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1

Inorganic Nanoparticles for Cancer Therapy: A Transition from Lab to Clinic

Bayda, Samer, Hadla, Mohamad, Palazzolo, Stefano, Riello, Pietro, Corona, Giuseppe, Toffoli, Giuseppe, Rizzolio, Flavio

Journal:

Current Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 5.93 MB

english, 2018

2

Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer

Granchi, Carlotta, Fortunato, Serena, Meini, Serena, Rizzolio, Flavio, Caligiuri, Isabella, Tuccinardi, Tiziano, Lee, Hyang Yeon, Hergenrother, Paul J., Minutolo, Filippo

Journal:

Journal of Agricultural and Food Chemistry

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

3

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017)

Granchi, Carlotta, Caligiuri, Isabella, Minutolo, Filippo, Rizzolio, Flavio, Tuccinardi, Tiziano

Journal:

Expert Opinion on Therapeutic Patents

Year:

2017

Language:

english

File:

PDF, 2.92 MB

english, 2017

4

Nanomedicine in Cancer Pathology

Rizzolio, Flavio

Journal:

Current Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 152 KB

english, 2018

5

Optimization of a benzoylpiperidine class identifies a highly potent and selective reversible monoacylglycerol lipase (MAGL) inhibitor

Granchi, Carlotta, Lapillo, Margherita, Glasmacher, Sandra, Bononi, Giulia, Licari, Cristina, Poli, Giulio, el Boustani, Maguie, Caligiuri, Isabella, Rizzolio, Flavio, Gertsch, Jürg, Macchia, Marco, M

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 1.09 MB

2019

6

Nanomedicine to target multidrug resistant tumors

Lepeltier, Elise, Rijo, Patricia, Rizzolio, Flavio, Popovtzer, Rachela, Petrikaite, Vilma, Assaraf, Yehuda G., Passirani, Catherine

Journal:

Drug Resistance Updates

Year:

2020

File:

PDF, 4.65 MB

2020

7

Supercritical CO2 extraction of natural antibacterials from low value weeds and agro-waste

Campalani, Carlotta, Chioggia, Francesco, Amadio, Emanuele, Gallo, Michele, Rizzolio, Flavio, Selva, Maurizio, Perosa, Alvise

Journal:

Journal of CO2 Utilization

Year:

2020

File:

PDF, 1.14 MB

2020

8

Self-therapeutic nanomaterials for Cancer therapy: A review

Adeel, Muhammad, DUZAGAC, Fahriye, Canzonieri, Vincenzo, Rizzolio, Flavio

Journal:

ACS Applied Nano Materials

Year:

2020

File:

PDF, 3.35 MB

2020

9

An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)

Bononi, Giulia, Poli, Giulio, Rizzolio, Flavio, Tuccinardi, Tiziano, Macchia, Marco, Minutolo, Filippo, Granchi, Carlotta

Journal:

Expert Opinion on Therapeutic Patents

Year:

2020

File:

PDF, 1.01 MB

2020

10

RB gene family: Genome-wide ChIP approaches could open undiscovered roads

Flavio Rizzolio, Luca Esposito, Debora Muresu, Robert Fratamico, Ranna Jaraha, Gianluca Vosa Caprioli, Antonio Giordano

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

11

Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls

Paolo Poggio, Juan B. Grau, Benjamin C. Field, Rachana Sainger, William F. Seefried, Flavio Rizzolio, Giovanni Ferrari

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 1.97 MB

english, 2011

12

1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties

Alec D. Lebsack, Jason C. Rech, Bryan J. Branstetter, Natalie A. Hawryluk, Jeffrey E. Merit, Brett Allison, Raymond Rynberg, Johnathan Buma, Michele Rizzolio, Nadia Swanson, Hong Ao, Michael P. Maher,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 714 KB

english, 2010

13

1,2-Elimination of alcohol from homoallyl ethers under the influence of mixed metal bases

Christian Margot, Michèle Rizzolio, Manfred Schlosser

Journal:

Year:

1990

Language:

english

File:

PDF, 1.11 MB

english, 1990

14

Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: a hypothesis

Flavio Rizzolio, Cinzia Sala, Simone Alboresi, Silvia Bione, Serena Gilli, Mara Goegan, Tiziano Pramparo, Orsetta Zuffardi, Daniela Toniolo

Journal:

Year:

2007

Language:

english

File:

PDF, 516 KB

english, 2007

15

Spontaneous Gelation of a Novel Histamine H4 Receptor Antagonist in Aqueous Solution

Alexey Popov, Magali B. Hickey, Rupa Hiremath, Matthew Peterson, Poe Ratanabanangkoon, Michele Rizzolio, Sara Waggener, Yuri Zimenkov

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 777 KB

english, 2011

16

A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28

Rossetti, Francesca, Rizzolio, Flavio, Pramparo, Tiziano, Sala, Cinzia, Bione, Silvia, Bernardi, Franca, Goegan, Mara, Zuffardi, Orsetta, Toniolo, Daniela

Journal:

European Journal of Human Genetics

Year:

2004

Language:

english

File:

PDF, 147 KB

english, 2004

17

Pharmaco-metabolomics: An emerging “omics” tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets

Giuseppe Corona, Flavio Rizzolio, Antonio Giordano, Giuseppe Toffoli

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 75 KB

english, 2012

18

Critical choices for modeling breast cancer in transgenic mouse models

Isabella Caligiuri, Flavio Rizzolio, Silvia Boffo, Antonio Giordano, Giuseppe Toffoli

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

19

Covalently bound fatty acids in membrane proteins of some sponges

Eser Ayanoglu, Michele Rizzolio, Stacey Beaulieu, Julie Roberts, Orhan Oz, Carl Djerassi

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1990

Language:

english

File:

PDF, 525 KB

english, 1990

20

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold

Clementina Manera, Giuseppe Saccomanni, Anna Maria Malfitano, Simone Bertini, Francesca Castelli, Chiara Laezza, Alessia Ligresti, Valentina Lucchesi, Tiziano Tuccinardi, Flavio Rizzolio, Maurizio Bif

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 685 KB

english, 2012

21

Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist

Michael P. Maher, Anindya Bhattacharya, Hong Ao, Nadia Swanson, Nyan-Tsz Wu, Jamie Freedman, Mena Kansagara, Brian Scott, Dong H. Li, William A. Eckert III, Yi Liu, Kia Sepassi, Michele Rizzolio, Anne

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 866 KB

english, 2011

22

Spatial and temporal expression of POF1B, a gene expressed in epithelia

Flavio Rizzolio, Silvia Bione, Antonello Villa, Emilio Berti, Arianna Cassetti, Alessandro Bulfone, Carla Tribioli, Daniela Toniolo

Journal:

Gene Expression Patterns

Year:

2007

Language:

english

File:

PDF, 2.21 MB

english, 2007

23

The cholecystokinin CCK2 receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat

TD Barrett, G Lagaud, P Wagaman, JM Freedman, W Yan, L Andries, MC Rizzolio, MF Morton, NP Shankley

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

24

Dissecting Pin1 and phospho-pRb regulation

Flavio Rizzolio, Isabella Caligiuri, Chiara Lucchetti, Robert Fratamico, Valentina Tomei, Gaia Gallo, Alexis Agelan, Giovanni Ferrari, Giuseppe Toffoli, Andres J. Klein-Szanto, Antonio Giordano

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

25

A Mutation in the Rett Syndrome Gene, MECP2, Causes X-Linked Mental Retardation and Progressive Spasticity in Males

Ilaria Meloni, Mirella Bruttini, Ilaria Longo, Francesca Mari, Flavio Rizzolio, Patrizia D'Adamo, Koenraad Denvriendt, Jean-Pierre Fryns, Daniela Toniolo, Alessandra Renieri

Journal:

The American Journal of Human Genetics

Year:

2000

Language:

english

File:

PDF, 129 KB

english, 2000

26

Research Highlights

Lucchetti, Chiara, Rizzolio, Flavio, Castronovo, Matteo, Toffoli, Giuseppe

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 494 KB

english, 2011

27

Emerging molecular networks in Burkitt's lymphoma

Mangani, Davide, Roberti, Annalisa, Rizzolio, Flavio, Giordano, Antonio

Journal:

Journal of Cellular Biochemistry

Year:

2013

Language:

english

File:

PDF, 63 KB

english, 2013

28

R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair

Mario Federico, Catherine E Symonds, Luigi Bagella, Flavio Rizzolio, Daniele Fanale, Antonio Russo, Antonio Giordano

Journal:

Molecular Cancer

Year:

2010

Language:

english

File:

PDF, 2.99 MB

english, 2010

29

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

Alessio, Nicola, Bohn, Wolfgang, Rauchberger, Verena, Rizzolio, Flavio, Cipollaro, Marilena, Rosemann, Michael, Irmler, Martin, Beckers, Johannes, Giordano, Antonio, Galderisi, Umberto

Journal:

Cellular and Molecular Life Sciences

Year:

2013

Language:

english

File:

PDF, 1008 KB

english, 2013

30

The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation

Marchesi, Irene, Fiorentino, Francesco Paolo, Rizzolio, Flavio, Giordano, Antonio, Bagella, Luigi

Journal:

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

31

Pyrazole-based arylalkyne Cathepsin S inhibitors. Part III: Modification of P4 region

Wiener, John J.M., Wickboldt, Alvah Tyson, Nguyen, Steven, Sun, Siquan, Rynberg, Raymond, Rizzolio, Michele, Karlsson, Lars, Edwards, James P., Grice, Cheryl A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.56 MB

english, 2013

32

Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy

Kumar, Vinit, Toffoli, Giuseppe, Rizzolio, Flavio

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 318 KB

english, 2013

33

Identification of New Fyn Kinase Inhibitors Using a FLAP-Based Approach

Poli, Giulio, Tuccinardi, Tiziano, Rizzolio, Flavio, Caligiuri, Isabella, Botta, Lorenzo, Granchi, Carlotta, Ortore, Gabriella, Minutolo, Filippo, Schenone, Silvia, Martinelli, Adriano

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 1.89 MB

english, 2013

34

Metabolomics Biomarkers of Frailty in Elderly Breast Cancer Patients

Corona, Giuseppe, Polesel, Jerry, Fratino, Lucia, Miolo, Gianmaria, Rizzolio, Flavio, Crivellari, Diana, Addobbati, Riccardo, Cervo, Silvia, Toffoli, Giuseppe

Journal:

Journal of Cellular Physiology

Year:

2014

Language:

english

File:

PDF, 413 KB

english, 2014

35

Identification and characterization of a new reversible MAGL inhibitor

Tuccinardi, Tiziano, Granchi, Carlotta, Rizzolio, Flavio, Caligiuri, Isabella, Battistello, Vittoria, Toffoli, Giuseppe, Minutolo, Filippo, Macchia, Marco, Martinelli, Adriano

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

36

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

Casazza, Andrea, Laoui, Damya, Wenes, Mathias, Rizzolio, Sabrina, Bassani, Nicklas, Mambretti, Marco, Deschoemaeker, Sofie, Van Ginderachter, Jo A., Tamagnone, Luca, Mazzone, Massimiliano

Journal:

Year:

2013

Language:

english

File:

PDF, 5.50 MB

english, 2013

37

Pin1 and Nuclear Receptors: A New Language?

La Montagna, Raffaele, Caligiuri, Isabella, Giordano, Antonio, Rizzolio, Flavio

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 158 KB

english, 2013

38

MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin

Cecchin, E, Perrone, G, Nobili, S, Polesel, J, De Mattia, E, Zanusso, C, Petreni, P, Lonardi, S, Pella, N, D'Andrea, M, Errante, D, Rizzolio, F, Mazzei, T, Landini, I, Mini, E, Toffoli, G

Journal:

The Pharmacogenomics Journal

Year:

2015

Language:

english

File:

PDF, 617 KB

english, 2015

39

Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model

Paterni, Ilaria, Bertini, Simone, Granchi, Carlotta, Tuccinardi, Tiziano, Macchia, Marco, Martinelli, Adriano, Caligiuri, Isabella, Toffoli, Giuseppe, Rizzolio, Flavio, Carlson, Kathryn E., Katzenelle

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.28 MB

english, 2015

40

JNJ-26070109 [(R)4-Bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide]: A Novel, Potent, and Selective Cholecystokinin 2 Receptor Antagonist with Good Oral Bioavailability

Morton, M. F., Barrett, T. D., Freedman, J., Li, L., Rizzolio, M. C., Prendergast, C. E., Wu, X., Moreno, V., Pyati, J., Figueroa, K., Cagnon, L., Lagaud, G., Ver Donck, L., Ghoos, E., Allison, B., Ra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

41

Epigenetic analysis of the critical region I for premature ovarian failure: demonstration of a highly heterochromatic domain on the long arm of the mammalian X chromosome

Rizzolio, F, Pramparo, T, Sala, C, Zuffardi, O, De Santis, L, Rabellotti, E, Calzi, F, Fusi, F, Bellazzi, R, Toniolo, D

Journal:

Journal of Medical Genetics

Year:

2009

Language:

english

File:

PDF, 629 KB

english, 2009

42

Neuropilin-1-Dependent Regulation of EGF-Receptor Signaling

Rizzolio, S., Rabinowicz, N., Rainero, E., Lanzetti, L., Serini, G., Norman, J., Neufeld, G., Tamagnone, L.

Journal:

Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

43

Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells

Ciarcia, Roberto, Damiano, Sara, Montagnaro, Serena, Pagnini, Ugo, Ruocco, Antonio, Caparrotti, Giuseppe, d'Angelo, Danila, Boffo, Silvia, Morales, Fátima, Rizzolio, Flavio, Florio, Salvatore, Giordan

Journal:

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

44

Characterization of a Robust Enzymatic Assay for Inhibitors of 2-Oxoglutarate-Dependent Hydroxylases

Kanelakis, K. C., Palomino, H. L., Li, L., Wu, J., Yan, W., Rosen, M. D., Rizzolio, M. C., Trivedi, M., Morton, M. F., Yang, Y., Venkatesan, H., Rabinowitz, M. H., Shankley, N. P., Barrett, T. D.

Journal:

Journal of Biomolecular Screening

Year:

2009

Language:

english

File:

PDF, 537 KB

english, 2009

45

3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a Novel, Potent, and Selective Cholecystokinin 1 Receptor Antagonist: In Vitro and in Vivo Pharmacological Comparison with Dexloxiglumide

Morton, M. F., Barrett, T. D., Yan, W., Freedman, J. M., Lagaud, G., Prendergast, C. E., Moreno, V., Pyati, J., Figueroa, K., Li, L., Wu, X., Rizzolio, M., Breitenbucher, J. G., McClure, K., Shankley,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2007

Language:

english

File:

PDF, 339 KB

english, 2007

46

Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1

Rizzolio, F, Lucchetti, C, Caligiuri, I, Marchesi, I, Caputo, M, Klein-Szanto, A J, Bagella, L, Castronovo, M, Giordano, A

Journal:

Cell Death & Differentiation

Year:

2012

Language:

english

File:

PDF, 673 KB

english, 2012

47

Clinical Predictive Circulating Peptides in Rectal Cancer Patients Treated with Neoadjuvant Chemoradiotherapy

Crotti, Sara, Enzo, Maria Vittoria, Bedin, Chiara, Pucciarelli, Salvatore, Maretto, Isacco, Del Bianco, Paola, Traldi, Pietro, Tasciotti, Ennio, Ferrari, Mauro, Rizzolio, Flavio, Toffoli, Giuseppe, Gi

Journal:

Journal of Cellular Physiology

Year:

2015

Language:

english

File:

PDF, 298 KB

english, 2015

48

Chromosomal rearrangements in Xq and premature ovarian failure: mapping of 25 new cases and review of the literature

Journal:

Human Reproduction

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

49

Biocompatible tailored zirconia mesoporous nanoparticles with high surface area for theranostic applications

Sponchia, Gabriele, Ambrosi, Emmanuele, Rizzolio, Flavio, Hadla, Mohamad, Tedesco, Anna Del, Spena, Concetta Russo, Toffoli, Giuseppe, Riello, Pietro, Benedetti, Alvise

Journal:

Journal of Materials Chemistry B

Year:

2015

Language:

english

File:

PDF, 2.45 MB

english, 2015

50

4-Aryliden-2-methyloxazol-5(4 H )-one as a new scaffold for selective reversible MAGL inhibitors

Granchi, Carlotta, Rizzolio, Flavio, Bordoni, Vittorio, Caligiuri, Isabella, Manera, Clementina, Macchia, Marco, Minutolo, Filippo, Martinelli, Adriano, Giordano, Antonio, Tuccinardi, Tiziano

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 749 KB

english, 2015

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