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51

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

Chen, William S., Lazar, Cheri S., Poenie, Martin, Tsien, Roger Y., Gill, Gordon N., Rosenfeld, Michael G.

Journal:

Year:

1987

File:

PDF, 480 KB

1987

52

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

Havran, Wendy L., Poenie, Martin, Kimura, John, Tsien, Roger, Weiss, Arthur, Allison, James P.

Journal:

Year:

1987

File:

PDF, 469 KB

1987

53

Fluorescence ratio imaging of cyclic AMP in single cells

Adams, Stephen R., Harootunian, Alec T., Buechler, Ying Ji, Taylor, Susan S., Tsien, Roger Y.

Journal:

Year:

1991

File:

PDF, 513 KB

1991

54

10.1038/35014006

Reed, John C., Matsuyama, Shigemi, Llopis, Juan, Deveraux, Quinn L., Tsien, Roger Y.

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 352 KB

english, 2000

55

10.1038/35036418

Reed, John C., Matsuyama, Shigemi, Deveraux, Quinn L., Llopis, Juan, Tsien, Roger

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

56

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

Randriamampita, Clotilde, Tsien, Roger Y.

Journal:

Year:

1993

File:

PDF, 659 KB

1993

57

Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4

Vajanaphanich, Mana, Schultz, Carsten, Rudolf, Marco T., Wasserman, Matthew, Enyedi, Péter, Craxton, Andrew, Shears, Stephen B., Tsien, Roger Y., Barrett, Kim E., Traynor-Kaplan, Alexis

Journal:

Year:

1994

File:

PDF, 501 KB

1994

58

Calcium entry signal?

Randriamampita, Clotilde, Tsien, Roger Y.

Journal:

Year:

1995

File:

PDF, 122 KB

1995

59

Spatio-temporal dynamics of cyclic AMP signals in an intact neural circuit

Hempel, Chris M., Vincent, Pierre, Adams, Stephen R., Tsien, Roger Y., Selverston, Allen I.

Journal:

Year:

1996

File:

PDF, 1.07 MB

1996

60

10.1038/42264

Tsien, Roger Y., Miyawaki, Atsushi, Llopis, Juan, Heim, Roger, McCaffery, J. Michael, Adams, Joseph A., Ikura, Mitsuhiko

Journal:

Year:

1997

Language:

english

File:

PDF, 454 KB

english, 1997

61

10.1038/71345

Pozzan, Tullio, Zaccolo, Manuela, De Giorgi, Francesca, Cho, Charles Y., Feng, Luxin, Knapp, Tom, Negulescu, Paul A., Taylor, Susan S., Tsien, Roger Y.

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 414 KB

english, 2000

62

Visualizing the mechanical activation of Src

Wang, Yingxiao, Botvinick, Elliot L., Zhao, Yihua, Berns, Michael W., Usami, Shunichi, Tsien, Roger Y., Chien, Shu

Journal:

Year:

2005

Language:

english

File:

PDF, 511 KB

english, 2005

63

Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes

Zhang, Jin, Hupfeld, Christopher J., Taylor, Susan S., Olefsky, Jerrold M., Tsien, Roger Y.

Journal:

Year:

2005

Language:

english

File:

PDF, 365 KB

english, 2005

64

Fluorescent peptides highlight peripheral nerves during surgery in mice

Whitney, Michael A, Crisp, Jessica L, Nguyen, Linda T, Friedman, Beth, Gross, Larry A, Steinbach, Paul, Tsien, Roger Y, Nguyen, Quyen T

Journal:

Nature Biotechnology

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

65

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

Shaner, Nathan C, Campbell, Robert E, Steinbach, Paul A, Giepmans, Ben N G, Palmer, Amy E, Tsien, Roger Y

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 292 KB

english, 2004

66

Mammalian cell–based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity

Martin, Brent R, Giepmans, Ben N G, Adams, Stephen R, Tsien, Roger Y

Journal:

Nature Biotechnology

Year:

2005

Language:

english

File:

PDF, 504 KB

english, 2005

67

Genetically targeted chromophore-assisted light inactivation

Tour, Oded, Meijer, Rene M, Zacharias, David A, Adams, Stephen R, Tsien, Roger Y

Journal:

Nature Biotechnology

Year:

2003

Language:

english

File:

PDF, 851 KB

english, 2003

68

Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator

Tour, Oded, Adams, Stephen R, Kerr, Rex A, Meijer, Rene M, Sejnowski, Terrence J, Tsien, Richard W, Tsien, Roger Y

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 877 KB

english, 2007

69

10.1038/ng583

Ando, Hideki, Furuta, Toshiaki, Tsien, Roger Y., Okamoto, Hitoshi

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 829 KB

english, 2001

70

Improving the photostability of bright monomeric orange and red fluorescent proteins

Shaner, Nathan C, Lin, Michael Z, McKeown, Michael R, Steinbach, Paul A, Hazelwood, Kristin L, Davidson, Michael W, Tsien, Roger Y

Journal:

Year:

2008

Language:

english

File:

PDF, 500 KB

english, 2008

71

Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor

Wallace, Damian J, zum Alten Borgloh, Stephan Meyer, Astori, Simone, Yang, Ying, Bausen, Melanie, Kügler, Sebastian, Palmer, Amy E, Tsien, Roger Y, Sprengel, Rolf, Kerr, Jason N D

Journal:

Year:

2008

Language:

english

File:

PDF, 910 KB

english, 2008

72

A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells

Hoffmann, Carsten, Gaietta, Guido, Bünemann, Moritz, Adams, Stephen R, Oberdorff-Maass, Silke, Behr, Björn, Vilardaga, Jean-Pierre, Tsien, Roger Y, Ellisman, Mark H, Lohse, Martin J

Journal:

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

73

Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors

Morishita, Wade, Tsui, Jennifer, Gaietta, Guido, Deerinck, Thomas J, Adams, Stephen R, Garner, Craig C, Tsien, Roger Y, Ellisman, Mark H, Malenka, Robert C, Ju, William

Journal:

Nature Neuroscience

Year:

2004

Language:

english

File:

PDF, 1.74 MB

english, 2004

74

Measuring calcium signaling using genetically targetable fluorescent indicators

Palmer, Amy E, Tsien, Roger Y

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 298 KB

english, 2006

75

Evolving proteins in mammalian cells using somatic hypermutation

Wang, Lei, Tsien, Roger Y

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

76

Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins

Adams, Stephen R, Tsien, Roger Y

Journal:

Nature Protocols

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

77

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

Hoffmann, Carsten, Gaietta, Guido, Zürn, Alexander, Adams, Stephen R, Terrillon, Sonia, Ellisman, Mark H, Tsien, Roger Y, Lohse, Martin J

Journal:

Nature Protocols

Year:

2010

Language:

english

File:

PDF, 872 KB

english, 2010

78

Nobel lecture: constructing and exploiting the fluorescent protein paintbox

Tsien, Roger Y.

Journal:

Integrative Biology

Year:

2010

Language:

english

File:

PDF, 5.18 MB

english, 2010

79

Photoswitching Mechanism of Cyanine Dyes

Dempsey, Graham T., Bates, Mark, Kowtoniuk, Walter E., Liu, David R., Tsien, Roger Y., Zhuang, Xiaowei

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 612 KB

english, 2009

80

Single-cell analysis of cyclic AMP response to parathyroid hormone in osteoblastic cells

Roberto Civitelli, Brian J. Bacskai, Martyn P. Mahaut-Smith, Stephen R. Adams, Louis V. Avioli, Roger Y. Tsien

Journal:

Journal of Bone and Mineral Research

Year:

1994

Language:

english

File:

PDF, 1.42 MB

english, 1994

81

FRET for studying intracellular signalling

Roger Y. Tsien, Brian J. Bacskai, Stephen R. Adams

Journal:

Trends in Cell Biology

Year:

1993

Language:

english

File:

PDF, 621 KB

english, 1993

82

Recent advances in technology for measuring and manipulating cell signals

David A Zacharias, Geoffrey S Baird, Roger Y Tsien

Journal:

Current Opinion in Neurobiology

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

83

Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo

Rosario Rizzuto, Marisa Brini, Francesca De Giorgi, Raffaela Rossi, Roger Heim, Roger Y. Tsien, Tullio Pozzan

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 349 KB

english, 1996

84

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

Roger Heim, Roger Y Tsien

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 286 KB

english, 1996

85

Microscopic properties of elementary Ca2+ release sites in non-excitable cells

David Thomas, Peter Lipp, Stephen C. Tovey, Michael J. Berridge, Wenhong Li, Roger Y. Tsien, Martin D. Bootman

Journal:

Current Biology

Year:

2000

Language:

english

File:

PDF, 362 KB

english, 2000

86

Understanding, improving and using green fluorescent proteins

Andrew B. Cubitt, Roger Heim, Stephen R. Adams, Aileen E. Boyd, Larry A. Gross, Roger Y. Tsien

Journal:

Trends in Biochemical Sciences

Year:

1995

Language:

english

File:

PDF, 2.14 MB

english, 1995

87

In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity

Olson, Emilia S., Whitney, Michael A., Friedman, Beth, Aguilera, Todd A., Crisp, Jessica L., Baik, Fred M., Jiang, Tao, Baird, Stephen M., Tsimikas, Sotirios, Tsien, Roger Y., Nguyen, Quyen T.

Journal:

Integrative Biology

Year:

2012

Language:

english

File:

PDF, 7.68 MB

english, 2012

88

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

Ellies, Lesley G., Nguyen, Quyen T., Wong, Edmund H., Gross, Larry A., Tsien, Roger Y., Olson, Emilia S., Aguilera, Todd A., Jiang, Tao

Journal:

Integrative Biology

Year:

2009

Language:

english

File:

PDF, 1.81 MB

english, 2009

89

β-Lactamase as a Marker for Gene Expression in Live Zebrafish Embryos

Erez Raz, Gregor Zlokarnik, Roger Y Tsien, Wolfgang Driever

Journal:

Developmental Biology

Year:

1998

Language:

english

File:

PDF, 336 KB

english, 1998

90

Long-term depression in cerebellar Purkinje neurons results from coincidence of nitric oxide and depolarization-induced Ca2+ transients

Varda Lev-Ram, Lewis R. Makings, Paul F. Keitz, Joseph P.Y. Kao, Roger Y. Tsien

Journal:

Year:

1995

Language:

english

File:

PDF, 852 KB

english, 1995

91

Building and breeding molecules to spy on cells and tumors

Journal:

Year:

2005

Language:

english

File:

PDF, 215 KB

english, 2005

92

Cell Penetrating Peptide Uptake by Human Tissue

Nopawan Vorasubin, Quyen To Nguyen, Emilia Olson, Todd A. Aguilera, Tao Jiang, Roger Y. Tsien

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

93

R419 – Surgery with Molecular Fluorescence Imaging Guidance

Quyen To Nguyen, Emilia Olson, Todd A. Aguilera, Nopawan Vorasubin, Tao Jiang, Roger Y. Tsien

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

94

Nitric Oxide Acts Directly in the Presynaptic Neuron to Produce Long-Term Potentiationin Cultured Hippocampal Neurons

Ottavio Arancio, Michael Kiebler, C.Justin Lee, Varda Lev-Ram, Roger Y Tsien, Eric R Kandel, Robert D Hawkins

Journal:

Year:

1996

Language:

english

File:

PDF, 691 KB

english, 1996

95

Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger

Yong Yao, Antonio V Ferrer-Montiel, Mauricio Montal, Roger Y Tsien

Journal:

Year:

1999

Language:

english

File:

PDF, 190 KB

english, 1999

96

Synergies and Coincidence Requirements between NO, cGMP, and Ca2+ in the Induction of Cerebellar Long-Term Depression

Varda Lev-Ram, Tao Jiang, Jason Wood, David S Lawrence, Roger Y Tsien

Journal:

Year:

1997

Language:

english

File:

PDF, 295 KB

english, 1997

97

Identification of Neural Circuits by Imaging Coherent Electrical Activity with FRET-Based Dyes

Timothy W. Cacciatore, Peter D. Brodfuehrer, Jesus E. Gonzalez, Tao Jiang, Stephen R. Adams, Roger Y. Tsien, William B. Kristan Jr., David Kleinfeld

Journal:

Year:

1999

Language:

english

File:

PDF, 399 KB

english, 1999

98

Optical Imaging of Calcium Transients in Neurons and Pharyngeal Muscle of C. elegans

Rex Kerr, Varda Lev-Ram, Geoff Baird, Pierre Vincent, Roger Y Tsien, William R Schafer

Journal:

Year:

2000

Language:

english

File:

PDF, 357 KB

english, 2000

99

All-Optical Histology Using Ultrashort Laser Pulses

Philbert S. Tsai, Beth Friedman, Agustin I. Ifarraguerri, Beverly D. Thompson, Varda Lev-Ram, Chris B. Schaffer, Qing Xiong, Roger Y. Tsien, Jeffrey A. Squier, David Kleinfeld

Journal:

Year:

2003

Language:

english

File:

PDF, 899 KB

english, 2003

100

A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors

Ou, Horng D., Kwiatkowski, Witek, Deerinck, Thomas J., Noske, Andrew, Blain, Katie Y., Land, Hannah S., Soria, Conrado, Powers, Colin J., May, Andrew P., Shu, Xiaokun, Tsien, Roger Y., Fitzpatrick, Ja

Journal:

Year:

2012

Language:

english

File:

PDF, 2.96 MB

english, 2012

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