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1

Measurement of Molecular Weight Distribution of Hyaluronic Acid by Size Exclusion Chromatography Using Low-angle Laser Light Scattering.

Shibutani, Mitsuru, Oishi, Taeko, Yamamoto, Shinya, Hasebe, Susumu

Journal:

Journal of Society of Cosmetic Chemists of Japan

Year:

1998

File:

PDF, 569 KB

1998

2

Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate

Yoshinori Okamoto, Xiaoping Liu, Naomi Suzuki, Kanako Okamoto, Masashi Sekimoto, Y.R. Santosh Laxmi, Shinya Shibutani

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 164 KB

english, 2008

3

Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents

Shinya Shibutani, Radha R. Bonala, Thomas Rosenquist, Robert Rieger, Naomi Suzuki, Francis Johnson, Frederick Miller, Arthur P. Grollman

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 421 KB

english, 2010

4

Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions

Y.R. Santosh Laxmi, Xiaoping Liu, Naomi Suzuki, Sung Yeon Kim, Kanako Okamoto, Hyo Jeong Kim, Guangxiang Zhang, John J. Chen, Yoshinori Okamoto, Shinya Shibutani

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 660 KB

english, 2010

5

Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen

Naomi Suzuki, Xiaoping Liu, Y. R. Santosh Laxmi, Kanako Okamoto, Hyo Jeong Kim, Guangxiang Zhang, John J. Chen, Yoshinori Okamoto, Shinya Shibutani

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 608 KB

english, 2011

6

Synthesis of oligodeoxynucleotides containing a single diastereoisomer of α-(N2-2′-deoxyguanosinyl)-N-desmethyltamoxifen

Y.R Santosh Laxmi, Naomi Suzuki, Sung Yeon Kim, Shinya Shibutani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 283 KB

english, 2004

7

Lymphoscintigraphy for sentinel lymph node mapping in Japanese patients with malignant skin neoplasms of the lower extremities: comparison with previously investigated Japanese lymphatic anatomy

Hiroyuki Miura, Shuichi Ono, Morio Nagahata, Koichi Shibutani, Shinya Kakehata, Kohei Morimoto, Hiroko Seino, Akihisa Kakuta, Masahiko Aoki, Yoshiomi Hatayama, Hideo Kawaguchi, Yoshihiro Takai, Yoshin

Journal:

Annals of Nuclear Medicine

Year:

2010

Language:

english

File:

PDF, 290 KB

english, 2010

8

DNA damage and altered gene expression of enzymes for metabolism and DNA repair by tamoxifen and toremifene in the female rat liver

Masamichi Hashiba, Toshihiko Kasahara, Sung Yeon Kim, Shinya Shibutani, Masakuni Degawa

Journal:

Year:

2006

Language:

english

File:

PDF, 345 KB

english, 2006

9

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

Shibutani, Shinya, Takeshita, Masaru, Grollman, Arthur P.

Journal:

Year:

1991

File:

PDF, 647 KB

1991

10

Mutagenic Properties of Estrogen Quinone-Derived DNA Adducts in Simian Kidney Cells†

Terashima, Isamu, Suzuki, Naomi, Shibutani, Shinya

Journal:

Year:

2001

Language:

english

File:

PDF, 189 KB

english, 2001

11

Determination of Tamoxifen−DNA Adducts in Leukocytes from Breast Cancer Patients Treated with Tamoxifen

Umemoto, Atsushi, Monden, Yasumasa, Lin, Chun-Xing, Momen, Md. Abdul, Ueyama, Yuji, Komaki, Kansei, Laxmi, Y. R. Santosh, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

12

Mutagenic specificity of 2-acetylaminonaphthalene-derived DNA adduct in mammalian cells

Xingzhi Tan, Radha-Rani Bonala, Naomi Suzuki, Francis Johnson, Arthur P. Grollman, Shinya Shibutani

Journal:

Chemico-Biological Interactions

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005

13

Molecular mechanisms of mutagenesis by aromatic amines and amides

Shinya Shibutani, Arthur P. Grollman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 227 KB

english, 1997

14

Productivity of concentrated hyaluronic acid using a Maxblend® fermentor

Shuji Hasegawa, Masanori Nagatsuru, Mitsuru Shibutani, Shinya Yamamoto, Susumu Hasebe

Journal:

Journal of Bioscience and Bioengineering

Year:

1999

Language:

english

File:

PDF, 446 KB

english, 1999

15

Tamoxifen−DNA Adducts Detected in the Endometrium of Women Treated with Tamoxifen†

Shibutani, Shinya, Suzuki, Naomi, Terashima, Isamu, Sugarman, Steven M., Grollman, Arthur P., Pearl, Michael L.

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 98 KB

english, 1999

16

In situ detection of acetylaminofluorene–DNA adducts in human cells using monoclonal antibodies

Taka-aki Iwamoto, Nobuhiko Kobayashi, Kyoko Imoto, Aya Yamamoto, Yu Nakamura, Yukika Yamauchi, Hiromi Okumura, Akiko Tanaka, Fumio Hanaoka, Shinya Shibutani, Sachiko Miyagawa, Toshio Mori

Journal:

Year:

2004

Language:

english

File:

PDF, 179 KB

english, 2004

17

Translesion Synthesis past 2′-Deoxyxanthosine, a Nitric Oxide-derived DNA Adduct, by Mammalian DNA Polymerases

Manabu Yasui, Naomi Suzuki, Holly Miller, Tomonari Matsuda, Saburo Matsui, Shinya Shibutani

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 295 KB

english, 2004

18

Mechanism of Translesion Synthesis Past an Equine Estrogen-DNA Adduct by Y-Family DNA Polymerases

Manabu Yasui, Naomi Suzuki, Xiaoping Liu, Yoshinori Okamoto, Sung Yeon Kim, Y.R. Santosh Laxmi, Shinya Shibutani

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 860 KB

english, 2007

19

Miscoding Properties of 2′-Deoxyinosine, a Nitric Oxide-Derived DNA Adduct, during Translesion Synthesis Catalyzed by Human DNA Polymerases

Manabu Yasui, Emi Suenaga, Naoki Koyama, Chikahide Masutani, Fumio Hanaoka, Petr Gruz, Shinya Shibutani, Takehiko Nohmi, Makoto Hayashi, Masamitsu Honma

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 651 KB

english, 2008

20

Anti-breast cancer potential of daidzein in rodents

Xiaoping Liu, Naomi Suzuki, Y.R. Santosh Laxmi, Yoshinori Okamoto, Shinya Shibutani

Journal:

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

21

Equine estrogen-induced mammary tumors in rats

Yoshinori Okamoto, Xiaoping Liu, Naomi Suzuki, Kanako Okamoto, Hyo Jeong Kim, Y.R. Santosh Laxmi, Kazutoshi Sayama, Shinya Shibutani

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

22

Synthesis of Oligodeoxynucleotides Containing a Single 6α- or 6β-Diastereoisomer of N 2 -(Estradiol-6-yl)-2‘-deoxyguanosine

Itoh, Shinji, Shibutani, Shinya, Ikegami, Masazumi, Watanabe, Shingo, Laxmi, Y. R. Santosh, Suzuki, Naomi, Kohda, Kohfuku, Takanashi, Kaori, Yoshizawa, Itsuo

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

23

Identification of Estrogen-Modified Nucleosides from Calf Thymus DNA Reacted with 6-Hydroxyestrogen 6-Sulfates

Itoh, Shinji, Hirai, Toshiaki, Totsuka, Yukari, Takagi, Hidetoshi, Tashiro, Yumiko, Wada, Koji, Wakabayashi, Keiji, Shibutani, Shinya, Yoshizawa, Itsuo

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

24

Translesion Synthesis Past Tamoxifen-Derived DNA Adducts by Human DNA Polymerases η and κ †

Yasui, Manabu, Suzuki, Naomi, Laxmi, Y. R. Santosh, Shibutani, Shinya

Journal:

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

25

Miscoding Properties of 6α- and 6β-Diastereoisomers of the N 2 -(Estradiol-6-yl)-2′-deoxyguanosine DNA Adduct by Y-Family Human DNA Polymerases †

Poon, Kinning, Itoh, Shinji, Suzuki, Naomi, Laxmi, Y. R. Santosh, Yoshizawa, Itsuo, Shibutani, Shinya

Journal:

Year:

2008

Language:

english

File:

PDF, 2.89 MB

english, 2008

26

Identification of Tamoxifen−DNA Adducts Formed by α-Sulfate Tamoxifen and α-Acetoxytamoxifen

Dasaradhi, Lakkaraju, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 618 KB

english, 1997

27

Synthesis of 2'-deoxy-7,8-dihydro-8-oxoguanosine and 2'-deoxy-7,8-dihydro-8-oxoadenosine and their incorporation into oligomeric DNA

Bodepudi, Veeraiah, Shibutani, Shinya, Johnson, Francis

Journal:

Chemical Research in Toxicology

Year:

1992

Language:

english

File:

PDF, 1.18 MB

english, 1992

28

Water-soluble Polyvinyl Alcohol Microspheres for Temporary Embolization: Development and in Vivo Characteristics in a Pig Kidney Model

Shomura, Yuzo, Tanigawa, Noboru, Shibutani, Mitsuo, Wakimoto, Shinya, Tsuji, Kazutoshi, Tokuda, Takanori, Terada, Jiro, Kariya, Shuji, Kojima, Hiroyuki, Komemushi, Atsushi, Sawada, Satoshi

Journal:

Journal of Vascular and Interventional Radiology

Year:

2011

Language:

english

File:

PDF, 1.72 MB

english, 2011

29

Miscoding during DNA synthesis on damaged DNA templates catalysed by mammalian cell extracts

Shibutani, Shinya, Grollman, Arthur P.

Journal:

Year:

1994

Language:

english

File:

PDF, 772 KB

english, 1994

30

Proliferating Cell Nuclear Antigen Promotes DNA Synthesis Past Template Lesions by Mammalian DNA Polymerase δ

Dmitry Ju. Mozzherin, Shinya Shibutani, Cheng-Keat Tan, Kathleen M. Downey and Paul A. Fisher

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.34 MB

english, 1997

31

Miscoding Potential of the N 2 -Ethyl-2‘-deoxyguanosine DNA Adduct by the Exonuclease-Free Klenow Fragment of Escherichia coli DNA Polymerase I †

Terashima, Isamu, Matsuda, Tomonari, Fang, Tzan-Wei, Suzuki, Naomi, Kobayashi, Jun, Kohda, Kohfuku, Shibutani, Shinya

Journal:

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

32

Oxidative DNA Damage in XPC -Knockout and Its Wild Mice Treated with Equine Estrogen

Okamoto, Yoshinori, Chou, Pei-Hsin, Kim, Sung Yeon, Suzuki, Naomi, Laxmi, Y. R. Santosh, Okamoto, Kanako, Liu, Xiaoping, Matsuda, Tomonari, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

33

Lifetime and Reactivity of an Ultimate Tamoxifen Carcinogen: The Tamoxifen Carbocation

Sanchez, Cristina, Shibutani, Shinya, Dasaradhi, Lakkaraju, Bolton, Judy L., Fan, Peter W., McClelland, Robert A.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 61 KB

english, 1998

34

Mutagenic Potential of Benzo[ a ]pyrene-Derived DNA Adducts Positioned in Codon 273 of the Human P53 Gene †

Dong, Huan, Bonala, Radha Rani, Suzuki, Naomi, Johnson, Francis, Grollman, Arthur P., Shibutani, Shinya

Journal:

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

35

Translesion Synthesis past Equine Estrogen-Derived 2‘-Deoxycytidine DNA Adducts by Human DNA Polymerases η and κ †

Suzuki, Naomi, Yasui, Manabu, Santosh Laxmi, Y. R., Ohmori, Haruo, Hanaoka, Fumio, Shibutani, Shinya

Journal:

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

36

Preparation of Oligodeoxynucleotides Containing a Diastereoisomer of α-( N 2 -2‘-Deoxyguanosinyl)tamoxifen by Phosphoramidite Chemical Synthesis

Santosh Laxmi, Y. R., Suzuki, Naomi, Dasaradhi, Lakkaraju, Johnson, Francis, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

37

Synthesis, Miscoding Specificity, and Thermodynamic Stability of Oligodeoxynucleotide Containing 8-Methyl-2‘-deoxyguanosine

Kohda, Kohfuku, Tsunomoto, Hirotaka, Minoura, Yasushi, Tanabe, Kazushi, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 415 KB

english, 1996

38

Translesional Synthesis on DNA Templates Containing an Estrogen Quinone-Derived Adduct: N 2 -(2-Hydroxyestron-6-yl)-2‘-deoxyguanosine and N 6 -(2-Hydroxyestron-6-yl)-2‘-deoxyadenosine †

Terashima, Isamu, Suzuki, Naomi, Dasaradhi, Lakkaraju, Tan, Cheng-Keat, Downey, Kathleen M., Shibutani, Shinya

Journal:

Year:

1998

Language:

english

File:

PDF, 228 KB

english, 1998

39

32 P-Postlabeling/Polyacrylamide Gel Electrophoresis Analysis: Application to the Detection of DNA Adducts

Terashima, Isamu, Suzuki, Naomi, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

40

Translesional synthesis on DNA templates containing 8-oxo-7,8-dihydrodeoxyadenosine

Shibutani, Shinya, Bodepudi, Veeraiah, Johnson, Francis, Grollman, Arthur P.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.58 MB

english, 1993

41

Miscoding Properties of 3 ,N 4 -Etheno-2‘-deoxycytidine in Reactions Catalyzed by Mammalian DNA Polymerases †

Shibutani, Shinya, Suzuki, Naomi, Matsumoto, Yoshihiro, Grollman, Arthur P.

Journal:

Year:

1996

Language:

english

File:

PDF, 602 KB

english, 1996

42

Mutagenic Events in Escherichia coli and Mammalian Cells Generated in Response to Acetylaminofluorene-Derived DNA Adducts Positioned in the Nar I Restriction Enzyme Site †

Tan, Xingzhi, Suzuki, Naomi, Grollman, Arthur P., Shibutani, Shinya

Journal:

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

43

Mutagenic Specificity of Model Estrogen−DNA Adducts in Mammalian Cells †

Terashima, Isamu, Suzuki, Naomi, Itoh, Shinji, Yoshizawa, Itsuo, Shibutani, Shinya

Journal:

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

44

Translesion Synthesis Past Equine Estrogen-Derived 2‘-Deoxyadenosine DNA Adducts by Human DNA Polymerases η and κ †

Yasui, Manabu, Laxmi, Y. R. Santosh, Ananthoju, Sreenivasa R., Suzuki, Naomi, Kim, Sung Yeon, Shibutani, Shinya

Journal:

Year:

2006

Language:

english

File:

PDF, 220 KB

english, 2006

45

Synthesis and Miscoding Specificity of Oligodeoxynucleotide Containing 8-Phenyl-2‘-deoxyguanosine

Kohda, Kohfuku, Tsunomoto, Hirotaka, Kasamatsu, Toshio, Sawamura, Fumiko, Terashima, Isamu, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

46

Tamoxifen−DNA Adducts Formed by α-Acetoxytamoxifen N -Oxide †

Umemoto, Atsushi, Monden, Yasumasa, Komaki, Kansei, Suwa, Masato, Kanno, Yoshikazu, Suzuki, Masanobu, Lin, Chun-Xing, Ueyama, Yuji, Momen, Md. Abdul, Ravindernath, Anisetti, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 221 KB

english, 1999

47

NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).cntdot.dA(anti) alignment at lesion site

Kouchakdjian, Michael, Bodepudi, Veeraiah, Shibutani, Shinya, Eisenberg, Moises, Johnson, Francis, Grollman, Arthur P., Patel, Dinshaw J.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.07 MB

english, 1991

48

Translesion Synthesis Past Estrogen-Derived DNA Adducts by Human DNA Polymerases η and κ †

Suzuki, Naomi, Itoh, Shinji, Poon, Kinning, Masutani, Chikahide, Hanaoka, Fumio, Ohmori, Haruo, Yoshizawa, Itsuo, Shibutani, Shinya

Journal:

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

49

Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7, 8-dihydroxy-anti-9, 10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

Shibutani, Shinya, Margulis, Leonid A., Geacintov, Nicholas E., Grollman, Arthur P.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.56 MB

english, 1993

50

Effective Utilization of N 2 -Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases †

Matsuda, Tomonari, Terashima, Isamu, Matsumoto, Yoshihiro, Yabushita, Hisatoshi, Matsui, Saburo, Shibutani, Shinya

Journal:

Year:

1999

Language:

english

File:

PDF, 181 KB

english, 1999