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51

Evaluation of memory function in a population of epileptic patients and matched controls

P. Loiseau, E. Strube, D. Broustet, S. Buttellochi, C. Gomeni, P.L. Morselli

Journal:

Acta Neurologica Scandinavica

Year:

1980

Language:

english

File:

PDF, 189 KB

english, 1980

52

Estimate of the number and of the temporal sequence of measurements in a kinetic experiment

Journal:

Fundamental & Clinical Pharmacology

Year:

1990

Language:

english

File:

PDF, 344 KB

english, 1990

53

Bayesian population approaches to the analysis of dose escalation studies

Alberto Russu, Giuseppe De Nicolao, Italo Poggesi, Marta Neve, Roberto Gomeni

Journal:

Computer Methods and Programs in Biomedicine

Year:

2012

Language:

english

File:

PDF, 577 KB

english, 2012

54

Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach

Stefano Zamuner, Roberto Gomeni, Alan Bye

Journal:

Nuclear Medicine and Biology

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

55

Pharmacokinetics of N-demethyldiazepam in patients suffering from insomnia and treated with nortriptyline.

G Tognoni, R Gomeni, D de Maio, GG Alberti, P Franciosi, G Scieghi

Journal:

British Journal of Clinical Pharmacology

Year:

1975

Language:

english

File:

PDF, 564 KB

english, 1975

56

Comparison of the beta-adrenoceptor blocking properties and pharmacokinetics of SL 75212 and propranolol in man [proceedings]

G Bianchetti, M Chauvin, JF Giudicelli, R Gomeni, JR Kilborn, PL Morselli, C Richer, C Thuillez

Journal:

British Journal of Clinical Pharmacology

Year:

1979

Language:

english

File:

PDF, 302 KB

english, 1979

57

Beta-adrenoceptor blocking effects and pharmacokinetics of betaxolol (SL 75212) in man.

JF Giudicelli, M Chauvin, C Thuillez, C Richer, G Bianchetti, R Gomeni, PL Morselli

Journal:

British Journal of Clinical Pharmacology

Year:

1980

Language:

english

File:

PDF, 1.06 MB

english, 1980

58

The action of the new beta-adrenoceptor blocker SL 75212 on the metabolic response to insulin-induced hypoglycaemia in man [proceedings]

R Gomeni, JR Kilborn, PL Morselli, J Saunders, PJ Sonksen

Journal:

British Journal of Clinical Pharmacology

Year:

1979

Language:

english

File:

PDF, 169 KB

english, 1979

59

Pharmacokinetics of the new beta-adrenoceptor blocker SL 75212 in man after repeated oral administration [proceedings]

G Bianchetti, C Blatrix, R Gomeni, JR Kilborn, J Larribaud, PW Lucker, PL Morselli, JJ Thebault, S Trocherie

Journal:

British Journal of Clinical Pharmacology

Year:

1979

Language:

english

File:

PDF, 125 KB

english, 1979

60

Blood concentrations and pharmacodynamic effects of SL 75212, a new beta-adrenoceptor antagonist, after oral and intravenous administration [proceedings]

G Bianchetti, R Gomeni, JR Kilborn, PL Morselli, EA Taylor, SJ Warrington

Journal:

British Journal of Clinical Pharmacology

Year:

1979

Language:

english

File:

PDF, 327 KB

english, 1979

61

Cardiovascular effects of single oral doses of the new beta- adrenoceptor blocking agents betaxolol (SL 75212) in healthy volunteers.

PJ Cadigan, DR London, BL Pentecost, G Bianchetti, R Gomeni, JR Kilborn, PL Morselli

Journal:

British Journal of Clinical Pharmacology

Year:

1980

Language:

english

File:

PDF, 842 KB

english, 1980

62

PLASMA CONCENTRATIONS AND CARDIOTOXIC EFFECTS OF DESIPRAMINE AND PROTRIPTYLINE IN THE RAT

G. BIANCHETTI, AURORA BONACCORSI, A. CHIODAROLI, R. FRANCO, S. GARATTINI, R. GOMENI, P.L MORSELLI

Journal:

British Journal of Pharmacology

Year:

1977

Language:

english

File:

PDF, 1.03 MB

english, 1977

63

COMPARISON OF MIANSERIN WITH DESIPRAMINE, MAPROTILINE AND PHENTOLAMINE ON CARDIAC PRESYNAPTIC AND VASCULAR POSTSYNAPTIC α-ADRENOCEPTORS AND NORADRENALINE REUPTAKE IN PITHED NORMOTENSIVE RATS

I. CAVERO, R. GOMENI, FRANÇOISE LEFÈVRE-BORG, A.G. ROACH

Journal:

British Journal of Pharmacology

Year:

1980

Language:

english

File:

PDF, 1.52 MB

english, 1980

64

AUTOMOD: A polyalgorithm for an integrated analysis of linear pharmacokinetic models

Roberto Gomeni, Carla Gomeni

Journal:

Computers in Biology and Medicine

Year:

1979

Language:

english

File:

PDF, 775 KB

english, 1979

65

Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits

Icilio Cavero, Simone Fenard, Roberto Gomeni, Françoise Lefevre, Alan G. Roach

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 936 KB

english, 1978

66

The blood pressure lowering effects of intravenous versus intracerebroventricular prazosin in anaesthetised cats

Alan G. Roach, Roberto Gomeni, Mervyn Mitchard, Jean-Paul Nicolas, Icilio Cavero

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 628 KB

english, 1978

67

Trial Simulation to estimate Type I error when a population window enrichment strategy is used to improve efficiency of clinical trials in depression

Roberto Gomeni, Emilio Merlo-Pich

Journal:

European Neuropsychopharmacology

Year:

2012

Language:

english

File:

PDF, 971 KB

english, 2012

68

Modeling Alzheimer’s disease progression using the disease system analysis approach

Roberto Gomeni, Monica Simeoni, Marina Zvartau-Hind, Michael C. Irizarry, Daren Austin, Michael Gold

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

69

P.2.c.029 Improving clinical signal detection for novel antidepressants using Bayesian bootstrap monitoring and placebo estimates

E. Merlo Pich, R. Gomeni

Journal:

European Neuropsychopharmacology

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

70

P.2.c.006 Analysis of longitudinal clinical scores in major depressive disorder trials: comparison of linear and non-linear mixed effect modelling

L. Iavarone, R. Gomeni

Journal:

European Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 195 KB

english, 2009

71

P.5.a.001 Disease system analysis approach to model Alzheimer's disease progression in patients on stable acetylcholine esterase inhibitor therapy

R. Gomeni, M. Gold, M. Zvartau-Hind, M. Irizarry, D. Austin, M. Simeoni

Journal:

European Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

72

P.3.007 - Lack of interaction between amisulpride and lorazepam on psychomotor performance and memory in healthy volunteers

M.C. Perault, L. Bergougnan, A. Paillat, C. Gomeni, I. Zieleniuk, B. Vandel

Journal:

European Neuropsychopharmacology

Year:

1996

Language:

english

File:

PDF, 306 KB

english, 1996

73

Population Pharmacodynamics for Monitoring Epoetin in Athletes

Prof. Françoise Bressolle, Michel Audran, Raynald Gareau, Roy D. Baynes, Claudette Guidicelli, Roberto Gomeni

Journal:

Clinical Drug Investigation

Year:

1997

Language:

english

File:

PDF, 983 KB

english, 1997

74

A Kinetic Model for Simultaneous Fit of Clozapine and Norclozapine Concentrations in Chronic Schizophrenic Patients during Long- Term Treatment

Claire Guitton, Jean-Marie Kinowski, Roberto Gomeni, Dr Françoise Bressolle

Journal:

Clinical Drug Investigation

Year:

1998

Language:

english

File:

PDF, 281 KB

english, 1998

75

Pharmacokinetic-Pharmacodynamic Modelling of Recombinant Human Erythropoietin in Athletes

A. Gaudard, E. Varlet-Marie, M. Audran, R. Gomeni, Prof. F. Bressolle

Journal:

Clinical Drug Investigation

Year:

2003

Language:

english

File:

PDF, 3.25 MB

english, 2003

76

Exposure–Response modeling of anti-depressant treatments: the confounding role of placebo effect

Navin Goyal, Roberto Gomeni

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2013

Language:

english

File:

PDF, 792 KB

english, 2013

77

Amyotrophic lateral sclerosis disease progression model

Gomeni, Roberto, Fava, Maurizio

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Year:

2014

Language:

english

File:

PDF, 2.92 MB

english, 2014

78

Use of predictive models in CNS diseases

Gomeni, Roberto

Journal:

Current Opinion in Pharmacology

Year:

2014

Language:

english

File:

PDF, 466 KB

english, 2014

79

Population Pharmacokinetics and Prediction of Dopamine D2Receptor Occupancy After Multiple Doses of RBP‐7000, a New Sustained‐Release Formulation of Risperidone, in Schizophrenia Patients on Stable Oral Risperidone Treatment

Laffont, Celine M., Gomeni, Roberto, Zheng, Bo, Heidbreder, Christian, Fudala, Paul J., Nasser, Azmi F.

Journal:

Clinical Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 762 KB

english, 2014

80

Effects in man of progabide on prolactin release induced by haloperidol or domperidone

MENON, V, BUTT, W, THIERCELIN, J, GOMENI, R, MORSELLI, P, LONDON, D

Journal:

Psychoneuroendocrinology

Year:

1984

Language:

english

File:

PDF, 276 KB

english, 1984

81

Plasma and brain pharmacokinetics of mianserin after single and multiple dosing in mice

Altamura, Alfredo Carlo, De Novellis, Fedele, Mauri, Massimo C., Gomeni, Roberto

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

1987

Language:

english

File:

PDF, 535 KB

english, 1987

82

A latent variable approach in simultaneous modeling of longitudinal and dropout data in schizophrenia trials

Goyal, Navin, Gomeni, Roberto

Journal:

European Neuropsychopharmacology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

83

A model-based approach to characterize the population pharmacokinetics and the relationship between the pharmacokinetic and safety profiles of RBP-7000, a new, long-acting, sustained-released formulation of risperidone

Gomeni, R., Heidbreder, C., Fudala, P.J., Nasser, A.F.

Journal:

Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.81 MB

english, 2013

84

Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity

Nucci, Gianluca, Gomeni, Roberto, Poggesi, Italo

Journal:

Expert Opinion on Drug Discovery

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

85

Use of band-pass filter analysis to evaluate outcomes in an antidepressant trial for treatment resistant patients

Targum, Steven D., Burch, Daniel J., Asgharnejad, Mahnaz, Petersen, Timothy, Gomeni, Roberto, Fava, Maurizio

Journal:

European Neuropsychopharmacology

Year:

2014

Language:

english

File:

PDF, 845 KB

english, 2014

86

A Population Pharmacokinetic and Pharmacodynamic Modelling Approach to Support the Clinical Development of RBP-6000, a New, Subcutaneously Injectable, Long-Acting, Sustained-Release Formulation of Buprenorphine, for the Treatment of Opioid Dependence

Azmi F. Nasser,Christian Heidbreder,Roberto Gomeni…

Journal:

Clinical Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 2.63 MB

english, 2014

87

Identification of Patients with Impaired Hepatic Drug Metabolism Using a Limited Sampling Procedure for Estimation of Phenazone (Antipyrine) Pharmacokinetic Parameters

David Fabre,Françoise Bressolle,Roberto Goméni…

Journal:

Clinical Pharmacokinetics

Year:

1993

Language:

english

File:

PDF, 1010 KB

english, 1993

88

Does short-term placebo response predict the long-term observation? Meta-analysis on forced expiratory volume in 1 second from asthma trials

Yang, Shuying, Gomeni, Roberto, Beerahee, Misba

Journal:

Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 259 KB

english, 2014

89

Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients

Catafau, A., Penengo, M., Nucci, G., Bullich, S., Corripio, I., Parellada, E., Garcia-Ribera, C., Gomeni, R., Merlo-Pich, E.

Journal:

Journal of Psychopharmacology

Year:

2008

Language:

english

File:

PDF, 2.76 MB

english, 2008

90

A Two-Step Iterative Algorithm For Estimation In Nonlinear Mixed-Effect Models With An Evaluation In Population Pharmacokinetics

Mentré, France, Gomeni, Roberto

Journal:

Journal of Biopharmaceutical Statistics

Year:

1995

Language:

english

File:

PDF, 730 KB

english, 1995

91

Ximoprofen in Ankylosing Spondylitis: A Double Blind Placebo Controlled Dose Ranging Study

Dougados, M., Nguyen, M., Caporal, R., Legeais, J., Bouxin-Sauzet, A., Pellegri-Guegnault, B., Gomeni, C.

Journal:

Scandinavian Journal of Rheumatology

Year:

1994

Language:

english

File:

PDF, 568 KB

english, 1994

92

Monoamine Transporter Occupancy of a Novel Triple Reuptake Inhibitor in Baboons and Humans Using Positron Emission Tomography

Comley, R. A., Salinas, C. A., Slifstein, M., Petrone, M., Marzano, C., Bennacef, I., Shotbolt, P., Van der Aart, J., Neve, M., Iavarone, L., Gomeni, R., Laruelle, M., Gray, F. A., Gunn, R. N., Rabine

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 156 KB

english, 2013

93

Population pharmacokinetic modeling and simulation to guide dose selection for RBP-7000, a new sustained-release formulation of risperidone

Laffont, Celine M., Gomeni, Roberto, Zheng, Bo, Heidbreder, Christian, Fudala, Paul J., Nasser, Azmi F.

Journal:

Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.89 MB

english, 2015

94

Population modelling of patient responses in antidepressant studies: A stochastic approach

Marostica, Eleonora, Russu, Alberto, Gomeni, Roberto, Zamuner, Stefano, De Nicolao, Giuseppe

Journal:

Mathematical Biosciences

Year:

2015

Language:

english

File:

PDF, 611 KB

english, 2015

95

Endotracheal and aerosol administrations of ceftazidime in patients with nosocomial pneumonia: pharmacokinetics and absolute bioavailability.

Bressolle, F, de la Coussaye, J E, Ayoub, R, Fabre, D, Gomeni, R, Saissi, G, Eledjam, J J, Galtier, M

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1992

Language:

english

File:

PDF, 1.36 MB

english, 1992

96

Bayesian Parameter Estimates of Nelfinavir and Its Active Metabolite, Hydroxy-tert-Butylamide, in Infants Perinatally Infected with Human Immunodeficiency Virus Type 1

Payen, S., Faye, A., Compagnucci, A., Giaquinto, C., Gibbs, D., Gomeni, R., Bressolle, F., Jacqz-Aigrain, E.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2005

Language:

english

File:

PDF, 222 KB

english, 2005

97

Continuous-time Markov modelling of flexible-dose depression trials

Marostica, Eleonora, Russu, Alberto, Gomeni, Roberto, Zamuner, Stefano, De Nicolao, Giuseppe

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 514 KB

english, 2014

98

Emerging Technologies and Business Pressure: The Driving Forces for an Information Management Reengineering Strategy

Journal:

Therapeutic Innovation & Regulatory Science

Year:

2000

Language:

english

File:

PDF, 1.34 MB

english, 2000

99

In-Silico Prediction of Drug Properties in Man Using Preclinical Data and Computer-Assisted Drug Development

Gomeni, R., Falcoz, C., D'Angeli, C., Bye, A.

Journal:

Drug Information Journal

Year:

2001

Language:

english

File:

PDF, 1.32 MB

english, 2001

100

A Novel Methodology to Estimate the Treatment Effect in Presence of Highly Variable Placebo Response

Gomeni, Roberto, Goyal, Navin, Bressolle, Françoise, Fava, Maurizio

Journal:

Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 407 KB

english, 2015