S Lovestone: search on Z-Library

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51

Eadc (European Alzheimer Disease Consortium) recommendations for future Alzheimer Disease Research in Europe

B. Winblad, G. B. Frisoni, L. Frolich, P. Johannsen, G. Johansson, P. Kehoe, S. Lovestone, M. Olde-rikkert, E. Reynish, P. J. Visser, B. Vellas

Journal:

The Journal of Nutrition, Health & Aging

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

52

Disturbance of Notch-1 and Wnt signalling proteins in neuroglial balloon cells and abnormal large neurons in focal cortical dysplasia in human cortex

D. Cotter, Mrinalini Honavar, Simon Lovestone, Lucy Raymond, Robert Kerwin, Brian Anderton, Ian Everall

Journal:

Acta Neuropathologica

Year:

1999

Language:

english

File:

PDF, 566 KB

english, 1999

53

Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer’s disease

Madhav Thambisetty, Abdul Hye, Catherine Foy, Eileen Daly, Amanda Glover, Allison Cooper, Andrew Simmons, Declan Murphy, Simon Lovestone

Journal:

Journal of Neurology

Year:

2008

Language:

english

File:

PDF, 264 KB

english, 2008

54

Early diagnosis and the clinical genetics of Alzheimer’s disease

Simon Lovestone

Journal:

Journal of Neurology

Year:

1999

Language:

english

File:

PDF, 33 KB

english, 1999

55

Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease

Denise Harold, Timothy Peirce, Valentina Moskvina, Amanda Myers, Susan Jones, Paul Hollingworth, Pamela Moore, Simon Lovestone, John Powell, Catherine Foy, Nicola Archer, Sarah Walter, Amanda Edmonson

Journal:

Year:

2003

Language:

english

File:

PDF, 211 KB

english, 2003

56

Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons

O. V. Forlenza, J. M. Spink, R. Dayanandan, B. H. Anderton, O. F. Olesen, S. Lovestone

Journal:

Journal of Neural Transmission

Year:

2000

Language:

english

File:

PDF, 255 KB

english, 2000

57

Hippocampal Proton MR Spectroscopy in Early Alzheimer’s Disease and Mild Cognitive Impairment

Catherine M. L. Foy, Eileen M. Daly, Amanda Glover, Ruth O’Gorman, Andrew Simmons, Declan G. M. Murphy, Simon Lovestone

Journal:

Brain Topography

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

58

Complement Factor H Y402H Polymorphism is not Associated with Late-onset Alzheimer’s Disease

Gillian Hamilton, Petra Proitsi, Julie Williams, Michael O’Donovan, Michael Owen, John Powell, Simon Lovestone

Journal:

NeuroMolecular Medicine

Year:

2007

Language:

english

File:

PDF, 131 KB

english, 2007

59

Biomarkers for Alzheimer’s disease trials — biomarkers for what? A discussion paper

S. Lovestone, M. Thambisetty

Journal:

The Journal of Nutrition, Health & Aging

Year:

2009

Language:

english

File:

PDF, 137 KB

english, 2009

60

GSK3α exhibits β-catenin and tau directed kinase activities that are modulated by Wnt

Ayodeji A. Asuni, Claudie Hooper, C. Hugh Reynolds, Simon Lovestone, Brian H. Anderton, Richard Killick

Journal:

European Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 646 KB

english, 2006

61

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

Raya Al-Shawi, Angela Hafner, Jessica Olson, Soyon Chun, Saba Raza, Christopher Thrasivoulou, Simon Lovestone, Richard Killick, Paul Simons, Timothy Cowen

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 942 KB

english, 2008

62

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

Raya Al-Shawi, Angela Hafner, Jessica Olsen, Soyon Chun, Saba Raza, Christopher Thrasivoulou, Simon Lovestone, Richard Killick, Paul Simons, Timothy Cowen

Journal:

European Journal of Neuroscience

Year:

2008

File:

PDF, 35 KB

2008

63

TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones

Claudie Hooper, Mahvash Tavassoli, J. Paul Chapple, Dafe Uwanogho, Richard Goodyear, Gerry Melino, Simon Lovestone, Richard Killick

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 614 KB

english, 2006

64

Transcriptomic profiles of Wnt3a and insulin in primary cultured rat cortical neurones

Claudie Hooper, Richard Killick, Cathy Fernandes, David Sugden, Simon Lovestone

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 568 KB

english, 2011

65

MRI Measures of Alzheimer's Disease and the AddNeuroMed Study

Andrew Simmons, Eric Westman, Sebastian Muehlboeck, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Lars-Olof Wahlund, Hilkka Soininen, Simon Lovestone, Alan Evans, Christian Spenger,

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 505 KB

english, 2009

66

Preface

Simon Lovestone

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 31 KB

english, 2009

67

Searching for biomarkers in neurodegeneration

Lovestone, Simon

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 91 KB

english, 2010

68

Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters

Carmine M Pariante, Andrew Makoff, Simon Lovestone, Susan Feroli, Alexandra Heyden, Andrew H Miller, Robert W Kerwin

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 214 KB

english, 2001

69

Association study of the 5-HT2A receptor gene polymorphism, T102C and essential hypertension

Liolitsa, D, Powell, J F, Prince, M, Lovestone, S

Journal:

Journal of Human Hypertension

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

70

Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 β gene and promoter in late onset Alzheimer’s disease

Russ, C, Lovestone, S, Powell, J F

Journal:

Molecular Psychiatry

Year:

2001

Language:

english

File:

PDF, 115 KB

english, 2001

71

The BDNF val66met polymorphism is not associated with late onset Alzheimer's disease in three case–control samples

Li, Y, Rowland, C, Tacey, K, Catanese, J, Sninsky, J, Hardy, J, Powell, J, Lovestone, S, Morris, J C, Thal, L

Journal:

Molecular Psychiatry

Year:

2005

Language:

english

File:

PDF, 60 KB

english, 2005

72

Four Components Describe Behavioral Symptoms in 1,120 Individuals with Late-Onset Alzheimer's Disease

Paul Hollingworth, Marian L. Hamshere, Valentina Moskvina, Kimberley Dowzell, Pamela J. Moore, Catherine Foy, Nicola Archer, Aoibhinn Lynch, Simon Lovestone, Carol Brayne, David C. Rubinsztein, Brian

Journal:

Journal of the American Geriatrics Society

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

73

Identification of cis-regulatory variation influencing protein abundance levels in human plasma

Lourdusamy, A., Newhouse, S., Lunnon, K., Proitsi, P., Powell, J., Hodges, A., Nelson, S. K., Stewart, A., Williams, S., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Lovestone,

Journal:

Human Molecular Genetics

Year:

2012

Language:

english

File:

PDF, 166 KB

english, 2012

74

SORL1 variants and risk of late-onset Alzheimer’s disease

Yonghong Li, Charles Rowland, Joseph Catanese, John Morris, Simon Lovestone, Michael C. O’Donovan, Alison Goate, Michael Owen, Julie Williams, Andrew Grupe

Journal:

Neurobiology of Disease

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

75

Do antidepressants regulate how cortisol affects the brain?

Carmine M. Pariante, Sarah A. Thomas, Simon Lovestone, Andrew Makoff, Robert W. Kerwin

Journal:

Psychoneuroendocrinology

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

76

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

Simon Lovestone, C.Hugh Reynolds, Donna Latimer, Daniel R. Davis, Brian H. Anderton, Jean-Marc Gallo, Diane Hanger, Sandrine Mulot, Betina Marquardt, Silvia Stabel, James R. Woodgett, Christopher C.J.

Journal:

Current Biology

Year:

1994

Language:

english

File:

PDF, 1.17 MB

english, 1994

77

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer’s disease?

Brian H Anderton, Rejith Dayanandan, Richard Killick, Simon Lovestone

Journal:

Molecular Medicine Today

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

78

Schizophrenia as a GSK-3 dysregulation disorder

Simon Lovestone, Richard Killick, Marta Di Forti, Robin Murray

Journal:

Trends in Neurosciences

Year:

2007

Language:

english

File:

PDF, 693 KB

english, 2007

79

Stimulation of MAP kinase by v-raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau

Donna A. Latimer, Jean-Marc Gallo, Simon Lovestone, Christopher C.J. Miller, C. Hugh Reynolds, Betina Marquardt, Silvia Stabel, James R. Woodgett, Brian H. Anderton

Journal:

Year:

1995

Language:

english

File:

PDF, 642 KB

english, 1995

80

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

S. Lovestone, C.L. Hartley, J. Pearce, B.H. Anderton

Journal:

Year:

1996

Language:

english

File:

PDF, 3.15 MB

english, 1996

81

PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3

Fiona Kerr, Annika Rickle, Naushaba Nayeem, Sebastian Brandner, Richard F. Cowburn, Simon Lovestone

Journal:

Year:

2006

Language:

english

File:

PDF, 416 KB

english, 2006

82

Complement activation as a biomarker for Alzheimer's disease

Mohammed Aiyaz, Michelle K. Lupton, Petroula Proitsi, John F. Powell, Simon Lovestone

Journal:

Year:

2012

Language:

english

File:

PDF, 624 KB

english, 2012

83

Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella

Naushaba Nayeem, Fiona Kerr, Heike Naumann, Jackie Linehan, Simon Lovestone, Sebastian Brandner

Journal:

Molecular and Cellular Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

84

Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions

Francis C. Chee, Amritpal Mudher, Matthew F. Cuttle, Tracey A. Newman, Daniel MacKay, Simon Lovestone, David Shepherd

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 718 KB

english, 2005

85

Mutant presenilin 1 proteins induce cell death and reduce tau-dependent processes outgrowth

K. Leroy, A. Boutajangout, J. Richardson, J.N. Octave, S. Lovestone, B.H. Anderton, J.P. Brion

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

86

Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing

Ian J. Deary, Gillian Hamilton, Caroline Hayward, Lawrence J. Whalley, John Powell, John M. Starr, Simon Lovestone

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 72 KB

english, 2005

87

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

Abdul Hye, Fiona Kerr, Nicola Archer, Catherine Foy, Michaela Poppe, Richard Brown, Gillian Hamilton, John Powell, Brian Anderton, Simon Lovestone

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 113 KB

english, 2004

88

TAp73α induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism

Claudie Hooper, Richard Killick, Mahvash Tavassoli, Gerry Melino, Simon Lovestone

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 1007 KB

english, 2006

89

The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons

Claudie Hooper, J. Paul Chapple, Simon Lovestone, Richard Killick

Journal:

Neuroscience Letters

Year:

2007

Language:

english

File:

PDF, 1.27 MB

english, 2007

90

p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

Claudie Hooper, Eirini Meimaridou, Mahvash Tavassoli, Gerry Melino, Simon Lovestone, Richard Killick

Journal:

Neuroscience Letters

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

91

Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease

R. Sims, P. Hollingworth, V. Moskvina, K. Dowzell, M.C. O’Donovan, J. Powell, S. Lovestone, C. Brayne, D. Rubinsztein, M.J. Owen, J. Williams, R. Abraham

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 495 KB

english, 2009

92

β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration

Mirsada Čaušević, Umbreen Farooq, Simon Lovestone, Richard Killick

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 498 KB

english, 2010

93

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

F. Kerr, H. Augustin, M.D.W. Piper, C. Gandy, M.J. Allen, S. Lovestone, L. Partridge

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 2.48 MB

english, 2011

94

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS)

Hui Shi, Olivia Belbin, Christopher Medway, Kristelle Brown, Noor Kalsheker, Minerva Carrasquillo, Petroula Proitsi, John Powell, Simon Lovestone, Alison Goate, Steven Younkin, Peter Passmore, Kevin M

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 2.02 MB

english, 2012

95

Biomarkers for Alzheimer's disease therapeutic trials

Harald Hampel, Gordon Wilcock, Sandrine Andrieu, Paul Aisen, Kaj Blennow, K. Broich, Maria Carrillo, Nick C. Fox, Giovanni B. Frisoni, Maria Isaac, Simon Lovestone, Agneta Nordberg, David Prvulovic, C

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

96

Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3β identified by nano-electrospray mass spectrometry

Graham M Gibb, Janice Pearce, Joanna C Betts, Simon Lovestone, Michael M Hoffmann, Winfried Maerz, Walter P Blackstock, Brian H Anderton

Journal:

Year:

2000

Language:

english

File:

PDF, 450 KB

english, 2000

97

Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3β identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes

James W Connell, Graham M Gibb, Joanna C Betts, Walter P Blackstock, Jean-Marc Gallo, Simon Lovestone, Michael Hutton, Brian H Anderton

Journal:

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

98

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

R. Dayanandan, M. Van Slegtenhorst, T.G.A. Mack, L. Ko, S.-H. Yen, K. Leroy, J.-P. Brion, B.H. Anderton, M. Hutton, S. Lovestone

Journal:

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

99

The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase-3β activity

K. Leroy, R. Menu, J.L. Conreur, R. Dayanandan, S. Lovestone, B.H. Anderton, J.P. Brion

Journal:

Year:

2000

Language:

english

File:

PDF, 342 KB

english, 2000

100

K variant of butyrycholinesterase and late-onset Alzheimer's disease

C Russ, J Powell, S Lovestone, C Holmes

Journal:

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998