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51

Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor

Pia März, Suat Özbek, Martina Fischer, Nicole Voltz, Uwe Otten, Stefan Rose-John

Journal:

Year:

2002

Language:

english

File:

PDF, 261 KB

english, 2002

52

Shedding of interleukin-6 receptor and tumor necrosis factor α : Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins

Katja Althoff, Pranitha Reddy, Nicole Voltz, Stefan Rose-John, Jürgen Müllberg

Journal:

Year:

2000

Language:

english

File:

PDF, 519 KB

english, 2000

53

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

Thomas Jostock, Jürgen Müllberg, Suat Özbek, Raja Atreya, Guido Blinn, Nicole Voltz, Martina Fischer, Markus F. Neurath, Stefan Rose-John

Journal:

Year:

2001

Language:

english

File:

PDF, 660 KB

english, 2001

54

Updating interleukin-6 classic- and trans-signaling

Jürgen Scheller, Joachim Grötzinger, Stefan Rose-John

Journal:

Signal Transduction

Year:

2006

Language:

english

File:

PDF, 2.73 MB

english, 2006

55

Das Zytokinnetzwerk

H. Schooltink, St. Rose-John

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2003

Language:

german

File:

PDF, 432 KB

german, 2003

56

Zytokine in der Medizin

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2003

Language:

german

File:

PDF, 275 KB

german, 2003

57

Zytokine kommen in die Jahre

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2003

Language:

german

File:

PDF, 156 KB

german, 2003

58

Interleukin-6 and its receptor: from bench to bedside

Jürgen Scheller, Stefan Rose-John

Journal:

Medical Microbiology and Immunology

Year:

2006

Language:

english

File:

PDF, 285 KB

english, 2006

59

ADAM17: molekularer Schalter zwischen Entzündung und Regeneration

Athena Chalaris, Stefan Rose-John

Journal:

Year:

2011

Language:

german

File:

PDF, 415 KB

german, 2011

60

The Interleukin-6 Cytokine System Regulates Epidermal Permeability Barrier Homeostasis

Wang, Xu-Ping, Schunck, Michael, Kallen, Karl-Josef, Neumann, Claudia, Trautwein, Christian, Rose-John, Stefan, Proksch, Ehrhardt

Journal:

The Journal of Investigative Dermatology

Year:

2004

Language:

english

File:

PDF, 847 KB

english, 2004

61

Increased inflammation and lethality of Dusp1−/− mice in polymicrobial peritonitis models

Michael Hammer, Bernd Echtenachter, Heike Weighardt, Katrin Jozefowski, Stefan Rose-John, Daniela N. Männel, Bernhard Holzmann, Roland Lang

Journal:

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

62

Interleukin-6 Trans-Signalling in Chronic Inflammation and Cancer

J. Scheller, N. Ohnesorge, S. Rose-John

Journal:

Scandinavian Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 497 KB

english, 2006

63

Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation

Pia März, Thomas Herget, Elke Lang, Uwe Otter, Stefan Rose-John

Journal:

European Journal of Neuroscience

Year:

1997

Language:

english

File:

PDF, 3.29 MB

english, 1997

64

ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock

Udo Conrad, Ingo Plagmann, Sven Malchow, Markus Sack, Doreen M. Floss, Andrei A. Kruglov, Sergei A. Nedospasov, Stefan Rose-John, Jürgen Scheller

Journal:

Plant Biotechnology Journal

Year:

2011

Language:

english

File:

PDF, 275 KB

english, 2011

65

Synthetic Mimetics of the gp130 Binding Site for Viral Interleukin-6 as Inhibitors of the vIL-6–gp130 Interaction

Enge Sudarman, Mariela Bollati-Fogolín, Martin Hafner, Werner Müller, Jürgen Scheller, Stefan Rose-John, Jutta Eichler

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

66

Introduction to Stem Cell Biology in Vitro: Threshold to the Future

C. EAVES, C. MILLER, E. CONNEALLY, J. AUDET, R. OOSTENDORP, J. CASHMANP, P. ZANDSTRA, S. ROSE-JOHN, J. PIRET, A. EAVES

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.53 MB

english, 1999

67

Cytokines and Neurotrophins Interact in Normal and Diseased States

U. OTTEN, P. MÄRZ, K. HEESE, C. HOCK, D. KUNZ, S. ROSE-JOHN

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 527 KB

english, 2000

68

TNF-α-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species

Vahdat, A M, Reiners, K S, Simhadri, V L, Eichenauer, D A, Böll, B, Chalaris, A, Simhadri, V R, Wiegmann, K, Krell, H-W, Rose-John, S

Journal:

Year:

2009

Language:

english

File:

PDF, 604 KB

english, 2009

69

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

Fischer, Martina, Goldschmitt, Jutta, Peschel, Christian, Brakenhoff, Just P. G., Kallen, Karl-Josef, Wollmer, Axel, Grötzinger, Joachim, Rose-John, Stefan

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 505 KB

1997

70

Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism

Chen, Qing, Fisher, Daniel T, Clancy, Kristen A, Gauguet, Jean-Marc M, Wang, Wan-Chao, Unger, Emily, Rose-John, Stefan, von Andrian, Ulrich H, Baumann, Heinz, Evans, Sharon S

Journal:

Nature Immunology

Year:

2006

Language:

english

File:

PDF, 735 KB

english, 2006

71

Transcriptional profiling identifies Id2 function in dendritic cell development

Hacker, Christine, Kirsch, Ralf D., Ju, Xin-Sheng, Hieronymus, Thomas, Gust, Tatjana C., Kuhl, Christiane, Jorgas, Thorsten, Kurz, Steffen M., Rose-John, Stefan, Yokota, Yoshifumi

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 524 KB

english, 2003

72

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK

Watt, Matthew J, Dzamko, Nicolas, Thomas, Walter G, Rose-John, Stefan, Ernst, Matthias, Carling, David, Kemp, Bruce E, Febbraio, Mark A, Steinberg, Gregory R

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

73

More about genetically modified tumour vaccines

Mackiewicz, A, Rose-John, S

Journal:

Year:

1998

Language:

english

File:

PDF, 28 KB

english, 1998

74

Gp130-Signaling synergizes with FL and TPO for the long-term expansion of cord blood progenitors

Rappold, I, Watt, SM, Kusadasi, N, Rose-John, S, Hatzfeld, J, Ploemacher, RE

Journal:

Year:

1999

Language:

english

File:

PDF, 289 KB

english, 1999

75

Murine stromal cells producing hyper-interleukin-6 and Flt3 ligand support expansion of early human hematopoietic progenitor cells without need of exogenous growth factors

Keller, U, Götze, K S, Duyster, J, Schmidt, B, Rose-John, S, Peschel, C

Journal:

Year:

2002

Language:

english

File:

PDF, 228 KB

english, 2002

76

The designer cytokine hyper-IL-6 mediates growth inhibition and GM–CSF-dependent rejection of B16 melanoma cells

&#214, zbek, Suat, Peters, Malte, Breuhahn, Kai, Mann, Amrit, Blessing, Manfred, Fischer, Martina, Schirmacher, Peter, Mackiewicz, Andrzej, Rose-John, Stefan

Journal:

Year:

2001

Language:

english

File:

PDF, 230 KB

english, 2001

77

Virokines in the Pathogenesis of Cancer: Focus on Human Herpesvirus 8

MARIAM KLOUCHE, GIUSEPPE CARRUBA, LUIGI CASTAGNETTA, STEFAN ROSE-JOHN

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 9.13 MB

english, 2004

78

Letter to the Editor:1H,15N and13C Backbone Assignment of the Carboxyl Terminal Domain of the Cytokine Binding Module of the Interleukin-6 Receptor

Andreas Schwantner, Andrew J. Dingley, Suat Özbek, Oliver Hecht, Stefan Rose-John, Joachim Grötzinger

Journal:

Journal of Biomolecular NMR

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

79

Expression of a fusion protein of human ciliary neurotrophic factor and soluble CNTF-Receptor and identification of its activity

Yi Sun, März Pia, Otten Uwe, Ji-guang Ge, Rose-John Stefan

Journal:

Journal of Zhejiang University SCIENCE A

Year:

2003

Language:

english

File:

PDF, 631 KB

english, 2003

80

Ligand/Receptor Signaling Threshold (LIST) Model Accounts for gp130-Mediated Embryonic Stem Cell Self-Renewal Responses to LIF and HIL-6

Sowmya Viswanathan, Tania Benatar, Stefan Rose-John, Doug A. Lauffenburger, Peter W. Zandstra

Journal:

Year:

2002

Language:

english

File:

PDF, 826 KB

english, 2002

81

Multilevel Regulation of IL-6R by IL-6–sIL-6R Fusion Protein According to the Primitiveness of Peripheral Blood-Derived CD133+ Cells

David Campard, Marc Vasse, Stefan Rose-John, Florent Poyer, Marek Lamacz, Jean-Pierre Vannier

Journal:

Year:

2006

Language:

english

File:

PDF, 1.19 MB

english, 2006

82

Maintenance of Pluripotency in Human Embryonic Stem Cells Is STAT3 Independent

Rohan K. Humphrey, Gillian M. Beattie, Ana D. Lopez, Nathan Bucay, Charles C. King, Meri T. Firpo, Stefan Rose-John, Alberto Hayek

Journal:

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

83

Human Interleukin-6 Facilitates Hepatitis B Virus Infection in Vitro and in Vivo

Eithan Galun, Orit Nahor, Ahmed Eid, Oded Jurim, Stefan Rose-John, Hubert E. Blum, Ofer Nussbaum, Ehud Ilan, Nili Daudi, Daniel Shouval, Yair Reisner, Shlomo Dagan

Journal:

Year:

2000

Language:

english

File:

PDF, 969 KB

english, 2000

84

Studies on the structure and function of IL-6 and its receptor

S. Rose-John, G. Dufhues, L. Graeve, A. Krüttgen, C. Lütticken, J. Müllberg, D. Pietzko, H. Schooltink, T. Stoyan, M. Dam, D. Zohlnhöfer, P. C. Heinrich

Journal:

Analytical and Bioanalytical Chemistry

Year:

1992

Language:

english

File:

PDF, 114 KB

english, 1992

85

Alternative assay procedures for cytokines and soluble receptors of the IL-6 family

Birgit Oppmann, Tanja Stoyan, Martina Fischer, Nicole Voltz, Pia März, Stefan Rose-John

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 676 KB

english, 1996

86

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by γ-secretase

Athena Chalaris, Jessica Gewiese, Krzysztof Paliga, Lina Fleig, Alex Schneede, Karsten Krieger, Stefan Rose-John, Jürgen Scheller

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

87

The pro- and anti-inflammatory properties of the cytokine interleukin-6

Jürgen Scheller, Athena Chalaris, Dirk Schmidt-Arras, Stefan Rose-John

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

88

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei Grivennikov, Eliad Karin, Janos Terzic, Daniel Mucida, Guann-Yi Yu, Sivakumar Vallabhapurapu, Jürgen Scheller, Stefan Rose-John, Hilde Cheroutre, Lars Eckmann, Michael Karin

Journal:

Year:

2009

Language:

english

File:

PDF, 1.25 MB

english, 2009

89

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei Grivennikov, Eliad Karin, Janos Terzic, Daniel Mucida, Guann-Yi Yu, Sivakumar Vallabhapurapu, Jürgen Scheller, Stefan Rose-John, Hilde Cheroutre, Lars Eckmann, Michael Karin

Journal:

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

90

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

Marina Lesina, Magdalena U. Kurkowski, Katharina Ludes, Stefan Rose-John, Matthias Treiber, Günter Klöppel, Akihiko Yoshimura, Wolfgang Reindl, Bence Sipos, Shizuo Akira, Roland M. Schmid, Hana Algül

Journal:

Year:

2011

Language:

english

File:

PDF, 2.46 MB

english, 2011

91

The Transcription Factor NFATc2 Controls Apoptosis and Activation of T Cells by IL-6 in Colitis

Benno Weigmann, Hans-Anton Lehr, Stefan Rose-John, Markus Neurath

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

92

Viral Interleukin-6: Structure, pathophysiology and strategies of neutralization

Jan Suthaus, Nina Adam, Joachim Grötzinger, Jürgen Scheller, Stefan Rose-John

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

93

The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer

Athena Chalaris, Christoph Garbers, Björn Rabe, Stefan Rose-John, Jürgen Scheller

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 933 KB

english, 2011

94

The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution

Inken Lorenzen, Weifeng Shang, Markus Perbandt, Maxim V. Petoukhov, Dmitri I. Svergun, Georg H. Waetzig, Stefan Rose-John, Rolf Hilgenfeld, Joachim Grötzinger

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

95

Dendritic cell lineage commitment is instructed by distinct cytokine signals

Kristin M. Seré, Qiong Lin, Piritta Felker, Nina Rehage, Theresa Klisch, Inga Ortseifer, Thomas Hieronymus, Stefan Rose-John, Martin Zenke

Journal:

European Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

96

IL-6-trans-signalling increases rapid-eye-movement sleep in rats

Ulrike May, Thomas Schiffelholz, Paul Christian Baier, James M. Krueger, Stefan Rose-John, Jürgen Scheller

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 275 KB

english, 2009

97

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II

Inken Lorenzen, Juliane Lokau, Stefan Düsterhöft, Ahmad Trad, Christoph Garbers, Jürgen Scheller, Stefan Rose-John, Joachim Grötzinger

Journal:

Year:

2012

Language:

english

File:

PDF, 943 KB

english, 2012

98

Development of a monoclonal antibody-based enzyme-linked immunoabsorbent assay for the binding of gp130 to the IL-6/IL-6R complex and its competitive inhibition

Jürgen Scheller, Marina Kovaleva, Björn Rabe, Jutta Eichler, Karl-Josef Kallen, Stefan Rose-John

Journal:

Journal of Immunological Methods

Year:

2004

Language:

english

File:

PDF, 327 KB

english, 2004

99

IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts

Mariapaola Marino, Flavia Scuderi, Carlo Provenzano, Jürgen Scheller, Stefan Rose-John, Emanuela Bartoccioni

Journal:

Journal of Neuroimmunology

Year:

2008

Language:

english

File:

PDF, 657 KB

english, 2008

100

IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier

Ralf A. Linker, Fred Lühder, Karl-Josef Kallen, De-Hyung Lee, Britta Engelhardt, Stefan Rose-John, Ralf Gold

Journal:

Journal of Neuroimmunology

Year:

2008

Language:

english

File:

PDF, 2.07 MB

english, 2008