Roberta Brinton: search on Z-Library

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101

P3-202

Wang, Jun Ming, Irwin, Ronald, Brinton, Roberta D.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 63 KB

english, 2006

102

Estrogen receptor-β regulation of insulin signaling and energy metabolism in APOE- ε2, ε3, ε4 brains

Mao, Zisu, Brinton, Roberta, Schneider, Lon, Zhao, Liqin

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 49 KB

english, 2013

103

Allopregnanolone as a regenerative therapeutic for Alzheimer's: Formulation development for clinical trials

Irwin, Ronald, Chen, Shuhua, Zhu, Muye, Hernandez, Eric, Rodgers, Kathleen, Wang, Junming, Bolger, Michael, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 52 KB

english, 2012

104

Preclinical efficacy of 2-Deoxyglucose to sustain mitochondrial metabolic function and delay progression of Alzheimer's pathology

Yao, Jia, Chen, Shuhua, Irwin, Ronald, Mao, Zisu, Cadenas, Enrique, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 73 KB

english, 2011

105

Activation of estrogen receptor beta promotes IRS/PI3K/AKT/GSK3B-mediated insulin signaling in the female brain: Implications for anti-aging and Alzheimer's prevention

Zhao, Liqin, Mao, Zisu, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

106

Motor deficits in mouse models of Alzheimer's disease

Adeosun, Samuel, Hou, Xu, Zheng, Baoying, Paul, Ian, Irwin, Ronald, Brinton, Roberta, Wang, Junming

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

107

Neuromodulation: Associative and nonlinear adaptation

Brinton, Roberta E.

Journal:

Brain Research Bulletin

Year:

1990

Language:

english

File:

PDF, 1.06 MB

english, 1990

108

P4-414

Zhao, Liqin, Brinton, Roberta Diaz

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

109

Window of opportunity for estrogen and progestin intervention in brain aging and Alzheimer's disease

Singh, Meharvan, Simpkins, James W., Bimonte-Nelson, Heather A., Brinton, Roberta Diaz

Journal:

Year:

2013

Language:

english

File:

PDF, 223 KB

english, 2013

110

Allopregnanolone as a regenerative therapeutic for Alzheimer's disease, 2: Bridging subcutaneous to intravenous formulations for clinical trials

Irwin, Ronald, Chen, Shuhua, To, Jimmy, Zhu, Muye, Yao, Jia, Rodgers, Kathleen, Bolger, Michael, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 255 KB

english, 2013

111

A bioenergetic trajectory of female brain aging and Alzheimer's disease 2: Mechanistic link between mitochondrial dysfunction and white matter degeneration in the normal mammalian aging female brain

Klosinski, Lauren, Yao, Jia, Chen, Shuhua, Mao, Zisu, Zhao, Liqin, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

112

Allopregnanolone analogues promote proliferation of neural progenitor cells

Chen, Shuhua, Tusty, Mahbuba, Johnstone, Timothy, Hogenkamp, Derk, Gee, Kelvin, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 47 KB

english, 2012

113

Allopregnanolone promotes neurogenesis, restores cognitive function and reduces Alzheimer's pathology in adult triple transgenic Alzheimer's mice: Preclinical development and formulation

Irwin, Ronald W., Singh, Chanpreet, Liu, Lifei, Wang, Junming, Yao, Jia, Chen, Shuhua, Henry, Sherry, Thompson, Richard F., Brinton, Roberta D.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

114

A bioenergetic trajectory of female brain aging and Alzheimer's disease 3: Development of metabolic and physiological biomarker profiles for early detection of women at risk for Alzheimer's disease

Rettberg, Jamaica, Mack, Wendy, Hodis, Howard, Dang, Ha, Zhao, Liqin, Schneider, Lon, Stanczyk, Frank, Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 70 KB

english, 2013

115

Allopregnanolone as a regenerative therapeutic for Alzheimer's disease, 1: From discovery to phase I multiple-ascending-dose clinical trial

Brinton, Roberta, Irwin, Ronald, Mack, Wendy, Rodgers, Kathleen, Bauer, Gerhard, Rogawski, Michael, Schneider, Lon

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 52 KB

english, 2013

116

P4-350

Brinton, Roberta D., Wang, Jun Ming, Irwin, Ronald, Liu, Lifei, Chen, Shuhua, Wu, Tzu-wei

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

117

Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer’s disease and the effect of lipoic acid: a 13C-NMR study

Sancheti, Harsh, Patil, Ishan, Kanamori, Keiko, Díaz Brinton, Roberta, Zhang, Wei, Lin, Ai-Ling, Cadenas, Enrique

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2014

Language:

english

File:

PDF, 2.64 MB

english, 2014

118

Design, Synthesis, and Estrogenic Activity of a Novel Estrogen Receptor ModulatorA Hybrid Structure of 17β-Estradiol and Vitamin E in Hippocampal Neurons

Zhao, Liqin, Jin, Chunyang, Mao, Zisu, Gopinathan, Madathil B., Rehder, Kenneth, Brinton, Roberta D.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 368 KB

english, 2007

119

Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer’s disease: a 13C NMR study

Sancheti, Harsh, Kanamori, Keiko, Patil, Ishan, Díaz Brinton, Roberta, Ross, Brian D, Cadenas, Enrique

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2014

Language:

english

File:

PDF, 541 KB

english, 2014

120

Structure-Based Virtual Screening for Plant-Based ERβ-Selective Ligands as Potential Preventative Therapy against Age-Related Neurodegenerative Diseases

Zhao, Liqin, Brinton, Roberta D.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

121

Minireview: Translational Animal Models of Human Menopause: Challenges and Emerging Opportunities

Diaz Brinton, Roberta

Journal:

Year:

2012

Language:

english

File:

PDF, 90 KB

english, 2012

122

Medroxyprogesterone acetate exacerbates glutamate excitotoxicity

Nilsen, Jon, Morales, Alison, Brinton, Roberta Diaz

Journal:

Gynecological Endocrinology

Year:

2006

Language:

english

File:

PDF, 391 KB

english, 2006

123

Targeting the Prodromal Stage of Alzheimer’s Disease: Bioenergetic and Mitochondrial Opportunities

Caldwell, Charles C., Yao, Jia, Brinton, Roberta Diaz

Journal:

Neurotherapeutics

Year:

2015

Language:

english

File:

PDF, 747 KB

english, 2015

124

Association of Endogenous Sex Hormones with Adipokines and Ghrelin in Postmenopausal Women

Karim, Roksana, Stanczyk, Frank Z., Brinton, Roberta D., Rettberg, Jamaica, Hodis, Howard N., Mack, Wendy J.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 195 KB

english, 2015

125

WHI and WHIMS follow-up and human studies of soy isoflavones on cognition

Zhao, Liqin, Brinton, Roberta Diaz

Journal:

Expert Review of Neurotherapeutics

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

126

The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity

Yin, Fei, Yao, Jia, Sancheti, Harsh, Feng, Tao, Melcangi, Roberto C., Morgan, Todd E., Finch, Caleb E., Pike, Christian J., Mack, Wendy J., Cadenas, Enrique, Brinton, Roberta D.

Journal:

Neurobiology of Aging

Year:

2015

Language:

english

File:

PDF, 3.60 MB

english, 2015

127

Medroxyprogesterone Acetate Antagonizes Estrogen Up-Regulation of Brain Mitochondrial Function

Irwin, Ronald W., Yao, Jia, Ahmed, Syeda S., Hamilton, Ryan T., Cadenas, Enrique, Brinton, Roberta Diaz

Journal:

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

128

Progesterone Increases Rat Neural Progenitor Cell Cycle Gene Expression and Proliferation Via Extracellularly Regulated Kinase and Progesterone Receptor Membrane Components 1 and 2

Liu, Lifei, Wang, Junming, Zhao, Liqin, Nilsen, Jon, McClure, Kelsey, Wong, Karren, Brinton, Roberta Diaz

Journal:

Year:

2009

Language:

english

File:

PDF, 498 KB

english, 2009

129

Preclinical Analyses of the Therapeutic Potential of Allopregnanolone to Promote Neurogenesis In Vitro and In Vivo in Transgenic Mouse Model of Alzheimers Disease

Brinton, Roberta, Wang, Jun

Journal:

Current Alzheimer Research

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

130

Therapeutic Potential of Neurogenesis for Prevention and Recovery from Alzheimers Disease: Allopregnanolone as a Proof of Concept Neurogenic Agent

Diaz Brinton, Roberta, Ming Wang, Jun

Journal:

Current Alzheimer Research

Year:

2006

Language:

english

File:

PDF, 46 KB

english, 2006

131

Clinically Relevant Progestins Regulate Neurogenic and Neuroprotective Responses in Vitro and in Vivo

Liu, Lifei, Zhao, Liqin, She, Hongyun, Chen, Shuhua, Wang, Jun Ming, Wong, Charisse, McClure, Kelsey, Sitruk-Ware, Regine, Brinton, Roberta Diaz

Journal:

Year:

2010

Language:

english

File:

PDF, 599 KB

english, 2010

132

Differential Responses of Progesterone Receptor Membrane Component-1 ( Pgrmc1 ) and the Classical Progesterone Receptor ( Pgr ) to 17β-Estradiol and Progesterone in Hippocampal Subregions that Support Synaptic Remodeling and Neurogenesis

Bali, Namrata, Arimoto, Jason M., Iwata, Nahoko, Lin, Sharon W., Zhao, Liqin, Brinton, Roberta D., Morgan, Todd E., Finch, Caleb E.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

133

A Select Combination of Clinically Relevant Phytoestrogens Enhances Estrogen Receptor β-Binding Selectivity and Neuroprotective Activities in Vitro and in Vivo

Zhao, Liqin, Mao, Zisu, Brinton, Roberta Diaz

Journal:

Year:

2009

Language:

english

File:

PDF, 343 KB

english, 2009

134

Allopregnanolone Increases the Number of Dopaminergic Neurons in Substantia Nigra of a Triple Transgenic Mouse Model of Alzheimer’s Disease

Sun, Chenyou, Ou, Xiaoming, Farley, Jerry M., Stockmeier, Craig, Bigler, Steven, Diaz Brinton, Roberta, Wang, Jun Ming

Journal:

Current Alzheimer Research

Year:

2012

Language:

english

File:

PDF, 578 KB

english, 2012

135

Dose and Temporal Pattern of Estrogen Exposure Determines Neuroprotective Outcome in Hippocampal Neurons: Therapeutic Implications

Chen, Shuhua, Nilsen, Jon, Brinton, Roberta Diaz

Journal:

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

136

Estradiol-17β-Induced Human Neural Progenitor Cell Proliferation Is Mediated by an Estrogen Receptor β-Phosphorylated Extracellularly Regulated Kinase Pathway

Wang, Jun Ming, Liu, Lifei, Brinton, Roberta Diaz

Journal:

Year:

2008

Language:

english

File:

PDF, 643 KB

english, 2008

137

Impact of Progestins on Estrogen-Induced Neuroprotection: Synergy by Progesterone and 19-Norprogesterone and Antagonism by Medroxyprogesterone Acetate

Nilsen, Jon, Brinton, Roberta Diaz

Journal:

Year:

2002

Language:

english

File:

PDF, 385 KB

english, 2002

138

Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

Jun Ming Wang, Chanpreet Singh, Lifei Liu, Ronald W. Irwin, Shuhua Chen, Eun Ji Chung, Richard F. Thompson and Roberta Diaz Brinton

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.53 MB

english, 2010

139

Allopregnanolone chronic exposure using regenerative treatment regimen: Preclinical ind enabling toxicology indicating safety

Irwin, Ronald W., Kim, Kyuri, Green, Carol E., Solinsky, Christine M., Bauer, Gerhard, Rogawski, Michael A., Rodgers, Kathleen E., Brinton, Roberta Diaz

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 63 KB

english, 2015

140

Interactions of diabetes and postmenopausal hormone therapy on brain volumes: Whims

Hugenschmidt, Christina E., Resnick, Susan M., Diaz-Brinton, Roberta, Manson, JoAnn E., Yaffe, Kristine, Vaughan, A. Leslie, Craft, Suzanne, Edwards, Beatrice J., Casanova, Ramon, Masaki, Kamal, Espel

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 265 KB

english, 2015

141

Early-stage development of ips-based biomarkers to identify patient population with a regenerative profile responsive to allopregnanolone

Solinsky, Christine M., Desai, Maunil K., Yao, Jia, Hennes, Valerie, Chang Chui, Helena, Ichida, Justin K., Diaz-Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 68 KB

english, 2015

142

White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease

Klosinski, Lauren P., Yao, Jia, Yin, Fei, Fonteh, Alfred N., Harrington, Michael G., Christensen, Trace A., Trushina, Eugenia, Brinton, Roberta Diaz

Journal:

Year:

2015

Language:

english

File:

PDF, 3.72 MB

english, 2015

143

Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype

Rettberg, Jamaica R., Dang, Ha, Hodis, Howard N., Henderson, Victor W., St. John, Jan A., Mack, Wendy J., Brinton, Roberta Diaz

Journal:

Neurobiology of Aging

Year:

2016

Language:

english

File:

PDF, 596 KB

english, 2016

144

Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease

Zhao, Liqin, Mao, Zisu, Woody, Sarah K., Brinton, Roberta D.

Journal:

Neurobiology of Aging

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

145

Aging transition of perimenopause is associated with bioenergetic shift in the female brain and decline in long-term potentiation

Yin, Fei, Yao, Jia, Sancheti, Harsh, Feng, Tao, Mack, Wendy J., Cadenas, Enrique, Diaz-Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 68 KB

english, 2015

146

Interactions of diabetes and postmenopausal hormone therapy on brain volumes: Whims

Hugenschmidt, Christina E., Resnick, Susan M., Diaz-Brinton, Roberta, Manson, JoAnn E., Yaffe, Kristine, Vaughan, A. Leslie, Craft, Suzanne, Edwards, Beatrice J., Casanova, Ramon, Masaki, Kamal, Espel

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 115 KB

english, 2015

147

Impact of progestins on estradiol potentiation of the glutamate calcium response

Nilsen, Jon, Brinton, Roberta Diaz

Journal:

Year:

2002

Language:

english

File:

PDF, 251 KB

english, 2002

148

Mechanistic pathways linking mitochondrial oxidative stress and white matter degeneration in the aging mammalian female brain

Klosinski, Lauren, Yao, Jia, Chen, Shuhua, Mao, Jennifer, Trushina, Eugenia, Tiwari-Woodruff, Seema, Diaz-Brinton, Roberta

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 49 KB

english, 2015

149

SEX DIFFERENCES IN BIOENERGETIC AGING OF THE BRAIN AND RISK OF ALZHEIMER'S DISEASE

Brinton, Roberta Diaz, Zhao, Liqin, Yin, Fei, Yao, Jia, Cadenas, Enrique

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

150

[Progress in Brain Research] Advances in Brain Vasopressin Volume 119 || Vasopressin in the mammalian brain: The neurobiology of a mnemonic peptide

Brinton, Roberta Diaz

Year:

1999

Language:

english

File:

PDF, 2.28 MB

english, 1999