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1

[AAPS Advances in the Pharmaceutical Sciences Series] The Science and Regulations of Naturally Derived Complex Drugs Volume 32 || Traditional Chinese Medicine Herbal Drugs: From Heritage to Future Developments

Sasisekharan, Ram, Lee, Sau L., Rosenberg, Amy, Walker, Larry A.

Year:

2019

Language:

english

File:

PDF, 594 KB

english, 2019

2

Glycomics: an integrated systems approach to structure-function relationships of glycans

Raman, Rahul, Raguram, S, Venkataraman, Ganesh, Paulson, James C, Sasisekharan, Ram

Journal:

Year:

2005

Language:

english

File:

PDF, 299 KB

english, 2005

3

Process simulation for recombinant protein production: Cost estimation and sensitivity analysis for heparinase I expressed in Escherichia coli

Steffen Ernst, Oscar A. Garro, Stefan Winkler, Ganesh Venkataraman, Robert Langer, Charles L. Cooney, Ram Sasisekharan

Journal:

Biotechnology and Bioengineering

Year:

1997

Language:

english

File:

PDF, 199 KB

english, 1997

4

Heparin and heparan sulfate: biosynthesis, structure and function

Ram Sasisekharan, Ganesh Venkataraman

Journal:

Current Opinion in Chemical Biology

Year:

2000

Language:

english

File:

PDF, 580 KB

english, 2000

5

Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

Sengupta, Shiladitya, Eavarone, David, Capila, Ishan, Zhao, Ganlin, Watson, Nicki, Kiziltepe, Tanyel, Sasisekharan, Ram

Journal:

Year:

2005

Language:

english

File:

PDF, 488 KB

english, 2005

6

Extrapolating from sequence—the 2009 H1N1 'swine' influenza virus

Soundararajan, Venkataramanan, Tharakaraman, Kannan, Raman, Rahul, Raguram, S, Shriver, Zachary, Sasisekharan, V, Sasisekharan, Ram

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 620 KB

english, 2009

7

Roles of heparan-sulphate glycosaminoglycans in cancer

Sasisekharan, Ram, Shriver, Zachary, Venkataraman, Ganesh, Narayanasami, Uma

Journal:

Nature Reviews Cancer

Year:

2002

Language:

english

File:

PDF, 1011 KB

english, 2002

8

Heparinase III fromFlavobacterium heparinum:Cloning and Recombinant Expression inEscherichia coli

Ranga Godavarti, Matthew Davis, Ganesh Venkataraman, Charles Cooney, Robert Langer, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 232 KB

english, 1996

9

Structural Determinants for Naturally Evolving H5N1 Hemagglutinin to Switch Its Receptor Specificity

Tharakaraman, Kannan, Raman, Rahul, Viswanathan, Karthik, Stebbins, Nathan W., Jayaraman, Akila, Krishnan, Arvind, Sasisekharan, V., Sasisekharan, Ram

Journal:

Year:

2013

Language:

english

File:

PDF, 1.96 MB

english, 2013

10

Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin

Tharakaraman, Kannan, Jayaraman, Akila, Raman, Rahul, Viswanathan, Karthik, Stebbins, Nathan W., Johnson, David, Shriver, Zachary, Sasisekharan, V., Sasisekharan, Ram

Journal:

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

11

Molecular Cloning of the Heparin/Heparan Sulfate Δ4,5 Unsaturated Glycuronidase from Flavobacterium heparinum , Its Recombinant Expression in Escherichia coli , and Biochemical Determination of Its Unique Substrate Specificity †

Myette, James R., Shriver, Zachary, Kiziltepe, Tanyel, McLean, Maitland W., Venkataraman, Ganesh, Sasisekharan, Ram

Journal:

Year:

2002

Language:

english

File:

PDF, 351 KB

english, 2002

12

Heparinase I from Flavobacterium heparinum: The Role of the Cysteine Residue in Catalysis as Probed by Chemical Modification and Site-Directed Mutagenesis

Sasisekharan, Ram, Leckband, Deborah, Godavarti, Ranga, Venkataraman, Ganesh, Cooney, Charles L., Langer, Robert

Journal:

Year:

1995

Language:

english

File:

PDF, 1.87 MB

english, 1995

13

The Sweet Science of Glycobiology: Complex carbohydrates, molecules that are particularly important for communication among cells, are coming under systematic study

Ram Sasisekharan and James R. Myette

Journal:

American Scientist

Year:

2003

Language:

english

File:

PDF, 3.61 MB

english, 2003

14

[AAPS Advances in the Pharmaceutical Sciences Series] The Science and Regulations of Naturally Derived Complex Drugs Volume 32 ||

Sasisekharan, Ram, Lee, Sau L., Rosenberg, Amy, Walker, Larry A.

Year:

2019

Language:

english

File:

PDF, 8.07 MB

english, 2019

15

ChemInform Abstract: Heparin and Heparan Sulfate: Biosynthesis, Structure and Function

Ram Sasisekharan, Ganesh Venkataraman

Journal:

Year:

2001

File:

PDF, 24 KB

2001

16

Multifunctional Nanoscale Platforms for Targeting of the Cancer Cell Immortality Spectrum

Venkataramanan Soundararajan, Kenneth Warnock, Ram Sasisekharan

Journal:

Macromolecular Rapid Communications

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

17

Poly(β-amino ester)s Promote Cellular Uptake of Heparin and Cancer Cell Death

David Berry, David M Lynn, Ram Sasisekharan, Robert Langer

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 714 KB

english, 2004

18

Structural Insights into Biological Roles of Protein-Glycosaminoglycan Interactions

Rahul Raman, V. Sasisekharan, Ram Sasisekharan

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 436 KB

english, 2005

19

Cooperativity in Glycan-Protein Interactions

Rahul Raman, Ram Sasisekharan

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

20

Context-Specific Target Definition in Influenza A Virus Hemagglutinin-Glycan Receptor Interactions

Zachary Shriver, Rahul Raman, Karthik Viswanathan, Ram Sasisekharan

Journal:

Chemistry & Biology

Year:

2009

Language:

english

File:

PDF, 1.85 MB

english, 2009

21

Frontiers in glycomics: Bioinformatics and biomarkers in disease An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11–13, 2006)

Nicolle H. Packer, Claus-Wilhelm von der Lieth, Kiyoko F. Aoki-Kinoshita, Carlito B. Lebrilla, James C. Paulson, Rahul Raman, Pauline Rudd, Ram Sasisekharan, Naoyuki Taniguchi, William S. York

Journal:

Year:

2008

Language:

english

File:

PDF, 287 KB

english, 2008

22

Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass spectrometry

Jonathan R. Behr, Yuri Matsumoto, Forest M. White, Ram Sasisekharan

Journal:

Rapid Communications in Mass Spectrometry

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

23

Nitric oxide modulates hepatocyte growth factor/scatter factor-induced angiogenesis

Shiladitya Sengupta, Lynda A. Sellers, Ermanno Gherardi, Ram Sasisekharan, Tai-Ping D. Fan

Journal:

Year:

2004

Language:

english

File:

PDF, 656 KB

english, 2004

24

Glycans as receptors for influenza pathogenesis

Karthik Viswanathan, Aarthi Chandrasekaran, Aravind Srinivasan, Rahul Raman, V. Sasisekharan, Ram Sasisekharan

Journal:

Glycoconjugate Journal

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

25

Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay

Udayanath Aich, Nia Beckley, Zachary Shriver, Rahul Raman, Karthik Viswanathan, Sven Hobbie, Ram Sasisekharan

Journal:

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

26

10.1038/83263

Sasisekharan, Ram, Keiser, Nishla, Venkataraman, Ganesh, Shriver, Zachary

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 498 KB

english, 2001

27

The sweet side of biomarker discovery

Bosques, Carlos J, Raguram, S, Sasisekharan, Ram

Journal:

Nature Biotechnology

Year:

2006

Language:

english

File:

PDF, 193 KB

english, 2006

28

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin

Chandrasekaran, Aarthi, Srinivasan, Aravind, Raman, Rahul, Viswanathan, Karthik, Raguram, S, Tumpey, Terrence M, Sasisekharan, V, Sasisekharan, Ram

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 688 KB

english, 2008

29

Glycomics: a pathway to a class of new and improved therapeutics

Shriver, Zachary, Raguram, S., Sasisekharan, Ram

Journal:

Nature Reviews Drug Discovery

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

30

Heparinase treatment of bovine smooth muscle cells inhibits fibroblast growth factor-2 binding to fibroblast growth factor receptor but not FGF-2 mediated cellular proliferation

Barbara Natke, Ganesh Venkataraman, Matthew A. Nugent, Ram Sasisekharan

Journal:

Year:

1999

Language:

english

File:

PDF, 271 KB

english, 1999

31

Lipid hydroperoxide stimulates retinal neovascularization in rabbit retina through expression of tumor necrosis factor-a, vascular endothelial growth factor and platelet-derived growth factor

Donald Armstrong, Toshihiko Ueda, Takako Ueda, Ahmad Aljada, Richard Browne, Shohei Fukuda, Robert Spengler, Richard Chou, Mary Hartnett, Peter Buch, Paresh Dandona, Ram Sasisekharan, C. Kathleen Dore

Journal:

Year:

1998

Language:

english

File:

PDF, 971 KB

english, 1998

32

On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans

Ram Sasisekharan, Steffen Ernst, Ganesh Venkataraman

Journal:

Year:

1997

Language:

english

File:

PDF, 990 KB

english, 1997

33

Querying quantitative logic models (Q2LM) to study intracellular signaling networks and cell-cytokine interactions

Melody K. Morris, Zachary Shriver, Ram Sasisekharan, Dr. Douglas A. Lauffenburger

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

34

Harnessing glycomics technologies: Integrating structure with function for glycan characterization

Luke N. Robinson, Charlermchai Artpradit, Rahul Raman, Zachary H. Shriver, Mathuros Ruchirawat, Ram Sasisekharan

Journal:

ELECTROPHORESIS

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

35

Emerging Views of Heparan Sulfate Glycosaminoglycan Structure/Activity Relationships Modulating Dynamic Biological Functions

Zachary Shriver, Dongfang Liu, Ram Sasisekharan

Journal:

Trends in Cardiovascular Medicine

Year:

2002

Language:

english

File:

PDF, 361 KB

english, 2002

36

Carbodiimide modification enhances activity of pig pancreatic phospholipase A2

João Paulo M. FERREIRA, Ram SASISEKHARAN, Otway LOUIE, Robert LANGER

Journal:

Year:

1994

Language:

english

File:

PDF, 579 KB

english, 1994

37

A Comparative Analysis of the Primary Sequences and Characteristics of Heparinases I, II, and III fromFlavobacterium heparinum

Ranga Godavarti, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 106 KB

english, 1996

38

Recombinant Expression, Purification, and Kinetic Characterization of Chondroitinase AC and Chondroitinase B from Flavobacterium heparinum

Kevin Pojasek, Zachary Shriver, Patrick Kiley, Ganesh Venkataraman, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

39

Expression in Escherichia coli, Purification and Kinetic Characterization of Human Heparan Sulfate 3-O-Sulfotransferase-1

James R Myette, Zachary Shriver, Jian Liu, Ganesh Venkataraman, Robert Rosenberg, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

40

Identification of Structural Motifs and Amino Acids within the Structure of Human Heparan Sulfate 3-O-Sulfotransferase That Mediate Enzymatic Function

Rahul Raman, James Myette, Ganesh Venkataraman, V Sasisekharan, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 265 KB

english, 2002

41

Quantitative assessment of FGF regulation by cell surface heparan sulfates

David Berry, Zachary Shriver, Ganesh Venkataraman, Ram Sasisekharan

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 185 KB

english, 2004

42

Heparin localization and fine structure regulate Burkitt’s lymphoma growth

David Berry, David M. Lynn, Eric Berry, Ram Sasisekharan, Robert Langer

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 188 KB

english, 2006

43

Heparanase, heparin and the coagulation system in cancer progression

Israel Vlodavsky, Neta Ilan, Yona Nadir, Benjamin Brenner, Ben-Zion Katz, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Ram Sasisekharan

Journal:

Thrombosis Research

Year:

2007

Language:

english

File:

PDF, 309 KB

english, 2007

44

GLYCOMICS APPROACH TO STRUCTURE-FUNCTION RELATIONSHIPS OF GLYCOSAMINOGLYCANS

Sasisekharan, Ram, Raman, Rahul, Prabhakar, Vikas

Journal:

Annual Review of Biomedical Engineering

Year:

2006

Language:

english

File:

PDF, 825 KB

english, 2006

45

Heparin sensing: Blue-chip binding

Shriver, Zachary, Sasisekharan, Ram

Journal:

Nature Chemistry

Year:

2013

Language:

english

File:

PDF, 193 KB

english, 2013

46

Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets

Lakdawala, Seema S., Shih, Angela R., Jayaraman, Akila, Lamirande, Elaine W., Moore, Ian, Paskel, Myeisha, Sasisekharan, Ram, Subbarao, Kanta

Journal:

Year:

2013

Language:

english

File:

PDF, 5.45 MB

english, 2013

47

Modular glycosphere assays for high-throughput functional characterization of influenza viruses

Hobbie, Sven N, Viswanathan, Karthik, Bachelet, Ido, Aich, Udayanath, Shriver, Zachary, Subramanian, Vidya, Raman, Rahul, Sasisekharan, Ram

Journal:

BMC Biotechnology

Year:

2013

Language:

english

File:

PDF, 518 KB

english, 2013

48

Broadly Neutralizing Influenza Hemagglutinin Stem-Specific Antibody CR8020 Targets Residues that Are Prone to Escape due to Host Selection Pressure

Tharakaraman, Kannan, Subramanian, Vidya, Cain, David, Sasisekharan, Viswanathan, Sasisekharan, Ram

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 1.64 MB

english, 2014

49

Recognition of heparan sulfate by clinical strains of dengue virus serotype 1 using recombinant subviral particles

Artpradit, Charlermchai, Robinson, Luke N., Gavrilov, Boris K., Rurak, Troy T., Ruchirawat, Mathuros, Sasisekharan, Ram

Journal:

Year:

2013

Language:

english

File:

PDF, 961 KB

english, 2013

50

Insights into the Human Glycan Receptor Conformation of 1918 Pandemic Hemagglutinin–Glycan Complexes Derived from Nuclear Magnetic Resonance and Molecular Dynamics Studies

Elli, Stefano, Macchi, Eleonora, Rudd, Timothy R., Raman, Rahul, Sassaki, Guillherme, Viswanathan, Karthik, Yates, Edwin A., Shriver, Zachary, Naggi, Annamaria, Torri, Giangiacomo, Sasisekharan, Ram,

Journal:

Year:

2014

Language:

english

File:

PDF, 3.50 MB

english, 2014

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