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51

Pharmacophore Refinement Guides the Design of Nanomolar-Range Botulinum Neurotoxin Serotype A Light Chain Inhibitors

Nuss, Jonathan E., Dong, Yuxiang, Wanner, Laura M., Ruthel, Gordon, Wipf, Peter, Gussio, Rick, Vennerstrom, Jonathan L., Bavari, Sina, Burnett, James C.

Journal:

ACS Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 2.13 MB

english, 2010

52

Docking Studies on Isoform-Specific Inhibition of Phosphoinositide-3-Kinases

Sabbah, Dima A., Vennerstrom, Jonathan L., Zhong, Haizhen

Journal:

Journal of Chemical Information and Modeling

Year:

2010

Language:

english

File:

PDF, 3.91 MB

english, 2010

53

On the mechanism of action of anesthetics. Direct inhibition of mitochondrial F1-ATPase by N-butanol and tetracaine

Garret Vanderkooi, John Shaw, Connie Storms, Robert Vennerstrom, Derek Chignell

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1981

Language:

english

File:

PDF, 219 KB

english, 1981

54

Electrolysis-mediated irreversible inactivation of lipoxygenase directed toward electroaffinity labelling

Thomas J. Holmes Jr., Jonathan L. Vennerstrom, Varghese John

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 390 KB

english, 1984

55

Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni

Carla Kirchhofer, Mireille Vargas, Olivier Braissant, Yuxiang Dong, Xiaofang Wang, Jonathan L. Vennerstrom, Jennifer Keiser

Journal:

Year:

2011

Language:

english

File:

PDF, 730 KB

english, 2011

56

Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity

James C Burnett, James J Schmidt, Robert G Stafford, Rekha G Panchal, Tam L Nguyen, Ann R Hermone, Jonathan L Vennerstrom, Connor F McGrath, Douglas J Lane, Edward A Sausville, Daniel W Zaharevitz, Ri

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 383 KB

english, 2003

57

Characterization of chloroquine-hematin μ-oxo dimer binding by isothermal titration calorimetry

Sudha Rani Vippagunta, Arnulf Dorn, Robert G. Ridley, Jonathan L. Vennerstrom

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2000

Language:

english

File:

PDF, 247 KB

english, 2000

58

Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant

Sam D Sanderson, Srinivasa R Cheruku, Maniyan P Padmanilayam, Jonathan L Vennerstrom, Geoffrey M Thiele, Matthew I Palmatier, Rick A Bevins

Journal:

International Immunopharmacology

Year:

2003

Language:

english

File:

PDF, 201 KB

english, 2003

59

Prostaglandin-H synthase inhibition by malonamides. Ring-opened analogs of phenylbutazone

Vennerstrom, Jonathan L., Holmes, Thomas J.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 541 KB

english, 1987

60

Binding Selectivity Studies of Phosphoinositide 3-Kinases Using Free Energy Calculations

Sabbah, Dima A., Vennerstrom, Jonathan L., Zhong, Haizhen A.

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

61

Magnetic activity at Mars – Mars Surface Magnetic Observatory

S. Vennerstrom, M. Menvielle, J.M.G. Merayo, T.V. Falkenberg

Journal:

Planetary and Space Science

Year:

2012

Language:

english

File:

PDF, 2.22 MB

english, 2012

62

Long-term and solar cycle variation of the ring current

Vennerstrøm, S., Friis-Christensen, E.

Journal:

Journal of Geophysical Research

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

63

Inhibition of platelet aggregation by novel triphenylethylene analogs

Gundu H.R. Rao, Vargese John, Timothy D. Hill, J.L. Vennerstrom, James G. White, T.J. Holmes Jr.

Journal:

Thrombosis Research

Year:

1986

Language:

english

File:

PDF, 826 KB

english, 1986

64

Stimulation of the cyclooxygenase activity of prostaglandin H synthase by salicylate-derived quinhydrones

T.J. Holmes Jr., V. John, J. Vennerstrom, Richard J. Kulmacz, William E.M. Lands

Journal:

Year:

1984

Language:

english

File:

PDF, 326 KB

english, 1984

65

N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα)

Dima A. Sabbah, Neka A. Simms, Wang Wang, Yuxiang Dong, Edward L. Ezell, Michael G. Brattain, Jonathan L. Vennerstrom, Haizhen A. Zhong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

66

A Comparison and Analysis of Several Ways to Promote Haematin (Haem) Polymerisation and an Assessment of Its Initiation In Vitro

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile, André Bubendorf, Jonathan L. Vennerstrom, Robert G. Ridley

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 610 KB

english, 1998

67

Polar cap index as a proxy for hemispheric Joule heating

Chun, Francis K., Knipp, Delores J., McHarg, Matthew G., Lu, Gang, Emery, Barbara A., Vennerstrøm, Susanne, Troshichev, Oleg A.

Journal:

Geophysical Research Letters

Year:

1999

Language:

english

File:

PDF, 497 KB

english, 1999

68

Dayside magnetic ULF power at high latitudes: A possible long-term proxy for the solar wind velocity?

Vennerstrøm, Susanne

Journal:

Journal of Geophysical Research

Year:

1999

Language:

english

File:

PDF, 1.64 MB

english, 1999

69

Field-aligned currents in the dayside cusp and polar cap region during northward IMF

Vennerstrøm, S.

Journal:

Journal of Geophysical Research

Year:

2002

Language:

english

File:

PDF, 214 KB

english, 2002

70

Highlights From AGU's virtual session on new magnetic field satellites

Purucker, Michael, McCreadie, Heather, Vennerstrøm, Suzanne, Hulot, Gauthier, Olsen, Nils, Lühr, Hermann, Garnero, Edward

Journal:

Eos Transactions American Geophysical Union

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

71

The magnetic field in the pile-up region at Mars, and its variation with the solar wind

Vennerstrom, S.

Journal:

Geophysical Research Letters

Year:

2003

Language:

english

File:

PDF, 189 KB

english, 2003

72

Field-aligned currents during northward interplanetary magnetic field: Morphology and causes

Vennerstrom, S.

Journal:

Journal of Geophysical Research

Year:

2005

Language:

english

File:

PDF, 4.30 MB

english, 2005

73

Climatologies of nighttime upper thermospheric winds measured by ground-based Fabry-Perot interferometers during geomagnetically quiet conditions: 2. High-latitude circulation and interplanetary magnetic field dependence

Emmert, J. T., Hernandez, G., Jarvis, M. J., Niciejewski, R. J., Sipler, D. P., Vennerstrom, S.

Journal:

Journal of Geophysical Research

Year:

2006

Language:

english

File:

PDF, 487 KB

english, 2006

74

On the cause of IMF B y related mid- and low latitude magnetic disturbances

Vennerstrom, S., Christiansen, F., Olsen, N., Moretto, T.

Journal:

Geophysical Research Letters

Year:

2007

Language:

english

File:

PDF, 481 KB

english, 2007

75

Multipoint observations of coronal mass ejection and solar energetic particle events on Mars and Earth during November 2001

Falkenberg, T. V., Vennerstrom, S., Brain, D. A., Delory, G., Taktakishvili, A.

Journal:

Journal of Geophysical Research

Year:

2011

Language:

english

File:

PDF, 3.19 MB

english, 2011

76

Evaluating predictions of ICME arrival at Earth and Mars

Falkenberg, T. V., Taktakishvili, A., Pulkkinen, A., Vennerstrom, S., Odstrcil, D., Brain, D., Delory, G., Mitchell, D.

Journal:

Space Weather The International Journal of Research and Applications

Year:

2011

Language:

english

File:

PDF, 2.61 MB

english, 2011

77

Comparison between the polar cap index, PC , and the auroral electrojet indices AE , AL , and AU

Vennerstrøm, S., Friis-Christensen, E., Troshichev, O. A., Andersen, V. G.

Journal:

Journal of Geophysical Research

Year:

1991

Language:

english

File:

PDF, 1.44 MB

english, 1991

78

Features of steady magnetospheric convection

Yahnin, A., Malkov, M. V., Sergeev, V. A., Pellinen, R. J., Aulamo, O., Vennerström, S., Friis-Christensen, E., Lassen, K., Danielsen, C., Craven, J. D., Deehr, C., Frank, L. A.

Journal:

Journal of Geophysical Research

Year:

1994

Language:

english

File:

PDF, 1.59 MB

english, 1994

79

Progressing polar convection disturbances: Signature of an open magnetosphere

Stauning, P., Friis-Christensen, E., Rasmussen, O., Vennerstrøm, S.

Journal:

Journal of Geophysical Research

Year:

1994

Language:

english

File:

PDF, 1.71 MB

english, 1994

80

Ionospheric currents and F-region plasma boundaries near the dayside cusp

Vennerstrom, S., Friis-Christensen, E., Jorgensen, T. S., Rasmussen, O., Clauer, C. R., Wickwar, V. B.

Journal:

Geophysical Research Letters

Year:

1984

Language:

english

File:

PDF, 489 KB

english, 1984

81

Observation of interplanetary magnetic field and of ionospheric plasma convection in the vicinity of the dayside polar cleft

Clauer, C. R., Banks, P. M., Smith, A. Q., Jorgensen, T. S., Friis-Christensen, E., Vennerstrom, S., Wickwar, V. B., Kelly, J. D., Doupnik, J.

Journal:

Geophysical Research Letters

Year:

1984

Language:

english

File:

PDF, 409 KB

english, 1984

82

Ionospheric traveling convection vortices observed near the polar cleft: A triggered response to sudden changes in the solar wind

Friis-Christensen, E., McHenry, M. A., Clauer, C. R., Vennerstrøm, S.

Journal:

Geophysical Research Letters

Year:

1988

Language:

english

File:

PDF, 443 KB

english, 1988

83

On the role of IMF B y in generating the electric field responsible for the flow across the polar cap

Vennerstrøm, Susanne, Friis-Christensen, Eigil

Journal:

Journal of Geophysical Research

Year:

1987

Language:

english

File:

PDF, 773 KB

english, 1987

84

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

Moehrle, Joerg J., Duparc, Stephan, Siethoff, Christoph, van Giersbergen, Paul L. M., Craft, J. Carl, Arbe-Barnes, Sarah, Charman, Susan A., Gutierrez, Maria, Wittlin, Sergio, Vennerstrom, Jonathan L.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

85

Structural Specificity of Chloroquine−Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth

Vippagunta, Sudha Rani, Dorn, Arnulf, Matile, Hugues, Bhattacharjee, Apurba K., Karle, Jean M., Ellis, William Y., Ridley, Robert G., Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 196 KB

english, 1999

86

Carbon Isosteres of the 4-Aminopyridine Substructure of Chloroquine: Effects on p K a , Hematin Binding, Inhibition of Hemozoin Formation, and Parasite Growth

Cheruku, Srinivasa R., Maiti, Souvik, Dorn, Arnulf, Scorneaux, Bernard, Bhattacharjee, Apurba K., Ellis, William Y., Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

87

CLONORCHICIDAL PROPERTIES OF THE SYNTHETIC TRIOXOLANE OZ78

Keiser, Jennifer, Xiao, Shu-Hua, Dong, Yuxiang, Utzinger, Jürg, Vennerstrom, Jonathan L.

Journal:

Journal of Parasitology

Year:

2007

Language:

english

File:

PDF, 1.71 MB

english, 2007

88

Dispiro-1,2,4-trioxane Analogues of a Prototype Dispiro-1,2,4-trioxolane: Mechanistic Comparators for Artemisinin in the Context of Reaction Pathways with Iron(II)

Tang, Yuanqing, Dong, Yuxiang, Wang, Xiaofang, Sriraghavan, Kamaraj, Wood, James K., Vennerstrom, Jonathan L.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

89

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides

Vennerstrom, Jonathan L., Fu, Hong Ning, Ellis, William Y., Ager, Arba L., Wood, James K., Andersen, Steven L., Gerena, Lucia, Milhous, Wilbur K.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 678 KB

english, 1992

90

Spiro- and Dispiro-1,2-dioxolanes: Contribution of Iron(II)-Mediated One-Electron vs Two-Electron Reduction to the Activity of Antimalarial Peroxides

Wang, Xiaofang, Dong, Yuxiang, Wittlin, Sergio, Creek, Darren, Chollet, Jacques, Charman, Susan A., Santo Tomas, Josefina, Scheurer, Christian, Snyder, Christopher, Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 123 KB

english, 2007

91

Polyfluorinated Bis-styrylbenzene β-Amyloid Plaque Binding Ligands

Flaherty, Daniel P., Walsh, Shannon M., Kiyota, Tomomi, Dong, Yuxiang, Ikezu, Tsuneya, Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 584 KB

english, 2007

92

Synthesis and Antimalarial Activity of 11 Dispiro-1,2,4,5-tetraoxane Analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes Substituted at the 1 and 10 Positions with Unsaturated and Polar Functional Groups

Dong, Yuxiang, Matile, Hugues, Chollet, Jacques, Kaminsky, Ronald, Wood, James K., Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 41 KB

english, 1999

93

Methyl-Substituted Dispiro-1,2,4,5-tetraoxanes: Correlations of Structural Studies with Antimalarial Activity

McCullough, Kevin J., Wood, James K., Bhattacharjee, Apurba K., Dong, Yuxiang, Kyle, Dennis E., Milhous, Wilbur K., Vennerstrom, Jonathan L.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 61 KB

english, 2000

94

Preparation and evaluation of electrophilic derivatives of phenylbutazone as inhibitors of prostaglandin-H-synthase

Vennerstrom, Jonathan L., Holmes, Thomas J.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 798 KB

english, 1987

95

Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes

Küster, Tatiana, Kriegel, Nadja, Stadelmann, Britta, Wang, Xiaofang, Dong, Yuxiang, Vennerstrom, Jonathan L., Keiser, Jennifer, Hemphill, Andrew

Journal:

International Journal of Antimicrobial Agents

Year:

2014

Language:

english

File:

PDF, 3.80 MB

english, 2014

96

Synthesis and Antimalarial Activity of Sixteen Dispiro-1,2,4,5-tetraoxanes: Alkyl-Substituted 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes

Vennerstrom, Jonathan L., Dong, Yuxiang, Andersen, Steven L., Ager,, Arba L., Fu, Hong-ning, Miller, Robert E., Wesche, David L., Kyle, Dennis E., Gerena, Lucia, Walters, Sheri M., Wood, James K., Edw

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 67 KB

english, 2000

97

Activity of diimidazoline amides against African trypanosomiasis

Dong, Yuxiang, Wang, Xiaofang, Cal, Monica, Kaiser, Marcel, Vennerstrom, Jonathan L.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 685 KB

english, 2014

98

Protoberberine alkaloids as antimalarials

Vennerstrom, Jonathan L., Klayman, Daniel L.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 557 KB

english, 1988

99

Effect of ozonide OZ418 againstSchistosoma japonicumharbored in mice

Xue, Jian, Wang, Xiaofang, Dong, Yuxiang, Vennerstrom, Jonathan L., Xiao, Shu-hua

Journal:

Parasitology Research

Year:

2014

Language:

english

File:

PDF, 242 KB

english, 2014

100

A 3D QSAR Pharmacophore Model and Quantum Chemical Structure-Activity Analysis of Chloroquine(CQ)-Resistance Reversal

Bhattacharjee, A.K., Kyle, D.E., Vennerstrom, J.L., Milhous, W.K.

Journal:

Journal of Chemical Information and Modeling

Year:

2002

Language:

english

File:

PDF, 497 KB

english, 2002