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51

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

Zheng, Ye, Chaudhry, Ashutosh, Kas, Arnold, deRoos, Paul, Kim, Jeong M., Chu, Tin-Tin, Corcoran, Lynn, Treuting, Piper, Klein, Ulf, Rudensky, Alexander Y.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

52

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Zheng, Ye, Josefowicz, Steven, Chaudhry, Ashutosh, Peng, Xiao P., Forbush, Katherine, Rudensky, Alexander Y.

Journal:

Year:

2010

Language:

english

File:

PDF, 581 KB

english, 2010

53

Intraclonal competition limits the fate determination of regulatory T cells in the thymus

Bautista, Jhoanne L, Lio, Chan-Wang J, Lathrop, Stephanie K, Forbush, Katherine, Liang, Yuqiong, Luo, Jingqin, Rudensky, Alexander Y, Hsieh, Chyi-Song

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 934 KB

english, 2009

54

Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells

Rudra, Dipayan, Egawa, Takeshi, Chong, Mark M W, Treuting, Piper, Littman, Dan R, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

55

Dual TCR T cells: gaining entry into the periphery

Gavin, Marc A., Rudensky, Alexander Y.

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 49 KB

english, 2002

56

Erratum: A function for interleukin 2 in Foxp3-expressing regulatory T cells

Fontenot, Jason D, Rasmussen, Jeffrey P, Gavin, Marc A, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2006

Language:

english

File:

PDF, 45 KB

english, 2006

57

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

Fontenot, Jason D, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2005

Language:

english

File:

PDF, 354 KB

english, 2005

58

A function for interleukin 2 in Foxp3-expressing regulatory T cells

Fontenot, Jason D, Rasmussen, Jeffrey P, Gavin, Marc A, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2005

Language:

english

File:

PDF, 868 KB

english, 2005

59

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

Hsieh, Chyi-Song, Zheng, Ye, Liang, Yuqiong, Fontenot, Jason D, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2006

Language:

english

File:

PDF, 310 KB

english, 2006

60

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Kim, Jeong M, Rasmussen, Jeffrey P, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2006

Language:

english

File:

PDF, 680 KB

english, 2006

61

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

Williams, Luke M, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 612 KB

english, 2007

62

Foxp3 in control of the regulatory T cell lineage

Zheng, Ye, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 450 KB

english, 2007

63

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3− precursor cells in the absence of interleukin 10

Maynard, Craig L, Harrington, Laurie E, Janowski, Karen M, Oliver, James R, Zindl, Carlene L, Rudensky, Alexander Y, Weaver, Casey T

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 759 KB

english, 2007

64

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

Gavin, Marc A., Clarke, Sally R., Negrou, Ella, Gallegos, Alena, Rudensky, Alexander

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 439 KB

english, 2001

65

Thymocyte expression of cathepsin L is essential for NKT cell development

Honey, Karen, Benlagha, Kamel, Beers, Courtney, Forbush, Katherine, Teyton, Luc, Kleijmeer, Monique J., Rudensky, Alexander Y., Bendelac, Albert

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 684 KB

english, 2002

66

TGFβ signalling in control of T-cell-mediated self-reactivity

Rubtsov, Yuri P, Rudensky, Alexander Y

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 587 KB

english, 2007

67

Su.135. Regulatory T-Cell Expression of CCR4 is Required to Prevent Cutaneous & Pulmonary Inflammation

Blythe D. Sather, Dora Gyarmati, Mike Miazgowicz, Jason D. Fontenot, Alexander Y. Rudensky, Daniel J. Campbell

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 37 KB

english, 2006

68

Endogenous peptides associated with MHC class II and selection of CD4 T cells

Alexander Y. Rudensky

Journal:

Seminars in Immunology

Year:

1995

Language:

english

File:

PDF, 110 KB

english, 1995

69

Evaluating peptide repertoires within the context of thymocyte development

Gregory M. Barton, Alexander Y. Rudensky

Journal:

Seminars in Immunology

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

70

FOXP3 and NFAT: Partners in Tolerance

Alexander Y. Rudensky, Marc Gavin, Ye Zheng

Journal:

Year:

2006

Language:

english

File:

PDF, 309 KB

english, 2006

71

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

Dan R. Littman, Alexander Y. Rudensky

Journal:

Year:

2010

Language:

english

File:

PDF, 648 KB

english, 2010

72

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

Li-Fan Lu, Mark P. Boldin, Ashutosh Chaudhry, Ling-Li Lin, Konstantin D. Taganov, Toshikatsu Hanada, Akihiko Yoshimura, David Baltimore, Alexander Y. Rudensky

Journal:

Year:

2010

Language:

english

File:

PDF, 2.52 MB

english, 2010

73

Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict

Robert M. Samstein, Steven Z. Josefowicz, Aaron Arvey, Piper M. Treuting, Alexander Y. Rudensky

Journal:

Year:

2012

Language:

english

File:

PDF, 961 KB

english, 2012

74

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Jason D. Fontenot, Jeffrey P. Rasmussen, Luke M. Williams, James L. Dooley, Andrew G. Farr, Alexander Y. Rudensky

Journal:

Year:

2005

Language:

english

File:

PDF, 957 KB

english, 2005

75

Cellular Mechanisms of Fatal Early-Onset Autoimmunity in Mice with the T Cell-Specific Targeting of Transforming Growth Factor-β Receptor

Julien C. Marie, Denny Liggitt, Alexander Y. Rudensky

Journal:

Year:

2006

Language:

english

File:

PDF, 1.09 MB

english, 2006

76

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

Yuri P. Rubtsov, Jeffrey P. Rasmussen, Emil Y. Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R. Henderson Jr., Werner Muller, Alexander Y. Rudensky

Journal:

Year:

2008

Language:

english

File:

PDF, 2.43 MB

english, 2008

77

An N-Terminal Mutation of the Foxp3 Transcription Factor Alleviates Arthritis but Exacerbates Diabetes

Jaime Darce, Dipayan Rudra, Li Li, Junko Nishio, Daniela Cipolletta, Alexander Y. Rudensky, Diane Mathis, Christophe Benoist

Journal:

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012

78

Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse

Lianne C. Hsing, Elizabeth A. Kirk, Timothy S. McMillen, Shuo-Hung Hsiao, Mark Caldwell, Barbara Houston, Alexander Y. Rudensky, Renee C. LeBoeuf

Journal:

Journal of Autoimmunity

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

79

Methylation of a Histone Mimic within the Histone Methyltransferase G9a Regulates Protein Complex Assembly

Srihari C. Sampath, Ivan Marazzi, Kyoko L. Yap, Srinath C. Sampath, Andrew N. Krutchinsky, Ingrid Mecklenbräuker, Agnes Viale, Eugene Rudensky, Ming-Ming Zhou, Brian T. Chait, Alexander Tarakhovsky

Journal:

Year:

2007

Language:

english

File:

PDF, 1.65 MB

english, 2007

80

Crystal Structure Of MHC Class II I-Ab in Complex with a Human CLIP Peptide: Prediction of an I-Ab Peptide-binding Motif

Yuerong Zhu, Alexander Y. Rudensky, Adam L. Corper, Luc Teyton, Ian A. Wilson

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.97 MB

english, 2003

81

Altered Antigen Presentation in Mice Lacking H2-O

Monika Liljedahl, Ola Winqvist, Charles D Surh, Phillip Wong, Karen Ngo, Luc Teyton, Per A Peterson, Anders Brunmark, Alexander Y Rudensky, Wai-Ping Fung-Leung, Lars Karlsson

Journal:

Year:

1998

Language:

english

File:

PDF, 303 KB

english, 1998

82

Deficient Positive Selection of CD4 T Cells in Mice Displaying Altered Repertoires of MHC Class II–Bound Self-Peptides

Catherine E Grubin, Susan Kovats, Paul deRoos, Alexander Y Rudensky

Journal:

Year:

1997

Language:

english

File:

PDF, 272 KB

english, 1997

83

Distinct Dendritic Cell Populations Sequentially Present Antigen to CD4 T Cells and Stimulate Different Aspects of Cell-Mediated Immunity

Andrea A Itano, Stephen J McSorley, R.Lee Reinhardt, Benjamin D Ehst, Elizabeth Ingulli, Alexander Y Rudensky, Marc K Jenkins

Journal:

Year:

2003

Language:

english

File:

PDF, 614 KB

english, 2003

84

A goodbye to Charlie Janeway: Charles A. Janeway Jr (1943–2003)

Alexander (Sasha I) Rudensky, Alexander (Sasha II) Chervonsky

Journal:

Trends in Immunology

Year:

2003

Language:

english

File:

PDF, 120 KB

english, 2003

85

Novel Foxo1-dependent transcriptional programs control Treg cell function

Ouyang, Weiming, Liao, Will, Luo, Chong T., Yin, Na, Huse, Morgan, Kim, Myoungjoo V., Peng, Min, Chan, Pamela, Ma, Qian, Mo, Yifan, Meijer, Dies, Zhao, Keji, Rudensky, Alexander Y., Atwal, Gurinder, Z

Journal:

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

86

Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting

Loeb, Gabriel B., Khan, Aly A., Canner, David, Hiatt, Joseph B., Shendure, Jay, Darnell, Robert B., Leslie, Christina S., Rudensky, Alexander Y.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.07 MB

english, 2012

87

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Rudra, Dipayan, deRoos, Paul, Chaudhry, Ashutosh, Niec, Rachel E, Arvey, Aaron, Samstein, Robert M, Leslie, Christina, Shaffer, Scott A, Goodlett, David R, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 975 KB

english, 2012

88

The plasticity and stability of regulatory T cells

Sakaguchi, Shimon, Vignali, Dario A. A., Rudensky, Alexander Y., Niec, Rachel E., Waldmann, Herman

Journal:

Nature Reviews Immunology

Year:

2013

Language:

english

File:

PDF, 244 KB

english, 2013

89

Regulatory T cells: recommendations to simplify the nomenclature

Abbas, Abul K, Benoist, Christophe, Bluestone, Jeffrey A, Campbell, Daniel J, Ghosh, Sankar, Hori, Shohei, Jiang, Shuiping, Kuchroo, Vijay K, Mathis, Diane, Roncarolo, Maria Grazia, Rudensky, Alexande

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 110 KB

english, 2013

90

Intracellular assembly and transport of endogenous peptide-MHC class II complexes

Rudensky, Alexander Y., MariÄ, Maja, Eastman, Susan, Shoemaker, Lee, DeRoos, Paul C., Blum, Janice S.

Journal:

Year:

1994

Language:

english

File:

PDF, 3.95 MB

english, 1994

91

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

Josefowicz, Steven Z., Niec, Rachel E., Kim, Hye Young, Treuting, Piper, Chinen, Takatoshi, Zheng, Ye, Umetsu, Dale T., Rudensky, Alexander Y.

Journal:

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

92

Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

Arvey, Aaron, van der Veeken, Joris, Samstein, Robert M, Feng, Yongqiang, Stamatoyannopoulos, John A, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014

93

Truncation of the Class II β -Chain Cytoplasmic Domain Influences the Level of Class II/Invariant Chain-Derived Peptide Complexes

Stephen T. Smiley, Alexander Y. Rudensky, Laurie H. Glimcher and Michael J. Grusby

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 206 KB

english, 1996

94

Subtle Conformational Changes Induced in Major Histocompatibility Complex Class II Molecules by Binding Peptides

Alexander V. Chervonsky, Ruslan M. Medzhitov, Lisa K. Denzin, Avlin K. Barlow, Alexander Yu. Rudensky and Charles A. Janeway

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.72 MB

english, 1998

95

Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon

Ho, Bing-Ching, Yu, I-Shing, Lu, Li-Fan, Rudensky, Alexander, Chen, Hsuan-Yu, Tsai, Chang-Wu, Chang, Yih-Leong, Wu, Chen-Tu, Chang, Luan-Yin, Shih, Shin-Ru, Lin, Shu-Wha, Lee, Chun-Nan, Yang, Pan-Chyr

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.83 MB

english, 2014

96

Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments

Monique J. Kleijmeer, Stanislaw Morkowski, Janice M. Griffith, Alexander Y. Rudensky and Hans J. Geuze

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 1.96 MB

english, 1997

97

Interactions between innate and adaptive lymphocytes

Gasteiger, Georg, Rudensky, Alexander Y.

Journal:

Nature Reviews Immunology

Year:

2014

Language:

english

File:

PDF, 918 KB

english, 2014

98

Continuous requirement for the TCR in regulatory T cell function

Levine, Andrew G, Arvey, Aaron, Jin, Wei, Rudensky, Alexander Y

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

99

Rules for Peptide Presentation by MHC Class II Molecules

Janeway, Charles A., Mamula, Mark J., Rudensky, Alexander Yu.

Journal:

International Reviews Of Immunology

Year:

1993

Language:

english

File:

PDF, 922 KB

english, 1993

100

The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

Sekiya, Takashi, Kashiwagi, Ikkou, Inoue, Naoko, Morita, Rimpei, Hori, Shohei, Waldmann, Herman, Rudensky, Alexander Y., Ichinose, Hiroshi, Metzger, Daniel, Chambon, Pierre, Yoshimura, Akihiko

Journal:

Nature Communications

Year:

2011

Language:

english

File:

PDF, 1.73 MB

english, 2011