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101

Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation

Liu, Tong, Wu, Changgong, Jain, Mohit Raja, Nagarajan, Narayani, Yan, Lin, Dai, Huacheng, Cui, Chuanlong, Baykal, Ahmet, Pan, Stacey, Ago, Tetsuro, Sadoshima, Junichi, Li, Hong

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2015

Language:

english

File:

PDF, 669 KB

english, 2015

102

Pivotal role of miR-448 in the development of ROS-induced cardiomyopathy

Kyrychenko, Sergii, Kyrychenko, Viktoriia, Badr, Myriam A., Ikeda, Yoshiyuki, Sadoshima, Junichi, Shirokova, Natalia

Journal:

Cardiovascular Research

Year:

2015

Language:

english

File:

PDF, 1022 KB

english, 2015

103

Detrimental role of pericyte Nox4 in the acute phase of brain ischemia

Nishimura, Ataru, Ago, Tetsuro, Kuroda, Junya, Arimura, Koichi, Tachibana, Masaki, Nakamura, Kuniyuki, Wakisaka, Yoshinobu, Sadoshima, Junichi, Iihara, Koji, Kitazono, Takanari

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

104

Autophagy: a Novel Protective Mechanism in Chronic Ischemia

Yan, Lin, Sadoshima, Junichi, Vatner, Dorothy E., Vatner, Stephen F.

Journal:

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

105

Two Cases of Dilated Cardiomyopathy Complicated by Left Ventricular Aneurysm

Sadoshima, Junichi, Taira, Yuji, Shimokawa, Hiroaki, Koyanagi, Samon, Takeshita, Akira, Nakamura, Motoomi

Journal:

Year:

1987

Language:

english

File:

PDF, 1.42 MB

english, 1987

106

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure-Overload-Induced Mitochondrial Dysfunction and Heart Failure

Shirakabe, Akihiro, Zhai, Peiyong, Ikeda, Yoshiyuki, Saito, Toshiro, Maejima, Yasuhiro, Hsu, Chiao-Po, Nomura, Masatoshi, Egashira, Kensuke, Levine, Beth, Sadoshima, Junichi

Journal:

Year:

2016

Language:

english

File:

PDF, 3.05 MB

english, 2016

107

Evaluating mitochondrial autophagy in the mouse heart

Shirakabe, Akihiro, Fritzky, Luke, Saito, Toshiro, Zhai, Peiyong, Miyamoto, Shigeki, Gustafsson, Åsa B., Kitsis, Richard N., Sadoshima, Junichi

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2016

Language:

english

File:

PDF, 990 KB

english, 2016

108

Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes

Hsu, Chiao-Po, Hariharan, Nirmala, Alcendor, Ralph R., Oka, Shinichi, Sadoshima, Junichi

Journal:

Year:

2009

Language:

english

File:

PDF, 870 KB

english, 2009

109

Mitochondrial autophagy in cardiomyopathy

Tong, Mingming, Sadoshima, Junichi

Journal:

Current Opinion in Genetics & Development

Year:

2016

Language:

english

File:

PDF, 524 KB

english, 2016

110

Thioredoxin-1 attenuates ventricular and mitochondrial post-ischemic dysfunction in the stunned myocardium of transgenic mice

Perez, Virginia, D´Annunzio, Verónica, Valdez, Laura Beatriz, Zaobornyj, Tamara, Bombicino, Silvina, Mazo, Tamara, Longo Carbajosa, Nadia, Gironacci, Mariela, Boveris, Alberto, Sadoshima, Junichi, Gel

Journal:

Antioxidants & Redox Signaling

Year:

2016

Language:

english

File:

PDF, 781 KB

english, 2016

111

Poldip2 negatively regulates matrix synthesis at focal adhesions

Matsushima, Shouji, Zablocki, Daniela, Tsutsui, Hiroyuki, Sadoshima, Junichi

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2016

Language:

english

File:

PDF, 198 KB

english, 2016

112

Sex differences in response to miRNA-34a therapy in mouse models of cardiac disease: Identification of sex-, disease- and treatment-regulated miRNAs

Bernardo, Bianca C., Ooi, Jenny Y.Y., Matsumoto, Aya, Tham, Yow Keat, Singla, Saloni, Kiriazis, Helen, Patterson, Natalie L., Sadoshima, Junichi, Obad, Susanna, Lin, Ruby C. Y., McMullen, Julie R.

Journal:

The Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 897 KB

english, 2016

113

Pharmacological Modulation of Autophagy During Cardiac Stress

Sciarretta, Sebastiano, Zhai, Peiyong, Volpe, Massimo, Sadoshima, Junichi

Journal:

Journal of Cardiovascular Pharmacology

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

114

NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in Heart

Matsuda, Takahisa, Zhai, Peiyong, Sciarretta, Sebastiano, Zhang, Yu, Jeong, Jae Im, Ikeda, Shohei, Park, Ji Yeon, Hsu, Chiao-Po, Tian, Bin, Pan, Duojia, Sadoshima, Junichi, Del Re, Dominic P

Journal:

Circulation Research

Year:

2016

Language:

english

File:

PDF, 8.23 MB

english, 2016

115

Response by Shirakabe et al to Letter Regarding Article, “Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure”

Shirakabe, Akihiro, Zhai, Peiyong, Ikeda, Yoshiyuki, Saito, Toshiro, Maejima, Yasuhiro, Hsu, Chiao-Po, Nomura, Masatoshi, Egashira, Kensuke, Levine, Beth, Sadoshima, Junichi

Journal:

Year:

2016

Language:

english

File:

PDF, 239 KB

english, 2016

116

Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro

AOKI, Hiroki, RICHMOND, Mary, IZUMO, Seigo, SADOSHIMA, Junichi

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 337 KB

english, 2000

117

H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes

HASE, Makoto, DEPRE, Christophe, VATNER, Stephen F., SADOSHIMA, Junichi

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 911 KB

english, 2005

118

Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro

AOKI, Hiroki, RICHMOND, Mary, IZUMO, Seigo, SADOSHIMA, Junichi

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 337 KB

english, 2000

119

Does Autophagy Mediate Cardiac Myocyte Death During Stress?

Nah, Jihoon, Fernández, Álvaro F., Kitsis, Richard N., Levine, Beth, Sadoshima, Junichi

Journal:

Circulation Research

Year:

2016

Language:

english

File:

PDF, 771 KB

english, 2016

120

Fyn is a Physiological Regulator of Nox4 in the Heart

Matsushima, Shouji, Kinugawa, Shintaro, Tsutsui, Hiroyuki, Sadoshima, Junichi

Journal:

Journal of Cardiac Failure

Year:

2016

Language:

english

File:

PDF, 177 KB

english, 2016

121

GSK3βAlleviates Cardiac Hypertrophy and LV Dysfunction Through Modulation of FoxO1 Transcriptional Activity in Response to Pressure Overload

Maejima, Yasuhiro, Isobe, Mitsuaki, Sadoshima, Junichi

Journal:

Journal of Cardiac Failure

Year:

2016

Language:

english

File:

PDF, 60 KB

english, 2016

122

Nifedipine Negatively Regulates Nox4 and Inhibits HDAC4 Oxidation in Phenylephrine-Induced Cardiac Hypertrophy

Matsushima, Shouji, Matsumoto, Junichi, Kinugawa, Shintaro, Tsutsui, Hiroyuki, Sadoshima, Junichi

Journal:

Journal of Cardiac Failure

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

123

NADPH Oxidase 4 is a Major Source of Mitochondrial Reactive Oxygen Species in the Heart

Matsushima, Shouji, Kinugawa, Shintaro, Sadoshima, Junichi, Tsutsui, Hiroyuki

Journal:

Journal of Cardiac Failure

Year:

2016

Language:

english

File:

PDF, 50 KB

english, 2016

124

Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model

Hsu, Yu-Juei, Hsu, Shih-Che, Hsu, Chiao-Po, Chen, Yen-Hui, Chang, Yung-Lung, Sadoshima, Junichi, Huang, Shih-Ming, Tsai, Chien-Sung, Lin, Chih-Yuan

Journal:

International Journal of Cardiology

Year:

2017

Language:

english

File:

PDF, 2.81 MB

english, 2017

125

Adenylyl Cyclase Type 5 Disruption Prolongs Longevity and Protects the Heart Against Stress

Vatner, Stephen F., Yan, Lin, Ishikawa, Yoshihiro, Vatner, Dorothy E., Sadoshima, Junichi

Journal:

Circulation Journal

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

126

Pathophysiological Roles of NADPH Oxidase/Nox Family Proteins in the Vascular System

Ago, Tetsuro, Kuroda, Junya, Kamouchi, Masahiro, Sadoshima, Junichi, Kitazono, Takanari

Journal:

Circulation Journal

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

127

Regulation of Myocardial Cell Growth and Death by the Hippo Pathway

Ikeda, Shohei, Sadoshima, Junichi

Journal:

Circulation Journal

Year:

2016

Language:

english

File:

PDF, 2.10 MB

english, 2016

128

Modulation of signaling mechanisms in the heart by thioredoxin 1

Nagarajan, Narayani, Oka, Shinichi, Sadoshima, Junichi

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 750 KB

english, 2016

129

Unexpected Functional Consequences of the Loss of the Autophagy-Related Conjugation System

Saito, Toshiro, Sadoshima, Junichi

Journal:

Circulation Research

Year:

2017

Language:

english

File:

PDF, 267 KB

english, 2017

130

A postprandial FGF19‐SHP‐LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy

Byun, Sangwon, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Sadoshima, Junichi, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim

Journal:

The EMBO Journal

Year:

2017

Language:

english

File:

PDF, 9.58 MB

english, 2017

131

Metabolic Reprogramming via PPARα Signaling in Cardiac Hypertrophy and Failure From Metabolomics to Epigenetics

Warren, Junco Shibayama, Oka, Shin-ichi, Zablocki, Daniela, Sadoshima, Junichi

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

132

Guanylyl Cyclase Sensitivity to Nitric Oxide is Protected by a Thiol Oxidation-Driven Interaction with Thioredoxin1

Huang, Can, Alapa, Maryam, Shu, Ping, Nagarajan, Narayan, Wu, Changgong, Sadoshima, Junichi, Kholodovych, Vladyslav, Li, Hong, Beuve, Annie

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

133

Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury

Cao, Yang, Bojjireddy, Naveen, Kim, Maengjo, Li, Tao, Zhai, Peiyong, Nagarajan, Narayani, Sadoshima, Junichi, Palmiter, Richard D, Tian, Rong

Journal:

Circulation Research

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

134

What Should We Learn From the Recent Decline of Basic Cardiovascular Science in Japan?

Sadoshima, Junichi, Tomoike, Hitonobu

Journal:

Circulation Research

Year:

2017

Language:

english

File:

PDF, 614 KB

english, 2017

135

Tyrosine Kinase Fyn Is a Novel Regulator of NADPH Oxidase 4 in Cardiac Remodeling

Matsushima, Shouji, Sadoshima, Junichi, Tsutsui, Hiroyuki

Journal:

Journal of Cardiac Failure

Year:

2017

Language:

english

File:

PDF, 45 KB

english, 2017

136

Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School

Sadoshima, Junichi

Journal:

Circulation Research

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

137

Endogenous HAX-1 Regulates SERCA Activity and Oxidation Dependent Stability

Bidwell, Philip, Liu, Guan-Sheng, Nagarajan, Narayani, Haghighi, Kobra, Gardner, George, Sadoshima, Junichi, Kranias, Evangelia

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2017

Language:

english

File:

PDF, 46 KB

english, 2017

138

Distinct Lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies

Tham, Yow Keat, Huynh, Kevin, Mellett, Natalie A., Henstridge, Darren C., Kiriazis, Helen, Ooi, Jenny Y.Y., Matsumoto, Aya, Patterson, Natalie L., Sadoshima, Junichi, Meikle, Peter J., McMullen, Julie

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2017

Language:

english

File:

PDF, 2.80 MB

english, 2017

139

Key-factors and key-stages that determine the leaf longevity of an evergreen broad-leaved tree, Neolitsea sericea (Lauraceae) at different growing sites in southern Japan

Yukawa, Junichi, Yamamura, Kohji, Fujimoto, Kenji, Tokuda, Makoto, Muroya, Shunichiro, Maki, Tsukasa, Sadoshima, Toshiaki, Fukuda, Takeshi

Journal:

Ecological Research

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

140

New Insights Into the Role of mTOR Signaling in the Cardiovascular System

Sciarretta, Sebastiano, Forte, Maurizio, Frati, Giacomo, Sadoshima, Junichi

Journal:

Circulation Research

Year:

2018

Language:

english

File:

PDF, 2.12 MB

english, 2018

141

Mechanisms responsible for increased circulating levels of galectin-3 in cardiomyopathy and heart failure

Nguyen, My-Nhan, Su, Yidan, Vizi, Donna, Fang, Lu, Ellims, Andris H., Zhao, Wei-Bo, Kiriazis, Helen, Gao, Xiao-Ming, Sadoshima, Junichi, Taylor, Andrew J., McMullen, Julie R., Dart, Anthony M., Kaye,

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.82 MB

english, 2018

142

A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model

Ichimura, Kenzo, Matoba, Tetsuya, Nakano, Kaku, Tokutome, Masaki, Honda, Katsuya, Koga, Jun-ichiro, Egashira, Kensuke, Sadoshima, Junichi

Journal:

Year:

2016

Language:

english

File:

PDF, 3.35 MB

english, 2016

143

Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart

Liu, Ruijie, Khalil, Hadi, Lin, Suh-Chin J., Sargent, Michelle A., York, Allen J., Molkentin, Jeffery D., Sadoshima, Junichi

Journal:

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

144

Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules

Park, Ji Yeon, Li, Wencheng, Zheng, Dinghai, Zhai, Peiyong, Zhao, Yun, Matsuda, Takahisa, Vatner, Stephen F., Sadoshima, Junichi, Tian, Bin, Qin, Gangjian

Journal:

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

145

Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice

Nojima, Aika, Yamashita, Masakatsu, Yoshida, Yohko, Shimizu, Ippei, Ichimiya, Harumi, Kamimura, Naomi, Kobayashi, Yoshio, Ohta, Shigeo, Ishii, Naoaki, Minamino, Tohru, Sadoshima, Junichi

Journal:

Year:

2013

Language:

english

File:

PDF, 1.53 MB

english, 2013

146

Functional Loss of Two Ceramide Synthases Elicits Autophagy-Dependent Lifespan Extension in C. elegans

Mosbech, Mai-Britt, Kruse, Rikke, Harvald, Eva Bang, Olsen, Anne Sofie Braun, Gallego, Sandra Fernandez, Hannibal-Bach, Hans Kristian, Ejsing, Christer S., Færgeman, Nils J., Sadoshima, Junichi

Journal:

Year:

2013

Language:

english

File:

PDF, 749 KB

english, 2013

147

Vascular Endothelium Derived Endothelin-1 Is Required for Normal Heart Function after Chronic Pressure Overload in Mice

Heiden, Susi, Vignon-Zellweger, Nicolas, Masuda, Shigeru, Yagi, Keiko, Nakayama, Kazuhiko, Yanagisawa, Masashi, Emoto, Noriaki, Sadoshima, Junichi

Journal:

Year:

2014

Language:

english

File:

PDF, 3.71 MB

english, 2014

148

Abnormal Mitochondrial L-Arginine Transport Contributes to the Pathogenesis of Heart Failure and Rexoygenation Injury

Williams, David, Venardos, Kylie M., Byrne, Melissa, Joshi, Mandar, Horlock, Duncan, Lam, Nicholas T., Gregorevic, Paul, McGee, Sean L., Kaye, David M., Sadoshima, Junichi

Journal:

Year:

2014

Language:

english

File:

PDF, 883 KB

english, 2014

149

Inhibition of Bcl-2 Sensitizes Mitochondrial Permeability Transition Pore (MPTP) Opening in Ischemia-Damaged Mitochondria

Chen, Qun, Xu, Haishan, Xu, Aijun, Ross, Thomas, Bowler, Elizabeth, Hu, Ying, Lesnefsky, Edward J., Sadoshima, Junichi

Journal:

Year:

2015

Language:

english

File:

PDF, 514 KB

english, 2015

150

The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling

Stein, Adam B., Goonewardena, Sascha N., Jones, Thomas A., Prusick, Parker J., Bazzi, Ahmad A., Belyavskaya, Jane M., McCoskey, Makayla M., Dandar, Rachel A., Sadoshima, Junichi

Journal:

Year:

2015

Language:

english

File:

PDF, 3.80 MB

english, 2015