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51

PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

Phillip T. Hawkins, Alicia Eguinoa, Rong-Guo Qiu, David Stokoe, Frank T. Cooke, Rhodri Walters, Stefan Wennström, Lena Claesson-Welsh, Tony Evans, Marc Symons, Len Stephens

Journal:

Current Biology

Year:

1995

Language:

english

File:

PDF, 3.37 MB

english, 1995

52

Estimating minke whale (Balaenoptera acutorostrata) boing sound density using passive acoustic sensors

Stephen W. Martin, Tiago A. Marques, Len Thomas, Ronald P. Morrissey, Susan Jarvis, Nancy DiMarzio, David Moretti, David K. Mellinger

Journal:

Marine Mammal Science

Year:

2012

Language:

english

File:

PDF, 700 KB

english, 2012

53

Estimating abundance of cryptic but trappable animals using trapping point transects: a case study for Key Largo woodrats

Joanne M. Potts, Stephen T. Buckland, Len Thomas, Anne Savage

Journal:

Methods in Ecology and Evolution

Year:

2012

Language:

english

File:

PDF, 881 KB

english, 2012

54

Field Trials of Line Transect Methods Applied to Estimation of Desert Tortoise Abundance

David R. Anderson, Kenneth P. Burnham, Bruce C. Lubow, Len Thomas, Paul Stephen Corn, Philip A. Medica and Ronald W. Marlow

Journal:

Journal of Wildlife Management

Year:

2001

Language:

english

File:

PDF, 2.56 MB

english, 2001

55

GPCR activation of Ras and PI3Kγ in neutrophils depends on PLCβ2/β3 and the RasGEF RasGRP4

Suire, Sabine, Lécureuil, Charlotte, Anderson, Karen E, Damoulakis, George, Niewczas, Izabella, Davidson, Keith, Guillou, Hervé, Pan, Dingxin, Clark, Jonathan, Hawkins, Phillip T, Stephens, Len

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 968 KB

english, 2012

56

The efficacy of the addition of nifedipine in patients with mixed angina compared to patients with classic exertional angina: A multicenter, randomized, double-blind, placebo-controlled clinical trial

Peter H Stone, James H Ware, Marcus A DeWood, Joel M Gore, Robert H Eich, Daniel A Pietro, Alfred F Parisi, Richard W Nesto, William E Boden, Satish C Sharma, Stephen C Vlay, Len E Ennis, Ralph E Gian

Journal:

American Heart Journal

Year:

1988

Language:

english

File:

PDF, 1.28 MB

english, 1988

57

Insulin and ATP stimulate actin polymerization in U937 cells by a wortmannin-sensitive mechanism

Rhodri J. Walters, Phill Hawkins, Frank T. Cooke, Alicia Eguinoa, Len R. Stephens

Journal:

Year:

1996

Language:

english

File:

PDF, 360 KB

english, 1996

58

Phosphoinositide 3-kinases as drug targets in cancer

Len Stephens, Roger Williams, Phillip Hawkins

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 522 KB

english, 2005

59

Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio

Stephen M Altmann, Mark T Mellon, Marc C Johnson, Barry H Paw, Nikolaus S Trede, Len I Zon, Carol H Kim

Journal:

Developmental & Comparative Immunology

Year:

2004

Language:

english

File:

PDF, 668 KB

english, 2004

60

P-Rex2, a new guanine-nucleotide exchange factor for Rac

Sarah Donald, Kirsti Hill, Charlotte Lecureuil, Romain Barnouin, Sonja Krugmann, W. John Coadwell, Simon R. Andrews, Simon A. Walker, Phillip T. Hawkins, Len R. Stephens, Heidi C.E. Welch

Journal:

Year:

2004

Language:

english

File:

PDF, 211 KB

english, 2004

61

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

Xuxiao Zhang, Oscar Vadas, Olga Perisic, Karen E. Anderson, Jonathan Clark, Phillip T. Hawkins, Len R. Stephens, Roger L. Williams

Journal:

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011

62

Phosphoinositide 3-kinase-dependent activation of Rac

Heidi C.E. Welch, W.John Coadwell, Len R. Stephens, Phillip T. Hawkins

Journal:

Year:

2003

Language:

english

File:

PDF, 220 KB

english, 2003

63

Priming of human neutrophil superoxide generation by tumour necrosis factor-α is signalled by enhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol 1,4,5-trisphosphate accumulation

Alison M Condliffe, Phillip T Hawkins, Len R Stephens, Christopher Haslett, Edwin R Chilvers

Journal:

Year:

1998

Language:

english

File:

PDF, 155 KB

english, 1998

64

Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ

Michael E. Pacold, Sabine Suire, Olga Perisic, Samuel Lara-Gonzalez, Colin T. Davis, Edward H. Walker, Phillip T. Hawkins, Len Stephens, John F. Eccleston, Roger L. Williams

Journal:

Year:

2000

Language:

english

File:

PDF, 1.79 MB

english, 2000

65

P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac

Heidi C.E. Welch, W.John Coadwell, Christian D. Ellson, G.John Ferguson, Simon R. Andrews, Hediye Erdjument-Bromage, Paul Tempst, Phillip T. Hawkins, Len R. Stephens

Journal:

Year:

2002

Language:

english

File:

PDF, 812 KB

english, 2002

66

The Crystal Structure of the PX Domain from p40phox Bound to Phosphatidylinositol 3-Phosphate

Jerónimo Bravo, Dimitrios Karathanassis, Christine M Pacold, Michael E Pacold, Chris D Ellson, Karen E Anderson, P.Jonathan G Butler, Isabelle Lavenir, Olga Perisic, Phillip T Hawkins, Len Stephens, R

Journal:

Year:

2001

Language:

english

File:

PDF, 731 KB

english, 2001

67

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

Edward H. Walker, Michael E. Pacold, Olga Perisic, Len Stephens, Philip T. Hawkins, Matthias P. Wymann, Roger L. Williams

Journal:

Year:

2000

Language:

english

File:

PDF, 1.52 MB

english, 2000

68

Genome resequencing reveals multiscale geographic structure and extensive linkage disequilibrium in the forest tree Populus trichocarpa

Gancho T. Slavov, Stephen P. DiFazio, Joel Martin, Wendy Schackwitz, Wellington Muchero, Eli Rodgers-Melnick, Mindie F. Lipphardt, Christa P. Pennacchio, Uffe Hellsten, Len A. Pennacchio, Lee E. Gunte

Journal:

New Phytologist

Year:

2012

Language:

english

File:

PDF, 1018 KB

english, 2012

69

“Wet Diapers - Dry Patients”: An effective dressing for patients undergoing arthroscopic shoulder surgery

Atul Kapila, Amit Bhargava, Len Funk, Stephen Copeland, Ofer Levy

Journal:

Arthroscopy: The Journal of Arthroscopic & Related Surgery

Year:

2005

Language:

english

File:

PDF, 136 KB

english, 2005

70

Hepatitis G virus and fulminant hepatic failure: evidence for transfusion-related infection

Len D. Moaven, Stephen A. Locarnini, D.Scott Bowden, Jungsuh P. Kim, Alan Breschkin, Rhonda McCaw, Andersen Yun, John Wages Jr, Bob Jones, Peter Angus

Journal:

Journal of Hepatology

Year:

1997

Language:

english

File:

PDF, 501 KB

english, 1997

71

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

Karen E. Anderson, John Coadwell, Len R. Stephens, Phillip T. Hawkins

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 306 KB

english, 1998

72

Signalling via class IA PI3Ks

Len Stephens, Phill Hawkins

Journal:

Advances in Enzyme Regulation

Year:

2011

Language:

english

File:

PDF, 148 KB

english, 2011

73

Periovulatory human oocytes, cumulus cells, and ovarian leukocytes express type 1 but not type 2 11β-hydroxysteroid dehydrogenase RNA

Michael P Smith, Raj S Mathur, Stephen D Keay, Len Hall, Michael G.R Hull, Julian M Jenkins

Journal:

Fertility and Sterility

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

74

Activation of the neutrophil NADPH oxidase by Aspergillus fumigatus

Boyle, Keith B., Stephens, Len R., Hawkins, Phillip T.

Journal:

Annals of the New York Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 561 KB

english, 2012

75

The importance of prior choice in model selection: a density dependence example

Lawrence, James D., Gramacy, Robert B., Thomas, Len, Buckland, Stephen T., Freckleton, Robert

Journal:

Methods in Ecology and Evolution

Year:

2013

Language:

english

File:

PDF, 777 KB

english, 2013

76

IMPROVING ESTIMATES OF BIRD DENSITY USING MULTIPLE- COVARIATE DISTANCE SAMPLING

Marques, Tiago A., Thomas, Len, Fancy, Steven G., Buckland, Stephen T.

Journal:

Year:

2007

File:

PDF, 943 KB

2007

77

Estimating animal population density using passive acoustics

Marques, Tiago A., Thomas, Len, Martin, Stephen W., Mellinger, David K., Ward, Jessica A., Moretti, David J., Harris, Danielle, Tyack, Peter L.

Journal:

Biological Reviews

Year:

2013

Language:

english

File:

PDF, 872 KB

english, 2013

78

Orally Active Oxime Derivatives of the Dopaminergic Prodrug 6-( N , N -Di- n -propylamino)-3,4,5,6,7,8-hexahydro-2 H -naphthalen-1-one. Synthesis and Pharmacological Activity

Venhuis, Bastiaan J., Dijkstra, Durk, Wustrow, David, Meltzer, Len T., Wise, Lawrence D., Johnson, Stephen J., Wikström, Håkan V.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 67 KB

english, 2003

79

3D time series analysis of cell shape using Laplacian approaches

Du, Cheng-Jin, Hawkins, Phillip T, Stephens, Len R, Bretschneider, Till

Journal:

BMC Bioinformatics

Year:

2013

Language:

english

File:

PDF, 926 KB

english, 2013

80

BMX Acts Downstream of PI3K to Promote Colorectal Cancer Cell Survival and Pathway Inhibition Sensitizes to the BH3 Mimetic ABT-737

Potter, Danielle S., Kelly, Paul, Denneny, Olive, Juvin, Veronique, Stephens, Len R., Dive, Caroline, Morrow, Christopher J.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

81

c-Myc-Induced Extrachromosomal Elements Carry Active Chromatin

Smith, Greg, Taylor-Kashton, Cheryl, Dushnicky, Len, Symons, Stephen, Wright, Jim, Mai, Sabine

Journal:

Year:

2003

Language:

english

File:

PDF, 544 KB

english, 2003

82

A new approach to measuring phosphoinositides in cells by mass spectrometry

Kielkowska, Anna, Niewczas, Izabella, Anderson, Karen E., Durrant, Tom N., Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.

Journal:

Advances in Biological Regulation

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

83

Evidence that DNA Damage Triggers Interleukin 10 Cytokine Production in UV-Irradiated Murine Keratinocytes

Chikako Nishigori, Daniel B. Yarosh, Stephen E. Ullrich, Arie A. Vink, Corazon D. Bucana, Len Roza and Margaret L. Kripke

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.68 MB

english, 1996

84

The inhibition of Antigen-Presenting Activity of Dendritic Cells Resulting from UV Irradiation of Murine Skin is Restored by in vitro Photorepair of Cyclobutane Pyrimidine Dimers

Arie A. Vink, Angus M. Moodycliffe, Vijay Shreedhar, Stephen E. Ullrich, Len Roza, Danile B. Yarosh and Margaret L. Kripke

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.21 MB

english, 1997

85

Current Understanding of Intracellular Signalling Pathways || A Heterotrimeric GTPase-Regulated Isoform of PI3K and the Regulation of its Potential Effectors [and Discussion]

Len Stephens, P. T. Hawkins, A. Eguinoa, F. Cooke, J. Saklatvala, E. Rozengurt and M. Karin

Journal:

Philosophical Transactions Biological Sciences

Year:

1996

Language:

english

File:

PDF, 715 KB

english, 1996

86

Embedding Population Dynamics Models in Inference

Buckland, Stephen T., Newman, Ken B., Fernández, Carmen, Thomas, Len, Harwood, John

Journal:

Statistical Science

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

87

Brentuximab Vedotin Is Associated with Improved Progression-Free Survival after Allogeneic Transplantation for Hodgkin Lymphoma

Chen, Robert, Palmer, Joycelynne M., Tsai, Ni-Chun, Thomas, Sandra H., Siddiqi, Tanya, Popplewell, Leslie, Farol, Len, Nademanee, Auayporn, Forman, Stephen J.

Journal:

Biology of Blood and Marrow Transplantation

Year:

2014

Language:

english

File:

PDF, 128 KB

english, 2014

88

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation

Jones, David R., Keune, Willem-Jan, Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Divecha, Nullin

Journal:

Year:

2014

Language:

english

File:

PDF, 748 KB

english, 2014

89

[IEEE 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012) - Barcelona, Spain (2012.05.2-2012.05.5)] 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI) - Fast random walker for neutrophil cell segmentation in 3D

Du, Cheng-Jin, Ferguson, John G., Hawkins, Phillip T., Stephens, Len R., Bretschneider, Till

Year:

2012

Language:

english

File:

PDF, 953 KB

english, 2012

90

A double-blind controlled study of methylphenidate treatment in closed head injury

Speech, Thomas J., Rao, Stephen M., Osmon, David C., Sperry, Len T.

Journal:

Year:

1993

Language:

english

File:

PDF, 392 KB

english, 1993

91

An interview with Geoff Whitty & Michael Worton

Barton, Len, Rowland, Stephen

Journal:

Teaching in Higher Education

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

92

The Phosphoinositide 3-Kinase Isoform PI3Kβ Regulates Osteoclast-Mediated Bone Resorption in Humans and Mice

Győri, Dávid, Csete, Dániel, Benkő, Szilvia, Kulkarni, Suhasini, Mandl, Péter, Dobó-Nagy, Csaba, Vanhaesebroeck, Bart, Stephens, Len, Hawkins, Phillip T., Mócsai, Attila

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

93

A biopsychosocial model for depressive symptoms following acute coronary syndromes

Di Benedetto, Mirella, Len Burns, G., Lindner, Helen, Kent, Stephen

Journal:

Psychology and Health

Year:

2010

Language:

english

File:

PDF, 329 KB

english, 2010

94

Regulation of P-Rex1 by Phosphatidylinositol (3,4,5)-Trisphosphate and Gβγ Subunits

Hill, Kirsti, Krugmann, Sonja, Andrews, Simon R., Coadwell, W. John, Finan, Peter, Welch, Heidi C. E., Hawkins, Phillip T., Stephens, Len R.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 903 KB

english, 2005

95

Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP2 in the Mouse

Anderson, Karen E., Kielkowska, Anna, Durrant, Tom N., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T., Mohanraj, Rajesh

Journal:

Year:

2013

Language:

english

File:

PDF, 926 KB

english, 2013

96

More Paths to PI3Kγ

Stephens, Len, Hawkins, Phillip

Journal:

Year:

2013

Language:

english

File:

PDF, 476 KB

english, 2013

97

Challenges in the development of e-health strategies for geriatric medicine

Wright, Olivia, Wootton, Richard, Margolis, Stephen, Scuffham, Paul, Gray, Len

Journal:

Journal of Telemedicine and Telecare

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

98

A phase I study of intravenous plerixafor following cyclophosphamide mobilization in patients with multiple myeloma

Krishnan, Amrita Y., Wang, Shirong, Palmer, Joycelynne M., Tsai, Ni-Chun, Thomas, Sandra H., Htut, Myo, Farol, Len, Forman, Stephen J.

Journal:

Leukemia and Lymphoma

Year:

2014

Language:

english

File:

PDF, 191 KB

english, 2014

99

Point Transect Sampling with Traps or Lures

Stephen T. Buckland, Ron W. Summers, David L. Borchers and Len Thomas

Journal:

Journal of Applied Ecology

Year:

2006

Language:

english

File:

PDF, 1.43 MB

english, 2006

100

1-Phosphatidylinositol 3-Kinase Activity is Required for Insulin-Stimulated Glucose Transport But not for RAS Activation in CHO Cells

Kenta Hara, Kazuyoshi Yonezawa, Hiroshi Sakaue, Akifumi Ando, Kei Kotani, Tadahiro Kitamura, Yukari Kitamura, Hiroo Ueda, Len Stephens, Trevor R. Jackson, Michael D. Waterfield and Masato Kasuga

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 988 KB

english, 1994