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1

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

Matsumoto, Tomoya, Rauskolb, Stefanie, Polack, Martin, Klose, Johannes, Kolbeck, Roland, Korte, Martin, Barde, Yves-Alain

Journal:

Nature Neuroscience

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

2

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease

Geoffrey L. Stephens, Bonnie Swerdlow, Ebony Benjamin, Anthony J. Coyle, Alison Humbles, Roland Kolbeck, Michael Fung

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 509 KB

english, 2011

3

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Kolbeck, Roland, Kozhich, Alexander, Koike, Masamichi, Peng, Li, Andersson, Cecilia K., Damschroder, Melissa M., Reed, Jennifer L., Woods, Robert, Dall'Acqua, William W., Stephens, Geoffrey L., Erjefa

Journal:

Journal of Allergy and Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

4

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

Laviolette, Michel, Gossage, David L., Gauvreau, Gail, Leigh, Richard, Olivenstein, Ron, Katial, Rohit, Busse, William W., Wenzel, Sally, Wu, Yanping, Datta, Vivekananda, Kolbeck, Roland, Molfino, Nes

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 2.21 MB

english, 2013

5

The Role of IgE in Autoimmunity

Sanjuan, Miguel A., Sagar, Divya, Kolbeck, Roland

Journal:

Journal of Allergy and Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 859 KB

english, 2016

6

Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity

Griesbeck, Oliver, Canossa, Marco, Campana, Gabriele, G�rtner, Annette, Hoener, Marius C., Nawa, Hiroyuki, Kolbeck, Roland, Thoenen, Hans

Journal:

Microscopy Research and Technique

Year:

1999

Language:

english

File:

PDF, 356 KB

english, 1999

7

Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis

James R. Tonra, Brita S. Reiseter, Roland Kolbeck, Kumiko Nagashima, Robbie Robertson, Bruce Keyt, Ronald M. Lindsay

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 551 KB

english, 2001

8

Brain-Derived Neurotrophic Factor Levels in the Nervous System of Wild-Type and Neurotrophin Gene Mutant Mice

Roland Kolbeck, Ilse Bartke, Walter Eberle, Yves-Alain Barde

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 1021 KB

english, 1999

9

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

Schnell, Lisa, Schneider, Regula, Kolbeck, Roland, Barde, Yves-Alain, Schwab, Martin E.

Journal:

Year:

1994

File:

PDF, 526 KB

1994

10

Production and characterization of recombinant mouse neurotrophin-3

Rudolf GÖTZ, Roland KOLBECK, Friedrich LOTTSPEICH, Yves-Alain BARDE

Journal:

Year:

1992

Language:

english

File:

PDF, 518 KB

english, 1992

11

Characterisation of Neurotrophin Dimers and Monomers

Roland Kolbeck, Stefan Jungbluth, Yves-Alain Barde

Journal:

Year:

1994

Language:

english

File:

PDF, 3.39 MB

english, 1994

12

Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

Séverine Létuvé, Alexander Kozhich, Alison Humbles, Yambasu Brewah, Marie-Christine Dombret, Martine Grandsaigne, Homa Adle, Roland Kolbeck, Michel Aubier, Anthony J. Coyle, Marina Pretolani

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1015 KB

english, 2010

13

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

Henault, Jill, Martinez, Jennifer, Riggs, Jeffrey M., Tian, Jane, Mehta, Payal, Clarke, Lorraine, Sasai, Miwa, Latz, Eicke, Brinkmann, Melanie M., Iwasaki, Akiko, Coyle, Anthony J., Kolbeck, Roland, G

Journal:

Year:

2012

Language:

english

File:

PDF, 1.69 MB

english, 2012

14

Distinct roles of the complement C5a receptors C5aR and C5L2 in bacterial and bacterial component-induced inflammation in human whole blood

Ling-Ling An, Roland Kolbeck, Michael Fung

Journal:

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

15

Development of an anti-C5/C5a antibody therapeutic that inhibits inflammatory responses via C5aR and C5L2 while maintaining MAC-dependent bactericidal functions

Ling-Ling An, Caroline Colley, Claire Dobson, Joanne Brennan, Kaiyong Yang, Jingying Zha, Paul Warrener, Bret Sellman, Roland Kolbeck, Michael Fung

Journal:

Year:

2012

Language:

english

File:

PDF, 69 KB

english, 2012

16

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

Busse, William W., Katial, Rohit, Gossage, David, Sari, Suha, Wang, Bing, Kolbeck, Roland, Coyle, Anthony J., Koike, Masamichi, Spitalny, George L., Kiener, Peter A., Geba, Gregory P., Molfino, Nestor

Journal:

Journal of Allergy and Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 530 KB

english, 2010

17

IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis

Wilson, Todd M., Maric, Irina, Shukla, Juhi, Brown, Margaret, Santos, Carlo, Simakova, Olga, Khoury, Paneez, Fay, Michael P., Kozhich, Alexander, Kolbeck, Roland, Metcalfe, Dean D., Klion, Amy D.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 596 KB

english, 2011

18

Novel targeted therapies for eosinophilic disorders

Wechsler, Michael E., Fulkerson, Patricia C., Bochner, Bruce S., Gauvreau, Gail M., Gleich, Gerald J., Henkel, Tim, Kolbeck, Roland, Mathur, Sameer K., Ortega, Hector, Patel, Jatin, Prussin, Calman, R

Journal:

Journal of Allergy and Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 231 KB

english, 2012

19

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

Fernando M Botelho, Jake K Nikota, Carla MT Bauer, Mathieu C Morissette, Yoichiro Iwakura, Roland Kolbeck, Donna Finch, Alison A Humbles, Martin R Stämpfli

Journal:

Respiratory Research

Year:

2012

Language:

english

File:

PDF, 546 KB

english, 2012

20

Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands

Stephens, Geoffrey L., Wang, Qun, Swerdlow, Bonnie, Bhat, Geetha, Kolbeck, Roland, Fung, Michael

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 927 KB

english, 2013

21

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B36. AIRWAY IMMUNE MECHANISMS AND INFLAMMATION: ANIMAL MODELS - The Epithelial-Derived Signals TSLP, IL-25 And IL-33 Converge On OX40L To Elicit House Dust Mite-Induced Allergic Airway Inflammation In Mice

Llop-Guevara, Alba, Chu, Derek K., In, Tracy S., Moore, Cheryl Lynn, Boudreau, Jeanette, Walker, Tina D., Goncharova, Susanna, Comeau, Michael, Budelsky, Alison, Kolbeck, Roland, Humbles, Alison A., J

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

22

In England Now

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Year:

1952

Language:

english

File:

PDF, 401 KB

english, 1952

23

Residents and fellows in radiology Annual Memorial Award competition

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Academic Radiology

Year:

1998

Language:

english

File:

PDF, 1.20 MB

english, 1998

24

Microbiota Regulates Eosinophils In The Small Intestine

Jimenez-Saiz, Rodrigo, Walker-Fattouh, Tina, Gordon, Melissa E., Ahmed, Waleed S., Dale, Breanne, Mandur, Talveer S., Kong, Joshua, Chu, Derek K., Kolbeck, Roland, Humbles, Alison A., Verdu, Elena F.,

Journal:

Journal of Allergy and Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 42 KB

english, 2014

25

Noncanonical autophagy: one small step for LC3, one giant leap for immunity

Mehta, Payal, Henault, Jill, Kolbeck, Roland, Sanjuan, Miguel A

Journal:

Current Opinion in Immunology

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

26

Neurotrophin Release by Neurotrophins: Implications for Activity-Dependent Neuronal Plasticity

Marco Canossa, Oliver Griesbeck, Benedikt Berninger, Gabriele Campana, Roland Kolbeck and Hans Thoenen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.53 MB

english, 1997

27

Neurotrophin-3 Induced by Tri-Iodothyronine in Cerebellar Granule Cells Promotes Purkinje Cell Differentiation

Dan Lindholm, Eero Castrén, Pantelis Tsoulfas, Roland Kolbeck, Maria da Penha Berzaghi, Axel Leingärtner, Carl-Philipp Heisenberg, Lino Tesarollo, Luis F. Parada and Hans Thoenen

Journal:

The Journal of Cell Biology

Year:

1993

Language:

english

File:

PDF, 2.75 MB

english, 1993

28

Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure

Morissette, Mathieu C, Jobse, Brian N, Thayaparan, Danya, Nikota, Jake K, Shen, Pamela, Labiris, Nancy, Kolbeck, Roland, Nair, Parameswaran, Humbles, Alison A, Stämpfli, Martin R

Journal:

Respiratory Research

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

29

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C22. ASTHMA THERAPY - Depletion Of Airway Eosinophils By Benralizumab An Anti-IL5 Receptor Alpha Monoclonal Antibody

Gossage, David L., Laviolette, Michel, Gauvreau, Gail M., Leigh, Richard, Kolbeck, Roland, Wu, Yanping, Richman, Laura, Molfino, Nestor A.

Year:

2012

Language:

english

File:

PDF, 25 KB

english, 2012

30

Stiffness Characteristics of Composite Hybrid External Fixators

Windhagen, Henning, Gl??ckner, Roland, Bail, Hermann, Kolbeck, Stefan, Raschke, Michael

Journal:

Clinical Orthopaedics and Related Research®

Year:

2002

Language:

english

File:

PDF, 608 KB

english, 2002

31

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A32. SMOKE-RELATED ALTERATIONS IN LUNG BIOLOGY - Importance Of IL-1 Receptor 1 In The Autoimmune Response Elicited By Cigarette Smoke

Morissette, Mathieu C., Jobse, Brian N., Nikota, Jake K., Shen, Pamela, Kolbeck, Roland, Finch, Donna, Humbles, Alison A., Stampfli, Martin R.

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

32

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D22. PATHOGENESIS OF LUNG FIBROSIS AND AIRWAY REMODELING - MMP-12 Is A Critical Mediator Of Inflammation, IL-13 Expression And Fibrosis Following Activation Of Fas In The Airways

Kearley, Jennifer, Rebelatto, Marlon, Kolbeck, Roland, Humbles, Alison

Year:

2012

Language:

english

File:

PDF, 18 KB

english, 2012

33

MEDI-551 Treatment Effectively Depletes B Cells and Reduces Serum Titers of Autoantibodies in Mice Transgenic for Sle1 and Human CD19

Gallagher, Sandra, Yusuf, Isharat, McCaughtry, Tom M., Turman, Sean, Sun, Hong, Kolbeck, Roland, Herbst, Ronald, Wang, Yue

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 572 KB

english, 2016

34

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] A32. SMOKE-RELATED ALTERATIONS IN LUNG BIOLOGY - CXCR2 Ligands Drive Exacerbated Cellular Inflammation In A Bacterial Exacerbation Model Of Cigarette Smoke-Induced Inflammation

Nikota, Jake K., Shen, Pamela, Morissette, Mathieu, Bauer, Carla, Lambert, Kristen, Kolbeck, Roland, Finch, Donna, Humbles, Alison A., Stampfli, Martin R.

Year:

2012

Language:

english

File:

PDF, 17 KB

english, 2012

35

Complement C5a potentiates uric acid crystal-induced IL-1β production

An, Ling-Ling, Mehta, Payal, Xu, Linda, Turman, Sean, Reimer, Thornik, Naiman, Brian, Connor, Jane, Sanjuan, Miguel, Kolbeck, Roland, Fung, Michael

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 989 KB

english, 2014

36

Monoclonal Antibody Therapy for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease with Eosinophilic Inflammation

Nixon, John, Newbold, Paul, Mustelin, Tomas, Anderson, Gary P., Kolbeck, Roland

Journal:

Pharmacology & Therapeutics

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

37

Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways

An, Ling-Ling, Gorman, Jacob V., Stephens, Geoffrey, Swerdlow, Bonnie, Warrener, Paul, Bonnell, Jessica, Mustelin, Tomas, Fung, Michael, Kolbeck, Roland

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 751 KB

english, 2016

38

Plasmacytoid dendritic cells in autoimmunity

Panda, Santosh K, Kolbeck, Roland, Sanjuan, Miguel A

Journal:

Current Opinion in Immunology

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

39

Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

Ettinger, Rachel, Karnell, Jodi L., Henault, Jill, Panda, Santosh K., Riggs, Jeffrey M., Kolbeck, Roland, Sanjuan, Miguel A.

Journal:

Year:

2017

Language:

english

File:

PDF, 4.62 MB

english, 2017

40

IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression

Wang, Yaya, Mumm, John Brian, Herbst, Ronald, Kolbeck, Roland, Wang, Yue

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

41

Relative Contribution of Endogenous Neurotrophins in Hippocampal Long-Term Potentiation

Chen, Guiquan, Kolbeck, Roland, Barde, Yves-Alain, Bonhoeffer, Tobias, Kossel, Albrecht

Journal:

Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

42

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

Panda, Santosh K., Facchinetti, Valeria, Voynova, Elisaveta, Hanabuchi, Shino, Karnell, Jodi L., Hanna, Richard N., Kolbeck, Roland, Sanjuan, Miguel A., Ettinger, Rachel, Liu, Yong-Jun

Journal:

The Journal of clinical investigation

Year:

2018

Language:

english

File:

PDF, 10.70 MB

english, 2018

43

Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

Sawai, Catherine M., Serpas, Lee, Neto, Antonio Galvao, Jang, Geunhyo, Rashidfarrokhi, Ali, Kolbeck, Roland, Sanjuan, Miguel A., Reizis, Boris, Sisirak, Vanja

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 14.81 MB

english, 2018

44

Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

Karnell, Jodi L., Rieder, Sadiye Amcaoglu, Ettinger, Rachel, Kolbeck, Roland

Journal:

Advanced Drug Delivery Reviews

Year:

2018

Language:

english

File:

PDF, 5.85 MB

english, 2018

45

Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus

Rahman, Saifur, Sagar, Divya, Hanna, Richard N, Lightfoot, Yaima L, Mistry, Pragnesh, Smith, Carolyne K, Manna, Zerai, Hasni, Sarfaraz, Siegel, Richard M, Sanjuan, Miguel A, Kolbeck, Roland, Kaplan, M

Journal:

Annals of the Rheumatic Diseases

Year:

2019

Language:

english

File:

PDF, 2.49 MB

english, 2019

46

Evaluation of ultra-low input RNA sequencing for the study of human T cell transcriptome

Wang, Jingya, Rieder, Sadiye Amcaoglu, Wu, Jincheng, Hayes, Susana, Halpin, Rebecca A., de los Reyes, Melissa, Shrestha, Yashaswi, Kolbeck, Roland, Raja, Rajiv

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 5.92 MB

english, 2019

47

SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus

Smith, Michael A., Henault, Jill, Karnell, Jodi L., Parker, Melissa L., Riggs, Jeffrey M., Sinibaldi, Dominic, Taylor, Devon K., Ettinger, Rachel, Grant, Ethan P., Sanjuan, Miguel A., Kolbeck, Roland,

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

48

B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

Rieder, Sadiye Amcaoglu, Wang, Jingya, White, Natalie, Qadri, Ariful, Menard, Catherine, Stephens, Geoffrey, Karnell, Jodi L., Rudd, Christopher E., Kolbeck, Roland

Journal:

Cellular & Molecular Immunology

Year:

2020

Language:

english

File:

PDF, 1.26 MB

english, 2020

49

Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

Jogdand, Prajakta, Siddhuraj, Premkumar, Mori, Michiko, Sanden, Caroline, JÃ¶nsson, Jimmie, Walls, Andrew F., Kearley, Jennifer, Humbles, Alison A., Kolbeck, Roland, Bjermer, Leif, Newbold, Paul, Erje

Journal:

European Respiratory Journal

Year:

2020

File:

PDF, 3.35 MB

2020

50

Acute activation of bronchopulmonary vagal nociceptors by type I interferons

Patil, Mayur J., Ru, Fei, Sun, Hui, Wang, Jingya, Kolbeck, Roland R., Dong, Xinzhong, Kollarik, Marian, Canning, Brendan J., Undem, Bradley J.

Journal:

The Journal of Physiology

Year:

2020

File:

PDF, 1.64 MB

2020