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51

Osteopontin deficiency impairs wear debris–induced osteolysis via regulation of cytokine secretion from murine macrophages

Sadanori Shimizu, Naoki Okuda, Norihiko Kato, Susan R. Rittling, Atsushi Okawa, Kenichi Shinomiya, Takeshi Muneta, David T. Denhardt, Masaki Noda, Kunikazu Tsuji, Yoshinori Asou

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 289 KB

english, 2010

52

Unexpected Enhancement of Thrombin Inhibitor Potency with o-Aminoalkylbenzylamides in the P1 Position.

Kenneth E. Rittle, et al. et al.

Journal:

Year:

2004

File:

PDF, 75 KB

2004

53

Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1

James C. Barrow, Kenneth E. Rittle, Phung L. Ngo, Harold G. Selnick, Samuel L. Graham, Steven M. Pitzenberger, Georgia B. McGaughey, Dennis Colussi, Ming-Tain Lai, Qian Huang, Katherine Tugusheva, Amy

Journal:

Year:

2007

Language:

english

File:

PDF, 302 KB

english, 2007

54

Cover Picture: Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1 (ChemMedChem 7/2007)

James C. Barrow, Kenneth E. Rittle, Phung L. Ngo, Harold G. Selnick, Samuel L. Graham, Steven M. Pitzenberger, Georgia B. McGaughey, Dennis Colussi, Ming-Tain Lai, Qian Huang, Katherine Tugusheva, Amy

Journal:

Year:

2007

File:

PDF, 31 KB

2007

55

Regulatory role of DC-derived osteopontin in systemic allergen sensitization

Masatsugu Kurokawa, Satoshi Konno, Ayumu Takahashi, Beverly Plunkett, Susan R. Rittling, Yutaka Matsui, Shigeyuki Kon, Junko Morimoto, Toshimitsu Uede, Satoshi Matsukura, Fumio Kokubu, Mitsuru Adachi,

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

56

Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration

Chikako Hayashi, Susan Rittling, Tadayoshi Hayata, Teruo Amagasa, David Denhardt, Yoichi Ezura, Kazuhisa Nakashima, Masaki Noda

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

57

Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications

Christian C. Kazanecki, Aaron J. Kowalski, Tony Ding, Susan R. Rittling, David T. Denhardt

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 340 KB

english, 2007

58

Transforming growth factor-β1 regulation of ATF-3 and identification of ATF-3 target genes in breast cancer cells

Sukyee Kwok, Susan R. Rittling, Nicola C. Partridge, Chellakkan S. Benson, Mayuranathan Thiyagaraj, Narasimhan Srinivasan, Nagarajan Selvamurugan

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 218 KB

english, 2009

59

Amino acid pools in cultured muscle cells

Robert B. Low, William S. Stirewalt, Susan R. Rittling, Robert C. Woodworth

Journal:

Journal of Cellular Biochemistry

Year:

1984

Language:

english

File:

PDF, 473 KB

english, 1984

60

Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: Evidence of a role for an intracellular form of osteopontin

Baoqian Zhu, Keiko Suzuki, Harvey A. Goldberg, Susan R. Rittling, David T. Denhardt, Christopher A.G. McCulloch, Jaro Sodek

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

61

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-α expression and non-programmed cell death

Andre Paes Batista da Silva, Aaron Pollett, Susan R. Rittling, David T. Denhardt, Jaro Sodek, Ron Zohar

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 552 KB

english, 2006

62

Discovery and expanded SAR of 4,4-disubstituted quinazolin-2-ones as potent T-type calcium channel antagonists

Kelly-Ann S. Schlegel, Zhi-Qiang Yang, Thomas S. Reger, Youheng Shu, Rowena Cube, Kenneth E. Rittle, Phung Bondiskey, Mark G. Bock, George D. Hartman, Cuyue Tang, Jeanine Ballard, Yuhsin Kuo, Thomayan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 615 KB

english, 2010

63

Pyridyl amides as potent inhibitors of T-type calcium channels

Thomas S. Reger, Zhi-Qiang Yang, Kelly-Ann S. Schlegel, Youheng Shu, Christa Mattern, Rowena Cube, Kenneth E. Rittle, Georgia B. McGaughey, George D. Hartman, Cuyue Tang, Jeanine Ballard, Yuhsin Kuo,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 870 KB

english, 2011

64

A new amine resolution method and its application to 3-aminobenzodiazepines

Kenneth E Rittle, Ben E Evans, Mark G Bock, Robert M DiPardo, Willie L Whitter, Carl F Homnick, Daniel F Veber, Roger M Freidinger

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 138 KB

english, 1987

65

An expedient synthesis of 3-amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one

Mark G Bock, Robert M DiPardo, Ben E Evans, Kenneth E Rittle, Daniel F Veber, Roger M Freidinger

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 204 KB

english, 1987

66

Multipurpose receptor ligands: β-carboline cholecystokinin antagonists

Ben E. Evans, Kenneth E. Rittle, Raymond S.L. Chang, Victor J. Lotti, Stephen B. Freedman, Roger M. Freidinger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 312 KB

english, 1993

67

Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)

Philippe G Nantermet, James C Barrow, George F Lundell, Janetta M Pellicore, Kenneth E Rittle, MaryBeth Young, Roger M Freidinger, Thomas M Connolly, Cindra Condra, Jerzy Karczewski, Rodney A Bednar,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 129 KB

english, 2002

68

Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position

Kenneth E. Rittle, James C. Barrow, Kellie J. Cutrona, Kristen L. Glass, Julie A. Krueger, Lawrence C. Kuo, S.Dale Lewis, Bobby J. Lucas, Daniel R. McMasters, Matthew M. Morrissette, Philippe G. Nante

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 230 KB

english, 2003

69

Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene

Noiri, Eisei, Dickman, Kate, Miller, Frederick, Romanov, Galina, Romanov, Victor I, Shaw, Robert, Chambers, Ann F, Rittling, Susan R, Denhardt, David T, Goligorsky, Michael S

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 507 KB

english, 1999

70

Cell cycle dependent genes inducible by different mitogens in cells from different species

C. W. Gibson, S. R. Rittling, R. R. Hirschhorn, L. Kaczmarek, B. Calabretta, C. D. Stiles, R. Baserga

Journal:

Molecular and Cellular Biochemistry

Year:

1986

Language:

english

File:

PDF, 726 KB

english, 1986

71

A Mouse Model of Breast Cancer Metastasis to the Choroid of the Eye

Misty Kuhn, Sarah Shah, Tajneen Natasha, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

72

The role of prior knowledge in the development of strategy flexibility: the case of computational estimation

Jon R. Star, Bethany Rittle-Johnson, Kathleen Lynch, Natasha Perova

Journal:

Year:

2009

Language:

english

File:

PDF, 302 KB

english, 2009

73

Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation

Shaun R. Stauffer, Matthew G. Stanton, Alison R. Gregro, Melissa A. Steinbeiser, Jennifer R. Shaffer, Philippe G. Nantermet, James C. Barrow, Kenneth E. Rittle, Dennis Collusi, Amy S. Espeseth, Ming-T

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 281 KB

english, 2007

74

Protective role of osteopontin in endodontic infection

Susan R. Rittling, Craig Zetterberg, Kader Yagiz, Stephen Skinner, Noriyuki Suzuki, Akira Fujimura, Hajime Sasaki

Journal:

Year:

2010

Language:

english

File:

PDF, 383 KB

english, 2010

75

The presence of an audience and list type (competitional or noncompetitional) as joint determinants of performance in paired-associates learning

Nickolas B. Cottrell, Robert H. Rittle, Dennis L Wack

Journal:

Journal of Personality

Year:

1967

Language:

english

File:

PDF, 442 KB

english, 1967

76

Promoting Transfer: Effects of Self-Explanation and Direct Instruction

Bethany Rittle-Johnson

Journal:

Child Development

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

77

Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: Osteopontin localization

EVAN, ANDREW P, COE, FREDRIC L, RITTLING, SUSAN R, BLEDSOE, SHARON M, SHAO, YOUZHI, LINGEMAN, JAMES E, WORCESTER, ELAINE M

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 754 KB

english, 2005

78

Characterization of osteopontin expression and function after status epilepticus

Karin Borges, Marla Gearing, Susan Rittling, Esben S. Sorensen, Robert Kotloski, David T. Denhardt, Raymond Dingledine

Journal:

Year:

2008

Language:

english

File:

PDF, 898 KB

english, 2008

79

Pertussis—The Case for Universal Vaccination

Journal:

Journal for Specialists in Pediatric Nursing

Year:

2010

Language:

english

File:

PDF, 202 KB

english, 2010

80

Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro

Susan R. Rittling, Hiroko N. Matsumoto, Marc D. Mckee, Antonio Nanci, Xiao-Rong An, Kristine E. Novick, Aaron J. Kowalski, Masaki Noda, David T. Denhardt

Journal:

Journal of Bone and Mineral Research

Year:

1998

Language:

english

File:

PDF, 444 KB

english, 1998

81

Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues

Hiroyuki Nemoto, Susan R. Rittling, Hiroyuki Yoshitake, Koichi Furuya, Teruo Amagasa, Kunikazu Tsuji, Akira Nifuji, David T. Denhardt, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

82

Resistance to Unloading-Induced Three-Dimensional Bone Loss in Osteopontin-Deficient Mice

Muneaki Ishijima, Kunikazu Tsuji, Susan R. Rittling, Teruhito Yamashita, Hisashi Kurosawa, David T. Denhardt, Akira Nifuji, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 4.73 MB

english, 2002

83

Colocalization of Intracellular Osteopontin With CD44 Is Associated With Migration, Cell Fusion, and Resorption in Osteoclasts

K. Suzuki, B. Zhu, S. R. Rittling, D. T. Denhardt, H. A. Goldberg, C. A. G. Mcculloch, J. Sodek

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 2.80 MB

english, 2002

84

Osteopontin-Deficiency Suppresses Growth of B16 Melanoma Cells Implanted in Bone and Osteoclastogenesis in Co-Cultures

Yoshio Ohyama, Hiroyuki Nemoto, Susan Rittling, Kunikazu Tsuji, Teruo Amagasa, David T Denhardt, Akira Nifuji, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2004

Language:

english

File:

PDF, 903 KB

english, 2004

85

Osteopontin Expression in Osteoblasts and Osteocytes During Bone Formation Under Mechanical Stress in the Calvarial Suture In Vivo

Mikihiko Morinobu, Muneaki Ishijima, Susan R Rittling, Kunikazu Tsuji, Haruyasu Yamamoto, Akira Nifuji, David T Denhardt, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2003

Language:

english

File:

PDF, 3.37 MB

english, 2003

86

Mammary tumor development in MMTV-c-myc/MMTV-v-Ha-ras transgenic mice is unaffected by osteopontin deficiency

Fei Feng, Susan R. Rittling

Journal:

Breast Cancer Research and Treatment

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

87

Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter

David T. Denhardt, Devra Mistretta, Ann F. Chambers, Shuba Krishna, Joseph F. Porter, Srilatha Raghuram, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

88

Novel murine mammary epithelial cell lines that form osteolytic bone metastases: Effect of strain background on tumor homing

Yanping Chen, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

89

Predictors of Social Anxiety in Children and Adolescents with Sickle Cell Disease

Janelle L. Wagner, Mark Connelly, Ronald T. Brown, Lloyd “Chip” Taylor, Carrie Rittle, Barbara Wall-Cloues

Journal:

Journal of Clinical Psychology in Medical Settings

Year:

2004

Language:

english

File:

PDF, 115 KB

english, 2004

90

Cholecystokinin antagonists. Synthesis and biological evaluation of 3-substituted 1,4-benzodiazepin-2-amines

Bock, Mark G., DiPardo, Robert M., Evans, Ben E., Rittle, Kenneth E., Freidinger, Roger M., Chang, Raymond S. L., Lotti, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 712 KB

english, 1988

91

Discovery of 1,4-Substituted Piperidines as Potent and Selective Inhibitors of T-Type Calcium Channels

Yang, Zhi-Qiang, Barrow, James C., Shipe, William D., Schlegel, Kelly-Ann S., Shu, Youheng, Yang, F. Vivien, Lindsley, Craig W., Rittle, Kenneth E., Bock, Mark G., Hartman, George D.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 501 KB

english, 2008

92

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

Evans, B. E., Rittle, K. E., Bock, M. G., DiPardo, R. M., Freidinger, R. M., Whitter, W. L., Lundell, G. F., Veber, D. F., Anderson, P. S.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.29 MB

english, 1988

93

Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice

Brenda Bourassa, Sara Monaghan, Susan R. Rittling

Journal:

Cellular Immunology

Year:

2004

Language:

english

File:

PDF, 315 KB

english, 2004

94

Osteopontin is associated with nuclear factor κB gene expression during tail-suspension-induced bone loss

Muneaki Ishijima, Yoichi Ezura, Kunikazu Tsuji, Susan R. Rittling, Hisashi Kurosawa, David T. Denhardt, Mitsuru Emi, Akira Nifuji, Masaki Noda

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

95

Promoter-independent regulation of vimentin expression in mammary epithelial cells by val12 ras and TGFβ

Bradley Yates, Craig Zetterberg, Vaishali Rajeev, Michael Reiss, Susan R. Rittling

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 1.54 MB

english, 2007

96

Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation

Kader Yagiz, Susan R Rittling

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 2.75 MB

english, 2009

97

Detection of Mouse Osteopontin by Western Blotting

Susan R. Rittling, Fei Feng

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 379 KB

english, 1998

98

Cell Cycle-Dependent Regulation of Ca2+ in Young and Senescent WI-38 Cells

Katherine M. Brooks-Frederich, Felicia L. Cianciarulo, Susan R. Rittling, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1993

File:

PDF, 203 KB

1993

99

Clonal Nature of Spontaneously Immortalized 3T3 Cells

Susan R. Rittling

Journal:

Experimental Cell Research

Year:

1996

Language:

english

File:

PDF, 215 KB

english, 1996

100

Ferritin synthesis in rat L-6 cells: Response to iron challenge

Susan R. Rittling, Robert C. Woodworth

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 1.37 MB

english, 1983