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51

Stable propylphosphonic acid analogues of geranylgeranyl diphosphate possessing inhibitory activity on geranylgeranyl protein transferase

Filippo Minutolo, Valentina Asso, Simone Bertini, Laura Betti, Gianbattista Gervasi, Elisa Ghilardi, Gino Giannaccini, Giorgio Placanica, Giovanni Prota, Simona Rapposelli, Marco Macchia

Journal:

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

52

Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors

Filippo Minutolo, Michela Antonello, Silvia Barontini, Simone Bertini, Laura Betti, Romano Danesi, Gianbattista Gervasi, Gino Giannaccini, Chiara Papi, Giorgio Placanica, Simona Rapposelli, Marco Macc

Journal:

Year:

2004

Language:

english

File:

PDF, 209 KB

english, 2004

53

Conformationally restrained ceramide analogues: effects of lipophilic modifications on the antiproliferative activity

Marco Macchia, Michela Antonello, Simone Bertini, Valeria Di Bussolo, Stefano Fogli, Elisa Giovannetti, Filippo Minutolo, Simona Rapposelli, Romano Danesi

Journal:

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

54

Ceramide analogues in apoptosis: a new strategy for anticancer drug development

Marco Macchia, Simone Bertini, Stefano Fogli, Elisa Giovannetti, Filippo Minutolo, Simona Rapposelli, Romano Danesi

Journal:

Year:

2003

Language:

english

File:

PDF, 211 KB

english, 2003

55

Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion

Aldo Balsamo, Francesca Mancini, Claudio Milanese, Elisabetta Orlandini, Gabriella Ortore, Mario Pinza, Simona Rapposelli, Armando Rossello

Journal:

Year:

2003

Language:

english

File:

PDF, 320 KB

english, 2003

56

Novel Estrogen Receptor Ligands Based on an Anthranylaldoxime Structure: Role of the Phenol-Type Pseudocycle in the Binding Process

Minutolo, Filippo, Antonello, Michela, Bertini, Simone, Ortore, Gabriella, Placanica, Giorgio, Rapposelli, Simona, Sheng, Shubin, Carlson, Kathryn E., Katzenellenbogen, Benita S., Katzenellenbogen, Jo

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 362 KB

english, 2003

57

Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase

Grazia Chiellini, Simona Rapposelli, Jinge Zhu, Ilaria Massarelli, Marilena Saraceno, Anna Maria Bianucci, Lori A. Plum, Margaret Clagett-Dame, Hector F. DeLuca

Journal:

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

58

Design, synthesis and pharmacological evaluation of novel tacrine–caffeic acid hybrids as multi-targeted compounds against Alzheimer’s disease

Chao, Xiaojuan, He, Xixin, Yang, Yilin, Zhou, Xie, Jin, Minghua, Liu, Shu, Cheng, Zhiyi, Liu, Peiqing, Wang, Yuting, Yu, Jianchen, Tan, Yi, Huang, Yingjuan, Qin, Jian, Rapposelli, Simona, Pi, Rongbiao

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 572 KB

english, 2012

59

Novel adenosine 5′-triphosphate-sensitive potassium channel ligands: a patent overview (2005 – 2010)

Rapposelli, Simona

Journal:

Expert Opinion on Therapeutic Patents

Year:

2011

Language:

english

File:

PDF, 1.93 MB

english, 2011

60

Advances in Deep-Space Transponder Technology

Comparini, M.C., De Tiberis, F., Novello, R., Piloni, V., Simone, L., Gelfusa, D., Argentieri, F., Fiore, D.J., Barletta, F., Delfino, M., Cocchi, S., Marchetti, F., Delfino, A., Rapposelli, A., Basil

Journal:

Proceedings of the IEEE

Year:

2007

Language:

english

File:

PDF, 2.81 MB

english, 2007

61

Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer Against Alzheimer's Disease, Prevents Oxidative Stress-Induced Neuronal Death Through Activating Nrf2/ARE/HO-1 Pathway in HT22 Cells

Huang, Wen-Yong, Chao, Xiao-Juan, Ouyang, Ying, Liu, An-Min, He, Xi-Xin, Chen, Mei-Hui, Wang, Lan-Hua, Liu, Jun, Yu, Si-Wang, Rapposelli, Simona, Pi, Rong-Biao

Journal:

CNS Neuroscience & Therapeutics

Year:

2012

Language:

english

File:

PDF, 150 KB

english, 2012

62

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

Breschi, Maria C., Calderone, Vincenzo, Martelli, Alma, Minutolo, Filippo, Rapposelli, Simona, Testai, Lara, Tonelli, Federica, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 115 KB

english, 2006

63

Spirocyclic Benzopyran-Based Derivatives as New Anti-ischemic Activators of Mitochondrial ATP-Sensitive Potassium Channel

Breschi, Maria C., Calderone, Vincenzo, Digiacomo, Maria, Manganaro, Mariaelisa, Martelli, Alma, Minutolo, Filippo, Rapposelli, Simona, Testai, Lara, Tonelli, Federica, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

64

Sodium N -(Methylsulfonyl)- N -(4-nitro-2-phenoxyphenyl)sulfamate: A Water-Soluble Nimesulide Prodrug for Parenteral Use

Rapposelli, Simona, Digiacomo, Maria, Franchi, Silvia, Moretti, Sara, Pinza, Mario, Sacerdote, Paola, Balsamo, Aldo

Journal:

Molecular Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 246 KB

english, 2010

65

Synthesis and Biological Evaluation of (Hetero)Arylmethyloxy- and Arylmethylamine-phenyl Derivatives as Potent P-glycoprotein Modulating Agents

Colabufo, Nicola Antonio, Berardi, Francesco, Perrone, Roberto, Rapposelli, Simona, Digiacomo, Maria, Vanni, Michael, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

66

Development of Classification Models for Identifying “True” P-glycoprotein (P-gp) Inhibitors Through Inhibition, ATPase Activation and Monolayer Efflux Assays

Rapposelli, Simona, Coi, Alessio, Imbriani, Marcello, Bianucci, Anna Maria

Journal:

International Journal of Molecular Sciences

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

67

NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs

Breschi, Maria C., Calderone, Vincenzo, Digiacomo, Maria, Martelli, Alma, Martinotti, Enrica, Minutolo, Filippo, Rapposelli, Simona, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

68

2-[(3-Methoxyphenylethyl)phenoxy]-Based ABCB1 Inhibitors: Effect of Different Basic Side-Chains on Their Biological Properties

Colabufo, Nicola Antonio, Berardi, Francesco, Perrone, Roberto, Rapposelli, Simona, Digiacomo, Maria, Vanni, Michael, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 210 KB

english, 2008

69

Arylmethyloxyphenyl Derivatives: Small Molecules Displaying P-Glycoprotein Inhibition

Colabufo, Nicola Antonio, Berardi, Francesco, Perrone, Roberto, Rapposelli, Simona, Digiacomo, Maria, Balsamo, Aldo

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

70

Synthesis, Antifungal Activity, and Molecular Modeling Studies of New Inverted Oxime Ethers of Oxiconazole

Rossello, Armando, Bertini, Simone, Lapucci, Annalina, Macchia, Marco, Martinelli, Adriano, Rapposelli, Simona, Herreros, Esperanza, Macchia, Bruno

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

71

Employment of disabled people in the private sector. An analysis at the level of Italian Provinces according to article 13 of law 68/1999

Massimiliano Agovino, Agnese Rapposelli

Journal:

Quality & Quantity

Year:

2014

Language:

english

File:

PDF, 657 KB

english, 2014

72

Arylthioamides as H 2 S Donors: l -Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

Martelli, Alma, Testai, Lara, Citi, Valentina, Marino, Alice, Pugliesi, Isabella, Barresi, Elisabetta, Nesi, Giulia, Rapposelli, Simona, Taliani, Sabrina, Da Settimo, Federico, Breschi, Maria C., Cald

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 512 KB

english, 2013

73

[American Institute of Aeronautics and Astronautics 37th Joint Propulsion Conference and Exhibit - Salt Lake City,UT,U.S.A. (08 July 2001 - 11 July 2001)] 37th Joint Propulsion Conference and Exhibit - A modified bubbly isenthalpic model for numerical simulation of cavitating flows

d'Agostino, Luca, Rapposelli, Emilio, pascarella, Ciro, Ciucci, Alessandro

Year:

2001

Language:

english

File:

PDF, 1.61 MB

english, 2001

74

[American Institute of Aeronautics and Astronautics 38th AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - Indianapolis, Indiana (07 July 2002 - 10 July 2002)] 38th AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - A New Cavitating Pump Rotordynamic Test Facility

Rapposelli, Emilio, Cervone, Angelo, d'Agostino, Luca

Year:

2002

Language:

english

File:

PDF, 2.16 MB

english, 2002

75

[American Institute of Aeronautics and Astronautics 39th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Huntsville, Alabama ()] 39th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Cavitation and Rotordynamic Activities at Centrospazio

Rapposelli, Emilio, d'Agostino, Luca

Year:

2003

Language:

english

File:

PDF, 756 KB

english, 2003

76

[American Institute of Aeronautics and Astronautics 40th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Fort Lauderdale, Florida ()] 40th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Thermal Effects on Cavitation Instabilities in Helical Inducers

Rapposelli, Emilio, Cervone, Angelo, Testa, Renzo, d'Agostino, Luca

Year:

2004

Language:

english

File:

PDF, 3.67 MB

english, 2004

77

[American Institute of Aeronautics and Astronautics 41st AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - Tucson, Arizona ()] 41st AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - Experimental Characterization of Cavitation Instabilities in the Avio "FAST2" Inducer

Cervone, Angelo, Torre, Lucio, Bramanti, Cristina, Rapposelli, Emilio, d'Agostino, Luca

Year:

2005

Language:

english

File:

PDF, 2.60 MB

english, 2005

78

[American Institute of Aeronautics and Astronautics 41st AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - Tucson, Arizona ()] 41st AIAA/ASME/SAE/ASEE Joint Propulsion Conference & Exhibit - A Simplified Model for the Evaluation of the DeltaV of Ascent Trajectories

Cervone, Angelo, Rapposelli, Emilio, d'Agostino, Luca

Year:

2005

Language:

english

File:

PDF, 653 KB

english, 2005

79

Structural Evolutions of Salicylaldoximes as Selective Agonists for Estrogen Receptor β

Minutolo, Filippo, Bertini, Simone, Granchi, Carlotta, Marchitiello, Teresa, Prota, Giovanni, Rapposelli, Simona, Tuccinardi, Tiziano, Martinelli, Adriano, Gunther, Jillian R., Carlson, Kathryn E., Ka

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 946 KB

english, 2009

80

Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity

Zhu, Daqian, Chen, Meihui, Li, Min, Luo, Bingling, Zhao, Yang, Huang, Peng, Xue, Fengtian, Rapposelli, Simona, Pi, Rongbiao, Wen, Shijun

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 886 KB

english, 2013

81

SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity

Nesi, Giulia, Colabufo, Nicola Antonio, Contino, Marialessandra, Perrone, Maria Grazia, Digiacomo, Maria, Perrone, Roberto, Lapucci, Annalina, Macchia, Marco, Rapposelli, Simona

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

82

Proposal of a New Binding Orientation for Non-Peptide AT1 Antagonists: Homology Modeling, Docking and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Tuccinardi, Tiziano, Calderone, Vincenzo, Rapposelli, Simona, Martinelli, Adriano

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 1.43 MB

english, 2006

83

EV20, a Novel Anti-ErbB-3 Humanized Antibody, Promotes ErbB-3 Down-Regulation and Inhibits Tumor Growth In Vivo

Sala, Gianluca, Giovanni Rapposelli, Ilario, Ghasemi, Reza, Piccolo, Enza, Traini, Sara, Capone, Emily, Rossi, Cosmo, Pelliccia, Angela, Di Risio, Annalisa, D'Egidio, Maurizia, Tinari, Nicola, Muraro,

Journal:

Translational Oncology

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

84

Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer

Nesi, Giulia, Sestito, Simona, Mey, Valentina, Ricciardi, Simona, Falasca, Marco, Danesi, Romano, Lapucci, Annalina, Breschi, Maria C., Fogli, Stefano, Rapposelli, Simona

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

85

Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells

Minutolo, Filippo, Sala, Giusy, Bagnacani, Annalisa, Bertini, Simone, Carboni, Isabella, Placanica, Giorgio, Prota, Giovanni, Rapposelli, Simona, Sacchi, Nicoletta, Macchia, Marco, Ghidoni, Riccardo

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

86

Enantioselectivity in Cardioprotection induced by ( S )- (−)-2,2-Dimethyl- N -(4′-acetamido-benzyl)-4-spiromorpholone-chromane

Rapposelli, Simona, Calderone, Vincenzo, Cirilli, Roberto, Digiacomo, Maria, Faggi, Cristina, La Torre, Francesco, Manganaro, Mariaelisa, Martelli, Alma, Testai, Lara

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 399 KB

english, 2009

87

Monoaryl-Substituted Salicylaldoximes as Ligands for Estrogen Receptor β

Minutolo, Filippo, Bellini, Rosalba, Bertini, Simone, Carboni, Isabella, Lapucci, Annalina, Pistolesi, Letizia, Prota, Giovanni, Rapposelli, Simona, Solati, Francesca, Tuccinardi, Tiziano, Martinelli,

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

88

Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Testai, L., Rapposelli, S., Martelli, A., Breschi, M.C., Calderone, V.

Journal:

Medicinal Research Reviews

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

89

Agglomeration externalities and technical efficiency in Italian regions

Agovino, Massimiliano, Rapposelli, Agnese

Journal:

Quality & Quantity

Year:

2015

Language:

english

File:

PDF, 481 KB

english, 2015

90

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

Digiacomo, Maria, Martelli, Alma, Testai, Lara, Lapucci, Annalina, Breschi, Maria C., Calderone, Vincenzo, Rapposelli, Simona

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 829 KB

english, 2015

91

Dual targeting of ErbB-2/ErbB-3 results in enhanced antitumor activity in preclinical models of pancreatic cancer

Ghasemi, R, Rapposelli, I G, Capone, E, Rossi, C, Lattanzio, R, Piantelli, M, Sala, G, Iacobelli, S

Journal:

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

92

Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD

Digiacomo, Maria, Chen, Ziwei, Wang, Shengnan, Lapucci, Annalina, Macchia, Marco, Yang, Xiaohong, Chu, Jiaqi, Han, Yifan, Pi, Rongbiao, Rapposelli, Simona

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

93

Genetic diversity in two Italian almond collections

Rigoldi, Maria Pia, Rapposelli, Emma, De Giorgio, Donato, Resta, Paolo, Porceddu, Andrea

Journal:

Electronic Journal of Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

94

Polystyrene-Polymethylmethacrylate Block Copolymers for Lithographically Assisted Bottom-Up Assembly of Nanostructures

Borsetto, F., Kosmala, B., Fitzgerald, T.G., Shaw, Matthew T., Patterson, J., Rapposelli, P., O´Callaghan, J.M., Holmes, J.D., Morris, Michael A.

Journal:

Materials Science Forum

Year:

2007

Language:

english

File:

PDF, 1.15 MB

english, 2007

95

From Jail to Community: Innovative Strategies to Enhance Continuity Of HIV/AIDS Care

Laufer, F. N., Arriola, K. R. J., Dawson-Rose, C. S., Kumaravelu, K., Rapposelli, K. K.

Journal:

The Prison Journal

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

96

[ECS 216th ECS Meeting - Vienna, Austria (October 4 - October 9, 2009)] ECS Transactions - CARBonCHIP: Carbon Nanotubes Technology on Silicon Integrated Circuits; Some Key Results

Rapposelli, Paolo, Capraro, Bernard, Dijon, Jean, Groeseneken, Guido, Cott, Daire, Pinson, Jean, Joyeux, Xavier, Amadou, Julien, Van Noyen, Jasper, Sels, Bert

Year:

2009

Language:

english

File:

PDF, 285 KB

english, 2009

97

AFLP fingerprinting and essential oil profiling of cultivated and wild populations of SardinianSalviadesoleana

Rapposelli, Emma, Melito, Sara, Barmina, Giovanni Gabriele, Foddai, Marzia, Azara, Emanuela, Scarpa, Grazia Maria

Journal:

Genetic Resources and Crop Evolution

Year:

2015

Language:

english

File:

PDF, 757 KB

english, 2015

98

NO-Releasing Hybrids of Cardiovascular Drugs

Martelli, A., Rapposelli, S., Calderone, V.

Journal:

Current Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 110 KB

english, 2006

99

New Emerging Prospects in the Pharmacotherapy of Hypertension

Balsamo, A., Calderone, V., Rapposelli, S.

Journal:

Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents)

Year:

2008

Language:

english

File:

PDF, 582 KB

english, 2008

100

Evaluation of the Matching Process of Disabled People Through a Macroeconomic Approach: the Italian Case

Agovino, M., Rapposelli, A.

Journal:

Applied Spatial Analysis and Policy

Year:

2017

Language:

english

File:

PDF, 627 KB

english, 2017