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51

Enhanced Morphology and Function in Hepatocyte Spheroids: A Model of Tissue Self-Assembly

Hansen, Linda K., Hsiao, Chang-Chun, Friend, Julie R., Wu, Florence J., Bridge, Gary A., Remmel, Rory P., Cerra, Frank B., Hu, Wei-Shou

Journal:

Tissue Engineering

Year:

1998

Language:

english

File:

PDF, 6.31 MB

english, 1998

52

Glutathione S-Transferase A1 Genetic Variants Reduce Busulfan Clearance in Children Undergoing Hematopoietic Cell Transplantation

Johnson, L'Aurelle, Orchard, Paul J., Baker, K. Scott, Brundage, Richard, Cao, Qing, Wang, Xinjing, Langer, Erica, Maasah, Sharein Farag-El, Ross, Julie A., Remmel, Rory, Jacobson, Pamala A.

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

53

Functional analysis of UGT1A4 P24T and UGT1A4 L48V variant enzymes

Zhou, Jin, Argikar, Upendra A, Remmel, Rory P

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 918 KB

english, 2011

54

Separation of Clonazepam and Five Metabolites by Reverse Phase HPLC and Quantitation from Rat Liver Microsomal Incubations

Remmel, Rory P., Elmer, Gary W.

Journal:

Journal of Liquid Chromatography

Year:

1983

Language:

english

File:

PDF, 521 KB

english, 1983

55

Receding Cytochrome P450 Activity in Disassembling Hepatocyte Spheroids

Hsiao, Chang-Chun, Friend, Julie R., Wu, Florence J., Ko, Wen-Je, Remmel, Rory P., Hu, Wei-Shou

Journal:

Tissue Engineering

Year:

1999

Language:

english

File:

PDF, 5.81 MB

english, 1999

56

Gene Expression and Functional Analyses of Primary Rat Hepatocytes on Nanofiber Matrices

Brophy, Colleen M., Luebke-Wheeler, Jennifer L., Amiot, Bruce P., Remmel, Rory P., Rinaldo, Piero, Nyberg, Scott L.

Journal:

Cells Tissues Organs

Year:

2010

Language:

english

File:

PDF, 669 KB

english, 2010

57

Multigene predictors of tacrolimus exposure in kidney transplant recipients

Pulk, Rebecca A, Schladt, David S, Oetting, William S, Guan, Weihua, Israni, Ajay K, Matas, Arthur J, Remmel, Rory P, Jacobson, Pamala A

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

58

Pharmacokinetic study in pigs and in vitro metabolic characterization in pig- and human-liver microsomes reveal marked differences in disposition and metabolism of tiletamine and zolazepam (Telazol)

Kumar, Atul, Mann, Henry J., Remmel, Rory P., Beilman, Greg J., Kaila, Nitin

Journal:

Year:

2014

Language:

english

File:

PDF, 903 KB

english, 2014

59

Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis

Dawadi, Surendra, Kawamura, Shuhei, Rubenstein, Anja, Remmel, Rory, Aldrich, Courtney C.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 586 KB

english, 2016

60

Pharmacokinetic Analysis Verifies P450 Function During In Vitro and In Vivo Application of a Bioartificial Liver

NYBERG, SCOTT L., MANN, HENRY J., REMMEL, RORY P., HU, WEI-SHOU, CERRA, FRANK B.

Journal:

Year:

1993

File:

PDF, 375 KB

1993

61

Competing drug???drug interactions among multidrug antiretroviral regimens used in the treatment of HIV-infected subjects: ACTG 884

Fletcher, Courtney V., Acosta, Edward P., Cheng, Hailong, Haubrich, Richard, Fischl, Margaret, Raasch, Ralph, Mills, Charlotte, Hu, X. Joan, Katzenstein, David, Remmel, Rory P., Gulick, Roy M.

Journal:

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

62

Indinavir plasma protein binding in HIV-1-infected adults

Anderson, Peter L., Brundage, Richard C., Bushman, Lane, Kakuda, Thomas N., Remmel, Rory P., Fletcher, Courtney V.

Journal:

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

63

A TECHNIQUE FOR PORCINE HEPATOCYTE HARVEST AND DESCRIPTION OF DIFFERENTIATED METABOLIC FUNCTIONS IN STATIC CULTURE

Sielaff, Timothy D., Hu, Michael Y., Rao, Sridhar, Groehler, Kristine, Olson, Daidre, Mann, Henry J., Remmel, Rory P., Shatford, Russell A.D., Amiot, Bruce, Hu, Wei-Shou, Cerra, Frank B.

Journal:

Transplantation Journal

Year:

1995

File:

PDF, 525 KB

1995

64

Safety of High-Dose Naltrexone Treatment

Kim, Suck Won, Grant, Jon E., Yoon, Gihyun, Williams, Kyle A., Remmel, Rory P.

Journal:

Clinical Neuropharmacology

Year:

2006

Language:

english

File:

PDF, 62 KB

english, 2006

65

EFFECT OF HEMORRHAGIC SHOCK ON PHARMACOKINETICS OF A DRUG PROBE COCKTAIL FOR CYTOCHROME P450 ISOZYMES IN A PORCINE MODEL

Kumar, Atul, Remmel, Rory P., Beilman, Gregory J., Mann, Henry J.

Journal:

Year:

2007

Language:

english

File:

PDF, 264 KB

english, 2007

66

Steady-state pharmacokinetics and bioavailability of immediate-release and extended-release formulations of lamotrigine in elderly epilepsy patients: Use of stable isotope methodology

Polepally, Akshanth R., Remmel, Rory P., Brundage, Richard C., Leppik, Ilo E., Rarick, John O., Ramsay, R. Eugene, Birnbaum, Angela K.

Journal:

Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 178 KB

english, 2015

67

Simultaneous Assay of Felbamate plus Carbamazepine, Phenytoin, and Their Metabolites by Liquid Chromatography with Mobile Phase Optimization

Remmel, Rory P., Miller, Scott A., Graves, Nina M.

Journal:

Therapeutic Drug Monitoring

Year:

1990

File:

PDF, 528 KB

1990

68

Excretion of the Principal Urinary Metabolites of Phenytoin and Absolute Oral Bioavailability Determined by Use of a Stable Isotope in Patients With Epilepsy

Aliwarga, Theresa, Cloyd, James C, Goel, Varun, Brundage, Richard C, Marino, Susan E, Leppik, Ilo E, Remmel, Rory P

Journal:

Therapeutic Drug Monitoring

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

69

Extended Liver-Specific Functions of Porcine Hepatocyte Spheroids Entrapped in Collagen Gel

Arye Lazar, Henry J. Mann, Rory P. Remmel, Russell A. Shatford, Frank B. Cerra and Wei-Shou Hu

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1995

Language:

english

File:

PDF, 663 KB

english, 1995

70

CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism

Dorr, Casey R, Remmel, Rory P, Muthusamy, Amutha, Fisher, James, Moriarity, Branden, Yasuda, Kazuto, Wu, Baolin, Guan, Weihua, Schuetz, Erin G., Oetting, William S, Jacobson, Pamala A, Israni, Ajay K

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 932 KB

english, 2017

71

Concepts of Genomics in Kidney Transplantation

William S. Oetting,Casey Dorr,Rory P. Remmel…

Journal:

Current Transplantation Reports

Year:

2017

Language:

english

File:

PDF, 351 KB

english, 2017

72

Enhanced Cytochrome P450 IA1 Activity of Self-Assembled Rat Hepatocyte Spheroids

Wu, Florence J., Friend, Julie R., Remmel, Rory P., Cerra, Frank B., Hu, Wei-Shou

Journal:

Cell Transplantation

Year:

1999

Language:

english

File:

PDF, 2.85 MB

english, 1999

73

Tacrolimus Elimination in Four Patients with a CYP3A53/3 CYP3A422/22 Genotype

Scheibner, Aileen, Remmel, Rory, Schladt, David, Oetting, William, Guan, Weihua, Wu, Baolin, Dorr, Casey, Israni, Ajay, Jacobson, Pamala A

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2018

Language:

english

File:

PDF, 353 KB

english, 2018

74

Lamotrigine pharmacokinetics following oral and stable-labeled intravenous administration in young and elderly adult epilepsy patients: Effect of age

Polepally, Akshanth R., Brundage, Richard C., Remmel, Rory P., Leppik, Ilo E., Pennell, Page B., White, James R., Ramsay, R. Eugene, Kistner, Brett M., Birnbaum, Angela K.

Journal:

Year:

2018

Language:

english

File:

PDF, 796 KB

english, 2018

75

Tacrolimus Trough and Dose Intra-Patient Variability and CYP3A5 Genotype: Effects on Acute Rejection and Graft Failure in European American and African American Kidney Transplant Recipients

Seibert, Stephan R, Schladt, David P, Wu, Baolin, Guan, Weihua, Dorr, Casey, Remmel, Rory P, Matas, Arthur J, Mannon, Roslyn B, Israni, Ajay K, Oetting, William S, Jacobson, Pamala A

Journal:

Clinical Transplantation

Year:

2018

Language:

english

File:

PDF, 929 KB

english, 2018

76

Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplant Recipients

Wu, Jennifer F., Muthusamy, Amutha, Al-Ghalith, Gabriel A., Knights, Dan, Guo, Bin, Wu, Baolin, Remmel, Rory P., Schladt, David P., Alegre, Maria-Luisa, Oetting, William S., Jacobson, Pamala A., Isran

Journal:

Clinical Transplantation

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

77

Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing

Dorr, Casey R., Wu, Baolin, Remmel, Rory P., Muthusamy, Amutha, Schladt, David P., Abrahante, Juan E., Guan, Weihua, Mannon, Roslyn B., Matas, Arthur J., Oetting, William S., Jacobson, Pamala A., Isra

Journal:

The Pharmacogenomics Journal

Year:

2018

Language:

english

File:

PDF, 955 KB

english, 2018

78

Tacrolimus Troughs and Genetic Determinants of Metabolism in Kidney Transplant Recipients: A comparison of four ancestry groups

Mohamed, Moataz E., Schladt, David P., Guan, Weihua, Wu, Baolin, van Setten, Jessica, Keating, Brendan, Iklé, David, Remmel, Rory P., Dorr, Casey R., Mannon, Roslyn B., Matas, Arthur J., Israni, Ajay

Journal:

American Journal of Transplantation

Year:

2019

File:

PDF, 574 KB

2019

79

Tacrolimus Troughs and Genetic Determinants of Metabolism in Kidney Transplant Recipients: A comparison of four ancestry groups

Mohamed, Moataz E., Schladt, David P., Guan, Weihua, Wu, Baolin, van Setten, Jessica, Keating, Brendan, Iklé, David, Remmel, Rory P., Dorr, Casey R., Mannon, Roslyn B., Matas, Arthur J., Israni, Ajay

Journal:

American Journal of Transplantation

Year:

2019

Language:

english

File:

PDF, 574 KB

english, 2019

80

Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy

Birnbaum, Angela K., Karanam, Ashwin, Marino, Susan E., Barkley, Christopher M., Remmel, Rory P., Roslawski, Michaela, Gramling-Aden, Mary, Leppik, Ilo E.

Journal:

Year:

2019

File:

PDF, 414 KB

2019

81

Genetic Variants Associated With Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome-wide Association Studies

Oetting, William S., Wu, Baolin, Schladt, David P., Guan, Weihua, van Setten, Jessica, Keating, Brendan J., Iklé, David, Remmel, Rory P., Dorr, Casey R., Mannon, Roslyn B., Matas, Arthur J., Israni, A

Journal:

Transplantation Journal

Year:

2019

File:

PDF, 622 KB

2019

82

Analysis of 75 Candidate SNPs Associated With Acute Rejection in Kidney Transplant Recipients

Oetting, William S., Schladt, David P., Dorr, Casey R., Wu, Baolin, Guan, Weihua, Remmel, Rory P., Iklé, David, Mannon, Roslyn B., Matas, Arthur J., Israni, Ajay K., Jacobson, Pamala A.

Journal:

Transplantation Journal

Year:

2019

File:

PDF, 515 KB

2019

83

PharmGKB summary

Mitra-Ghosh, Taraswi, Callisto, Samuel P., Lamba, Jatinder K., Remmel, Rory P., Birnbaum, Angela K., Barbarino, Julia M., Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2020

File:

PDF, 558 KB

2020

84

Simultaneous HPLC Assay for Quantification of Indinavir, Nelfinavir, Ritonavir, and Saquinavir in Human Plasma

Remmel, Rory P, Kawle, Sagar P, Weller, Dennis, Fletcher, Courtney V

Journal:

Clinical Chemistry

Year:

2000

File:

PDF, 263 KB

2000