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1

Anticoagulant Therapy with the Oral Direct Factor Xa Inhibitors Rivaroxaban, Apixaban and Edoxaban and the Thrombin Inhibitor Dabigatran Etexilate in Patients with Hepatic Impairment

Jochen Graff, Sebastian Harder

Journal:

Clinical Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 456 KB

english, 2013

2

Using ImageJ for the quantitative analysis of flow-based adhesion assays in real-time under physiologic flow conditions

Meyer dos Santos, Sascha, Klinkhardt, Ute, Schneppenheim, Reinhard, Harder, Sebastian

Journal:

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

3

Terson haemorrhage in patients suffering aneurysmal subarachnoid haemorrhage: A prospective analysis of 60 consecutive patients

Martin N. Stienen, Sebastian Lücke, Oliver P. Gautschi, Albrecht Harders

Journal:

Clinical Neurology and Neurosurgery

Year:

2012

Language:

english

File:

PDF, 232 KB

english, 2012

4

Risk of hyperkalemia and combined use of spironolactone and long-term ACE inhibitor/angiotensin receptor blocker therapy in heart failure using real-life data: a population- and insurance-based cohort

Abbas, Sascha, Ihle, Peter, Harder, Sebastian, Schubert, Ingrid

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2015

Language:

english

File:

PDF, 109 KB

english, 2015

5

Breast carcinoma during pregnancy : International recommendations from an expert meeting

Sibylle Loibl, Gunter von Minckwitz, Karin Gwyn, Paul Ellis, Jens U. Blohmer, Brigitte Schlegelberger, Monika Keller, Sebastian Harder, Richard L. Theriault, Diana Crivellari, Thomas Klingebiel, Frank

Journal:

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

6

Single dose and steady state pharmacokinetics and pharmacodynamics of the ACE-inhibitor imidapril in hypertensive patients

Sebastian Harder, Petra A. Thürmann, Wolfram Ungethüm

Journal:

British Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 88 KB

english, 1998

7

Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves

Stefan W. Toennes, Sebastian Harder, Markus Schramm, Constanze Niess, Gerold F. Kauert

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

8

Die Entlassungsmedikation im Arztbrief

Angela Roth-Isigkeit, Sebastian Harder

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

2005

Language:

german

File:

PDF, 249 KB

german, 2005

9

Effects of grapefruit juice and smoking on verapamil concentrations in steady state

Uwe Fuhr, Herbert Müller-Peltzer, Rainer Kern, Pablo Lopez-Rojas, Manfred Jünemann, Sebastian Harder, Horst A. Staib

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 146 KB

english, 2002

10

XML indexing and storage: fulfilling the wish list

Mathis, Christian, Härder, Theo, Schmidt, Karsten, Bächle, Sebastian

Journal:

Computer Science - Research and Development

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

11

Clinically Important Drug Interactions with Anticoagulants

Dr med. Sebastian Harder,Petra Thürmann

Journal:

Clinical Pharmacokinetics

Year:

1996

Language:

english

File:

PDF, 4.54 MB

english, 1996

12

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures

Skarke, Carsten, Kuczka, Karina, Tausch, Lars, Werz, Oliver, Rossmanith, Tanja, Barrett, Jeffrey S., Harder, Sebastian, Holtmeier, Wolfgang, Schwarz, Joachim A.

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 805 KB

english, 2012

13

Achieving hard X-ray nanofocusing using a wedged multilayer Laue lens

Huang, Xiaojing, Conley, Raymond, Bouet, Nathalie, Zhou, Juan, Macrander, Albert, Maser, Jorg, Yan, Hanfei, Nazaretski, Evgeny, Lauer, Kenneth, Harder, Ross, Robinson, Ian K., Kalbfleisch, Sebastian,

Journal:

Year:

2015

Language:

english

File:

PDF, 3.08 MB

english, 2015

14

Anti-GPVI Fab SAR264565 effectively blocks GPVI function in ex vivo human platelets under arterial shear in a perfusion chamber

Florian, Peter, Wonerow, Peter, Harder, Sebastian, Kuczka, Karina, Dubar, Michel, Graff, Jochen

Journal:

European Journal of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 611 KB

english, 2017

15

Direct oral anticoagulants for the treatment of venous thromboembolism in cancer patients: Potential for drug–drug interactions

Riess, Hanno, Prandoni, Paolo, Harder, Sebastian, Kreher, Stephan, Bauersachs, Rupert

Journal:

Critical Reviews in Oncology/Hematology

Year:

2018

Language:

english

File:

PDF, 533 KB

english, 2018

16

Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone Induced Cardiac Hypertrophy and Pyrexia

Herrmann, Beate, Harder, Lisbeth, Oelkrug, Rebecca, Chen, Jiesi, Gachkar, Sogol, Nock, Sebastian, Resch, Julia, Korkowski, Markus, Heuer, Heike, Mittag, Jens

Journal:

Year:

2020

Language:

english

File:

PDF, 1.87 MB

english, 2020

17

Helicobacter pylori infection and polymorphisms in the tumor necrosis factor region

Erdmute Kunstmann, Cornelia Epplen, Ercan Elitok, Marianne Harder, Sebastian Suerbaum, Ulrich Peitz, Wolff Schmiegel, Jörg T. Epplen

Journal:

ELECTROPHORESIS

Year:

1999

Language:

english

File:

PDF, 123 KB

english, 1999

18

Fully automatic geometry planning for cardiac MR imaging and reproducibility of functional cardiac parameters

Michael Frick, Ingo Paetsch, Chiel den Harder, Marc Kouwenhoven, Harald Heese, Sebastian Dries, Bernhard Schnackenburg, Wendy de Kok, Rolf Gebker, Eckart Fleck, Robert Manka, Cosima Jahnke

Journal:

Journal of Magnetic Resonance Imaging

Year:

2011

Language:

english

File:

PDF, 936 KB

english, 2011

19

Concentration-response relationship of levodopa in patients at different stages of Parkinson's disease *

Harder, Sebastian, Baas, Horst

Journal:

Clinical Pharmacology & Therapeutics

Year:

1998

Language:

english

File:

PDF, 913 KB

english, 1998

20

Pharmacodynamic characterization of the interaction between abciximab or tirofiban with unfractionated or a low molecular weight heparin in healthy subjects

Ute Klinkhardt, Jochen Graff, Dagmar Westrup, Carl M. Kirchmaier, Hans-Ulrich Esslinger, Hans Klaus Breddin, Sebastian Harder

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 161 KB

english, 2001

21

Pharmacodynamic characterization of the interaction between the glycoprotein IIb/IIIa inhibitor YM337 and unfractionated heparin and aspirin in humans

Jochen Graff, Ute Klinkhardt, Dagmar Westrup, Carl M. Kirchmaier, Hans Klaus Breddin, Sebastian Harder

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

22

Pharmacokinetic and pharmacodynamic interaction trial after repeated oral doses of imdapril and digoxin in healthy volunteers

Sebastian Harder, Petra A. Thürmann

Journal:

British Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 372 KB

english, 1997

23

Interaction between the LMWH reviparin and aspirin in healthy volunteers

Ute Klinkhardt,, Hans Klaus Breddin,, Heinz Ulrich Esslinger,, Silvia Haas, Andreas Kalatzis, Sebastian Harder

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 91 KB

english, 2000

24

Angiotensin II infusion increases plasma erythropoietin levels via an angiotensin II type 1 receptor-dependent pathway

Gossmann, Jan, Burkhardt, Ralf, Harder, Sebastian, Lenz, Tomas, Sedlmeyer, Annette, Klinkhardt, Ute, Geiger, Helmut, Scheuermann, Ernst-Heinrich

Journal:

Kidney International

Year:

2001

Language:

english

File:

PDF, 101 KB

english, 2001

25

Antikoagulanzien im Überblick: Gestern, heute und morgen

Sebastian Harder, Hans Klaus Breddin

Journal:

Pharmazie in unserer Zeit

Year:

2004

Language:

german

File:

PDF, 732 KB

german, 2004

26

Struktur und Aktivitäten von Arzneimittelkommissionen in Deutschland

Sebastian Harder, Petra Thürmann, Andrea Steioff, Studiengruppe „Pharmakoökonomie und rationale Arzneimitteltherapie” der Deutschen Gesellschaft für Klinische Pharmakologie und Therapie

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

1998

Language:

german

File:

PDF, 831 KB

german, 1998

27

Dosis-Wirkungs-Beziehung: Relevanz für die ärztliche Praxis

Ute Klinkhardt, Sebastian Harder

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

1998

File:

PDF, 643 KB

1998

28

Professor Norbert H. Rietbrock

Uwe Fuhr, Sebastian Harder, Brigitte Keller-Stanislawski, Petra Thürmann, Verbund Klinische Pharmakologie in Deutschland

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

29

Structure and markers of appropriateness, quality and performance of drug treatment over a 1-year period after hospital discharge in a cohort of elderly patients with cardiovascular diseases from Germany

Sebastian Harder, Philipp Fischer, Markus Krause-Schäfer, Klaus Ostermann, Gottfried Helms, Helge Prinz, Mike Hahmann, Horst Baas

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

30

Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults

Nils von Hentig, Brenda Dauer, Annette Haberl, Stefan Klauke, Thomas Lutz, Schlomo Staszewski, Sebastian Harder

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

31

Professor Dr. Nina Bakracheva

Petra A. Thürmann, Emil Gatchev, Uwe Fuhr, Sebastian Harder

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

32

„Von der Torfabrik zur Denkfabrik“ Bericht zur 14. Fachtagung „Datenbanksysteme für Business, Technologie und Web“

Sebastian Bächle, Theo Härder, Volker Höfner, Joachim Klein, Yi Ou, Steffen Reithermann, Daniel Schall, Karsten Schmidt, Andreas Weiner

Journal:

Datenbank-Spektrum

Year:

2011

Language:

german

File:

PDF, 728 KB

german, 2011

33

Pharmacokinetics of trapidil, an antagonist of platelet derived growth factor, in healthy subjects and in patients with liver cirrhosis

SEBASTIAN HARDER, PETRA A. THÜRMANN, ANTON HELLSTERN, ANNA BENJAMINOV

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 292 KB

english, 1996

34

A comparison of the steady-state pharmacokinetics of nevirapine in men, nonpregnant women and women in late pregnancy

Nils Von Hentig, Amina Carlebach, Peter Gute, Gaby Knecht, Stefan Klauke, Maren Rohrbacher, Hartmut Stocker, Michael Kurowski, Sebastian Harder, Schlomo Staszewski, Annette Haberl

Journal:

British Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

35

Anticoagulation with argatroban in patients with heparin-induced thrombocytopenia antibodies after cardiovascular surgery with cardiopulmonary bypass: First results from the ARG-E03 trial

Andreas Koster, Semi Buz, Roland Hetzer, Hermann Kuppe, Klaus Breddin, Sebastian Harder

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2006

Language:

english

File:

PDF, 76 KB

english, 2006

36

Argatroban anticoagulation for renal replacement therapy in patients with heparin-induced thrombocytopenia after cardiovascular surgery

Andreas Koster, Thomas Hentschel, Tom Groman, Hermann Kuppe, Roland Hetzer, Sebastian Harder, Karl-Georg Fischer

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

37

Ciprofloxacin-caffeine: A drug interaction established using in vivo and in vitro investigations

Sebastian Harder, Uwe Fuhr, A. Horst Staib, Thomas Wolff

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 378 KB

english, 1989

38

Absorption differences of ciprofloxacin along the human gastrointestinal tract determined using a remote-control drug delivery device (HF-capsule)

A. Horst Staib, Dieter Beermann, Sebastian Harder, Uwe Fuhr, Dieter Liermann

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 410 KB

english, 1989

39

The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line

Igor Tsaur, Jasmina Makarević, Lukasz Hudak, Eva Juengel, Martin Kurosch, Christoph Wiesner, Georg Bartsch, Sebastian Harder, Axel Haferkamp, Roman A. Blaheta

Journal:

Year:

2011

Language:

english

File:

PDF, 434 KB

english, 2011

40

Effects of the NHE-1 inhibitor cariporide alone or together with the P2Y12 antagonist AR-C 69331 MX on CD62p expression and formation of platelet–leukocyte aggregates

Ute Klinkhardt, Karina Kuczka, Sebastian Harder

Journal:

Thrombosis Research

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

41

Pharmacodynamic profile of antiplatelet agents: marked differences between single versus costimulation with platelet activators

Jochen Graff, Ute Klinkhardt, Sebastian Harder

Journal:

Thrombosis Research

Year:

2004

Language:

english

File:

PDF, 249 KB

english, 2004

42

Monitoring direct FXa-inhibitors and fondaparinux by Prothrombinase-induced Clotting Time (PiCT): Relation to FXa-activity and influence of assay modifications

Sebastian Harder, Jeannine Parisius, Bettina Picard-Willems

Journal:

Thrombosis Research

Year:

2008

Language:

english

File:

PDF, 404 KB

english, 2008

43

Phenotypic differences of human neutrophils of carriers of the PSGL-1 A and B-allele in binding to immobilised P-selectin under flow conditions

Sascha Meyer dos Santos, Ute Klinkhardt, Katharina Lang, Jeannine Parisius, Karina Kuczka, Sebastian Harder

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

44

Differential in Vitro Effects of the Platelet Glycoprotein IIb/IIIa Inhibitors abixicimab or SR121566A on Platelet Aggregation, Fibrinogen Binding and Platelet Secretory Parameters

Ute Klinkhardt, Carl M Kirchmaier, Dagmar Westrup, Hans Klaus Breddin, Rene Mahnel, Jochen Graff, Monika Hild, Sebastian Harder

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

45

Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: A double-blind, randomized, parallel-group study

Jochen Graff, Mohammed Arabmotlagh, Raymond Cheung, Gerd Geisslinger, Sebastian Harder

Journal:

Clinical Therapeutics

Year:

2007

Language:

english

File:

PDF, 805 KB

english, 2007

46

Inhibition of endothelial receptor expression and of T-cell ligand activity by mycophenolate mofetil

Roman A Blaheta, Kerstin Leckel, Bianca Wittig, Dietmar Zenker, Elsie Oppermann, Sebastian Harder, Martin Scholz, Stephan Weber, Horst Schuldes, Albrecht Encke, Bernd H Markus

Journal:

Transplant Immunology

Year:

1998

Language:

english

File:

PDF, 961 KB

english, 1998

47

Biomarkers and Coagulation Tests for Assessing the Biosimilarity of a Generic Low-Molecular-Weight Heparin: Results of a Study in Healthy Subjects With Enoxaparin

Kuczka, Karina, Harder, Sebastian, Picard-Willems, Bettina, Warnke, André, Donath, Frank, Bianchini, Pietro, Parma, Bruna, Blume, Henning

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008

48

Induction of central signalling pathways and select functional effects in human platelets by β-boswellic acid

Daniel Poeckel, Lars Tausch, Anja Altmann, Christian Feißt, Ute Klinkhardt, Jochen Graff, Sebastian Harder, Oliver Werz

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 386 KB

english, 2005

49

Primary care management for optimized antithrombotic treatment [PICANT]: study protocol for a cluster-randomized controlled trial

Andrea Siebenhofer, Lisa R Ulrich, Karola Mergenthal, Ina Roehl, Sandra Rauck, Andrea Berghold, Sebastian Harder, Ferdinand M Gerlach, Juliana J Petersen

Journal:

Implementation Science

Year:

2012

Language:

english

File:

PDF, 187 KB

english, 2012

50

Thrombolytics

Dr Sebastian Harder, Ute Klinkhardt

Journal:

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000