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1

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects

Christakos, Sylvia, Dhawan, Puneet, Verstuyf, Annemieke, Verlinden, Lieve, Carmeliet, Geert

Journal:

Physiological Reviews

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

2

New aspects of vitamin D metabolism and action â addressing the skin as source and target

Bikle, Daniel, Christakos, Sylvia

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2020

Language:

english

File:

PDF, 2.34 MB

english, 2020

3

Mechanism of action of 1,25-dihydroxyvitamin D3on intestinal calcium absorption

Sylvia Christakos

Journal:

Reviews in Endocrine & Metabolic Disorders

Year:

2012

Language:

english

File:

PDF, 186 KB

english, 2012

4

Mechanisms Underlying the Regulation of Innate and Adaptive Immunity by Vitamin D

Wei, Ran, Christakos, Sylvia

Journal:

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

5

New insights into the mechanisms of vitamin D action

Sylvia Christakos, Puneet Dhawan, Yan Liu, Xiaorong Peng, Angela Porta

Journal:

Journal of Cellular Biochemistry

Year:

2003

Language:

english

File:

PDF, 279 KB

english, 2003

6

Calcium Binding Protein in Squid Brain: Biochemical Similarity to the 28,000-Mr Vitamin D-Dependent Calcium Binding Protein (Calbindin-D28k)

Sylvia Christakos, Lorraine Malkowitz, Alan Sori, Andrea Sperduto, Susan C. Feldman

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 2.11 MB

english, 1987

7

Biological actions and mechanism of action of calbindin in the process of apoptosis

Sylvia Christakos, Yan Liu

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

8

Vitamin D and intestinal calcium absorption

Sylvia Christakos, Puneet Dhawan, Angela Porta, Leila J. Mady, Tanya Seth

Journal:

Molecular and Cellular Endocrinology

Year:

2011

Language:

english

File:

PDF, 206 KB

english, 2011

9

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

Cheng, Bin, Christakos, Sylvia, Mattson, Mark P.

Journal:

Year:

1994

Language:

english

File:

PDF, 9.34 MB

english, 1994

10

Biology and Mechanisms of Action of the Vitamin D Hormone

Pike, J. Wesley, Christakos, Sylvia

Journal:

Endocrinology and Metabolism Clinics of North America

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

11

New developments in our understanding of vitamin metabolism, action and treatment

Christakos, Sylvia, Li, ShanShan, De La Cruz, Jessica, Bikle, Daniel D.

Journal:

Year:

2019

File:

PDF, 2.48 MB

2019

12

Early climbing fiber interactions with Purkinje cells in the postnatal mouse cerebellum

Dr. Carol A. Mason, Sylvia Christakos, Susan M. Catalano

Journal:

The Journal of Comparative Neurology

Year:

1990

Language:

english

File:

PDF, 1.52 MB

english, 1990

13

Cerebellar Purkinje cell markers are expressed in retinal bipolar neurons

Albert S. Berrebi, John Oberdick, Lakshmi Sangameswaran, Sylvia Christakos, James I. Morgan, Enrico Mugnaini

Journal:

The Journal of Comparative Neurology

Year:

1991

Language:

english

File:

PDF, 2.57 MB

english, 1991

14

Vitamin D and multiple sclerosis

Anita Raghuwanshi, Sneha S. Joshi, Sylvia Christakos

Journal:

Journal of Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 99 KB

english, 2008

15

Novel regulation of 25-hydroxyvitamin D3 24-hydroxylase (24(OH)ase) transcription by glucocorticoids: Cooperative effects of the glucocorticoid receptor, C/EBPβ, and the Vitamin D receptor in 24(OH)ase transcription

Puneet Dhawan, Sylvia Christakos

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 4.55 MB

english, 2010

16

The nuclear receptor superfamily of steroid hormones and vitamin D gene regulation : An update

Ronald N. Margolis, Sylvia Christakos

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

17

New Insights into the Mechanisms Involved in the Pleiotropic Actions of 1,25Dihydroxyvitamin D3

SYLVIA CHRISTAKOS, PUNEET DHAWAN, QI SHEN, XIAORONG PENG, BRYAN BENN, YAN ZHONG

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

18

Enhanced Coactivator Binding and Transcriptional Activation of Mutant Vitamin D Receptors From Patients With Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets by Phosphorylation and Vitamin D Analogs

Yan Liu, Qi Shen, Peter J Malloy, Emad Soliman, Xiaorong Peng, Sungtae Kim, J Wesley Pike, David Feldman, Sylvia Christakos

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 478 KB

english, 2005

19

1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects

Qin Wang, Dawn Lee, Vilayvanh Sysounthone, Roshantha A.S. Chandraratna, Sylvia Christakos, Reju Korah, Robert Wieder

Journal:

Breast Cancer Research and Treatment

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

20

Effect of 1,25,28-trihydroxyvitamin D2 and 1,24,25-trihydroxyvitamin D3 on intestinal calbindin-D9K mRNA and protein: Is there a correlation with intestinal calcium transport?

Y.-Z. Wang, H. Li, M.E. Bruns, M. Uskokovic, G.A. Truitt, R. Horst, T. Reinhardt, Dr. Sylvia Christakos

Journal:

Journal of Bone and Mineral Research

Year:

1993

Language:

english

File:

PDF, 766 KB

english, 1993

21

Age and gender effects on 1,25-dihydroxyvitamin D3-regulated gene expression

Julie A. Johnson, Matthew J. Beckman, Angela Pansini-Porta, Sylvia Christakos, M.Elizabeth Bruns, Donald C. Beitz, Ronald L. Horst, Timothy A. Reinhardt

Journal:

Experimental Gerontology

Year:

1995

Language:

english

File:

PDF, 825 KB

english, 1995

22

Vitamin D-dependent calcium-binding protein synthesis by chick kidney and duodenal polysomes

Sylvia Christakos, Anthony W. Norman

Journal:

Archives of Biochemistry and Biophysics

Year:

1980

Language:

english

File:

PDF, 675 KB

english, 1980

23

Multiple sites of action of the vitamin D endocrine system: FSH stimulation of testis 1,25-dihydroxyvitamin D3 receptors

Blake C. Osmundsen, Hosea F.S. Huang, Mary B. Anderson, Sylvia Christakos, Marian R. Walters

Journal:

Journal of Steroid Biochemistry

Year:

1989

Language:

english

File:

PDF, 552 KB

english, 1989

24

Vitamin D: Is the brain a target?

Victoria N. Luine, June Sonnenberg, Sylvia Christakos

Journal:

Year:

1987

Language:

english

File:

PDF, 1.09 MB

english, 1987

25

Calbindin D9k is not required for 1,25-dihydroxyvitamin D3-mediated Ca2+ absorption in small intestine

Shirin Akhter, Galina D. Kutuzova, Sylvia Christakos, Hector F. DeLuca

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 200 KB

english, 2007

26

Recent advances in our understanding of 1,25-dihydroxyvitamin D3 regulation of intestinal calcium absorption

Sylvia Christakos

Journal:

Archives of Biochemistry and Biophysics

Year:

2012

Language:

english

File:

PDF, 330 KB

english, 2012

27

Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression

Michael Centrella, Sylvia Christakos, Thomas L. McCarthy

Journal:

Year:

2004

Language:

english

File:

PDF, 270 KB

english, 2004

28

New insights into the function and regulation of vitamin D target proteins

Sylvia Christakos, Puneet Dhawan, Xiaorong Peng, Alexander G. Obukhov, Martha C. Nowycky, Bryan S. Benn, Yan Zhong, Yan Liu, Qi Shen

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 437 KB

english, 2007

29

Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D

Sylvia Christakos, Puneet Dhawan, Dare Ajibade, Bryan S. Benn, Jingjing Feng, Sneha S. Joshi

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 657 KB

english, 2010

30

Vitamin D: Metabolism

Sylvia Christakos, Dare V. Ajibade, Puneet Dhawan, Adam J. Fechner, Leila J. Mady

Journal:

Rheumatic Disease Clinics of North America

Year:

2012

Language:

english

File:

PDF, 233 KB

english, 2012

31

Vitamin D-Dependent Calcium-Binding Protein Is Highly Conserved in the Metanephros

WILLIAM B. RHOTEN, SYLVIA CHRISTAKOS

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 263 KB

english, 1984

32

Evidence that sodium deprivation influences vitamin D dependent rat renal calcium binding protein

Angela R. Pansini, Sylvia Christakos

Journal:

Year:

1983

File:

PDF, 332 KB

1983

33

Apoptosis and signal transduction: clues to a molecular mechanism

Lee, Sooja, Christakos, Sylvia, Small, Michael B.

Journal:

Current Opinion in Cell Biology

Year:

1993

Language:

english

File:

PDF, 614 KB

english, 1993

34

Vitamin D: Metabolism

Christakos, Sylvia, Ajibade, Dare V., Dhawan, Puneet, Fechner, Adam J., Mady, Leila J.

Journal:

Endocrinology and Metabolism Clinics of North America

Year:

2010

Language:

english

File:

PDF, 228 KB

english, 2010

35

Calcium binding protein (calbindin-D28k) and glutamate decarboxylase gene expression after kindling induced seizures

Sonnenberg, June L., Frantz, Gretchen D., Lee, Soohee, Heick, Alison, Chu, Ching, Tobin, Allan J., Christakos, Sylvia

Journal:

Molecular Brain Research

Year:

1991

Language:

english

File:

PDF, 1.58 MB

english, 1991

36

Calbindin D28k Blocks the Proapoptotic Actions of Mutant Presenilin 1: Reduced Oxidative Stress and Preserved Mitochondrial Function

Qing Guo, Sylvia Christakos, Nic Robinson and Mark P. Mattson

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.85 MB

english, 1998

37

C/EBPα and the Vitamin D Receptor Cooperate in the Regulation of Cathelicidin in Lung Epithelial Cells

Dhawan, Puneet, Wei, Ran, Sun, Cheng, Gombart, Adrian F., Koeffler, H. Phillip, Diamond, Gill, Christakos, Sylvia

Journal:

Journal of Cellular Physiology

Year:

2015

Language:

english

File:

PDF, 776 KB

english, 2015

38

Vitamin D: beyond bone

Christakos, Sylvia, Hewison, Martin, Gardner, David G., Wagner, Carol L., Sergeev, Igor N., Rutten, Erica, Pittas, Anastassios G., Boland, Ricardo, Ferrucci, Luigi, Bikle, Daniel D.

Journal:

Annals of the New York Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 331 KB

english, 2013

39

Novel Mechanism of Negative Regulation of 1,25-Dihydroxyvitamin D 3 -induced 25-Hydroxyvitamin D 3 24-Hydroxylase ( Cyp24a1 ) Transcription

Seth-Vollenweider, Tanya, Joshi, Sneha, Dhawan, Puneet, Sif, Said, Christakos, Sylvia

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.43 MB

english, 2014

40

Vitamin D endocrine system and the intestine

Christakos, Sylvia, Lieben, Liesbet, Masuyama, Ritsuko, Carmeliet, Geert

Journal:

BoneKEy Reports

Year:

2014

Language:

english

File:

PDF, 994 KB

english, 2014

41

Minireview: Vitamin D: Is There a Role in Extraskeletal Health?

Christakos, Sylvia, DeLuca, Hector F.

Journal:

Year:

2011

Language:

english

File:

PDF, 310 KB

english, 2011

42

Presence and Localization of Two Vitamin D-Dependent Calcium Binding Proteins in Kidneys of Higher Vertebrates*

RHOTEN, WILLIAM B., BRUNS, M. ELIZABETH, CHRISTAKOS, SYLVIA

Journal:

Year:

1985

Language:

english

File:

PDF, 4.31 MB

english, 1985

43

The role of calbindin and 1,25dihydroxyvitamin D3 in the kidney

Sooy, Karen, Kohut, Jody, Christakos, Sylvia

Journal:

Current Opinion in Nephrology & Hypertension

Year:

2000

Language:

english

File:

PDF, 290 KB

english, 2000

44

Genomic mechanisms involved in the pleiotropic actions of 1,25-dihydroxyvitamin D 3

CHRISTAKOS, Sylvia, RAVAL-PANDYA, Mihali, WERNYJ, Roman P., YANG, Wen

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 437 KB

english, 1996

45

Vitamin D, calcium homeostasis and aging

Veldurthy, Vaishali, Wei, Ran, Oz, Leyla, Dhawan, Puneet, Jeon, Yong Heui, Christakos, Sylvia

Journal:

Year:

2016

Language:

english

File:

PDF, 284 KB

english, 2016

46

1,25 (OH)2D3 treatment alters the granulomatous response in M. tuberculosis infected mice

Bhatt, Kamlesh, Rafi, Wasiulla, Shah, Neel, Christakos, Sylvia, Salgame, Padmini

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

47

Highlights from the 19 th Workshop on Vitamin D in Boston, March 29–31, 2016

Christakos, Sylvia, White, John H., Hewison, Martin, Welsh, JoEllen, Lips, Paul, Bouillon, Roger, Demay, Marie B.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2017

Language:

english

File:

PDF, 131 KB

english, 2017

48

In search of regulatory circuits that control the biological activity of vitamin D

Christakos, Sylvia

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 174 KB

english, 2017

49

Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28–31, 2017

Hewison, Martin, Fleet, James C., Demay, Marie B., Christakos, Sylvia, Bouillon, Roger, Welsh, JoEllen, White, John H.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2017

Language:

english

File:

PDF, 135 KB

english, 2017

50

Transgenic Expression of the Vitamin D Receptor Restricted to the Ileum, Cecum, and Colon of Vitamin D Receptor Knockout Mice Rescues Vitamin D Receptor−Dependent Rickets

Dhawan, Puneet, Veldurthy, Vaishali, Yehia, Ghassan, Hsaio, Connie, Porta, Angela, Kim, Ki-in, Patel, Nishant, Lieben, Liesbet, Verlinden, Lieve, Carmeliet, Geert, Christakos, Sylvia

Journal:

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017