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51

Role of Mitochondrial Remodeling in Programmed Cell Death in Drosophila melanogaster

Gaurav Goyal, Brennan Fell, Apurva Sarin, Richard J. Youle, V. Sriram

Journal:

Developmental Cell

Year:

2007

Language:

english

File:

PDF, 1.74 MB

english, 2007

52

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

Jean-Claude Martinou, Richard J. Youle

Journal:

Developmental Cell

Year:

2011

Language:

english

File:

PDF, 787 KB

english, 2011

53

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

Michael Lazarou, Seok Min Jin, Lesley A. Kane, Richard J. Youle

Journal:

Developmental Cell

Year:

2012

Language:

english

File:

PDF, 2.49 MB

english, 2012

54

Bcl-xL and caspase inhibition increase the survival of rat oxytocin and vasopressin magnocellular neurons in organotypic culture

Shirley B. House, Milan Rusnak, Xiu-Huai Liu, Richard J. Youle, Harold Gainer

Journal:

Experimental Neurology

Year:

2006

Language:

english

File:

PDF, 293 KB

english, 2006

55

The Solution Structure of Human Mitochondria Fission Protein Fis1 Reveals a Novel TPR-like Helix Bundle

Motoshi Suzuki, Seon-Yong Jeong, Mariusz Karbowski, Richard J. Youle, Nico Tjandra

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 3.16 MB

english, 2003

56

Drp-1-Dependent Division of the Mitochondrial Network Blocks Intraorganellar Ca2+ Waves and Protects against Ca2+-Mediated Apoptosis

György Szabadkai, Anna Maria Simoni, Mounia Chami, Mariusz R. Wieckowski, Richard J. Youle, Rosario Rizzuto

Journal:

Year:

2004

Language:

english

File:

PDF, 528 KB

english, 2004

57

A Chemical Inhibitor of DRP1 Uncouples Mitochondrial Fission and Apoptosis

Atsushi Tanaka, Richard J. Youle

Journal:

Year:

2008

Language:

english

File:

PDF, 187 KB

english, 2008

58

The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes

Suzanne Hoppins, Frank Edlich, Megan M. Cleland, Soojay Banerjee, J. Michael McCaffery, Richard J. Youle, Jodi Nunnari

Journal:

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

59

Stages at presentation, prognostic factors, and outcome of breast cancer in males

John Vetto, Si-Youl Jun, Darius Padduch, Heidi Eppich, Richard Shih

Journal:

The American Journal of Surgery

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

60

Scission, spores, and apoptosis: a proposal for the evolutionary origin of mitochondria in cell death induction

Stephan Frank, Everett G Robert, Richard J Youle

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

61

Structure of Bax: Coregulation of Dimer Formation and Intracellular Localization

Motoshi Suzuki, Richard J. Youle, Nico Tjandra

Journal:

Year:

2000

Language:

english

File:

PDF, 1.03 MB

english, 2000

62

De nouvelles ≪ balles magiques ≫ contre le cancer

Par Motoshi Suzuki, Richard i. Youle

Journal:

Year:

2000

File:

PDF, 585 KB

2000

63

JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis

Girish V Putcha, Siyuan Le, Stephan Frank, Cagri G Besirli, Kim Clark, Boyang Chu, Shari Alix, Richard J Youle, Art LaMarche, Anna C Maroney, Eugene M Johnson Jr.

Journal:

Year:

2003

Language:

english

File:

PDF, 651 KB

english, 2003

64

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

Stephan Frank, Brigitte Gaume, Elke S. Bergmann-Leitner, Wolfgang W. Leitner, Everett G. Robert, Frédéric Catez, Carolyn L. Smith, Richard J. Youle

Journal:

Developmental Cell

Year:

2001

Language:

english

File:

PDF, 2.01 MB

english, 2001

65

Neurodegeneration: Trouble in the cell's powerhouse

Narendra, Derek P., Youle, Richard J.

Journal:

Year:

2012

Language:

english

File:

PDF, 596 KB

english, 2012

66

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

Perciavalle, Rhonda M., Stewart, Daniel P., Koss, Brian, Lynch, John, Milasta, Sandra, Bathina, Madhavi, Temirov, Jamshid, Cleland, Megan M., Pelletier, Stéphane, Schuetz, John D., Youle, Richard J.,

Journal:

Nature Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

67

Coupling mitochondrial and cell division

Yamano, Koji, Youle, Richard J.

Journal:

Nature Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

68

Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

Sims, Joshua J, Scavone, Francesco, Cooper, Eric M, Kane, Lesley A, Youle, Richard J, Boeke, Jef D, Cohen, Robert E

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

69

S9.8 Mitofusin foci: Endogenous localization and apoptotic behavior

Megan M. Cleland, Der-Fen Suen, Kristi L. Norris, Seung-Wook Ryu, Richard J. Youle

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

70

S9.4 Altered mitochondrial dynamics caused by loss of PTEN-induced kinase 1 function, associated with recessive parkinsonism, are reversed by downregulation of Dynamin-related protein 1

Kelly Jean Thomas, Anna Sandebring, Alexandra Beilina, Marcel van der Brug, Megan M. Cleland, Ibardo Zambrano, David W. Miller, Christian Unger, Richard Cowburn, Richard Youle, Homira Behbahani, Angel

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2008

Language:

english

File:

PDF, 74 KB

english, 2008

71

Structural Insights into Cytomegalovirus Resistance to Apoptosis

Tjandra, Nico, Ma, Junhe, Edlich, Frank, Youle, Richard

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 85 KB

english, 2011

72

Apoptosis and Free Radicals

KATHERINE A. WOOD, RICHARD J. YOULE

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 934 KB

english, 1994

73

Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy

Abeliovich, Hagai, Zarei, Mostafa, Rigbolt, Kristoffer T. G., Youle, Richard J., Dengjel, Joern

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 2.84 MB

english, 2013

74

Mitochondrial Disease: mtDNA and Protein Segregation Mysteries in iPSCs

Pickrell, Alicia M., Youle, Richard J.

Journal:

Current Biology

Year:

2013

Language:

english

File:

PDF, 74 KB

english, 2013

75

MAP Kinase cross talks in oxidative stress-induced impairment of insulin secretion. Involvement in the protective activity of quercetin

Youl, Estelle, Magous, Richard, Cros, Gérard, Oiry, Catherine

Journal:

Fundamental & Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 236 KB

english, 2014

76

Damage control — How the PINK1/Parkin pathway can regulate removal of impaired mitochondria by autophagy

Youle, Richard J.

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

77

In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum

Wood, Katherine A., Dipasquale, Bruno, Youle, Richard J.

Journal:

Year:

1993

Language:

english

File:

PDF, 41.31 MB

english, 1993

78

ACYCLOVIR-RESISTANT HERPES IN AIDS TREATED WITH FOSCARNET

Youle, MichaelM., Hawkins, DavidA., Collins, Peter, Shanson, DavidC., Evans, Richard, Oliver, Nicolas, Lawrence, Adam

Journal:

Year:

1988

Language:

english

File:

PDF, 326 KB

english, 1988

79

Self and Nonself: How Autophagy Targets Mitochondria and Bacteria

Randow, Felix, Youle, Richard J.

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

80

P2120 La quercétine stimule la sécrétion d’insuline par une activation directe des canaux calciques de type L dans les cellules β pancréatiques INS-1

Bardy, G., Virsolvy, A., Youl, E., Quignard, J.-F., Cros, G., Magous, R., Richard, S., Oiry, C.

Journal:

Diabetes & Metabolism

Year:

2013

Language:

french

File:

PDF, 70 KB

french, 2013

81

Cytosol-To-Membrane Redistribution of Bax and Bcl-XLduring Apoptosis

Yi-Te Hsu, Keith G. Wolter and Richard J. Youle

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.14 MB

english, 1997

82

Receptor-Mediated Uptake of an Extracellular Bcl-xLFusion Protein Inhibits Apoptosis

Xiu-Huai Liu, JoAnn C. Castelli and Richard J. Youle

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 956 KB

english, 1999

83

Ricin Linked to Monophosphopentamannose Binds to Fibroblast Lysosomal Hydrolase Receptors, Resulting in a Cell-Type-Specific Toxin

Richard J. Youle, Gary J. Murray and David M. Neville

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 782 KB

english, 1979

84

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter, Yi-Te Hsu, Carolyn L. Smith, Amotz Nechushtan, Xu-Guang Xi and Richard J. Youle

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 2.30 MB

english, 1997

85

Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis

Amotz Nechushtan, Carolyn L. Smith, Itschak Lamensdorf, Soo-Han Yoon and Richard J. Youle

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 5.40 MB

english, 2001

86

Albumin storage protein and allergens in cottonseeds

Youle, Richard J., Huang, Anthony H. C.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1979

Language:

english

File:

PDF, 5.16 MB

english, 1979

87

Parkin Is Recruited Selectively to Impaired Mitochondria and Promotes Their Autophagy

Derek Narendra, Atsushi Tanaka, Der-Fen Suen and Richard J. Youle

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008

88

Endophilin B1 Is Required for the Maintenance of Mitochondrial Morphology

Mariusz Karbowski, Seon-Yong Jeong and Richard J. Youle

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 4.46 MB

english, 2004

89

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

Atsushi Tanaka, Megan M. Cleland, Shan Xu, Derek P. Narendra, Der-Fen Suen, Mariusz Karbowski and Richard J. Youle

Journal:

The Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 3.80 MB

english, 2010

90

Preventive Effects of Nutritional Doses of Polyphenolic Molecules on Cardiac Fibrosis Associated with Metabolic Syndrome: Involvement of Osteopontin and Oxidative Stress

Sutra, Thibault, Oiry, Catherine, Azay-Milhau, Jacqueline, Youl, Estelle, Magous, Richard, Teissèdre, Pierre-Louis, Cristol, Jean-Paul, Cros, Gérard

Journal:

Journal of Agricultural and Food Chemistry

Year:

2008

Language:

english

File:

PDF, 352 KB

english, 2008

91

A Chimeric Protein Induces Tumor Cell Apoptosis by Delivering the Human Bcl-2 Family BH3-Only Protein Bad

Antignani, Antonella, Youle, Richard J.

Journal:

Year:

2005

Language:

english

File:

PDF, 265 KB

english, 2005

92

PINK1 is degraded through the N-end rule pathway

Yamano, Koji, Youle, Richard J

Journal:

Year:

2013

Language:

english

File:

PDF, 4.41 MB

english, 2013

93

Generation and Characterization of Species-Specific Anti-Bcl-X L Monoclonal Antibodies

Hsu, Yi-Te, Hou, Qi, Cymbalyuk, Eugene, Youle, Richard

Journal:

Hybridoma and Hybridomics

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

94

The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

Jin, Seok Min, Youle, Richard J

Journal:

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

95

Interferon Enhances the Activity of the Anticancer Ribonuclease, Onconase

Vasandani, Veena M., Castelli, Joann C., Hott, Jonathan S., Saxena, Shailendra, Mikulski, Stanislaw M., Youle, Richard J.

Journal:

Journal of Interferon & Cytokine Research

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

96

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

Pickrell, Alicia M., Youle, Richard J.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.79 MB

english, 2015

97

Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter

Hasson, Samuel A., Fogel, Adam I., Wang, Chunxin, MacArthur, Ryan, Guha, Rajarshi, Heman-Ackah, Sabrina, Martin, Scott, Youle, Richard J., Inglese, James

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

98

Ribonucleases || Antitumor RNases

Youle, Richard J.

Year:

1997

Language:

english

File:

PDF, 1.49 MB

english, 1997

99

Conformation of BCL-XL upon Membrane Integration

Yao, Yong, Fujimoto, Lynn M., Hirshman, Nathan, Bobkov, Andrey A., Antignani, Antonella, Youle, Richard J., Marassi, Francesca M.

Journal:

Journal of Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.71 MB

english, 2015

100

A Randomized, Double‐Blind Trial of Valaciclovir Prophylaxis for Cytomegalovirus Disease in Patients with Advanced Human Immunodeficiency Virus Infection

Feinberg, Judith E., Hurwitz, Shelley, Cooper, David, Sattler, Fred R., MacGregor, Rob Roy, Powderly, William, Holland, Gary N., Griffiths, Paul D., Pollard, Richard B., Youle, Michael, Gill, M. John,

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998