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1

Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels

Hoffman, Alexander, Taleski, Goce, Qian, Helena, Wasek, Brandi, Arning, Erland, Bottiglieri, Teodoro, Sontag, Jean-Marie, Sontag, Estelle, Götz, Jürgen

Journal:

Journal of Alzheimer's Disease

Year:

2018

Language:

english

File:

PDF, 725 KB

english, 2018

2

Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells

Jean-Marie Sontag, Viyada Nunbhakdi-Craig, Martina Mitterhuber, Egon Ogris, Estelle Sontag

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 792 KB

english, 2010

3

The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: A triple threat in the regulation of the neuronal cytoskeleton

Hoffman, Alexander, Taleski, Goce, Sontag, Estelle

Journal:

Molecular and Cellular Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.65 MB

english, 2017

4

Protein phosphatase 2A: a definite player in viral and parasitic regulation

Alphonse Garcia, Xavier Cayla, Estelle Sontag

Journal:

Microbes and Infection

Year:

2000

Language:

english

File:

PDF, 443 KB

english, 2000

5

Reduced Binding of Protein Phosphatase 2A to Tau Protein with Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Mutations

Michel Goedert, Sivapong Satumtira, Ross Jakes, Michael J. Smith, Craig Kamibayashi, Charles L. White III, Estelle Sontag

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 221 KB

english, 2000

6

Expression of protein phosphatase 2A mutants and silencing of the regulatory Bα subunit induce a selective loss of acetylated and detyrosinated microtubules

Viyada Nunbhakdi-Craig, Stefan Schuechner, Jean-Marie Sontag, Lisa Montgomery, David C. Pallas, Claudia Juno, Ingrid Mudrak, Egon Ogris, Estelle Sontag

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 1.01 MB

english, 2007

7

Protein phosphatase 2A: the Trojan Horse of cellular signaling

Journal:

Cellular Signalling

Year:

2001

Language:

english

File:

PDF, 341 KB

english, 2001

8

Regulation of the Phosphorylation State and Microtubule-Binding Activity of Tau by Protein Phosphatase 2A

Estelle Sontag, Viyada Nunbhakdi-Craig, Gloria Lee, George S. Bloom, Marc C. Mumby

Journal:

Year:

1996

Language:

english

File:

PDF, 4.26 MB

english, 1996

9

Role of PP2A methylation pathways in tau regulation

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 37 KB

english, 2009

10

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation

Estelle Sontag, Sergei Fedorov, Craig Kamibayashi, David Robbins, Melanie Cobb, Marc Mumby

Journal:

Year:

1993

Language:

english

File:

PDF, 1.77 MB

english, 1993

11

A Novel Pool of Protein Phosphatase 2A Is Associated with Microtubules and Is Regulated during the Cell Cycle

Estelle Sontag, Viyada Nunbhakdi-Craig, George S. Bloom and Marc C. Mumby

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 4.83 MB

english, 1995

12

Structural and Functional Implications of Tau Hyperphosphorylation: Information from Phosphorylation-Mimicking Mutated Tau Proteins †

Eidenmüller, Jochen, Fath, Thomas, Hellwig, Andrea, Reed, Jennifer, Sontag, Estelle, Brandt, Roland

Journal:

Year:

2000

Language:

english

File:

PDF, 287 KB

english, 2000

13

Leucine Carboxyl Methyltransferase 1 (LCMT1)-dependent Methylation Regulates the Association of Protein Phosphatase 2A and Tau Protein with Plasma Membrane Microdomains in Neuroblastoma Cells

Sontag, Jean-Marie, Nunbhakdi-Craig, Viyada, Sontag, Estelle

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 2.24 MB

english, 2013

14

Protein phosphatase 2A dysfunction in Alzheimerâ€™s disease

Sontag, Jean-Marie, Sontag, Estelle

Journal:

Frontiers in Molecular Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

15

FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation

Ahmed, Abdulrzag F., de Bock, Charles E., Lincz, Lisa F., Pundavela, Jay, Zouikr, Ihssane, Sontag, Estelle, Hondermarck, Hubert, Thorne, Rick F.

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 2.31 MB

english, 2015

16

Protein Phosphatase 2A Associates with and Regulates Atypical PKC and the Epithelial Tight Junction Complex

Viyada Nunbhakdi-Craig, Thomas Machleidt, Egon Ogris, Dennis Bellotto, Charles L. White, III and Estelle Sontag

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 3.12 MB

english, 2002

17

Downregulation of Protein Phosphatase 2A Carboxyl Methylation and Methyltransferase May Contribute to Alzheimer Disease Pathogenesis

Sontag, Estelle, Hladik, Christa, Montgomery, Lisa, Luangpirom, Ampa, Mudrak, Ingrid, Ogris, Egon, White, Charles L.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 996 KB

english, 2004

18

Cortical Synapse Loss in progressive Supranuclear palsy

Bigio, Eileen H., Vono, Mary Beth, Satumtira, Sivapong, Adamson, Jennifer, Sontag, Estelle, Hynan, Linda S., White, Charles L., Baker, Matt, Hutton, Mike

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

19

Altered Expression Levels of the Protein Phosphatase 2A ABαC Enzyme Are Associated with Alzheimer Disease Pathology

Sontag, Estelle, Luangpirom, Ampa, Hladik, Christa, Mudrak, Ingrid, Ogris, Egon, Speciale, Samuel, White, Charles L.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 1.68 MB

english, 2004

20

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

EIDENMÜLLER, Jochen, FATH, Thomas, MAAS, Thorsten, POOL, Madeline, SONTAG, Estelle, BRANDT, Roland

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 293 KB

english, 2001

21

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

EIDENMÜLLER, Jochen, FATH, Thomas, MAAS, Thorsten, POOL, Madeline, SONTAG, Estelle, BRANDT, Roland

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 293 KB

english, 2001

22

Contribution of Asymmetric Synapse Loss to Lateralizing Clinical Deficits in Frontotemporal Dementias

Lipton, Anne M., Cullum, C. Munro, Satumtira, Sivapong, Sontag, Estelle, Hynan, Linda S., White III, Charles L., Bigio, Eileen H.

Journal:

Archives of Neurology

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

23

Protein phosphatase 2A and Tau: An orchestrated “Pas de Deux”

Taleski, Goce, Sontag, Estelle

Journal:

Year:

2017

Language:

english

File:

PDF, 981 KB

english, 2017

24

Specificity of research antibodies: “trust is good, validation is better”

Ogris, Egon, Sontag, Estelle, Wadzinski, Brian, Narla, Goutham

Journal:

Human Pathology

Year:

2017

Language:

english

File:

PDF, 366 KB

english, 2017

25

Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice

Sontag, Jean-Marie, Wasek, Brandi, Taleski, Goce, Smith, Josephine, Arning, Erland, Sontag, Estelle, Bottiglieri, Teodoro

Journal:

Frontiers in Aging Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014

26

FAT1 cadherin controls neuritogenesis during NTera2 cell differentiation

Ahmed, Abdulrzag F., de Bock, Charles E., Sontag, Estelle, Hondermarck, Hubert, Lincz, Lisa F., Thorne, Rick F.

Journal:

Biochemical and Biophysical Research Communications

Year:

2019

Language:

english

File:

PDF, 1.37 MB

english, 2019

27

PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation

Frohner, Ingrid E., Mudrak, Ingrid, SchÃ¼chner, Stefan, Anrather, Dorothea, Hartl, Markus, Sontag, Jean-Marie, Sontag, Estelle, Wadzinski, Brian E., Preglej, Teresa, Ellmeier, Wilfried, Ogris, Egon

Journal:

Year:

2020

File:

PDF, 2.32 MB

2020