98

Membrane Estrogen Receptors Stimulate Intracellular Calcium Release and Progesterone Synthesis in Hypothalamic Astrocytes

Kuo, J., Hamid, N., Bondar, G., Prossnitz, E. R., Micevych, P.

Journal:

Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 932 KB

english, 2010

99

Phosphorylation of the N-Formyl Peptide Receptor Is Required for Receptor Internalization but Not Chemotaxis

Hsu, M. H., Chiang, S. C., Ye, R. D., Prossnitz, E. R.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 132 KB

english, 1997

100

Cell Type- and Developmental Stage-specific Activation of NF- B by fMet-Leu-Phe in Myeloid Cells

Browning, D. D., Pan, Z. K., Prossnitz, E. R., Ye, R. D.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 956 KB

english, 1997