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151

Exacerbation of lichen planus during interferon alfa-2a therapy for chronic active hepatitis C

Protzer, Ulrike, Ochsendorf, Falk R., Leopolder-Ochsendorf, Anja, Holtermüller, Karl-Hans

Journal:

Gastroenterology

Year:

1993

Language:

english

File:

PDF, 377 KB

english, 1993

152

RNA Interference Mediated Suppression of HBV Transcripts Restores HBV-Specific Immunity and Enhances the Efficacy of Therapeutic Vaccination

Michler, T., Kosinska, A., Jäger, C., Röder, N., Grimm, D., Heikenwälder, M., Roggendorf, M., Protzer, U.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 109 KB

english, 2016

153

Correlation of Mutations within HDV-Protein with HLA Backgrounds of Patients Leads to Identification of Novel CD8 T Cell Epitopes

Karimzadeh, H., Budeus, B., Kosinska, A., Bauer, T., Heinold, A., Hoffmann, D., Protzer, U., Roggendorf, M.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 94 KB

english, 2016

154

Single dose hepatitis A immunisation: 7·5 year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune memory response

Mayorga, Orlando, Bühler, Silja, Jaeger, Veronika K., Bally, Seraina, Hatz, Christoph, Frösner, Gert, Protzer, Ulrike, Van Damme, Pierre, Egger, Matthias, Herzog, Christian

Journal:

The Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

155

Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions

Xia, Yuchen, Carpentier, Arnaud, Cheng, Xiaoming, Block, Peter Daniel, Zhao, Yao, Zhang, Zhensheng, Protzer, Ulrike, Jake Liang, T.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 943 KB

english, 2016

156

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize and kill tumor associated antigen STEAP1+ tumour cells in vivo

Schirmer, D., Grünewald, T., Klar, R., Schmidt, O., Wohlleber, D., Alba Rubío, R., Uckert, W., Thiel, U., Protzer, U., Busch, D., Krackhardt, A., Burdach, S., Richter, G.

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 50 KB

english, 2016

157

699. shRNA Sense Strand Neutralization Reduces Off-Targeting, Ameliorates Toxicity and Enhances Efficacy of RNAi-Based HBV Gene Therapy

Michler, Thomas, Grosse, Stefanie, Mockenhaupt, Stefan, Protzer, Ulrike, Grimm, Dirk

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015

158

PRMT5 Restricts Hepatitis B Virus Replication via Epigenetic Repression of cccDNA Transcription and Interference with pgRNA Encapsidation

Zhang, Wen, Chen, Jieliang, Wu, Min, Zhang, Xiaonan, Zhang, Min, Yue, Lei, Li, Yaming, Liu, Jiangxia, Li, Baocun, Shen, Fang, Wang, Yang, Bai, Lu, Protzer, Ulrike, Levrero, Massimo, Yuan, Zhenghong

Journal:

Year:

2017

Language:

english

File:

PDF, 3.79 MB

english, 2017

159

Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring

Körber, Nina, Behrends, Uta, Hapfelmeier, Alexander, Protzer, Ulrike, Bauer, Tanja

Journal:

Journal of Translational Medicine

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

160

Entecavir allows an unexpectedly high residual replication of HBV mutants resistant to lamivudine

Geipel, Andreas, Seiz, Pia L, Niekamp, Hauke, Neumann-Fraune, Maria, Zhang, Ke, Kaiser, Rolf, Protzer, Ulrike, Gerlich, Wolfram H, Glebe, Dieter

Journal:

Antiviral Therapy

Year:

2015

Language:

english

File:

PDF, 272 KB

english, 2015

161

Viral hepatitis: The bumpy road to animal models for HBV infection

Protzer, Ulrike

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2017

Language:

english

File:

PDF, 140 KB

english, 2017

162

Novel viral and host targets to cure hepatitis B

Ko, Chunkyu, Michler, Thomas, Protzer, Ulrike

Journal:

Current Opinion in Virology

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

163

Therapeutic vaccination for chronic hepatitis B

Kosinska, Anna D., Bauer, Tanja, Protzer, Ulrike

Journal:

Current Opinion in Virology

Year:

2017

Language:

english

File:

PDF, 622 KB

english, 2017

164

Immune Reconstitution After HCV Clearance With Direct Antiviral Agents

Werner, Jens M., Adenugba, Akinbami, Protzer, Ulrike

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 367 KB

english, 2017

165

Hepatitis B virus-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV

Wisskirchen, K., Kah, J., Metzger, K., Weigand, L., Uckert, W., Schiemann, M., Volz, T., Krackhardt, A., Dandri, M., Protzer, U.

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 67 KB

english, 2017

166

Preclinical study of a combinatorial RNAi/vaccination therapy as a potential cure for chronic hepatitis B

Michler, T., Kosinska, A., Bunse, T., Heikenwälder, M., Grimm, D., Milstein, S., Sepp-Lorenzino, L., Protzer, U.

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 55 KB

english, 2017

167

Visualizing HEV infection in human liver tissue

Protzer, Ulrike

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 272 KB

english, 2017

168

Blocking sense‐strand activity improves potency, safety and specificity of anti‐hepatitis B virus short hairpin RNA

Michler, Thomas, Große, Stefanie, Mockenhaupt, Stefan, Röder, Natalie, Stückler, Ferdinand, Knapp, Bettina, Ko, Chunkyu, Heikenwalder, Mathias, Protzer, Ulrike, Grimm, Dirk

Journal:

EMBO Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

169

Viral hepatitis and liver cancer

Ringehan, Marc, McKeating, Jane A., Protzer, Ulrike

Journal:

Philosophical Transactions Biological Sciences

Year:

2017

Language:

english

File:

PDF, 420 KB

english, 2017

170

IFN-α-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection

Li, Yong, Xia, Yuchen, Han, Meifang, Chen, Guang, Zhang, Dake, Thasler, Wolfgang E., Protzer, Ulrike, Ning, Qin

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.30 MB

english, 2017

171

Lipase inhibitor orlistat prevents hepatitis B virus infection by targeting an early step in the virus life cycle

Esser, Knud, Lucifora, Julie, Wettengel, Jochen, Singethan, Katrin, Glinzer, Almut, Zernecke, Alma, Protzer, Ulrike

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

172

Correction to ‘Viral hepatitis and liver cancer’

Ringelhan, Marc, McKeating, Jane A., Protzer, Ulrike

Journal:

Philosophical Transactions Biological Sciences

Year:

2018

File:

PDF, 205 KB

2018

173

Dégradation spécifique de l’ADN nucléaire responsable de la persistance du virus de l’hépatite B

Lucifora, Julie, Xia, Yuchen, Reisinger, Florian, Stadler, Daniela, Heikenwälder, Mathias, Protzer, Ulrike

Journal:

médecine/sciences

Year:

2014

File:

PDF, 720 KB

2014

174

Combinatorial RNAi/vaccination therapy for chronic hepatitis B achieves long-term functional cure in preclinical mouse model

Michler, T., Kosinska, A., Bunse, T., Heikenwälder, M., Grimm, D., Milstein, S., Sepp-Lorenzino, L., Protzer, U.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 51 KB

english, 2018

175

Outcome of anti-viral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes

Manske, Katrin, Kallin, Nina, König, Verena, Schneider, Annika, Kurz, Sandra, Bosch, Miriam, Welz, Meike, Cheng, Ru-Lin, Bengsch, Bertram, Steiger, Katja, Protzer, Ulrike, Thimme, Robert, Knolle, Perc

Journal:

Year:

2018

Language:

english

File:

PDF, 1.81 MB

english, 2018

176

Overcoming immune tolerance in chronic hepatitis B by therapeutic vaccination

Dembek, Claudia, Protzer, Ulrike, Roggendorf, Michael

Journal:

Current Opinion in Virology

Year:

2018

Language:

english

File:

PDF, 1.53 MB

english, 2018

177

Hepatitis B virus escapes non-canonical CTL effector function

Sandra, K., Steiger, K., Protzer, U., Knolle, P.A., Wohlleber, D.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 62 KB

english, 2018

178

Viral integration profiles in the plasma cell-free DNA from patients with HBV infection well represent tumor clone compositions during HCC development

Zhang, D., Chen, W., Zhang, K., Dong, P., Protzer, U., Zeng, C.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 198 KB

english, 2018

179

T cells grafted with HBV-specific T-cell receptors of high functional avidity achieve functional cure of HBV infection in humanized mice

Wisskirchen, K., Kah, J., Malo, A., Allweiss, L., Metzger, K., Volz, T., Krackhardt, A., Dandri-Petersen, M., Protzer, U.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 68 KB

english, 2018

180

Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells

Vincent, Isabelle E., Zannetti, Claudia, Lucifora, Julie, Norder, Helene, Protzer, Ulrike, Hainaut, Pierre, Zoulim, Fabien, Tommasino, Massimo, Trépo, Christian, Hasan, Uzma, Chemin, Isabelle, Metzger

Journal:

Year:

2011

Language:

english

File:

PDF, 957 KB

english, 2011

181

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection

Appelman, Monique D., Chakraborty, Anindita, Protzer, Ulrike, McKeating, Jane A., van de Graaf, Stan F. J., Watashi, Koichi

Journal:

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

182

Secreted Interferon-Inducible Factors Restrict Hepatitis B and C Virus Entry In Vitro

Xia, Yuchen, Cheng, Xiaoming, Blossey, Christoph K., Wisskirchen, Karin, Esser, Knud, Protzer, Ulrike

Journal:

Journal of Immunology Research

Year:

2017

Language:

english

File:

PDF, 2.44 MB

english, 2017

183

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors

Schiwon, Maren, Ehrke-Schulz, Eric, Oswald, Andreas, Bergmann, Thorsten, Michler, Thomas, Protzer, Ulrike, Ehrhardt, Anja

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 1.16 MB

english, 2018

184

Statins suppress hepatitis B virus replication and reduce hepatoma cell viability by interfering with Rho-GTPases

van de Klundert, M., Ringelhan, M., Protzer, U.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 49 KB

english, 2018

185

The hepatitis B epidemic and the urgent need for cure preparedness

Lazarus, Jeffrey V., Block, Timothy, Bréchot, Christian, Kramvis, Anna, Miller, Veronica, Ninburg, Michael, Pénicaud, Capucine, Protzer, Ulrike, Razavi, Homie, Thomas, Laura A., Wallace, Jack, Cowie,

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2018

Language:

english

File:

PDF, 390 KB

english, 2018

186

Ethische Aspekte des Dolmetschens im mehrsprachig-interkulturellen Arzt-Patienten-Verhältnis; Ethical aspects of interpreting in multilingual–intercultural physician–patient relationships;

Kliche, Ortrun, Agbih, Sylvia, Altanis-Protzer, Ute, Eulerich, Sabine, Klingler, Corinna, Neitzke, Gerald, Peters, Tim, Coors, Michael

Journal:

Ethik in der Medizin

Year:

2018

File:

PDF, 598 KB

2018

187

Ethische Aspekte des Dolmetschens im mehrsprachig-interkulturellen Arzt-Patienten-Verhältnis; Ethical aspects of interpreting in multilingual–intercultural physician–patient relationships;

Kliche, Ortrun, Agbih, Sylvia, Altanis-Protzer, Ute, Eulerich, Sabine, Klingler, Corinna, Neitzke, Gerald, Peters, Tim, Coors, Michael

Journal:

Ethik in der Medizin

Year:

2018

File:

PDF, 598 KB

2018

188

The Global Hepatitis B Virus Genotype Distribution Approximated from Available Genotyping Data

Velkov, Stoyan, Ott, Jördis, Protzer, Ulrike, Michler, Thomas

Journal:

Year:

2018

Language:

english

File:

PDF, 2.90 MB

english, 2018

189

PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice

Xia, Yuchen, Schlapschy, Martin, Morath, Volker, Roeder, Natalie, Vogt, Elisabeth I., Stadler, Daniela, Cheng, Xiaoming, Dittmer, Ulf, Sutter, Kathrin, Heikenwalder, Mathias, Skerra, Arne, Protzer, Ul

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 2.70 MB

english, 2018

190

Novel rtM204 Mutations in HBV Polymerase Confer Reduced Susceptibility to Adefovir and Tenofovir

Zhang, Ke, Bach, Christian, Fraune, Maria Neumann, Xia, Yuchen, Beggel, Bastian, Kaiser, Rolf, Schildgen, Verena, Kramer, Andrea, Schildgen, Oliver, Protzer, Ulrike

Journal:

Journal of Antivirals & Antiretrovirals

Year:

2017

Language:

english

File:

PDF, 555 KB

english, 2017

191

Towards curative therapy of chronic viral hepatitis

Bartenschlager, Ralf, Urban, Stephan, Protzer, Ulrike

Journal:

Zeitschrift für Gastroenterologie

Year:

2019

File:

PDF, 499 KB

2019

192

Comparative analysis of the antiviral effects mediated by type I and III interferons in hepatitis B virus infected hepatocytes

Bockmann, Jan-Hendrik, Stadler, Daniela, Xia, Yuchen, Ko, Chunkyu, Wettengel, Jochen M, zur Wiesch, Julian Schulze, Dandri, Maura, Protzer, Ulrike

Journal:

The Journal of Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 1.16 MB

english, 2019

193

SAT-184-Approximation of the genotype distribution within global chronic hepatitis B virus infections

Velkov, Stoyan, Protzer, Ulrike, Michler, Thomas

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 314 KB

english, 2019

194

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

Kosinska, Anna D., Moeed, Abdul, Kallin, Nina, Festag, Julia, Su, Jinpeng, Steiger, Katja, Michel, Marie-Louise, Protzer, Ulrike, Knolle, Percy A.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 6.21 MB

english, 2019

195

Revisiting Hepatitis B virus: Challenges of Curative Therapies

Hu, Jianming, Protzer, Ulrika, Siddiqui, Aleem

Journal:

Journal of Virology

Year:

2019

Language:

english

File:

PDF, 639 KB

english, 2019

196

Revisiting Hepatitis B virus: Challenges of Curative Therapies

Hu, Jianming, Protzer, Ulrika, Siddiqui, Aleem

Journal:

Journal of Virology

Year:

2019

File:

PDF, 639 KB

2019

197

Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems

Kugler, Franziska, Drexler, Ingo, Protzer, Ulrike, Hoffmann, Dieter, Moeini, Hassan

Journal:

Virology Journal

Year:

2019

Language:

english

File:

PDF, 3.83 MB

english, 2019

198

FRI-155-Characterization of a library of CD4+ T cells for T-cell therapy of HBV infection

Schreiber, Sophia, Honz, Melanie, Schiemann, Matthias, Zielinski, Christina, Protzer, Ulrike, Wisskirchen, Karin

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 59 KB

english, 2019

199

FRI-155-Characterization of a library of CD4+ T cells for T-cell therapy of HBV infection

Schreiber, Sophia, Honz, Melanie, Schiemann, Matthias, Zielinski, Christina, Protzer, Ulrike, Wisskirchen, Karin

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 59 KB

2019

200

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients

Afridi, Suliman Qadir, Moeini, Hassan, Kalali, Behnam, Wettengel, Jochen Martin, Quitt, Oliver, Semper, Raphaela, Gerhard, Markus, Protzer, Ulrike, Hoffmann, Dieter

Journal:

Brazilian Journal of Microbiology

Year:

2019

Language:

english

File:

PDF, 585 KB

english, 2019