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1

Uric acid and Hypertension: An Update with Recommendations

Sanchez-Lozada, L G, Rodriguez-Iturbe, B, Kelley, E E, Nakagawa, T, Madero, M, Feig, D I, Borghi, C, Piani, F, Cara-Fuentes, G, Bjornstad, P, Lanaspa, M A, Johnson, R J

Journal:

American Journal of Hypertension

Year:

2020

Language:

english

File:

PDF, 1005 KB

english, 2020

2

Fructose contributes to the Warburg effect for cancer growth

Nakagawa, Takahiko, Lanaspa, Miguel A., Millan, Inigo San, Fini, Mehdi, Rivard, Christopher J., Sanchez-Lozada, Laura G., Andres-Hernando, Ana, Tolan, Dean R., Johnson, Richard J.

Journal:

Cancer & Metabolism

Year:

2020

File:

PDF, 1.63 MB

2020

3

Uric Acid and Fructose: Potential Biological Mechanisms

Lanaspa, Miguel A., Tapia, Edilia, Soto, Virgilia, Sautin, Yuri, Sánchez-Lozada, Laura Gabriela

Journal:

Seminars in Nephrology

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

4

Perspective: A Historical and Scientific Perspective of Sugar and Its Relation with Obesity and Diabetes

Johnson, Richard J, Sánchez-Lozada, Laura G, Andrews, Peter, Lanaspa, Miguel A

Journal:

Advances in Nutrition: An International Review Journal

Year:

2017

Language:

english

File:

PDF, 922 KB

english, 2017

5

Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver

Laura G. Sánchez-Lozada, Wei Mu, Carlos Roncal, Yuri Y. Sautin, Manal Abdelmalek, Sirirat Reungjui, MyPhuong Le, Takahiko Nakagawa, Hui Y. Lan, Xuequing Yu, Richard J. Johnson

Journal:

European Journal of Nutrition

Year:

2010

Language:

english

File:

PDF, 336 KB

english, 2010

6

Dietary Fructose and Hypertension

Magdalena Madero, Santos E. Perez-Pozo, Diana Jalal, Richard J. Johnson, Laura G. Sánchez-Lozada

Journal:

Current Hypertension Reports

Year:

2011

Language:

english

File:

PDF, 194 KB

english, 2011

7

Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response

Perez-Pozo, S E, Schold, J, Nakagawa, T, Sánchez-Lozada, L G, Johnson, R J, Lillo, J López

Journal:

International Journal of Obesity

Year:

2009

Language:

english

File:

PDF, 336 KB

english, 2009

8

Effects of Excessive Fructose Intake on Health

Johnson, Richard J., Lanaspa, Miguel A., Roncal-Jimenez, Carlos, Sanchez-Lozada, Laura G.

Journal:

Annals of Internal Medicine

Year:

2012

Language:

english

File:

PDF, 108 KB

english, 2012

9

The discovery of hypertension: evolving views on the role of the kidneys, and current hot topics

Johnson, Richard J., Lanaspa, Miguel A., Gabriela Sánchez-Lozada, L., Rodriguez-Iturbe, Bernardo

Journal:

AJP: Renal Physiology

Year:

2015

Language:

english

File:

PDF, 685 KB

english, 2015

10

Fructose Induces the Inflammatory Molecule ICAM-1 in Endothelial Cells

Glushakova, O., Kosugi, T., Roncal, C., Mu, W., Heinig, M., Cirillo, P., Sanchez-Lozada, L. G., Johnson, R. J., Nakagawa, T.

Journal:

Journal of the American Society of Nephrology

Year:

2008

Language:

english

File:

PDF, 370 KB

english, 2008

11

Low Fructose and Low Salt Diets Increase Mitochondrial DNA in White Blood Cells of Overweight Subjects

Hernández-Ríos, R., Hernández-Estrada, S., Cruz-Robles, D., Hernández-Lobato, S., Villalobos-Martín, M., Johnson, R., Rodríguez-Castellanos, F., Salazar, J., García-Arroyo, F., Sánchez-Lozada, L., Mad

Journal:

Experimental and Clinical Endocrinology & Diabetes

Year:

2013

Language:

english

File:

PDF, 202 KB

english, 2013

12

Effects of acute and chronic L-arginine treatment in experimental hyperuricemia

Sanchez-Lozada, L. G., Tapia, E., Lopez-Molina, R., Nepomuceno, T., Soto, V., Avila-Casado, C., Nakagawa, T., Johnson, R. J., Herrera-Acosta, J., Franco, M.

Journal:

AJP Renal Physiology

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

13

A Pilot Study On The Impact Of a Low Fructose Diet and Allopurinol on Clinic Blood Pressure amongst Overweight and Prehypertensive Subjects: A randomized placebo controlled trial

Madero, Magdalena, Rodríguez Castellanos, Francisco E., Jalal, Diana, Villalobos-Martín, Maria, Salazar, Jonathan, Vazquez-Rangel, Armando, Johnson, Richard J., Sanchez-Lozada, L. Gabriela

Journal:

Journal of the American Society of Hypertension

Year:

2015

Language:

english

File:

PDF, 555 KB

english, 2015

14

Oxidative stress with an activation of the renin–angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction

Yu, Min-A, Sánchez-Lozada, Laura G, Johnson, Richard J, Kang, Duk-Hee

Journal:

Journal of Hypertension

Year:

2010

Language:

english

File:

PDF, 387 KB

english, 2010

15

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

Sánchez-Lozada, Laura G., Andres-Hernando, Ana, Garcia-Arroyo, Fernando E., Cicerchi, Christina, Li, Nanxing, Kuwabara, Masanari, Roncal-Jimenez, Carlos A., Johnson, Richard J., Lanaspa, Miguel A.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 2.99 MB

english, 2019

16

Fructose Production and Metabolism in the Kidney

Nakagawa, Takahiko, Johnson, Richard J., Andres-Hernando, Ana, Roncal-Jimenez, Carlos, Sanchez-Lozada, Laura G., Tolan, Dean R., Lanaspa, Miguel A.

Journal:

Journal of the American Society of Nephrology

Year:

2020

File:

PDF, 1.05 MB

2020

17

Cerebral Fructose Metabolism as a Potential Mechanism Driving Alzheimerâs Disease

Johnson, Richard J., Gomez-Pinilla, Fernando, Nagel, Maria, Nakagawa, Takahiko, Rodriguez-Iturbe, Bernardo, Sanchez-Lozada, Laura G., Tolan, Dean R., Lanaspa, Miguel A.

Journal:

Frontiers in Aging Neuroscience

Year:

2020

File:

PDF, 1.69 MB

2020

18

Mycophenolate mofetil prevents arteriolopathy and renal injury in subtotal ablation despite persistent hypertension

Tapia, Edilia, Franco, Martha, Sanchez-Lozada, Laura G., Soto, Virgilia, Avila-Casado, Carmen, Santamaria, Jose, Quiroz, Yasmir, Rodriguez-Iturbe, Bernardo, Herrera-Acosta, Jaime

Journal:

Kidney International

Year:

2003

Language:

english

File:

PDF, 1.54 MB

english, 2003

19

Glomerular hemodynamic changes associated with arteriolar lesions and tubulointerstitial inflammation

Sanchez-Lozada, Laura G., Tapia, Edilia, Johnson, Richard J., Rodriguez-Iturbe, Bernardo, Herrera-Acosta, Jaime

Journal:

Kidney International

Year:

2003

Language:

english

File:

PDF, 546 KB

english, 2003

20

Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society?

Richard J. Johnson, Yuri Y. Sautin, William J. Oliver, Carlos Roncal, Wei Mu, L. Gabriela Sanchez-Lozada, Bernardo Rodriguez-Iturbe, Takahiko Nakagawa, Steven A. Benner

Journal:

Journal of Comparative Physiology B

Year:

2009

Language:

english

File:

PDF, 399 KB

english, 2009

21

The conundrum of hyperuricemia, metabolic syndrome, and renal disease

Takahiko Nakagawa, Pietro Cirillo, Waichi Sato, Michael Gersch, Yuri Sautin, Carlos Roncal, Wei Mu, L. Gabriela Sánchez-Lozada, Richard J. Johnson

Journal:

Internal and Emergency Medicine

Year:

2008

Language:

english

File:

PDF, 215 KB

english, 2008

22

Reply from the Authors

Sanchez-Lozada, Laura G., Rodriguez-Iturbe, Bernardo, Johnson, Richard J., Herrera-Acosta, Jaime

Journal:

Kidney International

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

23

Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats

Sanchez-Lozada, Laura G., Tapia, Edilia, Santamaria, Jose, Avila-Casado, Carmen, Soto, Virgilia, Nepomuceno, Tomas, Rodriguez-Iturbe, Bernardo, Johnson, Richard J., Herrera-Acosta, Jaime

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 321 KB

english, 2005

24

Unearthing uric acid: An ancient factor with recently found significance in renal and cardiovascular disease

Nakagawa, T, Kang, D-H, Feig, D, Sanchez-Lozada, L G, Srinivas, T R, Sautin, Y, Ejaz, A A, Segal, M, Johnson, R J

Journal:

Kidney International

Year:

2006

Language:

english

File:

PDF, 84 KB

english, 2006

25

Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake

Carlos A. Roncal-Jimenez, Miguel A. Lanaspa, Christopher J. Rivard, Takahiko Nakagawa, L Gabriela Sanchez-Lozada, Diana Jalal, Ana Andres-Hernando, Katsuyuki Tanabe, Magdalena Madero, Nanxing Li, Chri

Journal:

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

26

Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome

Sanchez-Lozada, L. G., Tapia, E., Bautista-Garcia, P., Soto, V., Avila-Casado, C., Vega-Campos, I. P., Nakagawa, T., Zhao, L., Franco, M., Johnson, R. J.

Journal:

AJP Renal Physiology

Year:

2008

Language:

english

File:

PDF, 807 KB

english, 2008

27

Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats

Sanchez-Lozada, L. G., Tapia, E., Jimenez, A., Bautista, P., Cristobal, M., Nepomuceno, T., Soto, V., Avila-Casado, C., Nakagawa, T., Johnson, R. J., Herrera-Acosta, J., Franco, M.

Journal:

AJP Renal Physiology

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

28

Uric Acid and the Origins of Hypertension

Feig, Daniel I., Madero, Magdalena, Jalal, Diana I., Sanchez-Lozada, L. Gabriela, Johnson, Richard J.

Journal:

The Journal of Pediatrics

Year:

2013

Language:

english

File:

PDF, 248 KB

english, 2013

29

Redefining metabolic syndrome as a fat storage condition based on studies of comparative physiology

Johnson, Richard J., Stenvinkel, Peter, Martin, Sandra L., Jani, Alkesh, Sánchez-Lozada, Laura Gabriela, Hill, James O., Lanaspa, Miguel A.

Journal:

Year:

2013

Language:

english

File:

PDF, 401 KB

english, 2013

30

Sugar, Uric Acid, and the Etiology of Diabetes and Obesity

Johnson, R. J., Nakagawa, T., Sanchez-Lozada, L. G., Shafiu, M., Sundaram, S., Le, M., Ishimoto, T., Sautin, Y. Y., Lanaspa, M. A.

Journal:

Year:

2013

Language:

english

File:

PDF, 445 KB

english, 2013

31

Uric Acid-Induced Endothelial Dysfunction Is Associated with Mitochondrial Alterations and Decreased Intracellular ATP Concentrations

Sánchez-Lozada, Laura Gabriela, Lanaspa, Miguel A., Cristóbal-García, Magdalena, García-Arroyo, Fernando, Soto, Virgilia, Cruz-Robles, David, Nakagawa, Takahiko, Yu, Min A, Kang, Duk-Hee, Johnson, Ric

Journal:

Nephron Experimental Nephrology

Year:

2012

Language:

english

File:

PDF, 339 KB

english, 2012

32

Hemodynamics of hyperuricemia

Sánchez-Lozada, Laura G., Tapia, Edilia, Rodríguez-Iturbe, Bernardo, Johnson, Richard J., Herrera-Acosta, Jaime

Journal:

Seminars in Nephrology

Year:

2005

Language:

english

File:

PDF, 158 KB

english, 2005

33

Uric acid and chronic kidney disease: which is chasing which?

Johnson, R. J., Nakagawa, T., Jalal, D., Sanchez-Lozada, L. G., Kang, D.-H., Ritz, E.

Journal:

Nephrology Dialysis Transplantation

Year:

2013

Language:

english

File:

PDF, 261 KB

english, 2013

34

The Rediscovery of Uric Acid in Cardiorenal Disease: Introduction

Johnson, Richard J., Kanbay, Mehmet, Sánchez-Lozada, Laura Gabriela

Journal:

Seminars in Nephrology

Year:

2011

Language:

english

File:

PDF, 152 KB

english, 2011

35

Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?

Johnson, Richard J., Perez-Pozo, Santos E., Sautin, Yuri Y., Manitius, Jacek, Sanchez-Lozada, Laura Gabriela, Feig, Daniel I., Shafiu, Mohamed, Segal, Mark, Glassock, Richard J., Shimada, Michiko, Ron

Journal:

Endocrine Reviews

Year:

2009

Language:

english

File:

PDF, 442 KB

english, 2009

36

Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia

Sanchez-Lozada, L. G., Tapia, E., Soto, V., Avila-Casado, C., Franco, M., Zhao, L., Johnson, R. J.

Journal:

Nephrology Dialysis Transplantation

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

37

Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice

Kosugi, T., Nakayama, T., Heinig, M., Zhang, L., Yuzawa, Y., Sanchez-Lozada, L. G., Roncal, C., Johnson, R. J., Nakagawa, T.

Journal:

AJP Renal Physiology

Year:

2009

Language:

english

File:

PDF, 1.92 MB

english, 2009

38

Umami: The Taste That Drives Purine Intake

JOHNSON, R. J., NAKAGAWA, T., SANCHEZ-LOZADA, L. G., LANASPA, M. A., TAMURA, Y., TANABE, K., ISHIMOTO, T., THOMAS, J., INABA, S., KITAGAWA, W., RIVARD, C. J.

Journal:

The Journal of Rheumatology

Year:

2013

Language:

english

File:

PDF, 249 KB

english, 2013

39

Chronic kidney disease: Mesoamerican nephropathy—new clues to the cause

Johnson, Richard J., Sánchez-Lozada, Laura G.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2013

Language:

english

File:

PDF, 94 KB

english, 2013

40

Dietary fructose causes tubulointerstitial injury in the normal rat kidney

Nakayama, T., Kosugi, T., Gersch, M., Connor, T., Sanchez-Lozada, L. G., Lanaspa, M. A., Roncal, C., Perez-Pozo, S. E., Johnson, R. J., Nakagawa, T.

Journal:

AJP Renal Physiology

Year:

2010

Language:

english

File:

PDF, 3.72 MB

english, 2010

41

The Effect of Fructose on Renal Biology and Disease

Johnson, R. J., Sanchez-Lozada, L. G., Nakagawa, T.

Journal:

Journal of the American Society of Nephrology

Year:

2010

Language:

english

File:

PDF, 238 KB

english, 2010

42

Curcumin prevents maleate-induced nephrotoxicity: Relation to hemodynamic alterations, oxidative stress, mitochondrial oxygen consumption and activity of respiratory complex I

Tapia, E., Sánchez-Lozada, L. G., García-Niño, W. R., García, E., Cerecedo, A., García-Arroyo, F. E., Osorio, H., Arellano, A., Cristóbal-García, M., Loredo, M. L., Molina-Jijón, E., Hernández-Damián,

Journal:

Free Radical Research

Year:

2014

Language:

english

File:

PDF, 3.13 MB

english, 2014

43

Uric Acid: More to Learn, More Experiments to Do

Johnson, R. J., Rivard, C., Nakagawa, T., Sautin, Y. Y., Sanchez-Lozada, L. G.

Journal:

American Journal of Hypertension

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

44

Hypertension: New treatment target for systolic blood pressure?

Johnson, Richard J., Sánchez-Lozada, Laura G., Rodríguez-Iturbe, Bernardo

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2009

Language:

english

File:

PDF, 126 KB

english, 2009

45

Renal tight junction proteins are decreased in cisplatin-induced nephrotoxicity in rats

Trujillo, Joyce, Molina-Jijón, Eduardo, Medina-Campos, Omar Noel, Rodríguez-Muñoz, Rafael, Reyes, José Luis, Loredo, María L., Tapia, Edilia, Sánchez-Lozada, Laura Gabriela, Barrera-Oviedo, Diana, Ped

Journal:

Toxicology Mechanisms and Methods

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

46

Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress: POTENTIAL ROLE IN FRUCTOSE-DEPENDENT AND -INDEPENDENT FATTY LIVER

Lanaspa, M. A., Sanchez-Lozada, L. G., Choi, Y.-J., Cicerchi, C., Kanbay, M., Roncal-Jimenez, C. A., Ishimoto, T., Li, N., Marek, G., Duranay, M., Schreiner, G., Rodriguez-Iturbe, B., Nakagawa, T., Ka

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

47

Nifedipine Prevents Changes in Nitric Oxide Synthase mRNA Levels Induced by Cyclosporine

Sanchez-Lozada, L. G., Gamba, G., Bolio, A., Jimenez, F., Herrera-Acosta, J., Bobadilla, N. A.

Journal:

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

48

Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia

Sanchez-Lozada, L. G., Soto, V., Tapia, E., Avila-Casado, C., Sautin, Y. Y., Nakagawa, T., Franco, M., Rodriguez-Iturbe, B., Johnson, R. J.

Journal:

AJP Renal Physiology

Year:

2008

Language:

english

File:

PDF, 813 KB

english, 2008

49

Sildenafil Treatment Prevents Glomerular Hypertension and Hyperfiltration in Rats with Renal Ablation

Tapia, Edilia, Sanchez-Lozada, Laura G., Soto, Virgilia, Manrique, Andrés M., Ortiz-Vega, Karla M., Santamaría, José, Medina-Campos, Omar N., Cristóbal, Magdalena, Avila-Casado, Carmen, Pedraza-Chaver

Journal:

Kidney & Blood Pressure Research

Year:

2012

Language:

english

File:

PDF, 674 KB

english, 2012

50

Response to Dr White

Perez-Pozo, S E, Schold, J, Nakagawa, T, Sanchez-Lozada, L G, Johnson, R J, Lopez-Lillo, J

Journal:

International Journal of Obesity

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

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