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51

Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression

Puzanov, Igor, Amaravadi, Ravi K., McArthur, Grant A., Flaherty, Keith T., Chapman, Paul B., Sosman, Jeffrey A., Ribas, Antoni, Shackleton, Mark, Hwu, Patrick, Chmielowski, Bartosz, Nolop, Keith B., L

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

52

Spindle Cell Squamous Carcinoma During BRAF Inhibitor Therapy for Advanced Melanoma

Cohen, Daniel N., Lumbang, Wilfred A., Boyd, Alan S., Sosman, Jeffrey A., Zwerner, Jeffrey P.

Journal:

JAMA Dermatology

Year:

2014

Language:

english

File:

PDF, 420 KB

english, 2014

53

A Phase II Study of Bevacizumab and High-dose Interleukin-2 in Patients With Metastatic Renal Cell Carcinoma

Dandamudi, Uday B., Ghebremichael, Musie, Sosman, Jeffrey A., Clark, Joseph I., McDermott, David F., Atkins, Michael B., Dutcher, Janice P., Urba, Walter J., Regan, Meredith M., Puzanov, Igor, Crocenz

Journal:

Journal of Immunotherapy

Year:

2013

Language:

english

File:

PDF, 159 KB

english, 2013

54

Therapeutic Advances and Treatment Options in Metastatic Melanoma

Johnson, Douglas B., Sosman, Jeffrey A.

Journal:

Year:

2015

Language:

english

File:

PDF, 156 KB

english, 2015

55

The MEK inhibitor trametinib for the treatment of advanced melanoma

Johnson, Douglas B, Hames, Megan L, Sosman, Jeffrey A

Journal:

Expert Opinion on Orphan Drugs

Year:

2014

Language:

english

File:

PDF, 297 KB

english, 2014

56

Melanoma and a Headache

Johnson, Douglas B., Mudigonda, Tejaswi V., Sosman, Jeffrey A.

Journal:

Year:

2015

Language:

english

File:

PDF, 150 KB

english, 2015

57

Molecular Targeted Therapy Approaches for BRAF Wild-Type Melanoma

Johnpulle, Romany A. N., Johnson, Douglas B., Sosman, Jeffrey A.

Journal:

Current Oncology Reports

Year:

2016

Language:

english

File:

PDF, 498 KB

english, 2016

58

Melanoma driver mutations and immune therapy

Johnson, Douglas B., Lovly, Christine M., Sullivan, Ryan J., Carvajal, Richard D., Sosman, Jeffrey A.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.39 MB

english, 2016

59

Impact of Medical and Nonmedical Factors on Physician Decision Making for HIV/AIDS Antiretroviral Treatment

Bogart, Laura M., Kelly, Jeffrey A., Catz, Sheryl L., Sosman, James M.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2000

File:

PDF, 3.57 MB

2000

60

CUSTOM-SEQ: A Prototype for Oncology Rapid Learning in a Comprehensive EHR Environment

Warner, Jeremy L., Wang, Lucy, Pao, William, Sosman, Jeffrey A., Atreya, Ravi V., Carney, Pam, Levy, Mia A.

Journal:

Journal of the American Medical Informatics Association

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

61

Emerging Targeted Therapies for Melanoma

Johnson, Douglas B., Pollack, Megan H., Sosman, Jeffrey A.

Journal:

Expert Opinion on Emerging Drugs

Year:

2016

Language:

english

File:

PDF, 692 KB

english, 2016

62

Sequential administration of nivolumab and ipilimumab with a planned switch in patients with advanced melanoma (CheckMate 064): an open-label, randomised, phase 2 trial

Weber, Jeffrey S, Gibney, Geoff, Sullivan, Ryan J, Sosman, Jeffrey A, Slingluff, Craig L, Lawrence, Donald P, Logan, Theodore F, Schuchter, Lynn M, Nair, Suresh, Fecher, Leslie, Buchbinder, Elizabeth

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 598 KB

english, 2016

63

Dacarbazine induced acute myeloid leukemia in melanoma

Collins, Carletta M., Morgan, David S., Mosse, Claudio, Sosman, Jeffrey

Journal:

Melanoma Research

Year:

2009

Language:

english

File:

PDF, 188 KB

english, 2009

64

Phase 2 study of sunitinib in patients with metastatic mucosal or acral melanoma

Buchbinder, Elizabeth I., Sosman, Jeffrey A., Lawrence, Donald P., McDermott, David F., Ramaiya, Nikhil H., Van den Abbeele, Annick D., Linette, Gerald P., Giobbie-Hurder, Anita, Hodi, F. Stephen

Journal:

Year:

2015

Language:

english

File:

PDF, 283 KB

english, 2015

65

Retrospective Analysis of the Safety and Efficacy of Interleukin-2 After Prior VEGF-targeted Therapy in Patients With Advanced Renal Cell Carcinoma

Cho, Daniel C., Puzanov, Igor, Regan, Meredith M., Schwarzberg, Talya, Seery, Virginia, Lee, Mee-Young, Liu, Vivian, Bhatt, Rupal, Koon, Henry, Mier, James W., Sosman, Jeffrey A., Atkins, Michael B.,

Journal:

Journal of Immunotherapy

Year:

2009

Language:

english

File:

PDF, 103 KB

english, 2009

66

Phase I/II Trial of Outpatient PEG-interferon With Interleukin-2 in Advanced Renal Cell Carcinoma: A Cytokine Working Group Study

Clark, Joseph I., Mehrabi, Jessica, Sosman, Jeffrey A., Logan, Theodore F., Margolin, Kim A., Dutcher, Janice P., Urba, Walter J., Ernstoff, Marc S., McDermott, David F., Lau, Ann M., Atkins, Michael

Journal:

Journal of Immunotherapy

Year:

2007

Language:

english

File:

PDF, 146 KB

english, 2007

67

A Phase II Study of the Continuous Intravenous Infusion of Interleukin-6 for Metastatic Renal Cell Carcinoma

Weiss, Geoffrey R., Margolin, Kim A., Sznol, Mario, Atkins, Michael B., Oleksowicz, Leslie, Isaacs, Randi, Sosman, Jeffrey A., Doroshow, James H., Treh, Elizabeth G., Dutcher, Janice P., Fisher, Richa

Journal:

Journal of Immunotherapy

Year:

1995

File:

PDF, 462 KB

1995

68

A Phase IA/IB Trial of Anti-CD3 Murine Monoclonal Antibody plus Low-Dose Continuous-Infusion Interleukin-2 in Advanced Cancer Patients

Sosman, Jeffrey A., Kefer, Catherine, Fisher, Richard I., Jacobs, Cheryl D., Pumfery, Peggy, Ellis, Thomas M.

Journal:

Journal of Immunotherapy

Year:

1995

File:

PDF, 863 KB

1995

69

How I Treat Patients with BRAF Wild-Type Metastatic Melanoma

Sosman, Jeffrey A., Johnson, Douglas B.

Journal:

Year:

2013

Language:

english

File:

PDF, 494 KB

english, 2013

70

Activation of Human T Cells Obtained Pre- and Post-Interleukin-2 (IL-2) Therapy by Anti-CD3 Monoclonal Antibody plus IL-2

Weil-Hillman, Gilda, Schell, Kathleen, Segal, David M., Hank, Jacquelyn A., Sosman, Jeffrey A., Sondel, Paul M.

Journal:

Journal of Immunotherapy

Year:

1991

File:

PDF, 934 KB

1991

71

SPECIFIC RECOGNITION OF HUMAN LEUKEMIC CELLS BY ALLOGENEIC T CELL LINES

SOSMAN, JEFFREY A., OETTEL, KURT R., HANK, JACQUELYN A., FISCH, PAUL, SONDEL, PAUL M.

Journal:

Transplantation Journal

Year:

1989

File:

PDF, 1.00 MB

1989

72

The Graft-vs.-Leukemia Effect

Sosman, Jeffrey A., Sondel, Paul M.

Journal:

Journal of Pediatric Hematology/Oncology

Year:

1993

File:

PDF, 983 KB

1993

73

Comparative analysis of the GNAQ , GNA11 , SF3B1 , and EIF1AX driver mutations in melanoma and across the cancer spectrum

Johnson, Douglas B., Roszik, Jason, Shoushtari, Alexander N., Eroglu, Zeynep, Balko, Justin M., Higham, Catherine, Puzanov, Igor, Patel, Sapna P., Sosman, Jeffrey A., Woodman, Scott E.

Journal:

Pigment Cell & Melanoma Research

Year:

2016

Language:

english

File:

PDF, 450 KB

english, 2016

74

PD-1/PD-L1 blockade in renal cell cancer

Beckermann, Kathryn E., Johnson, Douglas B., Sosman, Jeffrey A.

Journal:

Expert Review of Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 859 KB

english, 2016

75

A phase II trial of erlotinib and bevacizumab for patients with metastatic melanoma

Mudigonda, Tejaswi V., Wyman, Kenneth, Spigel, David R., Dahlman, Kimberly B., Greco, F. Anthony, Puzanov, Igor, Kelley, Mark C., Hainsworth, John D., Sosman, Jeffrey A., Johnson, Douglas B.

Journal:

Pigment Cell & Melanoma Research

Year:

2016

Language:

english

File:

PDF, 354 KB

english, 2016

76

Clinical outcomes in metastatic uveal melanoma treated with PD-1 and PD-L1 antibodies

Algazi, Alain P., Tsai, Katy K., Shoushtari, Alexander N., Munhoz, Rodrigo R., Eroglu, Zeynep, Piulats, Josep M., Ott, Patrick A., Johnson, Douglas B., Hwang, Jimmy, Daud, Adil I., Sosman, Jeffrey A.,

Journal:

Year:

2016

Language:

english

File:

PDF, 251 KB

english, 2016

77

A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors

Adjei, Alex A., LoRusso, Patricia, Ribas, Antoni, Sosman, Jeffrey A., Pavlick, Anna, Dy, Grace K., Zhou, Xiaofei, Gangolli, Esha, Kneissl, Michelle, Faucette, Stephanie, Neuwirth, Rachel, Bózon, Vivia

Journal:

Investigational New Drugs

Year:

2017

Language:

english

File:

PDF, 772 KB

english, 2017

78

Safety and efficacy of anti-PD-1 in patients with baseline cardiac, renal, or hepatic dysfunction

Kanz, Bridgette A., Pollack, Megan H., Johnpulle, Romany, Puzanov, Igor, Horn, Leora, Morgans, Alicia, Sosman, Jeffrey A., Rapisuwon, Suthee, Conry, R. Martin, Eroglu, Zeynep, Johnson, Douglas B.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2016

Language:

english

File:

PDF, 700 KB

english, 2016

79

Responses to immune checkpoint inhibitors in nonagenarians

Johnpulle, Romany A. N., Conry, Robert M., Sosman, Jeffrey A., Puzanov, Igor, Johnson, Douglas B.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

80

Advancements in unresectable melanoma: a multidisciplinary perspective

Malecek, Mary-Kate, Robinson, June K, Bilimoria, Karl, Choi, Jennifer N, Choi, Jaehyuk, Gerami, Pedram, Kruser, Timothy, Kuzel, Timothy, Martini, Mary, Strauss, Jonathan B, Wayne, Jeffrey, Sosman, Jef

Journal:

Melanoma Management

Year:

2016

Language:

english

File:

PDF, 1.69 MB

english, 2016

81

Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis

D’Angelo, Sandra P., Larkin, James, Sosman, Jeffrey A., Lebbé, Celeste, Brady, Benjamin, Neyns, Bart, Schmidt, Henrik, Hassel, Jessica C., Hodi, F. Stephen, Lorigan, Paul, Savage, Kerry J., Miller, Wi

Journal:

Journal of Clinical Oncology

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

82

Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma

Atkinson, Thomas M., Hay, Jennifer L., Shoushtari, Alexander, Li, Yuelin, Paucar, Daniel J., Smith, Sloane C., Kudchadkar, Ragini R., Doyle, Austin, Sosman, Jeffrey A., Quevedo, Jorge Fernando, Milhem

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2017

Language:

english

File:

PDF, 436 KB

english, 2017

83

MYOCARDITIS AND RHABDOMYOLYSIS INCIDENCE WITH IMMUNE CHECKPOINT INHIBITORS

Bloomer, Tyler, Alexander, Matthew, Lenihan, Daniel, Slosky, David, Becker, Jason, Sosman, Jeffrey, Johnson, Douglas, Moslehi, Javid

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 338 KB

english, 2017

84

Clinical Features of Acquired Resistance to Anti–PD-1 Therapy in Advanced Melanoma

Wang, Daniel Y., Eroglu, Zeynep, Ozgun, Alpaslan, Leger, Paul D., Zhao, Shilin, Ye, Fei, Luke, Jason J., Joseph, Richard W., Haq, Rizwan, Ott, Patrick A., Hodi, F. Stephen, Sosman, Jeffrey A., Johnson

Journal:

Cancer Immunology Research

Year:

2017

File:

PDF, 398 KB

2017

85

Treatment Beyond Progression in Patients with Advanced Renal Cell Carcinoma Treated with Nivolumab in CheckMate 025

Escudier, Bernard, Motzer, Robert J., Sharma, Padmanee, Wagstaff, John, Plimack, Elizabeth R., Hammers, Hans J., Donskov, Frede, Gurney, Howard, Sosman, Jeffrey A., Zalewski, Pawel G., Harmenberg, Ulr

Journal:

European Urology

Year:

2017

Language:

english

File:

PDF, 413 KB

english, 2017

86

Gene Expression Profiling in BRAF -Mutated Melanoma Reveals Patient Subgroups With Poor Outcomes to Vemurafenib That May Be Overcome by Cobimetinib Plus Vemurafenib

Wongchenko, Matthew J, McArthur, Grant A., Dréno, Brigitte, Larkin, James, Ascierto, Paolo A, Sosman, Jeffrey, Andries, Luc, Kockx, Mark, Hurst, Stephen D, Caro, Ivor, Rooney, Isabelle, Hegde, Priti S

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 12.24 MB

english, 2017

87

Emerging Growth Factor Receptor Antagonists for the Treatment of Advanced Melanoma

Fenton, Sarah E., Sosman, Jeffrey A., Chandra, Sunandana

Journal:

Expert Opinion on Emerging Drugs

Year:

2017

Language:

english

File:

PDF, 803 KB

english, 2017

88

Sequencing Treatment in BRAFV600 Mutant Melanoma

Johnson, Douglas B., Pectasides, Eirini, Feld, Emily, Ye, Fei, Zhao, Shilin, Johnpulle, Romany, Merritt, Ryan, McDermott, David F., Puzanov, Igor, Lawrence, Donald, Sosman, Jeffrey A., Buchbinder, Eli

Journal:

Journal of Immunotherapy

Year:

2017

Language:

english

File:

PDF, 220 KB

english, 2017

89

Cancer Immunotherapies: Are They as Effective in the Elderly?

Poropatich, Kate, Fontanarosa, Joel, Samant, Sandeep, Sosman, Jeffrey A., Zhang, Bin

Journal:

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

90

Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival

Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen L., Wu, Meijing, Genet, Matthew, Gritsina, Galina, Győrffy, Balázs, Brastianos, Priscilla K, Binder, David, Sosman, Jeffrey A, Giles, Francis J., James,

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 15.21 MB

english, 2017

91

Novel Targeted Therapies for Metastatic Melanoma

Iams, Wade T., Sosman, Jeffrey A., Chandra, Sunandana

Journal:

The Cancer Journal

Year:

2017

Language:

english

File:

PDF, 133 KB

english, 2017

92

First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study

Sullivan, Ryan J., Infante, Jeffrey R., Janku, Filip, Wong, Deborah Jean Lee, Sosman, Jeffrey A., Keedy, Vicki, Patel, Manish R., Shapiro, Geoffrey I., Mier, James W., Tolcher, Anthony W., Wang-Gillam

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 3.32 MB

english, 2017

93

BRAF V600E -Mutant Melanoma Presenting With Cardiac Involvement

Johnson, Douglas B., Sosman, Jeffrey A.

Journal:

Journal of the National Comprehensive Cancer Network

Year:

2014

Language:

english

File:

PDF, 195 KB

english, 2014

94

Erratum to “CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma” [Eur Urol 2017;72:962–71]

Escudier, Bernard, Sharma, Padmanee, McDermott, David F., George, Saby, Hammers, Hans J., Srinivas, Sandhya, Tykodi, Scott S., Sosman, Jeffrey A., Procopio, Giuseppe, Plimack, Elizabeth R., Castellano

Journal:

European Urology

Year:

2018

Language:

english

File:

PDF, 719 KB

english, 2018

95

Increased reporting of fatal immune checkpoint inhibitor-associated myocarditis

Moslehi, Javid J, Salem, Joe-Elie, Sosman, Jeffrey A, Lebrun-Vignes, Bénédicte, Johnson, Douglas B

Journal:

Lancet (London, England)

Year:

2018

Language:

english

File:

PDF, 170 KB

english, 2018

96

Melanoma: What do all the mutations mean?

Davis, Elizabeth J., Johnson, Douglas B., Sosman, Jeffrey A., Chandra, Sunandana

Journal:

Year:

2018

Language:

english

File:

PDF, 377 KB

english, 2018

97

Combining Tumor Vaccination and Oncolytic Viral Approaches with Checkpoint Inhibitors: Rationale, Pre-Clinical Experience, and Current Clinical Trials in Malignant Melanoma

Cavalcante, Ludimila, Chowdhary, Akansha, Sosman, Jeffrey A., Chandra, Sunandana

Journal:

American Journal of Clinical Dermatology

Year:

2018

Language:

english

File:

PDF, 499 KB

english, 2018

98

Reporting of immune checkpoint inhibitor-associated myocarditis – Authors' reply

Moslehi, Javid J, Salem, Joe-Elie, Sosman, Jeffrey A, Lebrun-Vignes, Bénédicte, Johnson, Douglas B

Journal:

Lancet (London, England)

Year:

2018

Language:

english

File:

PDF, 138 KB

english, 2018

99

Toxicity profile of approved anti-PD-1 monoclonal antibodies in solid tumors: a systematic review and meta-analysis of randomized clinical trials

Costa, Ricardo, Carneiro, Benedito A., Agulnik, Mark, Rademaker, Alfred W., Pai, Sachin G., Villaflor, Victoria M., Cristofanilli, Massimo, Sosman, Jeffrey A., Giles, Francis J.

Journal:

Year:

2017

Language:

english

File:

PDF, 776 KB

english, 2017

100

Immune Checkpoint Inhibitor Toxicity in 2018

Johnson, Douglas B., Chandra, Sunandana, Sosman, Jeffrey A.

Journal:

Year:

2018

Language:

english

File:

PDF, 99 KB

english, 2018